IL145795A0 - Mutant human cd80 and compositions for and methods of making and using the same - Google Patents

Mutant human cd80 and compositions for and methods of making and using the same

Info

Publication number
IL145795A0
IL145795A0 IL14579500A IL14579500A IL145795A0 IL 145795 A0 IL145795 A0 IL 145795A0 IL 14579500 A IL14579500 A IL 14579500A IL 14579500 A IL14579500 A IL 14579500A IL 145795 A0 IL145795 A0 IL 145795A0
Authority
IL
Israel
Prior art keywords
methods
same
compositions
making
mutant human
Prior art date
Application number
IL14579500A
Other languages
English (en)
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Publication of IL145795A0 publication Critical patent/IL145795A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70532—B7 molecules, e.g. CD80, CD86
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
IL14579500A 1999-04-30 2000-04-27 Mutant human cd80 and compositions for and methods of making and using the same IL145795A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13176499P 1999-04-30 1999-04-30
PCT/US2000/011310 WO2000066162A1 (en) 1999-04-30 2000-04-27 Mutant human cd80 and compositions for and methods of making and using the same

Publications (1)

Publication Number Publication Date
IL145795A0 true IL145795A0 (en) 2002-07-25

Family

ID=22450922

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14579500A IL145795A0 (en) 1999-04-30 2000-04-27 Mutant human cd80 and compositions for and methods of making and using the same
IL145795A IL145795A (en) 1999-04-30 2001-10-04 Mutant human cd80 and compositions for and methods of making and using the same

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL145795A IL145795A (en) 1999-04-30 2001-10-04 Mutant human cd80 and compositions for and methods of making and using the same

Country Status (13)

Country Link
US (2) US7446189B1 (zh)
EP (1) EP1173204B1 (zh)
JP (1) JP2002542800A (zh)
KR (2) KR100903710B1 (zh)
CN (1) CN1196495C (zh)
AT (1) ATE464910T1 (zh)
AU (1) AU779395B2 (zh)
BR (1) BR0010155A (zh)
CA (1) CA2369747A1 (zh)
DE (1) DE60044247D1 (zh)
IL (2) IL145795A0 (zh)
MX (1) MXPA01011079A (zh)
WO (1) WO2000066162A1 (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7556814B2 (en) * 2003-10-23 2009-07-07 Karp Nelson M Immunogenic compositions comprising UV-irradiated, psoralen-inactivated, desialated human immunodeficiency virus (HIV) devoid of CD55 and CD59 in the viral membrane
US20110104196A1 (en) * 2003-10-23 2011-05-05 Karp Nelson M Immunogenic composition and method of developing a vaccine based on fusion protein
CA2566199C (en) 2004-05-12 2013-10-22 Baxter International Inc. Delivery of as-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes
TW200613554A (en) 2004-06-17 2006-05-01 Wyeth Corp Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to HIV
WO2008037080A1 (en) * 2006-09-29 2008-04-03 Universite De Montreal Methods and compositions for immune response modulation and uses thereof
BR112015013557B1 (pt) 2012-12-11 2021-12-14 Albert Einstein College Of Medicine Sistema, método, método para determinar o efeito de um resíduo de aminoácido predeterminado de uma primeira proteína sobre a ligação da primeira proteína a uma segunda proteína e polipeptídeo pd-l1 mutante
KR20180012260A (ko) 2015-04-17 2018-02-05 알파인 이뮨 사이언시즈, 인코포레이티드 조율가능한 친화성을 갖는 면역조절 단백질
US10402438B2 (en) * 2015-07-20 2019-09-03 Disney Enterprises, Inc. Systems and methods of visualizing multimedia content
CN109715657A (zh) 2016-04-15 2019-05-03 高山免疫科学股份有限公司 Cd80变体免疫调节蛋白及其用途
KR20190019068A (ko) 2016-05-18 2019-02-26 큐 바이오파마, 인크. T-세포 조절 다량체 폴리펩타이드 및 이의 사용 방법
IL262606B2 (en) 2016-05-18 2023-04-01 Albert Einstein College Medicine Inc pd-l1 variant polypeptides, T-cell modulatory multimeric polypeptides, and methods of using them
DK3558339T3 (da) 2016-12-22 2024-02-26 Cue Biopharma Inc T-celle-modulerende multimere polypeptider og fremgangsmåder til anvendelse deraf
WO2018129474A1 (en) 2017-01-09 2018-07-12 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides and methods of use thereof
US20200010528A1 (en) 2017-03-15 2020-01-09 Cue Biopharma, Inc. Methods for modulating an immune response
WO2018170026A2 (en) 2017-03-16 2018-09-20 Alpine Immune Sciences, Inc. Cd80 variant immunomodulatory proteins and uses thereof
EP3737689A4 (en) 2018-01-09 2021-12-01 Cue Biopharma, Inc. MULTIMERIC T CELL-MODULATING POLYPEPTIDES AND METHOD OF USING THEREOF
AU2020262424B2 (en) * 2019-04-26 2023-09-28 Beijing Xuanzhu Combio Co., Ltd. CD80 variant proteins and uses thereof
CA3169949A1 (en) 2020-05-12 2021-11-18 Cue Biopharma, Inc. Multimeric t-cell modulatory polypeptides and methods of use thereof

