IL148360A0 - A herpes viral mutant and pharmaceutical compositions containing the same - Google Patents
A herpes viral mutant and pharmaceutical compositions containing the sameInfo
- Publication number
- IL148360A0 IL148360A0 IL14836000A IL14836000A IL148360A0 IL 148360 A0 IL148360 A0 IL 148360A0 IL 14836000 A IL14836000 A IL 14836000A IL 14836000 A IL14836000 A IL 14836000A IL 148360 A0 IL148360 A0 IL 148360A0
- Authority
- IL
- Israel
- Prior art keywords
- same
- pharmaceutical compositions
- compositions containing
- herpes viral
- viral mutant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16041—Use of virus, viral particle or viral elements as a vector
- C12N2710/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16641—Use of virus, viral particle or viral elements as a vector
- C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15162199P | 1999-08-31 | 1999-08-31 | |
PCT/US2000/002409 WO2001016331A1 (en) | 1999-08-31 | 2000-02-02 | Cell-specific and/or tumor-specific promoter retargeting of herpes gamma 34.5 gene expression |
Publications (1)
Publication Number | Publication Date |
---|---|
IL148360A0 true IL148360A0 (en) | 2002-09-12 |
Family
ID=22539547
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14836000A IL148360A0 (en) | 1999-08-31 | 2000-02-02 | A herpes viral mutant and pharmaceutical compositions containing the same |
IL148360A IL148360A (en) | 1999-08-31 | 2002-02-25 | Mutant of herpes virus and pharmaceuticals containing it |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL148360A IL148360A (en) | 1999-08-31 | 2002-02-25 | Mutant of herpes virus and pharmaceuticals containing it |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1212428B1 (ja) |
JP (1) | JP4551042B2 (ja) |
KR (1) | KR100701905B1 (ja) |
AT (1) | ATE283921T1 (ja) |
AU (1) | AU781219B2 (ja) |
CA (1) | CA2383372C (ja) |
DE (1) | DE60016429T2 (ja) |
ES (1) | ES2233349T3 (ja) |
IL (2) | IL148360A0 (ja) |
MX (1) | MXPA02002142A (ja) |
PT (1) | PT1212428E (ja) |
SI (1) | SI1212428T1 (ja) |
WO (1) | WO2001016331A1 (ja) |
ZA (1) | ZA200202413B (ja) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6897057B1 (en) | 1999-08-31 | 2005-05-24 | The General Hospital Corporation | Cell-specific and/or tumor-specific promoter retargeting of herpes γ 34.5 gene expression |
EP1486212A1 (en) * | 2000-06-01 | 2004-12-15 | Sloan-Kettering Institute For Cancer Research | Combination of a mutant herepes virus and irinotecan for the treatment of cancer |
GB0203285D0 (en) | 2002-02-12 | 2002-03-27 | Brown Susanne M | An herpes simplex virus complex |
EP2305710A3 (en) | 2002-06-03 | 2013-05-29 | Genentech, Inc. | Synthetic antibody phage libraries |
GB0326798D0 (en) * | 2003-11-17 | 2003-12-24 | Crusade Lab Ltd | Methods for generating mutant virus |
EP1694852B1 (en) | 2003-11-17 | 2010-10-13 | Crusade Laboratories Limited | Mutant herpes simplex virus and use thereof in the treatment of squamous cell cancer |
US7897146B2 (en) | 2003-11-17 | 2011-03-01 | Crusade Laboratories Limited | Treatment using herpes simplex virus |
US8945531B2 (en) | 2010-02-19 | 2015-02-03 | The University Of Tokyo | Recombinant herpes virus and pharmaceutical composition containing the same |
EP3011964A1 (en) * | 2014-10-24 | 2016-04-27 | Karcinolys | Compounds and associations for treating pancreatic cancer |
US20190328783A1 (en) * | 2016-04-15 | 2019-10-31 | Cellectis | A method of engineering prodrug-specific hypersensitive t-cells for immunotherapy by gene expression |
EP3429633B1 (en) | 2016-04-15 | 2021-02-24 | Cellectis | A method of engineering drug-specific hypersensitive t-cells for immunotherapy by gene inactivation |
CN116135972A (zh) * | 2021-11-16 | 2023-05-19 | 中国科学院深圳先进技术研究院 | 基于中国hsv临床分离株的溶瘤病毒及其构建方法和应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5585096A (en) * | 1994-06-23 | 1996-12-17 | Georgetown University | Replication-competent herpes simplex virus mediates destruction of neoplastic cells |
GB9415320D0 (en) * | 1994-07-29 | 1994-09-21 | Medical Res Council | Cancer treatment |
ZA966287B (en) * | 1995-07-27 | 1998-03-09 | American Cyanamid Co | Avirulent herpetic viruses useful as tumoricidal agents and vaccines. |
WO1998042195A1 (en) * | 1997-03-27 | 1998-10-01 | University Of Cincinnati | Replication-competent herpes simplex viruses |
-
2000
- 2000-02-02 AU AU34774/00A patent/AU781219B2/en not_active Expired
- 2000-02-02 CA CA2383372A patent/CA2383372C/en not_active Expired - Lifetime
- 2000-02-02 ES ES00913305T patent/ES2233349T3/es not_active Expired - Lifetime
- 2000-02-02 WO PCT/US2000/002409 patent/WO2001016331A1/en active IP Right Grant
- 2000-02-02 JP JP2001520877A patent/JP4551042B2/ja not_active Expired - Lifetime
- 2000-02-02 SI SI200030611T patent/SI1212428T1/xx unknown
- 2000-02-02 KR KR1020027002714A patent/KR100701905B1/ko active IP Right Grant
- 2000-02-02 EP EP00913305A patent/EP1212428B1/en not_active Expired - Lifetime
- 2000-02-02 AT AT00913305T patent/ATE283921T1/de active
- 2000-02-02 IL IL14836000A patent/IL148360A0/xx active IP Right Grant
- 2000-02-02 DE DE60016429T patent/DE60016429T2/de not_active Expired - Lifetime
- 2000-02-02 PT PT00913305T patent/PT1212428E/pt unknown
- 2000-02-02 MX MXPA02002142A patent/MXPA02002142A/es active IP Right Grant
-
2002
- 2002-02-25 IL IL148360A patent/IL148360A/en not_active IP Right Cessation
- 2002-03-26 ZA ZA200202413A patent/ZA200202413B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
PT1212428E (pt) | 2005-03-31 |
EP1212428B1 (en) | 2004-12-01 |
WO2001016331A1 (en) | 2001-03-08 |
KR100701905B1 (ko) | 2007-04-02 |
CA2383372C (en) | 2010-04-13 |
DE60016429T2 (de) | 2005-11-24 |
AU781219B2 (en) | 2005-05-12 |
KR20020092905A (ko) | 2002-12-12 |
ATE283921T1 (de) | 2004-12-15 |
IL148360A (en) | 2007-12-03 |
ZA200202413B (en) | 2003-06-25 |
CA2383372A1 (en) | 2001-03-08 |
DE60016429D1 (de) | 2005-01-05 |
AU3477400A (en) | 2001-03-26 |
EP1212428A1 (en) | 2002-06-12 |
ES2233349T3 (es) | 2005-06-16 |
JP2003508055A (ja) | 2003-03-04 |
SI1212428T1 (en) | 2005-06-30 |
JP4551042B2 (ja) | 2010-09-22 |
MXPA02002142A (es) | 2003-04-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed |