IL140884A0 - Novel dna cleaving antitumor agents - Google Patents
Novel dna cleaving antitumor agentsInfo
- Publication number
- IL140884A0 IL140884A0 IL14088499A IL14088499A IL140884A0 IL 140884 A0 IL140884 A0 IL 140884A0 IL 14088499 A IL14088499 A IL 14088499A IL 14088499 A IL14088499 A IL 14088499A IL 140884 A0 IL140884 A0 IL 140884A0
- Authority
- IL
- Israel
- Prior art keywords
- antitumor agents
- novel dna
- dna cleaving
- cleaving
- novel
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9311298P | 1998-07-16 | 1998-07-16 | |
| PCT/US1999/016171 WO2000003709A1 (en) | 1998-07-16 | 1999-07-16 | Novel dna-cleaving antitumor agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL140884A0 true IL140884A0 (en) | 2002-02-10 |
Family
ID=22237206
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14088499A IL140884A0 (en) | 1998-07-16 | 1999-07-16 | Novel dna cleaving antitumor agents |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6908948B1 (de) |
| EP (1) | EP1109552A4 (de) |
| JP (1) | JP2002539071A (de) |
| KR (1) | KR100763211B1 (de) |
| CN (1) | CN1243545C (de) |
| AU (1) | AU762972B2 (de) |
| CA (1) | CA2337517A1 (de) |
| IL (1) | IL140884A0 (de) |
| NZ (1) | NZ509273A (de) |
| RU (1) | RU2227029C2 (de) |
| WO (1) | WO2000003709A1 (de) |
| ZA (1) | ZA200100353B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8710012B2 (en) | 2003-07-14 | 2014-04-29 | Cls Therapeutics Limited | Method for treating oncological diseases |
| RU2269356C2 (ru) * | 2003-07-14 | 2006-02-10 | Дмитрий Дмитриевич Генкин | Способ лечения онкологических заболеваний |
| US8388951B2 (en) | 2003-07-14 | 2013-03-05 | Cls Therapeutics Limited | Method for treating systemic DNA mutation disease |
| US8431123B2 (en) | 2003-07-14 | 2013-04-30 | Cls Therapeutics Limited | Method for treating systemic bacterial, fungal and protozoan infection |
| EP1711455A4 (de) * | 2004-01-23 | 2007-11-07 | Univ Pennsylvania | Fazial amphiphile polyaryl- und polyarylalkinylpolymere und -oligomere und deren anwendungen |
| US8916151B2 (en) | 2005-04-25 | 2014-12-23 | Cls Therapeutics Limited | Method for treating a reduction of fertility |
| WO2008066403A1 (en) | 2006-11-28 | 2008-06-05 | Dmitry Dmitrievich Genkin | Method for treating human diseases associated with an increased deoxyribonucleic acid content in extracellular spaces of tissues and a medicinal preparation for carrying out said method |
| FR2914855A1 (fr) * | 2007-04-13 | 2008-10-17 | Oreal | Composition comprenant au moins un derive substitue de carbocyanine acetylenique, procede de traitement des fibres keratiniques la mettant en oeuvre et dispositif |
| US10617743B2 (en) | 2014-06-19 | 2020-04-14 | Cls Therapeutics Limited | Method to improve safety and efficacy of anti-cancer therapy |
| CN104513250B (zh) * | 2014-12-23 | 2016-11-23 | 南开大学 | 一种水溶性卟啉的合成方法及其光催化应用 |
| RU2726131C2 (ru) | 2015-05-22 | 2020-07-09 | Дмитрий Дмитриевич Генкин | Внеклеточная днк в качестве терапевтической мишени при нейродегенерации |
| CN107095876B (zh) * | 2017-05-24 | 2019-12-03 | 上海交通大学医学院 | 二苯基联烯基氧膦化合物在制备治疗肺癌药物中的应用 |
