IL140586A - Phenyl ester derivatives of a-amino acid and pharmaceuticals containing them - Google Patents

Phenyl ester derivatives of a-amino acid and pharmaceuticals containing them

Info

Publication number
IL140586A
IL140586A IL14058699A IL14058699A IL140586A IL 140586 A IL140586 A IL 140586A IL 14058699 A IL14058699 A IL 14058699A IL 14058699 A IL14058699 A IL 14058699A IL 140586 A IL140586 A IL 140586A
Authority
IL
Israel
Prior art keywords
acid
amino acid
alkoxy
alkyl
acid phenyl
Prior art date
Application number
IL14058699A
Other languages
English (en)
Hebrew (he)
Other versions
IL140586A0 (en
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of IL140586A0 publication Critical patent/IL140586A0/xx
Publication of IL140586A publication Critical patent/IL140586A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/12—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of acyclic carbon skeletons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL14058699A 1998-07-22 1999-07-16 Phenyl ester derivatives of a-amino acid and pharmaceuticals containing them IL140586A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98305837 1998-07-22
PCT/EP1999/005051 WO2000005196A1 (en) 1998-07-22 1999-07-16 α-AMINO ACID PHENYL ESTER DERIVATIVES

Publications (2)

Publication Number Publication Date
IL140586A0 IL140586A0 (en) 2002-02-10
IL140586A true IL140586A (en) 2004-06-01

Family

ID=8234960

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14058699A IL140586A (en) 1998-07-22 1999-07-16 Phenyl ester derivatives of a-amino acid and pharmaceuticals containing them

Country Status (27)

Country Link
US (1) US6451854B1 (da)
EP (1) EP1098871B1 (da)
JP (1) JP2002521358A (da)
KR (1) KR100599142B1 (da)
CN (1) CN1183101C (da)
AR (1) AR021165A1 (da)
AT (1) ATE244697T1 (da)
AU (1) AU758808B2 (da)
BR (1) BR9912291A (da)
CA (1) CA2337945A1 (da)
CO (1) CO5080742A1 (da)
DE (1) DE69909486T2 (da)
DK (1) DK1098871T3 (da)
ES (1) ES2203163T3 (da)
HU (1) HUP0102705A3 (da)
ID (1) ID27261A (da)
IL (1) IL140586A (da)
NO (1) NO20010280L (da)
NZ (1) NZ509327A (da)
PE (1) PE20000880A1 (da)
PL (1) PL345621A1 (da)
PT (1) PT1098871E (da)
RU (1) RU2223947C2 (da)
SK (1) SK1032001A3 (da)
TR (1) TR200100166T2 (da)
TW (1) TW565546B (da)
WO (1) WO2000005196A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR031473A1 (es) * 2000-11-20 2003-09-24 Lundbeck & Co As H Intensificadores de gaba en el tratamiento de enfermedades relacionadas con una reducida actividad neuroesteroide
JP4043363B2 (ja) 2001-01-19 2008-02-06 ナームローゼ・フエンノートチヤツプ・オルガノン 催眠薬としてのアラニン２，６−ジアルコキシフェニルエステル誘導体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1102011A (en) 1964-05-21 1968-02-07 Richardson Merrell Spa Phenol esters of amino acids
GB1160468A (en) 1967-05-08 1969-08-06 May & Baker Ltd Morpholine Derivative

Also Published As

Publication number Publication date
TW565546B (en) 2003-12-11
CN1183101C (zh) 2005-01-05
ID27261A (id) 2001-03-22
CO5080742A1 (es) 2001-09-25
PT1098871E (pt) 2003-11-28
PL345621A1 (en) 2002-01-02
DK1098871T3 (da) 2003-10-27
TR200100166T2 (tr) 2001-05-21
US6451854B1 (en) 2002-09-17
NZ509327A (en) 2003-04-29
HUP0102705A3 (en) 2002-11-28
DE69909486T2 (de) 2004-05-27
EP1098871A1 (en) 2001-05-16
NO20010280D0 (no) 2001-01-17
WO2000005196A1 (en) 2000-02-03
IL140586A0 (en) 2002-02-10
NO20010280L (no) 2001-03-08
AU5160299A (en) 2000-02-14
PE20000880A1 (es) 2000-09-12
SK1032001A3 (en) 2001-08-06
JP2002521358A (ja) 2002-07-16
DE69909486D1 (de) 2003-08-14
CA2337945A1 (en) 2000-02-03
BR9912291A (pt) 2001-04-17
KR20010071905A (ko) 2001-07-31
ES2203163T3 (es) 2004-04-01
KR100599142B1 (ko) 2006-07-12
HUP0102705A2 (hu) 2001-12-28
RU2223947C2 (ru) 2004-02-20
AR021165A1 (es) 2002-07-03
AU758808B2 (en) 2003-03-27
EP1098871B1 (en) 2003-07-09
ATE244697T1 (de) 2003-07-15
CN1311770A (zh) 2001-09-05

Similar Documents

Publication Publication Date Title
WO1998029409A1 (fr) Sels d'addition acides de compose de piperidine optiquement actif et procede de production associe
EP0116257A1 (en) Process for preparing 4-amino-5-hexenoic acid
EP0894003A1 (en) N-formyl hydroxylamine containing compounds useful as ace inhibitors and/or nep inhibitors
US6451854B1 (en) α-amino acid phenyl ester derivatives
IL109111A (en) HISTORY OF MORPOLIN AND THOMORPOLIN-2 Transformed as GABA-B Antagonists, Preparation and Pharmaceutical Preparations Containing Them
ATE289583T1 (de) Stereoisomere von propyl-isopropylacetamid, verfahren zu deren herstellung sowie diese enthaltende pharmazeutische zubereitungen
AU2002309420B2 (en) New compounds useful in reflux disease
WO2006092204A1 (en) Derivatives of aminobutanoic acid inhibiting cpt
MXPA01000721A (en) &agr;-AMINO ACID PHENYL ESTER DERIVATIVES
CZ2001269A3 (cs) Fenylesterové deriváty alfa-aminokyselin
JP4043363B2 (ja) 催眠薬としてのアラニン２，６−ジアルコキシフェニルエステル誘導体
AU672315B2 (en) Novel processes for preparing (S)-4-amino-hepta-5,6-dienoic acid and intermediates thereof
US20220289668A1 (en) N-formylhydroxylamines as neprilysin (nep) inhibitors, in particular as mixed aminopeptidase n (apn) and neprilysin (nep) inhibitors
JP2002524443A (ja) ピロリジン構造を有するｇａｂａ摂取阻害剤
Nicewonger et al. Mechanistic studies on thiaminase I: 1. The stereochemical course of the reaction
Einhorn et al. Synthesis of a new, C 2 Symmetric α, α-Bis-(Carboxymethyl) Substituted Nitroxide
BR122012005794B1 (pt) processo de síntese racêmica de dois novos análogos do baclofeno

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees