AU2001273840A1 - Detection of variations in the DNA methylation profile - Google Patents
Detection of variations in the DNA methylation profileInfo
- Publication number
- AU2001273840A1 AU2001273840A1 AU2001273840A AU7384001A AU2001273840A1 AU 2001273840 A1 AU2001273840 A1 AU 2001273840A1 AU 2001273840 A AU2001273840 A AU 2001273840A AU 7384001 A AU7384001 A AU 7384001A AU 2001273840 A1 AU2001273840 A1 AU 2001273840A1
- Authority
- AU
- Australia
- Prior art keywords
- variations
- detection
- dna methylation
- methylation profile
- profile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 230000007067 DNA methylation Effects 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10019058A DE10019058A1 (en) | 2000-04-06 | 2000-04-06 | Designing primers and probes for analyzing diseases associated with cytosine methylation state e.g. arthritis, cancer, aging, arteriosclerosis comprising fragments of chemically modified genes associated with cell cycle |
DE10019058 | 2000-04-06 | ||
PCT/DE2001/001486 WO2001077373A2 (en) | 2000-04-06 | 2001-04-06 | Detection of variations in the dna methylation profile |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001273840A1 true AU2001273840A1 (en) | 2001-10-23 |
Family
ID=7639087
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001273840A Abandoned AU2001273840A1 (en) | 2000-04-06 | 2001-04-06 | Detection of variations in the DNA methylation profile |
Country Status (5)
Country | Link |
---|---|
US (1) | US20070026393A1 (en) |
EP (1) | EP1278892A1 (en) |
AU (1) | AU2001273840A1 (en) |
DE (1) | DE10019058A1 (en) |
WO (1) | WO2001077373A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109852687A (en) * | 2019-03-26 | 2019-06-07 | 普文博泰生物科技(佛山)有限公司 | A kind of composite amplification primer sets, kit and method for genetic screening |
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EP1340818A1 (en) * | 2002-02-27 | 2003-09-03 | Epigenomics AG | Method and nucleic acids for the analysis of a colon cell proliferative disorder |
WO2004020662A2 (en) * | 2002-08-27 | 2004-03-11 | Epigenomics Ag | Method and nucleic acids for the analysis of breast cell proliferative disorders |
JP4781267B2 (en) * | 2003-08-14 | 2011-09-28 | ケース ウエスタン リザーブ ユニバーシティ | Method and composition for detecting colorectal cancer |
US8415100B2 (en) | 2003-08-14 | 2013-04-09 | Case Western Reserve University | Methods and compositions for detecting gastrointestinal and other cancers |
CA3050151C (en) * | 2003-11-26 | 2023-03-07 | Celera Corporation | Single nucleotide polymorphisms associated with cardiovascular disorders and statin response, methods of detection and uses thereof |
US7608458B2 (en) * | 2004-02-05 | 2009-10-27 | Medtronic, Inc. | Identifying patients at risk for life threatening arrhythmias |
WO2005118872A2 (en) | 2004-06-01 | 2005-12-15 | The Regents Of The University Of Michigan | Methods and kits for diagnosing or monitoring autoimmune and chronic inflammatory diseases |
US8027791B2 (en) * | 2004-06-23 | 2011-09-27 | Medtronic, Inc. | Self-improving classification system |
US20050287574A1 (en) * | 2004-06-23 | 2005-12-29 | Medtronic, Inc. | Genetic diagnostic method for SCD risk stratification |
US8335652B2 (en) * | 2004-06-23 | 2012-12-18 | Yougene Corp. | Self-improving identification method |
WO2006088978A1 (en) | 2005-02-16 | 2006-08-24 | Epigenomics, Inc. | Method for determining the methylation pattern of a polynucleic acid |
US7932027B2 (en) | 2005-02-16 | 2011-04-26 | Epigenomics Ag | Method for determining the methylation pattern of a polynucleic acid |
WO2006110585A2 (en) * | 2005-04-07 | 2006-10-19 | Novartis Vaccines And Diagnostics Inc. | Cancer-related genes (prlr) |
US7449297B2 (en) | 2005-04-14 | 2008-11-11 | Euclid Diagnostics Llc | Methods of copying the methylation pattern of DNA during isothermal amplification and microarrays |
JP5133238B2 (en) | 2005-04-15 | 2013-01-30 | エピゲノミックス アクチェンゲゼルシャフト | Method for providing a DNA fragment from a remote sample |
US7439024B2 (en) | 2005-06-01 | 2008-10-21 | The United States Of America As Represented By The Department Of Veterans Affairs | Methods and kits for diagnosing or monitoring autoimmune and chronic inflammatory diseases |
WO2007003397A2 (en) * | 2005-07-01 | 2007-01-11 | Epigenomics Ag | Method and nucleic acids for the improved treatment of cancers |
AU2006339538A1 (en) * | 2005-11-08 | 2007-09-13 | Euclid Diagnostics Llc | Materials and methods for assaying for methylation of CpG islands associated with genes in the evaluation of cancer |
CA2648385C (en) | 2006-04-04 | 2020-09-01 | Singulex, Inc. | Highly sensitive system and methods for analysis of troponin |
US7838250B1 (en) | 2006-04-04 | 2010-11-23 | Singulex, Inc. | Highly sensitive system and methods for analysis of troponin |
EP2229588A4 (en) * | 2007-11-14 | 2011-05-25 | Medtronic Inc | Diagnostic kits and methods for scd or sca therapy selection |
US20110143956A1 (en) * | 2007-11-14 | 2011-06-16 | Medtronic, Inc. | Diagnostic Kits and Methods for SCD or SCA Therapy Selection |
EP2297346B1 (en) | 2008-05-15 | 2015-04-15 | Ribomed Biotechnologies, Inc. | METHODS AND REAGENTS FOR DETECTING CpG METHYLATION WITH A METHYL CpG BINDING PROTEIN (MBP) |
CA2728171A1 (en) * | 2008-08-27 | 2010-03-04 | H. Lundbeck A/S | System and methods for measuring biomarker profiles |
US9115386B2 (en) | 2008-09-26 | 2015-08-25 | Children's Medical Center Corporation | Selective oxidation of 5-methylcytosine by TET-family proteins |
KR20120007002A (en) | 2009-03-15 | 2012-01-19 | 리보메드 바이오테크놀로지스, 인코퍼레이티드 | Abscription based molecular detection |
US8950910B2 (en) | 2009-03-26 | 2015-02-10 | Cree, Inc. | Lighting device and method of cooling lighting device |
EP2430184A2 (en) * | 2009-05-12 | 2012-03-21 | Medtronic, Inc. | Sca risk stratification by predicting patient response to anti-arrhythmics |
WO2010144358A1 (en) | 2009-06-08 | 2010-12-16 | Singulex, Inc. | Highly sensitive biomarker panels |
EP2308998A1 (en) * | 2009-09-18 | 2011-04-13 | Universitätsklinikum Jena Körperschaft des öffentlichen Rechts und Teilkörperschaft der Friedrich-Schiller-Universität Jena | Method for early diagnosis of carcinomas of the anogenital tract |
ES2715226T3 (en) * | 2010-09-13 | 2019-06-03 | Clinical Genomics Pty Ltd | Epigenetic markers of colorectal cancers and diagnostic methods that use them |
US9797016B2 (en) | 2010-10-19 | 2017-10-24 | Oslo Universitetssykehus Hf | Methods and biomarkers for detection of bladder cancer |
JP6003033B2 (en) * | 2010-11-11 | 2016-10-05 | ソニー株式会社 | Nucleic acid detection method, sample optical observation method, and phosphor |
US20140323321A1 (en) * | 2010-12-13 | 2014-10-30 | The Johns Hopkins University | Detection of head and neck cancer using hypermethylated gene detection |
RU2475740C1 (en) * | 2011-09-26 | 2013-02-20 | Федеральное государственное бюджетное учреждение "Ивановский научно-исследовательский институт материнства и детства имени В.Н. Городкова" Министерства здравоохранения и социального развития Российской Федерации | Method of detecting hereditary predisposition to fast growth of uterine myoma |
GB201207788D0 (en) * | 2012-05-03 | 2012-06-13 | Univ Newcastle | Methods relating to identification of susceptibility to liver injury |
ES2669214T3 (en) | 2011-12-13 | 2018-05-24 | Oslo Universitetssykehus Hf | Procedures and kits for the detection of methylation status |
EP3351644B1 (en) | 2012-11-30 | 2020-01-29 | Cambridge Epigenetix Limited | Oxidising agent for modified nucleotides |
WO2015017575A2 (en) * | 2013-08-01 | 2015-02-05 | Dignify Therapeutics, Inc. | Compositions and methods for inducing urinary voiding and defecation |
CN104195229A (en) * | 2014-07-24 | 2014-12-10 | 益善生物技术股份有限公司 | Epidermal growth factor receptor inhibitor drug curative effect related gene expression detection liquid chip kit |
US11459573B2 (en) | 2015-09-30 | 2022-10-04 | Trustees Of Boston University | Deadman and passcode microbial kill switches |
EP3481953A4 (en) * | 2016-07-06 | 2020-04-15 | Youhealth Biotech, Limited | Liver cancer methylation markers and uses thereof |
RU2630669C1 (en) * | 2016-07-21 | 2017-09-11 | Федеральное бюджетное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" (ФБУН ГНЦ ВБ "Вектор") | Method for determination of methylation of colorectal cancer tumor marker genes regulatory regions pucgpy sites by glad-pcr analysis, and set of oligonucleotide primers and fluorescence-labelled probes for implementation of this method |
US20220049305A1 (en) * | 2018-09-14 | 2022-02-17 | Gen Shinozaki | Systems and methods for detection of delirium risk using epigenetic markers |
KR102281657B1 (en) * | 2019-12-23 | 2021-07-26 | 한림대학교 산학협력단 | CDHR5 Gene hypermethylation marker for diagnosis of delayed cerebral ischemia |
