CA2089728A1 - Acides pyridylthio- ou pyridyloxyalcanoiques - Google Patents

Acides pyridylthio- ou pyridyloxyalcanoiques

Info

Publication number
CA2089728A1
CA2089728A1 CA002089728A CA2089728A CA2089728A1 CA 2089728 A1 CA2089728 A1 CA 2089728A1 CA 002089728 A CA002089728 A CA 002089728A CA 2089728 A CA2089728 A CA 2089728A CA 2089728 A1 CA2089728 A1 CA 2089728A1
Authority
CA
Canada
Prior art keywords
pyridyl
compound
propionic acid
phenyloctyl
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002089728A
Other languages
English (en)
Inventor
James S. Frazee
John G. Gleason
Ralph F. Hall
Charles M. Kinzig
Irene N. Uzinskas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2089728A1 publication Critical patent/CA2089728A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/70Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55Acids; Esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
CA002089728A 1990-09-13 1991-09-10 Acides pyridylthio- ou pyridyloxyalcanoiques Abandoned CA2089728A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58195890A 1990-09-13 1990-09-13
US581,958 1990-09-13

Publications (1)

Publication Number Publication Date
CA2089728A1 true CA2089728A1 (fr) 1992-03-14

Family

ID=24327273

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002089728A Abandoned CA2089728A1 (fr) 1990-09-13 1991-09-10 Acides pyridylthio- ou pyridyloxyalcanoiques

Country Status (10)

Country Link
EP (1) EP0548291A1 (fr)
JP (1) JPH06501019A (fr)
KR (1) KR930702304A (fr)
AU (1) AU8900391A (fr)
CA (1) CA2089728A1 (fr)
IE (1) IE913214A1 (fr)
MX (1) MX9101098A (fr)
PT (1) PT98974A (fr)
WO (1) WO1992005156A1 (fr)
ZA (1) ZA917261B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856322A (en) * 1990-10-12 1999-01-05 Merck Frosst Canada, Inc. Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists
JP3181917B2 (ja) * 1992-06-30 2001-07-03 スミスクライン・ビーチャム・コーポレイション フェニルチオメチルピリジニルアルケノアート類の製造方法
ES2065234B1 (es) * 1992-10-27 1995-09-01 Smithkline Beecham Corp Compuestos para tratar enfermedades relacionadas con los leucotrienos.
AR029004A1 (es) * 1999-09-22 2003-06-04 Essential Therapeutics Inc Compuesto del acido 7-acilamino-3-heteroariltio-3-cefem carboxilico y su uso para la preparacion de una composicion antibacteriana
FR2885616B1 (fr) 2005-05-12 2007-06-22 Servier Lab Nouveaux derives de phenylpyridinylpiperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2885615B1 (fr) * 2005-05-12 2007-06-22 Servier Lab Nouveaux derives de phenylpyridinylpiperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4920131A (en) * 1987-11-03 1990-04-24 Rorer Pharmaceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4

Also Published As

Publication number Publication date
IE913214A1 (en) 1992-02-25
ZA917261B (en) 1992-09-30
EP0548291A1 (fr) 1993-06-30
MX9101098A (es) 1992-05-04
AU8900391A (en) 1992-04-15
WO1992005156A1 (fr) 1992-04-02
KR930702304A (ko) 1993-09-08
JPH06501019A (ja) 1994-01-27
PT98974A (pt) 1992-08-31

Similar Documents

Publication Publication Date Title
EP0223593B1 (fr) Acides et esters phénoxyalcoylcarboxyliques, leur préparation ainsi que leur formule pharmaceutique
CA2089728A1 (fr) Acides pyridylthio- ou pyridyloxyalcanoiques
AU620037B2 (en) Leukotriene antagonists
AU4545893A (en) Pharmaceutical pyridine compounds
WO1994014797A1 (fr) Composes de quinoline utilises dans le traitement de maladies associees aux leucotrienes
US4937253A (en) Ester prodrugs
EP0375348B1 (fr) Antagonistes de leukotriène
AU610528B2 (en) Leukotriene antagonists
US5569677A (en) Diphenyl-2-propenoates for treating diseases associated with leukotriene B4
US5135938A (en) Leukotriene antagonists
US5314918A (en) Leukotriene antagonists
AU7902991A (en) Five-membered ring alkanoic acid leukotriene antagonists
EP0732919A1 (fr) Diphenyl-2-propenoates et leurs homologues, utiles dans le traitement des maladies associees a la leucotriene b4
US5143931A (en) Leukotriene antagonists containing tetrazolyl groups
IE902141A1 (en) Leukotriene antagonists
US5189226A (en) Ortho-substituted benzaldehydes
AU7769491A (en) 3-naphthyl-3-carboxyalkylthio or oxy substituted alkanoic acid leukotriene antagonists
HU184679B (en) Process for preparing indanyl derivatives
EP0733044A1 (fr) Composes
WO1993011768A1 (fr) Composes a base de pyridyle destines au traitement du psoriasis
JPH08505148A (ja) ロイコトリエンアンタゴニストとして有用な置換ピリジル化合物

Legal Events

Date Code Title Description
FZDE Dead