IL145188A0 - Processes for making pharmaceutical oral ecb formulations and compositions - Google Patents

Processes for making pharmaceutical oral ecb formulations and compositions

Info

Publication number
IL145188A0
IL145188A0 IL14518800A IL14518800A IL145188A0 IL 145188 A0 IL145188 A0 IL 145188A0 IL 14518800 A IL14518800 A IL 14518800A IL 14518800 A IL14518800 A IL 14518800A IL 145188 A0 IL145188 A0 IL 145188A0
Authority
IL
Israel
Prior art keywords
ecb
formulations
compositions
processes
pharmaceutical oral
Prior art date
Application number
IL14518800A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL145188A0 publication Critical patent/IL145188A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL14518800A 1999-03-03 2000-03-02 Processes for making pharmaceutical oral ecb formulations and compositions IL145188A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12269399P 1999-03-03 1999-03-03
PCT/US2000/005547 WO2000051567A1 (fr) 1999-03-03 2000-03-02 Procedes permettant de preparer des compositions et des formulations pharmaceutiques orales d'echinocandine b

Publications (1)

Publication Number Publication Date
IL145188A0 true IL145188A0 (en) 2002-06-30

Family

ID=22404178

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14518800A IL145188A0 (en) 1999-03-03 2000-03-02 Processes for making pharmaceutical oral ecb formulations and compositions

Country Status (12)

Country Link
US (1) US6821951B2 (fr)
EP (1) EP1156784A1 (fr)
JP (1) JP2002538097A (fr)
KR (1) KR20010112302A (fr)
CN (1) CN1345230A (fr)
AU (1) AU771727B2 (fr)
BR (1) BR0008713A (fr)
CA (1) CA2362482A1 (fr)
HK (1) HK1040369A1 (fr)
IL (1) IL145188A0 (fr)
WO (1) WO2000051567A1 (fr)
ZA (1) ZA200108001B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743777B1 (en) * 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US6506726B1 (en) 1998-12-09 2003-01-14 Eli Lilly And Company Purification of Echinocandin cyclopeptide compounds
CN1345230A (zh) 1999-03-03 2002-04-17 伊莱利利公司 口服ecb药物制剂和药物组合物的制备方法
ATE338060T1 (de) 1999-03-03 2006-09-15 Lilly Co Eli Bildung und anionenaustausch von inneren kristallinen ammoniumsalzen des echinocandins b
EP1582204B1 (fr) 1999-03-03 2013-09-25 Eli Lilly & Company Formulations pharmaceutiques d'échinocandine contenant des tensioactifs formant des micelles
IL145187A0 (en) 1999-03-03 2002-06-30 Lilly Co Eli Echinocandin/carbohydrate complexes
TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent
AUPR272901A0 (en) * 2001-01-25 2001-02-22 Gainful Plan Limited Method of preparing biological materials and preparations produced using same
US6991800B2 (en) * 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
KR20060004646A (ko) * 2002-08-14 2006-01-12 이 아이 듀폰 디 네모아 앤드 캄파니 고 액체 부하량을 가진 유동성 고상 분말
CA2490601C (fr) * 2003-12-29 2006-05-02 Ferring B.V. Methode de preparation d'une forme pharmaceutique solide de desmopressine
NO2680873T3 (fr) 2011-03-03 2018-01-06
RS64862B1 (sr) 2012-03-19 2023-12-29 Cidara Therapeutics Inc Dozni režimi za jedinjenja klase ehinokandina
CN103330932B (zh) * 2013-04-26 2015-12-23 江苏豪森药业股份有限公司 一种米卡芬净或其盐的药物组合物
WO2017120471A1 (fr) 2016-01-08 2017-07-13 Cidara Therapeutics, Inc. Procédés de prévention et de traitement d'infections à pneumocystis
ES2955711T3 (es) 2016-03-16 2023-12-05 Cidara Therapeutics Inc Regímenes de dosificación para el tratamiento de infecciones fúngicas
US11197909B2 (en) 2017-07-12 2021-12-14 Cidara Therapeutics, Inc. Compositions and methods for the treatment of fungal infections
CN109574811B (zh) * 2018-11-22 2021-12-24 中山大学 一种阿尼芬净侧链中间体对戊氧基三联苯甲酸的制备方法

