IL148593A0 - T2r, a novel family of taste receptors - Google Patents
T2r, a novel family of taste receptorsInfo
- Publication number
- IL148593A0 IL148593A0 IL14859300A IL14859300A IL148593A0 IL 148593 A0 IL148593 A0 IL 148593A0 IL 14859300 A IL14859300 A IL 14859300A IL 14859300 A IL14859300 A IL 14859300A IL 148593 A0 IL148593 A0 IL 148593A0
- Authority
- IL
- Israel
- Prior art keywords
- taste receptors
- novel family
- family
- novel
- receptors
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Endocrinology (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/393,634 US6558910B2 (en) | 1999-09-10 | 1999-09-10 | SF, a novel family of taste receptors |
US09/510,332 US7244584B2 (en) | 1999-09-10 | 2000-02-22 | T2R, a novel family of taste receptors |
PCT/US2000/024821 WO2001018050A2 (en) | 1999-09-10 | 2000-09-08 | T2r taste receptor family |
Publications (1)
Publication Number | Publication Date |
---|---|
IL148593A0 true IL148593A0 (en) | 2002-09-12 |
Family
ID=27014384
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14859300A IL148593A0 (en) | 1999-09-10 | 2000-09-08 | T2r, a novel family of taste receptors |
Country Status (10)
Country | Link |
---|---|
US (8) | US7465550B2 (ja) |
EP (1) | EP1214343A2 (ja) |
JP (1) | JP4339542B2 (ja) |
CN (1) | CN1289525C (ja) |
AU (2) | AU773600B2 (ja) |
CA (1) | CA2384777A1 (ja) |
IL (1) | IL148593A0 (ja) |
MX (1) | MXPA02002538A (ja) |
NO (1) | NO20021164L (ja) |
WO (1) | WO2001018050A2 (ja) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU773600B2 (en) | 1999-09-10 | 2004-05-27 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | T2R, taste receptor family |
US6558910B2 (en) | 1999-09-10 | 2003-05-06 | The Regents Of The University Of California | SF, a novel family of taste receptors |
TW201006846A (en) | 2000-03-07 | 2010-02-16 | Senomyx Inc | T1R taste receptor and genes encidung same |
AU2001251258B2 (en) * | 2000-04-07 | 2008-06-05 | Senomyx, Inc. | T2r taste receptors and genes encoding same |
TW201022287A (en) * | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
US20080244761A1 (en) | 2001-03-07 | 2008-10-02 | Senomyx, Inc. | T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds |
US7368285B2 (en) | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
US7301009B2 (en) | 2001-06-26 | 2007-11-27 | Senomyx, Inc. | Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli |
US7883856B2 (en) | 2001-04-05 | 2011-02-08 | Senomyx Inc. | Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators |
US8030008B2 (en) | 2001-04-05 | 2011-10-04 | Senomyx, Inc. | Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators |
US7803982B2 (en) | 2001-04-20 | 2010-09-28 | The Mount Sinai School Of Medicine Of New York University | T1R3 transgenic animals, cells and related methods |
DK2327985T3 (en) | 2001-06-26 | 2016-09-05 | Senomyx Inc | H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds |
EP2293067B1 (en) | 2001-06-26 | 2016-04-20 | Senomyx, Inc. | T1R hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds |
CA2452337A1 (en) * | 2001-07-10 | 2003-01-23 | Senomyx, Inc. | Use of specific t2r taste receptors to identify compounds that block bitter taste |
EP1523308A4 (en) * | 2001-07-20 | 2007-01-10 | Us Gov Health & Human Serv | PHENYL THIOCARBAMIDE (PTC) TREATMENT RECEPTOR |
JP2005522187A (ja) * | 2001-10-12 | 2005-07-28 | ザ レジェンツ オブ ザ ユニバーシティー オブ カリフォルニア サン ディエゴ | 胃腸化学感覚受容体 |
IL165669A0 (en) | 2002-07-29 | 2006-01-15 | Senomyx Inc | Identification of a novel bitter taste receptor t2r76 |
