AU2001242279A1 - Ligase/polymerase method for detecting cytosine methylation in DNA samples - Google Patents

Ligase/polymerase method for detecting cytosine methylation in DNA samples

Info

Publication number
AU2001242279A1
AU2001242279A1 AU2001242279A AU2001242279A AU2001242279A1 AU 2001242279 A1 AU2001242279 A1 AU 2001242279A1 AU 2001242279 A AU2001242279 A AU 2001242279A AU 2001242279 A AU2001242279 A AU 2001242279A AU 2001242279 A1 AU2001242279 A1 AU 2001242279A1
Authority
AU
Australia
Prior art keywords
ligase
dna samples
cytosine methylation
detecting cytosine
polymerase method
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2001242279A
Other versions
AU2001242279B2 (en
Inventor
Kurt Berlin
Alexander Olek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Epigenomics AG
Original Assignee
Epigenomics AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10010281A external-priority patent/DE10010281B4/en
Application filed by Epigenomics AG filed Critical Epigenomics AG
Publication of AU2001242279A1 publication Critical patent/AU2001242279A1/en
Application granted granted Critical
Publication of AU2001242279B2 publication Critical patent/AU2001242279B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

AU2001242279A 2000-02-25 2001-02-23 Ligase/polymerase method for detecting cytosine methylation in DNA samples Ceased AU2001242279B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10010281A DE10010281B4 (en) 2000-02-25 2000-02-25 Ligase / polymerase method for the detection of cytosine methylation in DNA samples
DE10010281.6 2000-02-25
PCT/DE2001/000749 WO2001062961A1 (en) 2000-02-25 2001-02-23 Ligase/polymerase method for detecting cytosine methylation in dna samples

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2006236059A Division AU2006236059A1 (en) 2000-02-25 2006-11-17 Ligase/polymerase method for detecting cytosine methylation in DNA samples

Publications (2)

Publication Number Publication Date
AU2001242279A1 true AU2001242279A1 (en) 2001-11-15
AU2001242279B2 AU2001242279B2 (en) 2006-10-26

Family

ID=7633312

Family Applications (3)

Application Number Title Priority Date Filing Date
AU4227901A Pending AU4227901A (en) 2000-02-25 2001-02-23 Ligase/polymerase method for detecting cytosine methylation in dna samples
AU2001242279A Ceased AU2001242279B2 (en) 2000-02-25 2001-02-23 Ligase/polymerase method for detecting cytosine methylation in DNA samples
AU2006236059A Abandoned AU2006236059A1 (en) 2000-02-25 2006-11-17 Ligase/polymerase method for detecting cytosine methylation in DNA samples

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AU4227901A Pending AU4227901A (en) 2000-02-25 2001-02-23 Ligase/polymerase method for detecting cytosine methylation in dna samples

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2006236059A Abandoned AU2006236059A1 (en) 2000-02-25 2006-11-17 Ligase/polymerase method for detecting cytosine methylation in DNA samples

Country Status (7)

Country Link
US (1) US7405040B2 (en)
EP (1) EP1261740A1 (en)
JP (1) JP2003523752A (en)
AU (3) AU4227901A (en)
CA (1) CA2401198A1 (en)
DE (1) DE10010281B4 (en)
WO (1) WO2001062961A1 (en)

