IL140884A0 - Novel dna cleaving antitumor agents - Google Patents
Novel dna cleaving antitumor agentsInfo
- Publication number
- IL140884A0 IL140884A0 IL14088499A IL14088499A IL140884A0 IL 140884 A0 IL140884 A0 IL 140884A0 IL 14088499 A IL14088499 A IL 14088499A IL 14088499 A IL14088499 A IL 14088499A IL 140884 A0 IL140884 A0 IL 140884A0
- Authority
- IL
- Israel
- Prior art keywords
- antitumor agents
- novel dna
- dna cleaving
- cleaving
- novel
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9311298P | 1998-07-16 | 1998-07-16 | |
PCT/US1999/016171 WO2000003709A1 (en) | 1998-07-16 | 1999-07-16 | Novel dna-cleaving antitumor agents |
Publications (1)
Publication Number | Publication Date |
---|---|
IL140884A0 true IL140884A0 (en) | 2002-02-10 |
Family
ID=22237206
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14088499A IL140884A0 (en) | 1998-07-16 | 1999-07-16 | Novel dna cleaving antitumor agents |
Country Status (12)
Country | Link |
---|---|
US (1) | US6908948B1 (xx) |
EP (1) | EP1109552A4 (xx) |
JP (1) | JP2002539071A (xx) |
KR (1) | KR100763211B1 (xx) |
CN (1) | CN1243545C (xx) |
AU (1) | AU762972B2 (xx) |
CA (1) | CA2337517A1 (xx) |
IL (1) | IL140884A0 (xx) |
NZ (1) | NZ509273A (xx) |
RU (1) | RU2227029C2 (xx) |
WO (1) | WO2000003709A1 (xx) |
ZA (1) | ZA200100353B (xx) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8431123B2 (en) | 2003-07-14 | 2013-04-30 | Cls Therapeutics Limited | Method for treating systemic bacterial, fungal and protozoan infection |
US8710012B2 (en) | 2003-07-14 | 2014-04-29 | Cls Therapeutics Limited | Method for treating oncological diseases |
RU2269356C2 (ru) * | 2003-07-14 | 2006-02-10 | Дмитрий Дмитриевич Генкин | Способ лечения онкологических заболеваний |
US8388951B2 (en) | 2003-07-14 | 2013-03-05 | Cls Therapeutics Limited | Method for treating systemic DNA mutation disease |
AU2005208771B2 (en) * | 2004-01-23 | 2011-11-24 | The Trustees Of The University Of Pennsylvania | Facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers and uses thereof |
US8916151B2 (en) | 2005-04-25 | 2014-12-23 | Cls Therapeutics Limited | Method for treating a reduction of fertility |
PL2095825T3 (pl) | 2006-11-28 | 2011-12-30 | Cls Therapeutics Ltd | Sposób leczenia ludzkich chorób związanych ze zwiększoną zawartością kwasu deoksyrybonukleinowego w przestrzeniach pozakomórkowych i tkankach i preparat leczniczy do przeprowadzenia tego sposobu |
FR2914855A1 (fr) | 2007-04-13 | 2008-10-17 | Oreal | Composition comprenant au moins un derive substitue de carbocyanine acetylenique, procede de traitement des fibres keratiniques la mettant en oeuvre et dispositif |
US10617743B2 (en) | 2014-06-19 | 2020-04-14 | Cls Therapeutics Limited | Method to improve safety and efficacy of anti-cancer therapy |
CN104513250B (zh) * | 2014-12-23 | 2016-11-23 | 南开大学 | 一种水溶性卟啉的合成方法及其光催化应用 |
RU2726131C2 (ru) | 2015-05-22 | 2020-07-09 | Дмитрий Дмитриевич Генкин | Внеклеточная днк в качестве терапевтической мишени при нейродегенерации |
CN107095876B (zh) * | 2017-05-24 | 2019-12-03 | 上海交通大学医学院 | 二苯基联烯基氧膦化合物在制备治疗肺癌药物中的应用 |
KR20200122320A (ko) | 2018-01-16 | 2020-10-27 | 씨엘에스 테라퓨틱스 리미티드 | 데옥시리보뉴클레아제 (dnase) 활성을 갖는 효소의 간 발현에 의한 질환의 치료 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5098920A (en) * | 1990-05-04 | 1992-03-24 | G. D. Searle & Co. | 1h-substituted-1,2,4-triazole compounds and methods of use thereof for treatment of cardiovascular disorders |
US5767142A (en) * | 1996-03-20 | 1998-06-16 | Rutgers, The State University Of New Jersey | Trisbenzimidazoles useful as topoisomerase I inhibitors |
US6297284B1 (en) * | 1998-07-16 | 2001-10-02 | Research Development Foundation | DNA-cleaving antitumor agents |
-
1999
- 1999-07-16 US US09/356,303 patent/US6908948B1/en not_active Expired - Fee Related
- 1999-07-16 EP EP99935648A patent/EP1109552A4/en not_active Withdrawn
- 1999-07-16 KR KR1020017000657A patent/KR100763211B1/ko not_active IP Right Cessation
- 1999-07-16 WO PCT/US1999/016171 patent/WO2000003709A1/en not_active Application Discontinuation
- 1999-07-16 RU RU2001104426/15A patent/RU2227029C2/ru not_active IP Right Cessation
- 1999-07-16 CN CNB998098485A patent/CN1243545C/zh not_active Expired - Fee Related
- 1999-07-16 CA CA002337517A patent/CA2337517A1/en not_active Abandoned
- 1999-07-16 NZ NZ509273A patent/NZ509273A/en unknown
- 1999-07-16 IL IL14088499A patent/IL140884A0/xx not_active IP Right Cessation
- 1999-07-16 AU AU51082/99A patent/AU762972B2/en not_active Ceased
- 1999-07-16 JP JP2000559844A patent/JP2002539071A/ja not_active Withdrawn
-
2001
- 2001-01-11 ZA ZA200100353A patent/ZA200100353B/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2002539071A (ja) | 2002-11-19 |
AU5108299A (en) | 2000-02-07 |
NZ509273A (en) | 2003-05-30 |
RU2227029C2 (ru) | 2004-04-20 |
US6908948B1 (en) | 2005-06-21 |
KR20010083116A (ko) | 2001-08-31 |
WO2000003709A1 (en) | 2000-01-27 |
WO2000003709A9 (en) | 2000-07-20 |
AU762972B2 (en) | 2003-07-10 |
CA2337517A1 (en) | 2000-01-27 |
EP1109552A4 (en) | 2007-11-07 |
CN1313766A (zh) | 2001-09-19 |
KR100763211B1 (ko) | 2007-10-08 |
ZA200100353B (en) | 2002-01-10 |
EP1109552A1 (en) | 2001-06-27 |
CN1243545C (zh) | 2006-03-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |