IL142516A0 - Specific genetic modification of the activity of trehalose-6-phosphate synthase and expression in a homologous or heterologous environment - Google Patents

Specific genetic modification of the activity of trehalose-6-phosphate synthase and expression in a homologous or heterologous environment

Info

Publication number
IL142516A0
IL142516A0 IL14251699A IL14251699A IL142516A0 IL 142516 A0 IL142516 A0 IL 142516A0 IL 14251699 A IL14251699 A IL 14251699A IL 14251699 A IL14251699 A IL 14251699A IL 142516 A0 IL142516 A0 IL 142516A0
Authority
IL
Israel
Prior art keywords
gene
plant
expression
tps
yeast
Prior art date
Application number
IL14251699A
Other languages
English (en)
Original Assignee
Inst De Biotechnologia Unam
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst De Biotechnologia Unam filed Critical Inst De Biotechnologia Unam
Publication of IL142516A0 publication Critical patent/IL142516A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8245—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified carbohydrate or sugar alcohol metabolism, e.g. starch biosynthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL14251699A 1998-10-15 1999-10-15 Specific genetic modification of the activity of trehalose-6-phosphate synthase and expression in a homologous or heterologous environment IL142516A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98203469A EP1002867A1 (de) 1998-10-15 1998-10-15 Spezifische genetische Veränderung der Aktivität von Trehalose-6-phosphatsynthase und Expression in einer homologen und heterologen Umgebung
PCT/EP1999/007913 WO2000022141A2 (en) 1998-10-15 1999-10-15 Specific genetic modification of the activity of trehalose-6-phosphate synthase and expression in a homologous or heterologous environment

Publications (1)

Publication Number Publication Date
IL142516A0 true IL142516A0 (en) 2002-03-10

Family

ID=8234221

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14251699A IL142516A0 (en) 1998-10-15 1999-10-15 Specific genetic modification of the activity of trehalose-6-phosphate synthase and expression in a homologous or heterologous environment
IL142516A IL142516A (en) 1998-10-15 2001-04-10 Specific genetic modifications of trehalose-6-phosphate synthase for increased activity in eucariotic organisms

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL142516A IL142516A (en) 1998-10-15 2001-04-10 Specific genetic modifications of trehalose-6-phosphate synthase for increased activity in eucariotic organisms

Country Status (11)

Country Link
US (4) US6872870B1 (de)
EP (2) EP1002867A1 (de)
JP (1) JP4948704B2 (de)
AT (1) ATE332975T1 (de)
AU (1) AU780477B2 (de)
BR (1) BR9915757A (de)
CA (1) CA2346877A1 (de)
DE (1) DE69932343T2 (de)
ES (1) ES2268902T3 (de)
IL (2) IL142516A0 (de)
WO (1) WO2000022141A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7214858B2 (en) 1999-03-31 2007-05-08 E. I. Du Pont De Nemours And Company Plant genes encoding trehalose metabolism enzymes
KR100440725B1 (ko) 2002-06-20 2004-07-15 주식회사 그린진 바이오텍 비생물성 스트레스에 대한 단자엽 식물의 내성을증가시키는 방법
WO2004044143A2 (en) * 2002-11-06 2004-05-27 Cornell Research Foundation, Inc. Tps plant gene constructs and transformants
AU2003290635A1 (en) * 2002-11-08 2004-06-03 Paradigm Genetics, Inc. Methods for the identification of trehalose-6-phosphate synthase as antibiotics
EP1989312B1 (de) 2006-01-27 2011-10-19 VIB, vzw Verwendung von trehalose-6-phosphat-synthase zur modulation von pflanzenwachstum
CN101374952B (zh) * 2006-01-27 2011-07-06 福拉姆斯大学生物技术研究所 海藻糖-6-磷酸合酶调节植物生长的用途
JP4305547B2 (ja) * 2006-10-27 2009-07-29 エプソンイメージングデバイス株式会社 実装構造体、電気光学装置、電子機器及び実装構造体の製造方法
EP3659414A1 (de) 2013-09-04 2020-06-03 Indigo Ag, Inc. Landwirtschaftliche endophytenpflanzenzusammensetzungen und verfahren zur verwendung
CA2957920A1 (en) 2014-08-11 2016-02-18 Butamax Advanced Biofuels Llc Yeast preparations and methods of making the same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69116413T2 (de) 1990-03-28 1996-05-30 Gist Brocades Nv Neue Hefestämme mit erhöhtem Trehalosegehalt, Verfahren zur Gewinnung solcher Hefen und Verwendung dieser Hefen
US6130368A (en) * 1992-02-14 2000-10-10 Btg International Ltd Transgenic plants producing trehalose
US5792921A (en) * 1992-02-14 1998-08-11 Londesborough; John Increasing the trehalose content of organisms by transforming them with combinations of the structural genes for trehalose synthase
US5422254A (en) * 1992-02-14 1995-06-06 Oy Alko Ab Method to increase the trehalose content of organisms by transforming them with the structural genes for the short and long chains of yeast trehalose synthase
FI943133A0 (fi) * 1994-06-29 1994-06-29 Alko Ab Oy Transgena vaexter
RO115650B1 (ro) * 1993-06-30 2000-04-28 Mogen Int Acid nucleic, secventa de acid nucleic si vector care determina producerea de trehaloza si procedeu de producere a plantelor cu un continut crescut de trehaloza
IL116564A0 (en) * 1995-01-04 1996-03-31 Mogen Int Process for producing trehalose in plants
IN1997CH00924A (en) * 1996-05-03 2005-03-04 Syngenta Mogen Bv Regulating metabolism by modifying the level of trehalose-6-phosphate
MX205414B (es) * 1996-05-08 2001-12-07 Univ Mexico Nacional Autonoma Metodo para incrementar de trehalosa de los organismos por medio de su transformacion con el adnc de la trehalosa-6-fosfato sintasa/fosfatasa de selaginella lepidophylla.

Also Published As

Publication number Publication date
US7781646B2 (en) 2010-08-24
DE69932343T2 (de) 2006-12-28
ES2268902T3 (es) 2007-03-16
BR9915757A (pt) 2003-01-07
US20110296554A1 (en) 2011-12-01
JP2002537759A (ja) 2002-11-12
WO2000022141A3 (en) 2000-07-27
CA2346877A1 (en) 2000-04-20
EP1002867A1 (de) 2000-05-24
US20050283852A1 (en) 2005-12-22
AU1152700A (en) 2000-05-01
US20140317785A1 (en) 2014-10-23
EP1121445B1 (de) 2006-07-12
JP4948704B2 (ja) 2012-06-06
DE69932343D1 (de) 2006-08-24
IL142516A (en) 2010-05-31
US6872870B1 (en) 2005-03-29
AU780477B2 (en) 2005-03-24
US8796505B2 (en) 2014-08-05
EP1121445A2 (de) 2001-08-08
WO2000022141A2 (en) 2000-04-20
ATE332975T1 (de) 2006-08-15

Similar Documents

Publication Publication Date Title
US8058053B2 (en) Modification of protein glycosylation in methylotrophic yeast
Decker et al. The moss bioreactor
CA2549932C (en) Production of heterologous glycosylated proteins in bryophyte cells
US7741539B2 (en) Transformed plant cell expressing five mammalian proteins involved in sialylation and a protein involved in galactosylation
CA2223881A1 (en) Isolated dna sequence capable of serving as regulatory element in a chimeric gene which can be used for the transformation of plants
JP6407872B2 (ja) 主に均一なグリカン構造を生成するためのピキア・パストリス（Ｐｉｃｈｉａｐａｓｔｏｒｉｓ）株
IL142516A0 (en) Specific genetic modification of the activity of trehalose-6-phosphate synthase and expression in a homologous or heterologous environment
MX2012004994A (es) Metodo para producir proteinas terapeuticas en pichia pastoris que carecen de actividad de dipeptidil aminopeptidasa.
JP5662363B2 (ja) 難発現性タンパク質の分泌のためのタンパク質融合因子（ｔｆｐ）を明らかにする方法、タンパク質融合因子（ｔｆｐ）ライブラリーを製造する方法、及び難発現性タンパク質の組み換え的生産方法
US20240209328A1 (en) Protein compositions and methods of production
JP5568702B2 (ja) 組換えポリペプチドの発現および翻訳後修飾の制御を標的化するための配列を有するポリペプチド
JPH08336387A (ja) ピキア属酵母由来の糖鎖伸長タンパク及びそのｄｎａ
Maleki et al. High expression of methylotrophic yeast-derived recombinant human erythropoietin in a pH-controlled batch system
US8003349B2 (en) YLMPO1 gene derived from yarrowia lipolytica and a process for preparing a glycoprotein not being mannosylphosphorylated by using a mutated yarrowia lipolytica in which YLMPO1 gene is disrupted
EP2789686A1 (de) Expression von phosphorylierten Glycoproteinen in Pflanzen
KR100798894B1 (ko) 재조합단백질 생산용 단백질융합인자
WO2012060389A1 (ja) シゾサッカロミセス属酵母の形質転換体およびその製造方法
CN117343950B (zh) 一种提高里氏木霉表达外源蛋白表达水平的方法
Terekhov et al. Expression of DNA-encoded antidote to organophosphorus toxins in the methylotrophic yeast Pichia pastoris
Nicolau Sanus Production of recombinant proteins with pharmaceutical and industrial applications in plants using a tobacco mosaic virus-derived vector
US20140137289A1 (en) Method For Accumulating A Protein In Plant Cell
JP2023158948A (ja) ｐｐＧｐｐ富化生物の製造方法及び生物
EP1904636B1 (de) Verbesserungen der proteinproduktion oder in zusammenhang damit
JPH04287683A (ja) 酵母変異株およびそれを利用するペプチドまたは蛋白質　　　　　　　　　　　等の製造方法