IL143802A0 - Imidazole derivatives and pharmaceutical compositions containing the same - Google Patents
Imidazole derivatives and pharmaceutical compositions containing the sameInfo
- Publication number
- IL143802A0 IL143802A0 IL14380299A IL14380299A IL143802A0 IL 143802 A0 IL143802 A0 IL 143802A0 IL 14380299 A IL14380299 A IL 14380299A IL 14380299 A IL14380299 A IL 14380299A IL 143802 A0 IL143802 A0 IL 143802A0
- Authority
- IL
- Israel
- Prior art keywords
- same
- pharmaceutical compositions
- compositions containing
- imidazole derivatives
- imidazole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP36736298 | 1998-12-24 | ||
| JP22883899 | 1999-08-12 | ||
| PCT/JP1999/007160 WO2000039097A1 (fr) | 1998-12-24 | 1999-12-20 | Composes d'imidazole et utilisation medicinale de ces composes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL143802A0 true IL143802A0 (en) | 2002-04-21 |
Family
ID=26528483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14380299A IL143802A0 (en) | 1998-12-24 | 1999-12-20 | Imidazole derivatives and pharmaceutical compositions containing the same |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7060721B1 (fr) |
| EP (1) | EP1142879B1 (fr) |
| KR (1) | KR20010094731A (fr) |
| CN (1) | CN1170822C (fr) |
| AR (1) | AR022019A1 (fr) |
| AT (1) | ATE375332T1 (fr) |
| AU (1) | AU758325C (fr) |
| BR (1) | BR9917112A (fr) |
| CA (1) | CA2356838A1 (fr) |
| CZ (1) | CZ20012338A3 (fr) |
| DE (1) | DE69937307T2 (fr) |
| ES (1) | ES2292262T3 (fr) |
| HK (1) | HK1043791A1 (fr) |
| HU (1) | HUP0104657A3 (fr) |
| IL (1) | IL143802A0 (fr) |
| RU (1) | RU2238937C2 (fr) |
| TR (1) | TR200101865T2 (fr) |
| TW (1) | TWI239330B (fr) |
| WO (1) | WO2000039097A1 (fr) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0009037D0 (en) * | 2000-04-13 | 2000-05-31 | Novartis Ag | Organic compounds |
| US20030181461A1 (en) * | 2002-01-25 | 2003-09-25 | Lautt Wilfred Wayne | Use of phosphodiesterase antagonists to treat insulin resistance |
| AU2012200214B2 (en) * | 2004-05-14 | 2013-10-24 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| ES2249992B1 (es) * | 2004-09-13 | 2007-03-01 | Ferrer Internacional, S.A. | Un procedimiento para fabricar compuestos enantiomericos del imidazol. |
| US20080009530A1 (en) * | 2005-08-10 | 2008-01-10 | Hidenori Abe | Therapeutic Agent for Diabetes |
| JP2009534366A (ja) * | 2006-04-21 | 2009-09-24 | アストラゼネカ アクチボラグ | Ｅｄｇ−１拮抗剤として使用するためのイミダゾール誘導体 |
| TW200838501A (en) | 2007-02-02 | 2008-10-01 | Theravance Inc | Dual-acting antihypertensive agents |
| WO2008099794A1 (fr) * | 2007-02-09 | 2008-08-21 | Takeda Pharmaceutical Company Limited | Composés à cycles fusionnés utiles en tant qu'agonistes partiels de ppar-gamma |
| TWI448284B (zh) | 2007-04-24 | 2014-08-11 | Theravance Inc | 雙效抗高血壓劑 |
| TWI406850B (zh) * | 2007-06-05 | 2013-09-01 | Theravance Inc | 雙效苯并咪唑抗高血壓劑 |
| KR100868898B1 (ko) * | 2007-07-30 | 2008-11-14 | 한국기계연구원 | 적층형 ｐｚｔ를 이용한 압전펌프 |
| US7834041B2 (en) | 2007-09-07 | 2010-11-16 | Theravance, Inc. | Dual-acting antihypertensive agents |
| US8212052B2 (en) | 2007-12-11 | 2012-07-03 | Theravance, Inc. | Dual-acting benzoimidazole antihypertensive agents |
| JP2011518884A (ja) | 2008-04-29 | 2011-06-30 | セラヴァンス， インコーポレーテッド | 二重活性抗高血圧剤 |
| US8124636B2 (en) * | 2008-04-30 | 2012-02-28 | Hoffmann-La Roche Inc. | Imidazolidinone derivatives as 11B-HSD1 inhibitors |
| EP2334651A2 (fr) | 2008-07-24 | 2011-06-22 | Theravance, Inc. | Agents anti-hypertensifs à double action |
| MY157304A (en) * | 2009-05-15 | 2016-05-31 | Sanofi Sa | Process for the preparation of a compound useful as an inhibator of tafia |
| US7956054B2 (en) | 2009-07-07 | 2011-06-07 | Theravance, Inc. | Dual-acting pyrazole antihypertensive agents |
| WO2011011232A1 (fr) | 2009-07-22 | 2011-01-27 | Theravance, Inc. | Agents antihypertenseurs à double action à base d'oxazole |
| JP2013517295A (ja) | 2010-01-19 | 2013-05-16 | セラヴァンス， インコーポレーテッド | 二重に作用するチオフェン、ピロール、チアゾールおよびフラン抗高血圧症薬 |
| EP3848361A4 (fr) | 2018-09-04 | 2022-06-15 | Chugai Seiyaku Kabushiki Kaisha | Procédé de production de composé tétracyclique |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5215994A (en) | 1990-09-25 | 1993-06-01 | Fujisawa Pharmaceutical Co., Ltd. | Angiotenin II antagonizing heterocyclic derivatives |
| TW235963B (fr) | 1992-01-16 | 1994-12-11 | Shionogi & Co | |
| US6166219A (en) | 1995-12-28 | 2000-12-26 | Fujisawa Pharmaceutical Co., Ltd. | Benzimidazole derivatives |
| CN1268942A (zh) | 1997-06-27 | 2000-10-04 | 藤泽药品工业株式会社 | 磺酰胺化合物及其药物用途 |
| DE69826286T2 (de) | 1997-06-27 | 2005-11-24 | Fujisawa Pharmaceutical Co., Ltd. | Derivate mit einem aromatischen ring |
-
1999
- 1999-12-20 DE DE69937307T patent/DE69937307T2/de not_active Expired - Fee Related
- 1999-12-20 CA CA002356838A patent/CA2356838A1/fr not_active Abandoned
- 1999-12-20 IL IL14380299A patent/IL143802A0/xx unknown
- 1999-12-20 RU RU2001120723A patent/RU2238937C2/ru not_active IP Right Cessation
- 1999-12-20 WO PCT/JP1999/007160 patent/WO2000039097A1/fr not_active Application Discontinuation
- 1999-12-20 AT AT99959929T patent/ATE375332T1/de not_active IP Right Cessation
- 1999-12-20 BR BR9917112-0A patent/BR9917112A/pt not_active IP Right Cessation
- 1999-12-20 HU HU0104657A patent/HUP0104657A3/hu unknown
- 1999-12-20 AU AU16905/00A patent/AU758325C/en not_active Ceased
- 1999-12-20 EP EP99959929A patent/EP1142879B1/fr not_active Expired - Lifetime
- 1999-12-20 ES ES99959929T patent/ES2292262T3/es not_active Expired - Lifetime
- 1999-12-20 US US09/869,135 patent/US7060721B1/en not_active Expired - Fee Related
- 1999-12-20 CZ CZ20012338A patent/CZ20012338A3/cs unknown
- 1999-12-20 KR KR1020017008097A patent/KR20010094731A/ko not_active Application Discontinuation
- 1999-12-20 CN CNB998163600A patent/CN1170822C/zh not_active Expired - Fee Related
- 1999-12-20 TR TR2001/01865T patent/TR200101865T2/xx unknown
- 1999-12-22 TW TW088122630A patent/TWI239330B/zh not_active IP Right Cessation
- 1999-12-23 AR ARP990106750A patent/AR022019A1/es unknown
-
2002
- 2002-07-18 HK HK02105326A patent/HK1043791A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CZ20012338A3 (cs) | 2001-12-12 |
| TR200101865T2 (tr) | 2001-12-21 |
| HUP0104657A2 (hu) | 2002-05-29 |
| DE69937307D1 (de) | 2007-11-22 |
| AU758325B2 (en) | 2003-03-20 |
| CA2356838A1 (fr) | 2000-07-06 |
| ES2292262T3 (es) | 2008-03-01 |
| US7060721B1 (en) | 2006-06-13 |
| CN1170822C (zh) | 2004-10-13 |
| TWI239330B (en) | 2005-09-11 |
| BR9917112A (pt) | 2002-01-29 |
| HUP0104657A3 (en) | 2002-07-29 |
| AU758325C (en) | 2004-10-07 |
| RU2238937C2 (ru) | 2004-10-27 |
| EP1142879B1 (fr) | 2007-10-10 |
| ATE375332T1 (de) | 2007-10-15 |
| DE69937307T2 (de) | 2008-02-07 |
| AU1690500A (en) | 2000-07-31 |
| AR022019A1 (es) | 2002-09-04 |
| EP1142879A4 (fr) | 2002-02-06 |
| CN1335837A (zh) | 2002-02-13 |
| WO2000039097A1 (fr) | 2000-07-06 |
| HK1043791A1 (en) | 2002-09-27 |
| EP1142879A1 (fr) | 2001-10-10 |
| KR20010094731A (ko) | 2001-11-01 |
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