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077044A (en) 1980-05-19 1991-12-31 The Board Of Trustees Of The Leland Stanford Jr. University Novel non-reverting shigella live vaccines
US4873191A (en) 1981-06-12 1989-10-10 Ohio University Genetic transformation of zygotes
US4722848A (en) 1982-12-08 1988-02-02 Health Research, Incorporated Method for immunizing animals with synthetically modified vaccinia virus
US5338683A (en) 1981-12-24 1994-08-16 Health Research Incorporated Vaccinia virus containing DNA sequences encoding herpesvirus glycoproteins
US5174993A (en) 1981-12-24 1992-12-29 Health Research Inc. Recombinant avipox virus and immunological use thereof
US5110587A (en) 1981-12-24 1992-05-05 Health Research, Incorporated Immunogenic composition comprising synthetically modified vaccinia virus
US4736866B1 (en) 1984-06-22 1988-04-12 Transgenic non-human mammals
US5036006A (en) 1984-11-13 1991-07-30 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
GB8508845D0 (en) 1985-04-04 1985-05-09 Hoffmann La Roche Vaccinia dna
US5223424A (en) 1985-09-06 1993-06-29 Prutech Research And Development Attenuated herpesviruses and herpesviruses which include foreign DNA encoding an amino acid sequence
US5310668A (en) 1986-06-20 1994-05-10 Merck & Co., Inc. Varicella-zoster virus as a live recombinant vaccine
US5242829A (en) 1986-09-23 1993-09-07 Therion Biologics Corporation Recombinant pseudorabies virus
US5387744A (en) 1987-06-04 1995-02-07 Washington University Avirulent microbes and uses therefor: Salmonella typhi
IL86583A0 (en) 1987-06-04 1988-11-15 Molecular Eng Ass Vaccine containing a derivative of a microbe and method for the production thereof
US5294441A (en) 1987-06-04 1994-03-15 Washington University Avirulent microbes and uses therefor: salmonella typhi
US5554528A (en) 1987-08-21 1996-09-10 Board Of Revents Of University Of Colorado Compositions and methods for inhibition of HIV production
US5112749A (en) 1987-10-02 1992-05-12 Praxis Biologics, Inc. Vaccines for the malaria circumsporozoite protein
US5585268A (en) 1987-12-30 1996-12-17 Behringwerke Aktiengesellschaft Malaria-specific DNA sequences, expression products thereof, and the use thereof
US5225336A (en) 1989-03-08 1993-07-06 Health Research Incorporated Recombinant poxvirus host range selection system
WO1990010693A1 (en) 1989-03-08 1990-09-20 Health Research, Inc. Recombinant poxvirus host selection system
DK0465529T3 (da) 1989-03-21 1998-10-05 Vical Inc Ekspression af exogene polynukleotidsekvenser i et hvirveldyr
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
WO1990011687A1 (en) 1989-03-31 1990-10-18 Washington University VACCINES CONTAINING AVIRULENT phoP-TYPE MICROORGANISMS
EP0431668B1 (en) 1989-12-04 1995-02-15 Akzo Nobel N.V. Recombinant herpesvirus of turkeys and live vector vaccines derived thereof
US6641809B1 (en) * 1990-03-26 2003-11-04 Bristol-Myers Squibb Company Method of regulating cellular processes mediated by B7 and CD28
US5294548A (en) 1990-04-02 1994-03-15 American Biogenetic Sciences, Inc Recombianant Hepatitis a virus
US5462734A (en) 1990-11-02 1995-10-31 Wisconsin Alumni Research Foundation Bovine herpesvirus vaccine and method of using same
US5240703A (en) 1991-03-01 1993-08-31 Syntro Corporation Attenuated, genetically-engineered pseudorabies virus s-prv-155 and uses thereof
JP3881689B2 (ja) 1992-03-11 2007-02-14 パウダージェクト ヴァクシンズ，インコーポレイテッド 免疫不全ウイルス用の遺伝子ワクチン
WO1993023552A1 (en) 1992-05-21 1993-11-25 Government Of The United States As Represented By Secretary Department Of Health And Human Services Targeting gene expression to living tissue using jet injection
US5593972A (en) 1993-01-26 1997-01-14 The Wistar Institute Genetic immunization
ATE302854T1 (de) 1993-01-26 2005-09-15 Univ Pennsylvania Zusammensetzungen und verfahren zur verabreichung von genetischem material
US6084067A (en) 1993-07-26 2000-07-04 Dana-Farber Cancer Institute CTLA4/CD28 ligands and uses therefor
US5942607A (en) 1993-07-26 1999-08-24 Dana-Farber Cancer Institute B7-2: a CTLA4/CD28 ligand
JPH09500788A (ja) * 1993-07-26 1997-01-28 ダナ・ファーバー・キャンサー・インスティテュート・インコーポレイテッド Ｂ７−２：ｃｔｌａ４／ｃｄ２８カウンターレセプター
US6218510B1 (en) * 1994-03-02 2001-04-17 Brigham & Woman's Hospital B7-1 and B7-2 polypeptides
US5739118A (en) 1994-04-01 1998-04-14 Apollon, Inc. Compositions and methods for delivery of genetic material
JP2531382B2 (ja) * 1994-05-26 1996-09-04 日本電気株式会社 ボ―ルグリッドアレイ半導体装置およびその製造方法
US5837533A (en) 1994-09-28 1998-11-17 American Home Products Corporation Complexes comprising a nucleic acid bound to a cationic polyamine having an endosome disruption agent
CA2201592A1 (en) * 1994-10-03 1996-04-18 The Government Of The United States Of America, Represented By The Secre Tary, Department Of Health And Human Services Enhanced immune response by introduction of cytokine gene and/or costimulatory molecule b7 gene in a recombinant virus expressing system
CA2323746A1 (en) * 1998-03-19 1999-09-23 Heska Corporation T cell costimulatory proteins, sequences and uses thereof
US6248329B1 (en) * 1998-06-01 2001-06-19 Ramaswamy Chandrashekar Parasitic helminth cuticlin nucleic acid molecules and uses thereof

