IL143176A - Method for identifying cytosine methylation patterns in genomic dna - Google Patents

Method for identifying cytosine methylation patterns in genomic dna

Info

Publication number
IL143176A
IL143176A IL14317699A IL14317699A IL143176A IL 143176 A IL143176 A IL 143176A IL 14317699 A IL14317699 A IL 14317699A IL 14317699 A IL14317699 A IL 14317699A IL 143176 A IL143176 A IL 143176A
Authority
IL
Israel
Prior art keywords
genomic dna
methylation patterns
cytosine methylation
identifying
identifying cytosine
Prior art date
Application number
IL14317699A
Other languages
English (en)
Other versions
IL143176A0 (en
Original Assignee
Epigenomics Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epigenomics Ag filed Critical Epigenomics Ag
Publication of IL143176A0 publication Critical patent/IL143176A0/xx
Publication of IL143176A publication Critical patent/IL143176A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
IL14317699A 1998-11-19 1999-11-19 Method for identifying cytosine methylation patterns in genomic dna IL143176A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19853398A DE19853398C1 (de) 1998-11-19 1998-11-19 Verfahren zur Identifikation von Cytosin-Methylierungsmustern in genomischer DNA
PCT/DE1999/003747 WO2000031294A2 (de) 1998-11-19 1999-11-19 Verfahren zur identifikation von cytosin-methylierungsmustern in genomischer dna

Publications (2)

Publication Number Publication Date
IL143176A0 IL143176A0 (en) 2002-04-21
IL143176A true IL143176A (en) 2005-05-17

Family

ID=7888355

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14317699A IL143176A (en) 1998-11-19 1999-11-19 Method for identifying cytosine methylation patterns in genomic dna

Country Status (9)

Country Link
EP (1) EP1135526A2 (de)
JP (1) JP2002530118A (de)
AU (1) AU757473B2 (de)
CA (1) CA2351143A1 (de)
DE (1) DE19853398C1 (de)
IL (1) IL143176A (de)
IS (1) IS5916A (de)
NZ (1) NZ511638A (de)
WO (1) WO2000031294A2 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9929720D0 (en) * 1999-12-17 2000-02-09 Zeneca Ltd Diagnostic method
DE10032529A1 (de) * 2000-06-30 2002-02-07 Epigenomics Ag Diagnose von bedeutenden genetischen Parametern innerhalb des Major Histocompatibility Complex (MHC)
DE10019058A1 (de) * 2000-04-06 2001-12-20 Epigenomics Ag Detektion von Variationen des DNA-Methylierungsprofils
AU2001255870B2 (en) * 2000-04-28 2006-07-13 Sangamo Biosciences, Inc. Databases of regulatory sequences; methods of making and using same
DE10029915B4 (de) * 2000-06-19 2005-06-16 Epigenomics Ag Verfahren zum Nachweis von Cytosin-Methylierungen
IL154663A0 (en) * 2000-09-01 2003-09-17 Epigenomics Ag Method for determining the degree of methylation of defined cytosines in genomic dna in the sequence context 5'-cpg-3'
DE10050942B4 (de) * 2000-10-10 2005-11-17 Epigenomics Ag Verfahren zum Nachweis von Cytosin-Methylierungen
GB0025913D0 (en) 2000-10-23 2000-12-06 Guldberg Per Materials and methods relating to nucleic acid amplification and profiling
ATE445023T1 (de) * 2000-10-23 2009-10-15 Cancer Rec Tech Ltd Auf nukleinsäurenamplifizierung basierendes verfahren zur bestimmung von methylierungsprofil und reagenzien dafür
DE10061348C2 (de) * 2000-12-06 2002-10-24 Epigenomics Ag Verfahren zur Quantifizierung von Cytosin-Methylierungen in komplex amplifizierter genomischer DNA
DE10132212B4 (de) * 2001-06-27 2005-11-24 Epigenomics Ag Verfahren zum Nachweis von Cytosin-Methylierung durch vergleichende Analyse der Einzelstränge von Amplifikaten
WO2003008642A2 (en) 2001-07-15 2003-01-30 Keck Graduate Institute Amplification of nucleic acid fragments using nicking agents
JP2003144172A (ja) * 2001-11-16 2003-05-20 Nisshinbo Ind Inc メチル化検出用オリゴヌクレオチド固定化基板
WO2003064701A2 (en) * 2002-01-30 2003-08-07 Epigenomics Ag Method for the analysis of cytosine methylation patterns
DE10204566A1 (de) * 2002-02-04 2003-08-14 Nanogen Recognomics Gmbh Verfahren zur Bestimmung des Methylierungsmusters von DNA
DE102004002257B4 (de) * 2004-01-09 2006-11-09 Epigenomics Ag Verfahren zur Untersuchung von Cytosin-Methylierungen in DNA mit Hilfe von DNA-Reparaturenzymen
JP5167485B2 (ja) * 2005-06-08 2013-03-21 国立大学法人京都大学 メチルシトシンの簡便検出法
JP2013514758A (ja) * 2008-12-23 2013-05-02 ニユー・イングランド・バイオレイブス・インコーポレイテツド 修飾ｄｎａを切断するための組成物、方法および関連する使用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD293139A5 (de) * 1989-06-29 1991-08-22 Humboldt-Universitaet Zu Berlin,Direktorat Fuer Forschung,De Verfahren zur charakterisierung bestimmter dna-sequenzen
DE69218776T2 (de) * 1991-07-19 1997-11-27 Upstate Biotech Inc Verfahren zum nachweis von mutationen
US5750335A (en) * 1992-04-24 1998-05-12 Massachusetts Institute Of Technology Screening for genetic variation
US5824471A (en) * 1995-06-05 1998-10-20 Brigham And Women's Hospital Detection of mismatches by cleavage of nucleic acid heteroduplexes
AU2069597A (en) * 1996-03-04 1997-09-22 Genetrace Systems, Inc. Methods of screening nucleic acids using mass spectrometry
US5871917A (en) * 1996-05-31 1999-02-16 North Shore University Hospital Research Corp. Identification of differentially methylated and mutated nucleic acids
US6017704A (en) * 1996-06-03 2000-01-25 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
DE19754482A1 (de) * 1997-11-27 1999-07-01 Epigenomics Gmbh Verfahren zur Herstellung komplexer DNA-Methylierungs-Fingerabdrücke

Also Published As

Publication number Publication date
IS5916A (is) 2001-04-10
DE19853398C1 (de) 2000-03-16
WO2000031294A2 (de) 2000-06-02
AU757473B2 (en) 2003-02-20
JP2002530118A (ja) 2002-09-17
IL143176A0 (en) 2002-04-21
AU1856500A (en) 2000-06-13
EP1135526A2 (de) 2001-09-26
WO2000031294A3 (de) 2000-10-19
CA2351143A1 (en) 2000-06-02
NZ511638A (en) 2003-11-28

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