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US8076063B2 (en) 2000-02-07 2011-12-13 Illumina, Inc. Multiplexed methylation detection methods
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
DE10010280B4 (en) * 2000-02-25 2006-08-10 Epigenomics Ag Method for the detection of cytosine methylation in DNA samples
DE10154318A1 (en) * 2001-10-26 2003-05-15 Epigenomics Ag Method for analyzing genomic methylation patterns
US20110151438A9 (en) * 2001-11-19 2011-06-23 Affymetrix, Inc. Methods of Analysis of Methylation
EP1860200A1 (en) * 2001-12-03 2007-11-28 Illumina, Inc. Multiplexed methylation detection methods
DE10201138B4 (en) * 2002-01-08 2005-03-10 Epigenomics Ag Method for the detection of cytosine methylation patterns by exponential ligation of hybridized probe oligonucleotides (MLA)
US20040101843A1 (en) * 2002-11-22 2004-05-27 Gerald Zon Detection of methylated DNA sites
ATE462017T1 (en) * 2002-12-02 2010-04-15 Illumina Cambridge Ltd DETERMINATION OF METHYLATION OF NUCLEIC ACID SEQUENCES
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US7288373B2 (en) * 2003-05-02 2007-10-30 Human Genetic Signatures Pty Ltd. Treatment of methylated nucleic acid
US20050009059A1 (en) * 2003-05-07 2005-01-13 Affymetrix, Inc. Analysis of methylation status using oligonucleotide arrays
US7799525B2 (en) * 2003-06-17 2010-09-21 Human Genetic Signatures Pty Ltd. Methods for genome amplification
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US8168777B2 (en) 2004-04-29 2012-05-01 Human Genetic Signatures Pty. Ltd. Bisulphite reagent treatment of nucleic acid
US7364855B2 (en) * 2004-04-30 2008-04-29 Applera Corporation Methods and kits for methylation detection
US20060234252A1 (en) * 2004-07-02 2006-10-19 Applera Corporation Methods and kits for methylation detection
CN101056883B (en) * 2004-09-10 2012-10-10 人类遗传标记控股有限公司 Amplification blocker for intercalating nucleic acid (ina) containing intercalating pseudo nucleic acid (IPN)
KR101293713B1 (en) * 2004-12-03 2013-08-12 휴먼 제네틱 시그너처스 피티와이 엘티디 Methods for simplifying microbial nucleic acids by chemical modification of cytosines
US20060134650A1 (en) * 2004-12-21 2006-06-22 Illumina, Inc. Methylation-sensitive restriction enzyme endonuclease method of whole genome methylation analysis
CN101142323A (en) * 2004-12-23 2008-03-12 人类遗传标记控股有限公司 Detection of human papilloma virus
PT1871912E (en) 2005-04-15 2012-05-25 Epigenomics Ag Method for determining dna methylation in blood or urine samples
CA2609218C (en) * 2005-05-26 2016-10-11 Human Genetic Signatures Pty Ltd Isothermal strand displacement amplification using primers containing a non-regular base
US20060292585A1 (en) * 2005-06-24 2006-12-28 Affymetrix, Inc. Analysis of methylation using nucleic acid arrays
ATE531820T1 (en) * 2005-09-14 2011-11-15 Human Genetic Signatures Pty HEALTH CONDITION TEST
WO2007057231A1 (en) 2005-11-17 2007-05-24 Epigenomics Ag Method for the determination of the dna methylation level of a cpg position in identical cells within a tissue sample
US7820385B2 (en) * 2006-03-22 2010-10-26 The United States Of America As Represented By The Department Of Health And Human Services, Centers For Disease Control And Prevention Method for retaining methylation pattern in globally amplified DNA
US7901882B2 (en) * 2006-03-31 2011-03-08 Affymetrix, Inc. Analysis of methylation using nucleic acid arrays
US8084734B2 (en) * 2006-05-26 2011-12-27 The George Washington University Laser desorption ionization and peptide sequencing on laser induced silicon microcolumn arrays
US20080050738A1 (en) * 2006-05-31 2008-02-28 Human Genetic Signatures Pty Ltd. Detection of target nucleic acid
WO2008096146A1 (en) 2007-02-07 2008-08-14 Solexa Limited Preparation of templates for methylation analysis
EP2126120A4 (en) * 2007-03-16 2011-03-30 Human Genetic Signatures Pty Assay for gene expression
SI3101141T1 (en) 2007-06-08 2020-03-31 Epigenomics Ag Method for methylation analysis
CN101918595A (en) * 2007-11-27 2010-12-15 人类遗传标记控股有限公司 Enzymes for amplification and copying bisulphite modified nucleic acids
WO2009079703A1 (en) * 2007-12-20 2009-07-02 Human Genetic Signatures Pty Ltd Elimination of contaminants associated with nucleic acid amplification
EP2340314B8 (en) 2008-10-22 2015-02-18 Illumina, Inc. Preservation of information related to genomic dna methylation
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US9490113B2 (en) * 2009-04-07 2016-11-08 The George Washington University Tailored nanopost arrays (NAPA) for laser desorption ionization in mass spectrometry
US9624530B2 (en) 2009-08-03 2017-04-18 Epigenomics Ag Methods for preservation of genomic DNA sequence complexity
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EP1090138A4 (en) * 1998-06-24 2003-01-02 Glaxo Group Ltd Nucleotide detection method
DE10010280B4 (en) * 2000-02-25 2006-08-10 Epigenomics Ag Method for the detection of cytosine methylation in DNA samples
DE10029915B4 (en) * 2000-06-19 2005-06-16 Epigenomics Ag Method for the detection of cytosine methylations

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