IL143176A0 - Method for identifying cytosine methylation patterns in genomic dna - Google Patents

Method for identifying cytosine methylation patterns in genomic dna

Info

Publication number
IL143176A0
IL143176A0 IL14317699A IL14317699A IL143176A0 IL 143176 A0 IL143176 A0 IL 143176A0 IL 14317699 A IL14317699 A IL 14317699A IL 14317699 A IL14317699 A IL 14317699A IL 143176 A0 IL143176 A0 IL 143176A0
Authority
IL
Israel
Prior art keywords
genomic dna
methylation patterns
cytosine methylation
identifying
identifying cytosine
Prior art date
Application number
IL14317699A
Other versions
IL143176A (en
Original Assignee
Epigenomics Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epigenomics Ag filed Critical Epigenomics Ag
Publication of IL143176A0 publication Critical patent/IL143176A0/en
Publication of IL143176A publication Critical patent/IL143176A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IL14317699A 1998-11-19 1999-11-19 Method for identifying cytosine methylation patterns in genomic dna IL143176A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19853398A DE19853398C1 (en) 1998-11-19 1998-11-19 Identification of 5-methylcytosine positions in genomic DNA by chemical modification, amplification and heteroduplex formation
PCT/DE1999/003747 WO2000031294A2 (en) 1998-11-19 1999-11-19 Method for identifying cytosine methylation patterns in genomic dna

Publications (2)

Publication Number Publication Date
IL143176A0 true IL143176A0 (en) 2002-04-21
IL143176A IL143176A (en) 2005-05-17

Family

ID=7888355

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14317699A IL143176A (en) 1998-11-19 1999-11-19 Method for identifying cytosine methylation patterns in genomic dna

Country Status (9)

Country Link
EP (1) EP1135526A2 (en)
JP (1) JP2002530118A (en)
AU (1) AU757473B2 (en)
CA (1) CA2351143A1 (en)
DE (1) DE19853398C1 (en)
IL (1) IL143176A (en)
IS (1) IS5916A (en)
NZ (1) NZ511638A (en)
WO (1) WO2000031294A2 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9929720D0 (en) * 1999-12-17 2000-02-09 Zeneca Ltd Diagnostic method
DE10019058A1 (en) * 2000-04-06 2001-12-20 Epigenomics Ag Designing primers and probes for analyzing diseases associated with cytosine methylation state e.g. arthritis, cancer, aging, arteriosclerosis comprising fragments of chemically modified genes associated with cell cycle
DE10032529A1 (en) * 2000-06-30 2002-02-07 Epigenomics Ag Diagnosis of major genetic parameters within the Major Histocompatibility Complex (MHC)
US7217509B2 (en) 2000-04-28 2007-05-15 Sangamo Biosciences, Inc. Databases of regulatory sequences; methods of making and using same
DE10029915B4 (en) 2000-06-19 2005-06-16 Epigenomics Ag Method for the detection of cytosine methylations
US20040234960A1 (en) * 2000-09-01 2004-11-25 Alexander Olek Method for determining the degree of methylation of defined cytosines in genomic dna in the sequence context 5'-cpg-3'
DE10050942B4 (en) * 2000-10-10 2005-11-17 Epigenomics Ag Method for the detection of cytosine methylations
CA2425904A1 (en) * 2000-10-23 2002-05-02 Cancer Research Technology Limited Materials and methods relating to nucleic acid amplification and profiling
GB0025913D0 (en) 2000-10-23 2000-12-06 Guldberg Per Materials and methods relating to nucleic acid amplification and profiling
DE10061348C2 (en) * 2000-12-06 2002-10-24 Epigenomics Ag Method for the quantification of cytosine methylations in complex amplified genomic DNA
DE10132212B4 (en) * 2001-06-27 2005-11-24 Epigenomics Ag Method for the detection of cytosine methylation by comparative analysis of the single strands of amplicons
MXPA04000432A (en) 2001-07-15 2004-10-27 Keck Graduate Inst Amplification of nucleic acid fragments using nicking agents.
JP2003144172A (en) * 2001-11-16 2003-05-20 Nisshinbo Ind Inc Oligonucleotide-immobilized board for detecting methylation
US20030215842A1 (en) * 2002-01-30 2003-11-20 Epigenomics Ag Method for the analysis of cytosine methylation patterns
DE10204566A1 (en) * 2002-02-04 2003-08-14 Nanogen Recognomics Gmbh Method for determining the methylation pattern of DNA
DE102004002257B4 (en) * 2004-01-09 2006-11-09 Epigenomics Ag Method for studying cytosine methylations in DNA using DNA repair enzymes
JP5167485B2 (en) * 2005-06-08 2013-03-21 国立大学法人京都大学 Simple detection method for methylcytosine
EP2376632B1 (en) * 2008-12-23 2016-11-02 New England Biolabs, Inc. Compositions, methods and related uses for cleaving modified dna

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD293139A5 (en) * 1989-06-29 1991-08-22 Humboldt-Universitaet Zu Berlin,Direktorat Fuer Forschung,De METHOD FOR CHARACTERIZING CERTAIN DNA SEQUENCES
EP0596028B1 (en) * 1991-07-19 1997-04-02 Upstate Biotechnology, Inc. Method for detection of mutations
WO1993022457A1 (en) * 1992-04-24 1993-11-11 Massachusetts Institute Of Technology Screening for genetic variation
US5824471A (en) * 1995-06-05 1998-10-20 Brigham And Women's Hospital Detection of mismatches by cleavage of nucleic acid heteroduplexes
CA2248084A1 (en) * 1996-03-04 1997-09-12 Genetrace Systems, Inc. Methods of screening nucleic acids using mass spectrometry
US5871917A (en) * 1996-05-31 1999-02-16 North Shore University Hospital Research Corp. Identification of differentially methylated and mutated nucleic acids
US6017704A (en) * 1996-06-03 2000-01-25 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
DE19754482A1 (en) * 1997-11-27 1999-07-01 Epigenomics Gmbh Process for making complex DNA methylation fingerprints

Also Published As

Publication number Publication date
WO2000031294A2 (en) 2000-06-02
CA2351143A1 (en) 2000-06-02
AU1856500A (en) 2000-06-13
AU757473B2 (en) 2003-02-20
WO2000031294A3 (en) 2000-10-19
IL143176A (en) 2005-05-17
DE19853398C1 (en) 2000-03-16
IS5916A (en) 2001-04-10
NZ511638A (en) 2003-11-28
EP1135526A2 (en) 2001-09-26
JP2002530118A (en) 2002-09-17

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