WO2004029087A2 (en) * | 2002-09-25 | 2004-04-08 | Deutsches Institut für Ernährungsforschung | Bitter taste receptors |
CN1726224A (zh) | 2002-12-18 | 2006-01-25 | 吉万奥丹股份有限公司 | 嵌合αQ-Gustducin G-蛋白 |
US7579453B2 (en) | 2003-06-19 | 2009-08-25 | The United States Of America As Represented By The Secretary Of The Dapartment Of Health And Human Services | Variants of human taste receptor genes |
US7829299B2 (en) | 2004-11-18 | 2010-11-09 | Deutsches Institut fur Ernahrungforschung Potsdam-Rehbrucke Stiftung des Offentlichen Rechts | Agonists of bitter taste receptors and uses thereof |
CA2597085A1 (en) * | 2005-02-08 | 2006-08-17 | Senomyx, Inc. | Phuman t2r receptors for acetaminophen, ranitidine, strychnine and denatonium and related assays for identifying human bitter taste modulators |
US8017336B2 (en) | 2005-12-27 | 2011-09-13 | Nihon University | Method of examining zinc-deficient taste disturbance by determining expression level of taste receptor genes |
KR101356892B1 (ko) | 2006-04-20 | 2014-01-28 | 지보당 에스아 | 미각자극물질을 동정하는 기능적인 방법 |
US20110097741A1 (en) * | 2006-04-20 | 2011-04-28 | Jay Patrick Slack | Partial t1r2 nucleic acid sequence, receptor protein and its use in screening assays |
JP6095881B2 (ja) | 2006-04-20 | 2017-03-15 | ジボダン エス エー | 甘味増強に関する方法 |
US7811788B2 (en) * | 2006-09-05 | 2010-10-12 | Senomyx Inc. | Nucleic acid encoding a haplotype of human T2R receptor hT2R50 |
US8039233B2 (en) | 2007-01-18 | 2011-10-18 | Givaudan S.A. | Nucleic acid sequences and their use in methods to identify umami modulatiors |
EP2137322B1 (en) | 2007-03-30 | 2013-02-27 | Givaudan SA | Methods to identify tas2r modulators |
US7932058B2 (en) | 2007-06-08 | 2011-04-26 | Senomyx, Inc. | Rationale, methods, and assays for identifying human and non-human primate taste specific genes and use thereof in taste modulator and therapeutic screening assays |
WO2009025793A2 (en) | 2007-08-21 | 2009-02-26 | Senomyx, Inc. | Human t2r bitterness receptors and uses thereof |
US20110003711A1 (en) * | 2008-02-01 | 2011-01-06 | Chromocell Corporation | Cell lines expressing gaba receptor and methods using them |
US9525148B2 (en) | 2008-04-03 | 2016-12-20 | Qd Vision, Inc. | Device including quantum dots |
SG184962A1 (en) | 2010-05-07 | 2012-11-29 | Givaudan Sa | Methods to identify modulators of tas2r4s receptors |
US20130115624A1 (en) | 2010-05-07 | 2013-05-09 | Givaudan S.A. | Methods To Identify Modulators |
CN103068380A (zh) * | 2010-06-17 | 2013-04-24 | 加州理工学院 | 用于调节激素的方法和系统以及相关的方法、剂和组合物 |
US9128079B2 (en) | 2011-08-08 | 2015-09-08 | The Coca-Cola Company | Methods of using lung or bronchial epithelial cells to identify bitter taste modulators |
WO2013159227A1 (en) * | 2012-04-25 | 2013-10-31 | University Of Manitoba | Bitter taste receptor constitutively active mutants |
US9169311B2 (en) | 2013-03-15 | 2015-10-27 | Applied Food Biotechnology, Inc. | Feline bitter taste receptors and methods |
US9804157B1 (en) | 2013-03-15 | 2017-10-31 | Senomyx, Inc. | Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives |
ES2797547T3 (es) | 2013-03-15 | 2020-12-02 | Applied Food Biotech Inc | Receptores del sabor amargo felino y métodos. |
AU2014262540B2 (en) * | 2013-05-10 | 2016-10-27 | Pepsico, Inc. | Taste receptor internalization assay |
JP6367315B2 (ja) | 2013-05-10 | 2018-08-01 | ペプシコ, インコーポレイテッドPepsiCo Inc. | 潜在的味覚調節物質を特定するためのモデルとしての細胞 |
