TR200100166T2 - alfa-amino asit fenil ester türevleri - Google Patents

alfa-amino asit fenil ester türevleri

Info

Publication number
TR200100166T2
TR200100166T2 TR2001/00166T TR200100166T TR200100166T2 TR 200100166 T2 TR200100166 T2 TR 200100166T2 TR 2001/00166 T TR2001/00166 T TR 2001/00166T TR 200100166 T TR200100166 T TR 200100166T TR 200100166 T2 TR200100166 T2 TR 200100166T2
Authority
TR
Turkey
Prior art keywords
alkyl
ester derivatives
alkyloxy
alpha
amino acid
Prior art date
Application number
TR2001/00166T
Other languages
English (en)
Inventor
Morton Hamilton Niall
Original Assignee
Akzo Nobel N.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel N.L. filed Critical Akzo Nobel N.L.
Publication of TR200100166T2 publication Critical patent/TR200100166T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/12—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of acyclic carbon skeletons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Bu bulus genel formül I'e sahip alfa-amino asit fenil ester türevleri ile alakalidir, burada R1,(C1-3)alkiloksidir; R2,(C1-3)alkil,(C1-3)alkiloksi veya (C2-3)alkenildir;R3 hidrojen,(C1-3)alkil,(C1-3)alkiloksi veya (C2-3)alkenildir;R4,(C1-6)alkildir; R5 ve R6 bagimsiz olarak, C(1-6)alkil,(C2-6)alkenil,(C2-6)alkinil veya aralkildir ve herbiri seçimlik olarak (C1-3)alkiloksi,(C1-3)alkiloksikarbonil siyano veya NR7R8 in yerine kullanilabilir; R7 ve R8 bagimsiz olarak (C1-6)alkil; veya 2,6-dimetoksifenil 2-(dietilamin)propionat ve 2,6-dimetoksifenil 2-(dietilamin)bütirat disinda bunlarin farmakolojik olarak kabul edilebilir tuzlaridir.Bulus ayrica bahsedilen türevleri ihtiva eden farmakolojik olarak kabul edilmis bilesiklerle ve bu alfa-amino asit fenil ester türevlerinin genel anestesinin baslatilip saglanmasi için uyusturucu olarak kullanilmasi ile de alakalidir.
TR2001/00166T 1998-07-22 1999-07-16 alfa-amino asit fenil ester türevleri TR200100166T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98305837 1998-07-22

Publications (1)

Publication Number Publication Date
TR200100166T2 true TR200100166T2 (tr) 2001-05-21

Family

ID=8234960

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/00166T TR200100166T2 (tr) 1998-07-22 1999-07-16 alfa-amino asit fenil ester türevleri

Country Status (27)

Country Link
US (1) US6451854B1 (tr)
EP (1) EP1098871B1 (tr)
JP (1) JP2002521358A (tr)
KR (1) KR100599142B1 (tr)
CN (1) CN1183101C (tr)
AR (1) AR021165A1 (tr)
AT (1) ATE244697T1 (tr)
AU (1) AU758808B2 (tr)
BR (1) BR9912291A (tr)
CA (1) CA2337945A1 (tr)
CO (1) CO5080742A1 (tr)
DE (1) DE69909486T2 (tr)
DK (1) DK1098871T3 (tr)
ES (1) ES2203163T3 (tr)
HU (1) HUP0102705A3 (tr)
ID (1) ID27261A (tr)
IL (1) IL140586A (tr)
NO (1) NO20010280L (tr)
NZ (1) NZ509327A (tr)
PE (1) PE20000880A1 (tr)
PL (1) PL345621A1 (tr)
PT (1) PT1098871E (tr)
RU (1) RU2223947C2 (tr)
SK (1) SK1032001A3 (tr)
TR (1) TR200100166T2 (tr)
TW (1) TW565546B (tr)
WO (1) WO2000005196A1 (tr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR031473A1 (es) * 2000-11-20 2003-09-24 Lundbeck & Co As H Intensificadores de gaba en el tratamiento de enfermedades relacionadas con una reducida actividad neuroesteroide
EP1373188B1 (en) * 2001-01-19 2006-06-07 Akzo Nobel N.V. Alanine 2,6-dialkoxyphenyl ester derivatives as hypnotics

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1102011A (en) * 1964-05-21 1968-02-07 Richardson Merrell Spa Phenol esters of amino acids
GB1160468A (en) 1967-05-08 1969-08-06 May & Baker Ltd Morpholine Derivative

Also Published As

Publication number Publication date
US6451854B1 (en) 2002-09-17
IL140586A0 (en) 2002-02-10
DK1098871T3 (da) 2003-10-27
EP1098871B1 (en) 2003-07-09
CN1311770A (zh) 2001-09-05
WO2000005196A1 (en) 2000-02-03
BR9912291A (pt) 2001-04-17
TW565546B (en) 2003-12-11
KR100599142B1 (ko) 2006-07-12
EP1098871A1 (en) 2001-05-16
HUP0102705A2 (hu) 2001-12-28
CN1183101C (zh) 2005-01-05
NO20010280L (no) 2001-03-08
ES2203163T3 (es) 2004-04-01
NO20010280D0 (no) 2001-01-17
IL140586A (en) 2004-06-01
AR021165A1 (es) 2002-07-03
AU758808B2 (en) 2003-03-27
HUP0102705A3 (en) 2002-11-28
SK1032001A3 (en) 2001-08-06
ATE244697T1 (de) 2003-07-15
AU5160299A (en) 2000-02-14
JP2002521358A (ja) 2002-07-16
NZ509327A (en) 2003-04-29
CO5080742A1 (es) 2001-09-25
DE69909486D1 (de) 2003-08-14
PE20000880A1 (es) 2000-09-12
PT1098871E (pt) 2003-11-28
PL345621A1 (en) 2002-01-02
CA2337945A1 (en) 2000-02-03
KR20010071905A (ko) 2001-07-31
ID27261A (id) 2001-03-22
DE69909486T2 (de) 2004-05-27
RU2223947C2 (ru) 2004-02-20

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