IL143150A0 - A process for the preparation of n,n'-bis[2,3-dihydroxypropyl]-5[hydroxyacetyl) methylamino]-2,4,5-triiodo-1,3-benzenedicarboxamide - Google Patents

A process for the preparation of n,n'-bis[2,3-dihydroxypropyl]-5[hydroxyacetyl) methylamino]-2,4,5-triiodo-1,3-benzenedicarboxamide

Info

Publication number
IL143150A0
IL143150A0 IL14315099A IL14315099A IL143150A0 IL 143150 A0 IL143150 A0 IL 143150A0 IL 14315099 A IL14315099 A IL 14315099A IL 14315099 A IL14315099 A IL 14315099A IL 143150 A0 IL143150 A0 IL 143150A0
Authority
IL
Israel
Prior art keywords
triiodo
hydroxyacetyl
dihydroxypropyl
methylamino
bis
Prior art date
Application number
IL14315099A
Other languages
English (en)
Original Assignee
Bracco Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Int Bv filed Critical Bracco Int Bv
Publication of IL143150A0 publication Critical patent/IL143150A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Polyamides (AREA)
IL14315099A 1998-11-27 1999-11-25 A process for the preparation of n,n'-bis[2,3-dihydroxypropyl]-5[hydroxyacetyl) methylamino]-2,4,5-triiodo-1,3-benzenedicarboxamide IL143150A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998MI002574A IT1303797B1 (it) 1998-11-27 1998-11-27 Processo per la preparazione di n,n'-bis(2,3-diidrossipropil)-5-((idrossiacetil)metilammino)-2,4,6-triiodo-1,3-benzendicarbossammide.
PCT/EP1999/009118 WO2000032561A1 (en) 1998-11-27 1999-11-25 A process for the preparation of n,n'-bis[2, 3-dihydroxypropyl] -5-[ (hydroxyacetyl) methylamino]-2, 4,6-triiodo-1, 3-benzenedi carboxamide

Publications (1)

Publication Number Publication Date
IL143150A0 true IL143150A0 (en) 2002-04-21

Family

ID=11381150

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14315099A IL143150A0 (en) 1998-11-27 1999-11-25 A process for the preparation of n,n'-bis[2,3-dihydroxypropyl]-5[hydroxyacetyl) methylamino]-2,4,5-triiodo-1,3-benzenedicarboxamide

Country Status (24)

Country Link
US (1) US6420603B1 (xx)
EP (1) EP1133466B1 (xx)
JP (1) JP4439123B2 (xx)
KR (1) KR100630400B1 (xx)
CN (1) CN1163474C (xx)
AT (1) ATE247630T1 (xx)
AU (1) AU753601B2 (xx)
BR (1) BR9915608B1 (xx)
CA (1) CA2351717C (xx)
CZ (1) CZ296096B6 (xx)
DE (1) DE69910609T2 (xx)
EA (1) EA003253B1 (xx)
ES (1) ES2205949T3 (xx)
HK (1) HK1040988B (xx)
HR (1) HRP20010393B1 (xx)
HU (1) HU229092B1 (xx)
IL (1) IL143150A0 (xx)
IT (1) IT1303797B1 (xx)
ME (2) ME00606B (xx)
NO (1) NO327037B1 (xx)
RS (1) RS50038B (xx)
SK (1) SK285050B6 (xx)
TR (1) TR200101439T2 (xx)
WO (1) WO2000032561A1 (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2093206A1 (en) * 2008-02-20 2009-08-26 BRACCO IMAGING S.p.A. Process for the iodination of aromatic compounds
EP2243767A1 (en) 2009-04-21 2010-10-27 Bracco Imaging S.p.A Process for the iodination of aromatic compounds
DK2451994T3 (da) * 2009-07-07 2014-01-20 Bracco Imaging Spa Fremgangsmåde til fremstilling af et ioderende middel
EP2277846A1 (en) * 2009-07-21 2011-01-26 GE Healthcare AS Obtaining free iodine in preparation of aqueous iodine chloride by adding potassium iodide
EP2394984A1 (en) * 2010-06-10 2011-12-14 Bracco Imaging S.p.A Process for the iodination of phenolic derivatives
IT1403988B1 (it) * 2010-07-15 2013-11-08 Bracco Imaging Spa Processo per la preparazione di agenti di contrasto.
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
KR101833334B1 (ko) * 2016-04-29 2018-02-28 (주)유케이케미팜 신규 중간체 화합물 및 이를 이용한 이오메프롤의 제조방법
KR102128423B1 (ko) 2018-09-17 2020-07-01 (주)유케이케미팜 조영제 이오메프롤의 제조방법
JP2024536065A (ja) 2021-09-24 2024-10-04 ブラッコ・イメージング・ソシエタ・ペル・アチオニ Ｎ，ｎ’－（２，３－ジヒドロキシプロピル）－５－ヒドロキシ－１，３－ベンゼンジカルボキサミドの電気化学的ヨウ素化
WO2023209165A1 (en) 2022-04-29 2023-11-02 Bracco Imaging Spa Process for the preparation of 2,4,6-triiodophenol derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196363B (it) * 1984-12-10 1988-11-16 Bracco Ind Chimica Spa Derivati dell'acido 5-alcossi-2,4,6-triiodo- o -tribromo-isoftalico,metodo per la loro preparazione e relativi mezzi di contrasto radiologici
KR960016747B1 (ko) 1987-05-22 1996-12-20 브라코 인터내셔날 비. 브이 5-아실아미노-2,4,6-트리요오도-또는 트리브로모-벤조산 유도체의 제조 방법

Also Published As

Publication number Publication date
ITMI982574A1 (it) 2000-05-27
SK7052001A3 (en) 2001-12-03
CN1328539A (zh) 2001-12-26
NO20012547L (no) 2001-07-25
HK1040988B (zh) 2005-04-29
HK1040988A1 (en) 2002-06-28
IT1303797B1 (it) 2001-02-23
CZ296096B6 (cs) 2006-01-11
HUP0104507A3 (en) 2004-07-28
TR200101439T2 (tr) 2001-10-22
HRP20010393B1 (en) 2004-04-30
KR20010101053A (ko) 2001-11-14
ME00606B (me) 2011-12-20
DE69910609T2 (de) 2004-03-18
JP4439123B2 (ja) 2010-03-24
ATE247630T1 (de) 2003-09-15
CN1163474C (zh) 2004-08-25
AU1386200A (en) 2000-06-19
AU753601B2 (en) 2002-10-24
JP2002531432A (ja) 2002-09-24
BR9915608B1 (pt) 2010-11-16
CA2351717C (en) 2010-10-05
HUP0104507A2 (hu) 2002-04-29
SK285050B6 (sk) 2006-05-04
US6420603B1 (en) 2002-07-16
HU229092B1 (en) 2013-07-29
HRP20010393A2 (en) 2002-06-30
NO20012547D0 (no) 2001-05-23
EP1133466A1 (en) 2001-09-19
MEP8809A (en) 2011-12-20
CA2351717A1 (en) 2000-06-08
KR100630400B1 (ko) 2006-10-02
EA003253B1 (ru) 2003-02-27
ES2205949T3 (es) 2004-05-01
DE69910609D1 (de) 2003-09-25
BR9915608A (pt) 2001-08-14
WO2000032561A1 (en) 2000-06-08
EA200100462A1 (ru) 2001-12-24
YU37101A (sh) 2003-04-30
NO327037B1 (no) 2009-04-06
RS50038B (sr) 2008-11-28
CZ20011833A3 (cs) 2001-10-17
EP1133466B1 (en) 2003-08-20

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