ES2802376T3 (es) | 2014-02-12 | 2021-01-19 | Firmenich Incorporated | Procedimiento mejorado para la síntesis de 1-bencil-3-(1-(isoxazol-4-ilmetil)-1h-pirazol-4-il)imidazolidin-2,4-dionas sustituidas |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU3665893A (en) | 1992-02-12 | 1993-09-03 | United States Of America, As Represented By The Secretary, Department Of Health And Human Services, The | Sequences characteristic of human gene transcription product |
NZ334517A (en) | 1996-09-04 | 2000-03-27 | Mogen Internat Nv | Antifungal plant proteins and method of inhibiting fungal growth with carbohydrate oxidising activity and DNA coding sequences thereof |
JP2002504488A (ja) | 1998-02-18 | 2002-02-12 | ジェネティックス・インスチチュート・インコーポレーテッド | 分泌蛋白およびそれらをコードするポリヌクレオチド |
WO2000038536A2 (en) | 1998-12-23 | 2000-07-06 | Mount Sinai School Of Medicine Of New York University | Inhibitors of the bitter taste response |
AU773600B2 (en) | 1999-09-10 | 2004-05-27 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | T2R, taste receptor family |
US6558910B2 (en) | 1999-09-10 | 2003-05-06 | The Regents Of The University Of California | SF, a novel family of taste receptors |
-
2000
- 2000-09-08 AU AU73664/00A patent/AU773600B2/en not_active Ceased
- 2000-09-08 CA CA002384777A patent/CA2384777A1/en not_active Abandoned
- 2000-09-08 IL IL14859300A patent/IL148593A0/xx unknown
- 2000-09-08 EP EP00961750A patent/EP1214343A2/en not_active Withdrawn
- 2000-09-08 MX MXPA02002538A patent/MXPA02002538A/es active IP Right Grant
- 2000-09-08 CN CNB00815435XA patent/CN1289525C/zh not_active Expired - Fee Related
- 2000-09-08 WO PCT/US2000/024821 patent/WO2001018050A2/en active IP Right Grant
- 2000-09-08 JP JP2001522272A patent/JP4339542B2/ja not_active Expired - Fee Related
-
2002
- 2002-03-08 NO NO20021164A patent/NO20021164L/no not_active Application Discontinuation
-
2004
- 2004-08-10 AU AU2004203826A patent/AU2004203826A1/en not_active Abandoned
- 2004-10-07 US US10/962,365 patent/US7465550B2/en not_active Expired - Fee Related
-
2007
- 2007-10-25 US US11/978,088 patent/US7595166B2/en not_active Expired - Fee Related
-
2009
- 2009-08-20 US US12/544,854 patent/US7868150B2/en not_active Expired - Fee Related
-
2010
- 2010-12-13 US US12/966,955 patent/US8329885B2/en not_active Expired - Fee Related
-
2012
- 2012-11-01 US US13/666,740 patent/US8624012B2/en not_active Expired - Fee Related
-
2013
- 2013-11-20 US US14/085,403 patent/US9063124B2/en not_active Expired - Fee Related
-
2015
- 2015-05-19 US US14/716,733 patent/US9817000B2/en not_active Expired - Fee Related
-
2017
- 2017-10-17 US US15/786,468 patent/US20180128842A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US8329885B2 (en) | 2012-12-11 |
US20050048586A1 (en) | 2005-03-03 |
WO2001018050A2 (en) | 2001-03-15 |
NO20021164L (no) | 2002-05-10 |
JP4339542B2 (ja) | 2009-10-07 |
MXPA02002538A (es) | 2005-07-01 |
JP2003510037A (ja) | 2003-03-18 |
AU2004203826A1 (en) | 2004-09-16 |
US20140120553A1 (en) | 2014-05-01 |
US20100062456A1 (en) | 2010-03-11 |
US9063124B2 (en) | 2015-06-23 |
CN1289525C (zh) | 2006-12-13 |
US7868150B2 (en) | 2011-01-11 |
WO2001018050A9 (en) | 2002-02-07 |
US20150260733A1 (en) | 2015-09-17 |
US20180128842A1 (en) | 2018-05-10 |
EP1214343A2 (en) | 2002-06-19 |
WO2001018050A3 (en) | 2002-01-10 |
US20120009598A1 (en) | 2012-01-12 |
AU7366400A (en) | 2001-04-10 |
US7595166B2 (en) | 2009-09-29 |
US20080108088A1 (en) | 2008-05-08 |
US9817000B2 (en) | 2017-11-14 |
NO20021164D0 (no) | 2002-03-08 |
CN1387536A (zh) | 2002-12-25 |
AU773600B2 (en) | 2004-05-27 |
US8624012B2 (en) | 2014-01-07 |
US7465550B2 (en) | 2008-12-16 |
CA2384777A1 (en) | 2001-03-15 |
US20130189712A1 (en) | 2013-07-25 |
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