AU2001242280A1 - Method for detecting cytosine methylation in dna samples - Google Patents
Method for detecting cytosine methylation in dna samplesInfo
- Publication number
- AU2001242280A1 AU2001242280A1 AU2001242280A AU2001242280A AU2001242280A1 AU 2001242280 A1 AU2001242280 A1 AU 2001242280A1 AU 2001242280 A AU2001242280 A AU 2001242280A AU 2001242280 A AU2001242280 A AU 2001242280A AU 2001242280 A1 AU2001242280 A1 AU 2001242280A1
- Authority
- AU
- Australia
- Prior art keywords
- dna samples
- cytosine methylation
- detecting cytosine
- detecting
- methylation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000030933 DNA methylation on cytosine Effects 0.000 title 1
- 229920003013 deoxyribonucleic acid Polymers 0.000 title 1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10010280A DE10010280B4 (en) | 2000-02-25 | 2000-02-25 | Method for the detection of cytosine methylation in DNA samples |
DE10010280.8 | 2000-02-25 | ||
PCT/DE2001/000750 WO2001062064A2 (en) | 2000-02-25 | 2001-02-23 | Method for detecting cytosine methylation in dna samples |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2007202468A Division AU2007202468A1 (en) | 1999-06-01 | 2007-05-30 | Method for detecting cytosine methylation in DNA samples |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2001242280A1 true AU2001242280A1 (en) | 2001-11-15 |
AU2001242280B2 AU2001242280B2 (en) | 2007-03-01 |
Family
ID=7633311
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001242280A Ceased AU2001242280B2 (en) | 2000-02-25 | 2001-02-23 | Method for detecting cytosine methylation in dna samples |
AU4228001A Pending AU4228001A (en) | 2000-02-25 | 2001-02-23 | Method for detecting cytosine methylation in dna samples |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU4228001A Pending AU4228001A (en) | 2000-02-25 | 2001-02-23 | Method for detecting cytosine methylation in dna samples |
Country Status (9)
Country | Link |
---|---|
US (1) | US7524629B2 (en) |
EP (1) | EP1261741B1 (en) |
JP (1) | JP4498657B2 (en) |
AT (1) | ATE395434T1 (en) |
AU (2) | AU2001242280B2 (en) |
CA (1) | CA2399281C (en) |
DE (2) | DE10010280B4 (en) |
ES (1) | ES2307597T3 (en) |
WO (1) | WO2001062064A2 (en) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7955794B2 (en) | 2000-09-21 | 2011-06-07 | Illumina, Inc. | Multiplex nucleic acid reactions |
US7582420B2 (en) | 2001-07-12 | 2009-09-01 | Illumina, Inc. | Multiplex nucleic acid reactions |
US8076063B2 (en) | 2000-02-07 | 2011-12-13 | Illumina, Inc. | Multiplexed methylation detection methods |
DE10010282B4 (en) * | 2000-02-25 | 2006-11-16 | Epigenomics Ag | Method for the detection of cytosine methylation in DNA samples |
DE10010281B4 (en) * | 2000-02-25 | 2005-03-10 | Epigenomics Ag | Ligase / polymerase method for the detection of cytosine methylation in DNA samples |
DE10151055B4 (en) | 2001-10-05 | 2005-05-25 | Epigenomics Ag | Method for detecting cytosine methylation in CpG islands |
US20110151438A9 (en) | 2001-11-19 | 2011-06-23 | Affymetrix, Inc. | Methods of Analysis of Methylation |
DE10160983B4 (en) * | 2001-12-05 | 2004-12-09 | Epigenomics Ag | Method and integrated device for the detection of cytosine methylation |
US6960436B2 (en) * | 2002-02-06 | 2005-11-01 | Epigenomics Ag | Quantitative methylation detection in DNA samples |
CA2442438C (en) | 2002-10-04 | 2012-06-19 | Nisshinbo Industries, Inc. | Oligonucleotide-immobilized substrate for detecting methylation |
US20060094016A1 (en) * | 2002-12-02 | 2006-05-04 | Niall Gormley | Determination of methylation of nucleic acid sequences |
US20050009059A1 (en) * | 2003-05-07 | 2005-01-13 | Affymetrix, Inc. | Analysis of methylation status using oligonucleotide arrays |
US20060134650A1 (en) * | 2004-12-21 | 2006-06-22 | Illumina, Inc. | Methylation-sensitive restriction enzyme endonuclease method of whole genome methylation analysis |
ES2647483T3 (en) | 2005-04-01 | 2017-12-21 | Epigenomics Ag | Improved bisulfite conversion of DNA |
SI1871912T1 (en) | 2005-04-15 | 2012-06-29 | Epigenomics Ag | Method for determining DNA methylation in blood or urine samples |
US20060292585A1 (en) * | 2005-06-24 | 2006-12-28 | Affymetrix, Inc. | Analysis of methylation using nucleic acid arrays |
EP1969139A1 (en) | 2005-11-17 | 2008-09-17 | Epigenomics AG | Method for the determination of the dna methylation level of a cpg position in identical cells within a tissue sample |
US7820385B2 (en) * | 2006-03-22 | 2010-10-26 | The United States Of America As Represented By The Department Of Health And Human Services, Centers For Disease Control And Prevention | Method for retaining methylation pattern in globally amplified DNA |
US7901882B2 (en) | 2006-03-31 | 2011-03-08 | Affymetrix, Inc. | Analysis of methylation using nucleic acid arrays |
US8084734B2 (en) * | 2006-05-26 | 2011-12-27 | The George Washington University | Laser desorption ionization and peptide sequencing on laser induced silicon microcolumn arrays |
WO2008096146A1 (en) | 2007-02-07 | 2008-08-14 | Solexa Limited | Preparation of templates for methylation analysis |
US20080213870A1 (en) * | 2007-03-01 | 2008-09-04 | Sean Wuxiong Cao | Methods for obtaining modified DNA from a biological specimen |
DK2479289T3 (en) | 2007-06-08 | 2016-05-02 | Epigenomics Ag | Method for methylation analysis |
EP2586876B1 (en) * | 2008-08-15 | 2014-10-08 | Cascade Biosystems, Inc. | Detecting nucleic acid |
WO2010048337A2 (en) | 2008-10-22 | 2010-04-29 | Illumina, Inc. | Preservation of information related to genomic dna methylation |
US8110796B2 (en) | 2009-01-17 | 2012-02-07 | The George Washington University | Nanophotonic production, modulation and switching of ions by silicon microcolumn arrays |
US9490113B2 (en) * | 2009-04-07 | 2016-11-08 | The George Washington University | Tailored nanopost arrays (NAPA) for laser desorption ionization in mass spectrometry |
US9624530B2 (en) | 2009-08-03 | 2017-04-18 | Epigenomics Ag | Methods for preservation of genomic DNA sequence complexity |
US20110104695A1 (en) | 2009-11-05 | 2011-05-05 | Epigenomics Ag | Methods of predicting therapeutic efficacy of cancer therapy |
WO2011100747A1 (en) | 2010-02-15 | 2011-08-18 | Cascade Biosystems, Inc. | Methods and materials for detecting contaminated food products |
WO2011100749A2 (en) | 2010-02-15 | 2011-08-18 | Cascade Biosystems, Inc. | Methods and materials for detecting viral or microbial infections |
EP2536847B1 (en) * | 2010-02-15 | 2018-08-08 | Cascade Biosystems, Inc. | Methods and materials for assessing rna expression |
EP2536848B1 (en) | 2010-02-15 | 2017-07-19 | Cascade Biosystems, Inc. | Methods and materials for detecting genetic or epigenetic elements |
WO2013084075A2 (en) * | 2011-12-06 | 2013-06-13 | Mdxhealth Sa | Methods of detecting mutations and epigenetic changes |
US10640808B2 (en) | 2013-03-13 | 2020-05-05 | Abbott Molecular Inc. | Systems and methods for isolating nucleic acids |
CN105378107A (en) | 2013-03-14 | 2016-03-02 | 雅培分子公司 | Multiplex methylation-specific amplification systems and methods |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6013431A (en) * | 1990-02-16 | 2000-01-11 | Molecular Tool, Inc. | Method for determining specific nucleotide variations by primer extension in the presence of mixture of labeled nucleotides and terminators |
US5605798A (en) * | 1993-01-07 | 1997-02-25 | Sequenom, Inc. | DNA diagnostic based on mass spectrometry |
SE501439C2 (en) | 1993-06-22 | 1995-02-13 | Pharmacia Lkb Biotech | Method and apparatus for analyzing polynucleotide sequences |
DE19515552A1 (en) * | 1995-04-27 | 1996-10-31 | Europ Lab Molekularbiolog | Simultaneous sequencing of nucleic acids |
US5728526A (en) * | 1995-06-07 | 1998-03-17 | Oncor, Inc. | Method for analyzing a nucleotide sequence |
ES2563643T3 (en) * | 1997-04-01 | 2016-03-15 | Illumina Cambridge Limited | Nucleic acid sequencing method |
WO1998056952A1 (en) | 1997-06-09 | 1998-12-17 | University Of Southern California | A cancer diagnostic method based upon dna methylation differences |
DE19754482A1 (en) * | 1997-11-27 | 1999-07-01 | Epigenomics Gmbh | Process for making complex DNA methylation fingerprints |
AUPP312998A0 (en) | 1998-04-23 | 1998-05-14 | Commonwealth Scientific And Industrial Research Organisation | Diagnostic assay |
WO1999058721A1 (en) * | 1998-05-12 | 1999-11-18 | Whitehead Institute For Biomedical Research | Multiplex dna amplification using chimeric primers |
WO1999067414A1 (en) * | 1998-06-24 | 1999-12-29 | Glaxo Group Limited | Nucleotide detection method |
DE10010281B4 (en) * | 2000-02-25 | 2005-03-10 | Epigenomics Ag | Ligase / polymerase method for the detection of cytosine methylation in DNA samples |
DE10010282B4 (en) * | 2000-02-25 | 2006-11-16 | Epigenomics Ag | Method for the detection of cytosine methylation in DNA samples |
-
2000
- 2000-02-25 DE DE10010280A patent/DE10010280B4/en not_active Expired - Fee Related
-
2001
- 2001-02-23 CA CA2399281A patent/CA2399281C/en not_active Expired - Fee Related
- 2001-02-23 ES ES01915054T patent/ES2307597T3/en not_active Expired - Lifetime
- 2001-02-23 US US10/220,090 patent/US7524629B2/en not_active Expired - Fee Related
- 2001-02-23 JP JP2001561142A patent/JP4498657B2/en not_active Expired - Fee Related
- 2001-02-23 DE DE50113970T patent/DE50113970D1/en not_active Expired - Lifetime
- 2001-02-23 EP EP01915054A patent/EP1261741B1/en not_active Expired - Lifetime
- 2001-02-23 AU AU2001242280A patent/AU2001242280B2/en not_active Ceased
- 2001-02-23 WO PCT/DE2001/000750 patent/WO2001062064A2/en active IP Right Grant
- 2001-02-23 AU AU4228001A patent/AU4228001A/en active Pending
- 2001-02-23 AT AT01915054T patent/ATE395434T1/en not_active IP Right Cessation
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