Also Published As

Publication number Publication date
CN1196495C (zh) 2005-04-13
CA2369747A1 (en) 2000-11-09
US8202847B2 (en) 2012-06-19
JP2002542800A (ja) 2002-12-17
CN1384758A (zh) 2002-12-11
EP1173204A4 (en) 2003-11-05
BR0010155A (pt) 2002-01-15
US7446189B1 (en) 2008-11-04
AU779395B2 (en) 2005-01-20
KR20020047032A (ko) 2002-06-21
EP1173204B1 (en) 2010-04-21
WO2000066162A1 (en) 2000-11-09
IL145795A (en) 2010-02-17
KR20080052690A (ko) 2008-06-11
MXPA01011079A (es) 2002-07-22
DE60044247D1 (de) 2010-06-02
AU4494700A (en) 2000-11-17
US20110002956A1 (en) 2011-01-06
ATE464910T1 (de) 2010-05-15
WO2000066162A9 (en) 2002-01-10
KR100903710B1 (ko) 2009-06-19
EP1173204A1 (en) 2002-01-23

Similar Documents

Publication Publication Date Title
IL145795A0 (en) Mutant human cd80 and compositions for and methods of making and using the same
AP1411A (en) Pyrrolo[2,3d] pyrimidine compositions and their use.
ZA200004819B (en) Mutant recombinant allergens.
WO2003066661A3 (en) Human dr4 antibodies and uses thereof
PL328858A1 (en) Immunogenous peptides
EP0846466A3 (en) Compositions for the treatment of rheumatoid-based arthritic diseases
AU3227700A (en) Skin sanitizing compositions
EP2316466A3 (en) Gram positive bacteria preparations for the treatment of diseases comprising an immune dysregulation
WO2004031129A3 (en) Compounds for use in the treatment of autoimmune diseases, immuno-allergical diseases and organ or tissue transplantation rejection
AU7361900A (en) Methods and compositions for the treatment and prevention of graft rejection using heat shock proteins
IL171384A (en) Use of slurp-1 in the preparation of medicaments for the treatment of neurological disorders
ZA200003768B (en) Methods and compositions for treating diseases and conditions of the eye.
MXPA03003741A (es) Metodos y composiciones para el tratamiento de enfermedades oftalmicas.
TR200200278T2 (tr) Kalsilitik bileşimler
IL153576A0 (en) Dna vaccines encoding hiv accessory proteins
AU2202301A (en) Cd45 inhibitors
WO2002012336A3 (en) TGF-β THERAPEUTICS, COMPOSITIONS AND METHODS OF USE
AU7079300A (en) Compositions and methods for the treatment of immune related diseases
MXPA01010449A (es) Composicion y metodo util para el tratamiento del colico.
AU2002307715A1 (en) Pharmaceutical compositions comprising dendritic cells for immunotherapy of autoimmune disease and treatment methods using the same
AUPP974099A0 (en) Vaccines and methods for the treatment of human melanoma
EP1194162A4 (en) COMPOSITIONS AND METHODS OF PREVENTING, TREATING AND DETECTING TUBERHULOSIS AND OTHER DISEASES
AUPN918296A0 (en) Vaccines and methods for the treatment of human melanoma
AUPO613997A0 (en) Vaccines and methods for the treatment of human melanoma
AUPQ423199A0 (en) Compositions for the treatment of infectious and/or skin diseases