| WO2019143272A1 (en) | 2018-01-16 | 2019-07-25 | Cls Therapeutics Limited | Treatment of diseases by liver expression of an enzyme which has a deoxyribonuclease (dnase) activity |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5098920A (en) * | 1990-05-04 | 1992-03-24 | G. D. Searle & Co. | 1h-substituted-1,2,4-triazole compounds and methods of use thereof for treatment of cardiovascular disorders |
| US5767142A (en) | 1996-03-20 | 1998-06-16 | Rutgers, The State University Of New Jersey | Trisbenzimidazoles useful as topoisomerase I inhibitors |
| US6297284B1 (en) * | 1998-07-16 | 2001-10-02 | Research Development Foundation | DNA-cleaving antitumor agents |
-
1999
- 1999-07-16 KR KR1020017000657A patent/KR100763211B1/ko not_active IP Right Cessation
- 1999-07-16 CA CA002337517A patent/CA2337517A1/en not_active Abandoned
- 1999-07-16 IL IL14088499A patent/IL140884A0/xx not_active IP Right Cessation
- 1999-07-16 NZ NZ509273A patent/NZ509273A/en unknown
- 1999-07-16 AU AU51082/99A patent/AU762972B2/en not_active Ceased
- 1999-07-16 EP EP99935648A patent/EP1109552A4/de not_active Withdrawn
- 1999-07-16 RU RU2001104426/15A patent/RU2227029C2/ru not_active IP Right Cessation
- 1999-07-16 WO PCT/US1999/016171 patent/WO2000003709A1/en not_active Application Discontinuation
- 1999-07-16 JP JP2000559844A patent/JP2002539071A/ja not_active Withdrawn
- 1999-07-16 US US09/356,303 patent/US6908948B1/en not_active Expired - Fee Related
- 1999-07-16 CN CNB998098485A patent/CN1243545C/zh not_active Expired - Fee Related
-
2001
- 2001-01-11 ZA ZA200100353A patent/ZA200100353B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1313766A (zh) | 2001-09-19 |
| AU762972B2 (en) | 2003-07-10 |
| WO2000003709A1 (en) | 2000-01-27 |
| JP2002539071A (ja) | 2002-11-19 |
| AU5108299A (en) | 2000-02-07 |
| KR20010083116A (ko) | 2001-08-31 |
| KR100763211B1 (ko) | 2007-10-08 |
| CA2337517A1 (en) | 2000-01-27 |
| EP1109552A4 (de) | 2007-11-07 |
| ZA200100353B (en) | 2002-01-10 |
| EP1109552A1 (de) | 2001-06-27 |
| NZ509273A (en) | 2003-05-30 |
| RU2227029C2 (ru) | 2004-04-20 |
| CN1243545C (zh) | 2006-03-01 |
| US6908948B1 (en) | 2005-06-21 |
| WO2000003709A9 (en) | 2000-07-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB2338672B (en) | Toolholder | |
| GB9808145D0 (en) | Assay | |
| IL140884A0 (en) | Novel dna cleaving antitumor agents | |
| HK1049682B (zh) | 內切-β-N-乙酰葡糖胺糖苷酶基因 | |
| DE69833112D1 (en) | Rna polymerase | |
| GB9817704D0 (en) | Gene switch | |
| GB9817909D0 (en) | DNA constructs | |
| GB9818931D0 (en) | Photobioreactor | |
| GB9809160D0 (en) | Assay | |
| EP1038957A4 (de) | Gen tsa305 | |
| EP0998924A4 (de) | Antitumor-wirkstoffe | |
| AU4513599A (en) | Nucleotide sequence | |
| IL140295A0 (en) | Novel biocontrol agents | |
| GB9724828D0 (en) | Gene | |
| GB9827585D0 (en) | Assay method | |
| GB2335889B (en) | Car | |
| GB9828848D0 (en) | Dna | |
| GB9806702D0 (en) | Dna | |
| GB9812822D0 (en) | Dna | |
| GB9818734D0 (en) | Gene | |
| GB9809753D0 (en) | Gene | |
| GB9817566D0 (en) | Gene | |
| CA83807S (en) | Chisel | |
| GB9717913D0 (en) | Dna | |
| GB9704070D0 (en) | Dna |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |