IL140396A0 - 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives - Google Patents

2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives

Info

Publication number
IL140396A0
IL140396A0 IL14039699A IL14039699A IL140396A0 IL 140396 A0 IL140396 A0 IL 140396A0 IL 14039699 A IL14039699 A IL 14039699A IL 14039699 A IL14039699 A IL 14039699A IL 140396 A0 IL140396 A0 IL 140396A0
Authority
IL
Israel
Prior art keywords
purin
tetrahydrofuran
diol derivatives
diol
derivatives
Prior art date
Application number
IL14039699A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9813538.7A external-priority patent/GB9813538D0/en
Priority claimed from GBGB9909482.3A external-priority patent/GB9909482D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of IL140396A0 publication Critical patent/IL140396A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/06—Heterocyclic radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL14039699A 1998-06-23 1999-06-23 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives IL140396A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9813538.7A GB9813538D0 (en) 1998-06-23 1998-06-23 Chemical compounds
GBGB9909482.3A GB9909482D0 (en) 1999-04-23 1999-04-23 2-(Purin-9-yl)-tetahydrofuran-3,4-diol derivatives
PCT/EP1999/004269 WO1999067265A1 (en) 1998-06-23 1999-06-23 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives

Publications (1)

Publication Number Publication Date
IL140396A0 true IL140396A0 (en) 2002-02-10

Family

ID=26313917

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14039699A IL140396A0 (en) 1998-06-23 1999-06-23 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives

Country Status (27)

Country Link
US (1) US6495528B1 (sh)
EP (1) EP1090022B1 (sh)
JP (1) JP3933870B2 (sh)
KR (1) KR20010071591A (sh)
CN (1) CN1313861A (sh)
AP (1) AP2000002016A0 (sh)
AT (1) ATE246701T1 (sh)
AU (1) AU750462B2 (sh)
BR (1) BR9911482A (sh)
CA (1) CA2335809A1 (sh)
CZ (1) CZ20004868A3 (sh)
DE (1) DE69910213T2 (sh)
EA (1) EA200001224A1 (sh)
EE (1) EE200000768A (sh)
ES (1) ES2204139T3 (sh)
HR (1) HRP20000894A2 (sh)
HU (1) HUP0103025A3 (sh)
ID (1) ID29609A (sh)
IL (1) IL140396A0 (sh)
IS (1) IS5779A (sh)
NO (1) NO20006548L (sh)
NZ (1) NZ509030A (sh)
PL (1) PL345062A1 (sh)
SK (1) SK19542000A3 (sh)
TR (1) TR200100410T2 (sh)
WO (1) WO1999067265A1 (sh)
YU (1) YU81100A (sh)

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AR049384A1 (es) 2004-05-24 2006-07-26 Glaxo Group Ltd Derivados de purina
EP1778712B1 (en) 2004-08-02 2013-01-30 University Of Virginia Patent Foundation 2-propynyl adenosine analogs with modified 5'-ribose groups having a2a agonist activity
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GB0523845D0 (en) * 2005-11-23 2006-01-04 Glaxo Group Ltd Novel salts
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KR20080110925A (ko) 2006-04-21 2008-12-19 노파르티스 아게 아데노신 ａ２ａ 수용체 효능제로서 사용하기 위한 퓨린 유도체
GB0607950D0 (en) 2006-04-21 2006-05-31 Novartis Ag Organic compounds
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PL2231642T3 (pl) 2008-01-11 2014-04-30 Novartis Ag Pirymidyny jako inhibitory kinazy
PT2391366E (pt) 2009-01-29 2013-02-05 Novartis Ag Benzimidazoles substituídos para o tratamento de astrocitomas
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
EP2464649A1 (en) 2009-08-12 2012-06-20 Novartis AG Heterocyclic hydrazone compounds and their uses to treat cancer and inflammation
NZ598220A (en) 2009-08-17 2014-02-28 Intellikine Llc Heterocyclic compounds and uses thereof
CA2771432A1 (en) 2009-08-20 2011-02-24 Novartis Ag Heterocyclic oxime compounds
UY33597A (es) 2010-09-09 2012-04-30 Irm Llc Compuestos y composiciones como inhibidores de la trk
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JP2014505088A (ja) 2011-02-10 2014-02-27 ノバルティス アーゲー Ｃ−ＭＥＴチロシンキナーゼ阻害剤としての［１，２，４］トリアゾロ［４，３−ｂ］ピリダジン化合物
JP5808826B2 (ja) 2011-02-23 2015-11-10 インテリカイン， エルエルシー 複素環化合物およびその使用
US9102671B2 (en) 2011-02-25 2015-08-11 Novartis Ag Compounds and compositions as TRK inhibitors
UY34329A (es) 2011-09-15 2013-04-30 Novartis Ag Compuestos de triazolopiridina
US9174994B2 (en) 2011-11-23 2015-11-03 Intellikine, Llc Enhanced treatment regimens using mTor inhibitors
CN104245701A (zh) 2012-04-03 2014-12-24 诺华有限公司 有酪氨酸激酶抑制剂的组合产品和其应用
EP2968340A4 (en) 2013-03-15 2016-08-10 Intellikine Llc COMBINING KINASE INHIBITORS AND USES THEREOF
TW201605450A (zh) 2013-12-03 2016-02-16 諾華公司 Ｍｄｍ２抑制劑與ＢＲＡＦ抑制劑之組合及其用途
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Also Published As

Publication number Publication date
HUP0103025A3 (en) 2002-04-29
DE69910213D1 (de) 2003-09-11
AP2000002016A0 (en) 2000-12-31
CA2335809A1 (en) 1999-12-29
EP1090022B1 (en) 2003-08-06
ATE246701T1 (de) 2003-08-15
EP1090022A1 (en) 2001-04-11
CZ20004868A3 (cs) 2001-08-15
JP2002518512A (ja) 2002-06-25
EE200000768A (et) 2002-04-15
JP3933870B2 (ja) 2007-06-20
NO20006548D0 (no) 2000-12-21
BR9911482A (pt) 2002-01-22
US6495528B1 (en) 2002-12-17
EA200001224A1 (ru) 2001-08-27
NO20006548L (no) 2001-02-22
IS5779A (is) 2000-12-19
KR20010071591A (ko) 2001-07-28
PL345062A1 (en) 2001-11-19
ID29609A (id) 2001-09-06
SK19542000A3 (sk) 2001-09-11
DE69910213T2 (de) 2004-07-01
YU81100A (sh) 2003-10-31
AU750462B2 (en) 2002-07-18
WO1999067265A1 (en) 1999-12-29
HUP0103025A2 (hu) 2001-12-28
NZ509030A (en) 2003-07-25
HRP20000894A2 (en) 2001-12-31
ES2204139T3 (es) 2004-04-16
TR200100410T2 (tr) 2001-06-21
CN1313861A (zh) 2001-09-19
AU4774499A (en) 2000-01-10

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