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3293482A (en) 1962-06-21 1966-12-20 Rca Corp Plural output traveling wave tube
JPS5134916B2 (fr) 1974-03-06 1976-09-29
US4293489A (en) 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912A nucleus
CA1170598A (fr) 1979-12-13 1984-07-10 Bernard J. Abbott Methode de preparation de noyaux peptidiques cycliques
US4299763A (en) 1979-12-13 1981-11-10 Eli Lilly And Company A-30912B Nucleus
US4293482A (en) 1979-12-13 1981-10-06 Eli Lilly And Company A-30912A Nucleus
US4293483A (en) 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912A nucleus
US4304716A (en) 1979-12-13 1981-12-08 Eli Lilly And Company S 31794/F-1 Nucleus
US4320052A (en) 1979-12-13 1982-03-16 Eli Lilly And Company Derivatives of A-30912A nucleus
US4876241A (en) 1987-05-22 1989-10-24 Armour Pharmaceutical Company Stabilization of biological and pharmaceutical products during thermal inactivation of viral and bacterial contaminants
DK173802B1 (da) 1988-09-12 2001-11-05 Merck & Co Inc Præparat til behandling af Pneumocystis carinii infeksioner og anvendelse af et cyclohexapeptid til fremstilling af et lægemiddel mod Pneumocystis carinii infektioner
US5166135A (en) 1988-09-12 1992-11-24 Merck & Company, Inc. Method for the control of pneumocystis carinii
US5202309A (en) 1989-06-30 1993-04-13 Merck & Co., Inc. Antibiotic cyclopeptide fermentation product
JPH03240727A (ja) 1990-02-15 1991-10-28 Toyo Jozo Co Ltd ニューモシスチス・カリニ肺炎治療剤
CA2037957A1 (fr) 1990-03-12 1991-09-13 Merck & Co., Inc. Composes de cyclohexapeptides n-acyles
US5310726A (en) 1990-03-19 1994-05-10 Merck & Co., Inc. Lipopeptide compounds
IL98349A (en) 1990-06-07 1995-05-26 Lilly Co Eli Diphylase lipopeptide
IE912046A1 (en) 1990-06-18 1991-12-18 Fujisawa Pharmaceutical Co New polypeptide compound and a process for preparation¹thereof
US5198421A (en) 1991-04-26 1993-03-30 Merck & Co., Inc. Phosphorylated cyclic lipopeptide
JPH05271097A (ja) 1991-10-07 1993-10-19 Asahi Chem Ind Co Ltd アクレアシン類の可溶化剤および医薬組成物
NZ247149A (en) 1992-03-19 1996-10-28 Lilly Co Eli Cyclic peptide antifungal agents and compositions thereof
US6384013B1 (en) 1992-03-19 2002-05-07 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US5965525A (en) 1992-03-19 1999-10-12 Eli Lilly And Company Cyclic peptide antifungal agents
DE69232220D1 (de) 1992-09-22 2002-01-03 Takeo Takayanagi Kohlenhydrate-Komplexe zur Vernichtung von Krebszellen
JPH06172205A (ja) 1992-12-11 1994-06-21 Asahi Chem Ind Co Ltd アクレアシン類含有脂肪乳剤
US5383324A (en) 1993-04-23 1995-01-24 Baxter International Inc. Method for manufacturing and storing stable bicarbonate solutions
US6268338B1 (en) * 1993-04-30 2001-07-31 Merck & Co., Inc. Cyclohexapeptidyl amine compounds
US5541160A (en) 1994-04-04 1996-07-30 Merck & Co., Inc. Antifungal and anti-pneumocystis compounds, compositions containing such compounds, and methods of use
US5646111A (en) 1995-04-07 1997-07-08 Eli Lilly And Company Cyclic peptide antifungal Agents
US5629290A (en) 1995-05-26 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
US5786325A (en) 1995-05-26 1998-07-28 Eli Lilly And Company Cyclic peptide antifungal agents and methods of making and using
US5652213A (en) 1995-05-26 1997-07-29 Eli Lilly And Company Cyclic peptide antifungal agents
US5618787A (en) 1995-05-26 1997-04-08 Eli Lilly And Company Cyclic peptide antifungal agents
US5629289A (en) * 1995-07-25 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
WO1997027864A1 (fr) 1996-02-01 1997-08-07 Eli Lilly And Company Agents cycliques peptidiques antifongiques
US5693611A (en) 1996-02-01 1997-12-02 Eli Lilly And Company Cyclic peptide antifungal agents
US6245349B1 (en) 1996-02-23 2001-06-12 éLAN CORPORATION PLC Drug delivery compositions suitable for intravenous injection
US5696084A (en) * 1996-08-16 1997-12-09 Abbott Laboratories Amino-lipopetide antifungal agents
WO1999006062A1 (fr) 1997-08-04 1999-02-11 Eli Lilly And Company Agents antifongiques a base de peptide cyclique
US5972996A (en) * 1997-08-22 1999-10-26 Merck & Co., Inc. 4-cyano-4-deformylsordarin derivatives
EP0931834A3 (fr) 1997-12-23 2002-06-26 Eli Lilly And Company Domaine de liaison d'echinocandinl de la 1,3-beta-glucane synthase
US6323176B1 (en) 1998-02-25 2001-11-27 Eli Lilly And Company Cyclic peptide antifungal agents
ES2233070T3 (es) 1998-08-20 2005-06-01 ELI LILLY & COMPANY Sintesis de analogos peptidicos ciclicos modificados en el anillo.
WO2000012540A1 (fr) 1998-08-28 2000-03-09 Eli Lilly And Company Complexes boronates reversibles/peptides cycliques a 1,2-cis-diol
US6506726B1 (en) 1998-12-09 2003-01-14 Eli Lilly And Company Purification of Echinocandin cyclopeptide compounds
EP1140991A1 (fr) 1998-12-16 2001-10-10 Eli Lilly And Company Agents antifongiques de peptide cyclique
WO2000035945A1 (fr) 1998-12-16 2000-06-22 Eli Lilly And Company Agents antifongiques de peptide cyclique possedant un substituant sucre
EP1582204B1 (fr) * 1999-03-03 2013-09-25 Eli Lilly & Company Formulations pharmaceutiques d'échinocandine contenant des tensioactifs formant des micelles
IL145187A0 (en) 1999-03-03 2002-06-30 Lilly Co Eli Echinocandin/carbohydrate complexes
ATE338060T1 (de) 1999-03-03 2006-09-15 Lilly Co Eli Bildung und anionenaustausch von inneren kristallinen ammoniumsalzen des echinocandins b
CN1345230A (zh) 1999-03-03 2002-04-17 伊莱利利公司 口服ecb药物制剂和药物组合物的制备方法
US6258821B1 (en) 1999-04-26 2001-07-10 Medimmune Oncology, Inc. Compositions comprising trimetrexate and methods of their synthesis and use

Also Published As

Publication number Publication date
AU3393400A (en) 2000-09-21
EP1156784A1 (fr) 2001-11-28
HK1040369A1 (zh) 2002-06-07
CA2362482A1 (fr) 2000-09-08
WO2000051567A8 (fr) 2002-05-30
US6821951B2 (en) 2004-11-23
CN1345230A (zh) 2002-04-17
KR20010112302A (ko) 2001-12-20
AU771727B2 (en) 2004-04-01
WO2000051567A1 (fr) 2000-09-08
JP2002538097A (ja) 2002-11-12
BR0008713A (pt) 2001-12-26
ZA200108001B (en) 2003-06-25
US20020151474A1 (en) 2002-10-17

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