KR102281644B1 (en) * | 2019-12-23 | 2021-07-23 | 한림대학교 산학협력단 | INSR Gene hypermethylation marker for diagnosis of delayed cerebral ischemia |
EP4083231A1 (en) | 2020-07-30 | 2022-11-02 | Cambridge Epigenetix Limited | Compositions and methods for nucleic acid analysis |
CN111972399B (en) * | 2020-08-06 | 2021-11-30 | 温州医科大学 | Preservation solution for maintaining activity of liver cells |
EP4196611A1 (en) | 2020-08-15 | 2023-06-21 | Regeneron Pharmaceuticals, Inc. | Treatment of obesity in subjects having variant nucleic acid molecules encoding calcitonin receptor (calcr) |
CN115521956B (en) * | 2022-10-21 | 2024-04-19 | 江苏诚信药业有限公司 | Method for synthesizing L-carnosine by biological enzyme catalysis |
CN115487301B (en) * | 2022-11-08 | 2023-07-07 | 四川大学华西医院 | Use of IL-13 inhibitors for the preparation of a medicament for the delay or treatment of retinitis pigmentosa |
CN116790761B (en) * | 2023-08-22 | 2023-11-17 | 湖南宏雅基因技术有限公司 | Biomarker for benign and malignant lesions of endometrium and application of biomarker |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2672618B1 (en) * | 1991-02-13 | 1994-12-02 | Centre Nat Rech Scient | NUCLEIC ACID FRAGMENT OF THE X CHROMOSOME REGION INVOLVED IN FRAGILE X SYNDROME, NUCLEOTIDE PROBE AND METHOD FOR DIAGNOSING MENTAL DELAY WITH X FRAGILE. |
GB9311113D0 (en) * | 1993-05-28 | 1993-07-14 | Medical Res Council | Probes |
US5912147A (en) * | 1996-10-22 | 1999-06-15 | Health Research, Inc. | Rapid means of quantitating genomic instability |
US6251594B1 (en) * | 1997-06-09 | 2001-06-26 | Usc/Norris Comprehensive Cancer Ctr. | Cancer diagnostic method based upon DNA methylation differences |
DE19754482A1 (en) * | 1997-11-27 | 1999-07-01 | Epigenomics Gmbh | Process for making complex DNA methylation fingerprints |
US6692909B1 (en) * | 1998-04-01 | 2004-02-17 | Whitehead Institute For Biomedical Research | Coding sequence polymorphisms in vascular pathology genes |
WO1999055915A2 (en) * | 1998-04-29 | 1999-11-04 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | IDENTIFICATION OF POLYMORPHISMS IN THE PCTG4 REGION OF Xq13 |
US6525185B1 (en) * | 1998-05-07 | 2003-02-25 | Affymetrix, Inc. | Polymorphisms associated with hypertension |
EP1112381A1 (en) * | 1998-09-19 | 2001-07-04 | AstraZeneca AB | Polymorphisms in the human alpha4 integrin subunit gene, suitable for diagnosis and treatment of integrin ligand mediated diseases |
US7700324B1 (en) * | 1998-11-03 | 2010-04-20 | The Johns Hopkins University School Of Medicine | Methylated CpG island amplification (MCA) |
WO2000029622A2 (en) * | 1998-11-17 | 2000-05-25 | Curagen Corporation | Nucleic acids containing single nucleotide polymorphisms and methods of use thereof |
US6670464B1 (en) * | 1998-11-17 | 2003-12-30 | Curagen Corporation | Nucleic acids containing single nucleotide polymorphisms and methods of use thereof |
DE19853398C1 (en) * | 1998-11-19 | 2000-03-16 | Epigenomics Gmbh | Identification of 5-methylcytosine positions in genomic DNA by chemical modification, amplification and heteroduplex formation |
-
2000
- 2000-04-06 DE DE10019058A patent/DE10019058A1/en not_active Ceased
-
2001
- 2001-04-06 EP EP01940158A patent/EP1278892A1/en not_active Ceased
- 2001-04-06 WO PCT/DE2001/001486 patent/WO2001077373A2/en active Application Filing
- 2001-04-06 AU AU2001273840A patent/AU2001273840A1/en not_active Abandoned
- 2001-04-06 US US10/240,970 patent/US20070026393A1/en not_active Abandoned
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109852687A (en) * | 2019-03-26 | 2019-06-07 | 普文博泰生物科技(佛山)有限公司 | A kind of composite amplification primer sets, kit and method for genetic screening |
Also Published As
Publication number | Publication date |
---|---|
DE10019058A1 (en) | 2001-12-20 |
EP1278892A1 (en) | 2003-01-29 |
WO2001077373A2 (en) | 2001-10-18 |
US20070026393A1 (en) | 2007-02-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase | ||
TH | Corrigenda |
Free format text: IN VOL 16, NO 10, PAGE(S) 2150-2167 UNDER THE HEADING APPLICATIONS LAPSED, REFUSED OR WITHDRAWN PLEASE DELETE ALL REFERENCE TO APPLICATION NO. 37189/01, 39165/01, 42263/01, 44489/01, 48491/01, 48494/01, 50604/01, 50624/01, 50628/01, 58215/01, 60018/01, 60051/01, 63811/01, 73840/01 AND 87748/01 |
|
MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |