IL139969A0 - A pharmaceutical formulation for insulin-like growth factor and insulin like growth factor binding protein - Google Patents

A pharmaceutical formulation for insulin-like growth factor and insulin like growth factor binding protein

Info

Publication number
IL139969A0
IL139969A0 IL13996999A IL13996999A IL139969A0 IL 139969 A0 IL139969 A0 IL 139969A0 IL 13996999 A IL13996999 A IL 13996999A IL 13996999 A IL13996999 A IL 13996999A IL 139969 A0 IL139969 A0 IL 139969A0
Authority
IL
Israel
Prior art keywords
insulin
growth factor
binding protein
pharmaceutical formulation
igfbp
Prior art date
Application number
IL13996999A
Other languages
English (en)
Original Assignee
Celtrix Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celtrix Pharma filed Critical Celtrix Pharma
Publication of IL139969A0 publication Critical patent/IL139969A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
IL13996999A 1998-06-01 1999-05-28 A pharmaceutical formulation for insulin-like growth factor and insulin like growth factor binding protein IL139969A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/089,062 US6436897B2 (en) 1998-06-01 1998-06-01 Pharmaceutical formulations for IGF/IGFBP
PCT/US1999/012173 WO1999062536A2 (en) 1998-06-01 1999-05-28 Pharmaceutical formulations for igf/igfbp

Publications (1)

Publication Number Publication Date
IL139969A0 true IL139969A0 (en) 2002-02-10

Family

ID=22215473

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13996999A IL139969A0 (en) 1998-06-01 1999-05-28 A pharmaceutical formulation for insulin-like growth factor and insulin like growth factor binding protein

Country Status (14)

Country Link
US (2) US6436897B2 (zh)
EP (1) EP1082133B1 (zh)
JP (1) JP2002516871A (zh)
KR (1) KR20010052500A (zh)
CN (1) CN1201816C (zh)
AT (1) ATE270898T1 (zh)
AU (1) AU4326799A (zh)
BR (1) BR9910863A (zh)
CA (1) CA2330925C (zh)
DE (1) DE69918690T2 (zh)
ES (1) ES2221456T3 (zh)
HK (1) HK1040637B (zh)
IL (1) IL139969A0 (zh)
WO (1) WO1999062536A2 (zh)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6040292A (en) * 1999-06-04 2000-03-21 Celtrix Pharmaceuticals, Inc. Methods for treating diabetes
AUPR030900A0 (en) 2000-09-22 2000-10-12 Queensland University Of Technology Growth factor complex
ES2180416B1 (es) * 2001-03-12 2004-06-01 BIOTOOLS BIOTECHNOLOGICAL & MEDICAL LABORATORIES, S.A. Procedimiento para la preparacion de mezclas de reaccion estabilizadas, total o parcialmente desecadas, que comprenden, al menos, una enzima, mezclas de reaccion y kits que las contienen.
US20040121407A1 (en) * 2002-09-06 2004-06-24 Elixir Pharmaceuticals, Inc. Regulation of the growth hormone/IGF-1 axis
US20100143442A1 (en) 2003-02-05 2010-06-10 Queensland University Of Technology Growth factor complexes and modulation of cell migration and growth
AU2003900481A0 (en) 2003-02-05 2003-02-20 Queensland University Of Technology Synthetic modulators of cell migration and growth
AU2003903896A0 (en) 2003-07-28 2003-08-07 Queensland University Of Technology Skin regeneration system
BRPI0514411B8 (pt) 2004-08-17 2021-05-25 Regeneron Pharma formulação, e, método de produzir uma formulação
EP1674113A1 (en) 2004-12-22 2006-06-28 F. Hoffmann-La Roche Ag Conjugates of insulin-like growth factor-1 (IGF-1) and poly(ethylene glycol)
ATE459637T1 (de) * 2004-12-24 2010-03-15 Insmed Inc Gereinigte rhigf-i/rhigfbp-3-komplexe und herstellungsverfahren dafür
CN101107022B (zh) * 2005-01-25 2013-07-17 辉瑞爱尔兰药品合伙公司 用于渗滤的方法
LT2586459T (lt) * 2005-03-25 2017-09-25 Regeneron Pharmaceuticals, Inc. Vegf antagonisto kompozicijos
BRPI0611901A2 (pt) 2005-06-14 2012-08-28 Amgen, Inc composição, liofilizado, kit, e, processo para preparar uma composição
ES2406764T3 (es) 2006-06-16 2013-06-10 Regeneron Pharmaceuticals, Inc. Formulaciones que comprenden antagonistas de VEGF para administración intravítrea
JP4958975B2 (ja) 2006-08-31 2012-06-20 エフ．ホフマン−ラ ロシュ アーゲー インスリン様増殖因子ｉの製造方法
CL2007002502A1 (es) 2006-08-31 2008-05-30 Hoffmann La Roche Variantes del factor de crecimiento similar a insulina-1 humano (igf-1) pegilados en lisina; metodo de produccion; proteina de fusion que la comprende; y su uso para tratar la enfermedad de alzheimer.
CN101998965B (zh) 2007-11-01 2014-03-12 安斯泰来制药有限公司 免疫抑制性多肽与核酸
EP2352514A4 (en) 2008-10-29 2012-07-25 Univ Rockefeller METHOD AND KIT FOR DISEASE TREATMENT BY ADMINISTRATION OF THE PROTEIN BINDING TO AN INSULINARY GROWTH FACTOR 2
EP2507261B1 (en) 2009-11-30 2016-12-21 Factor Therapeutics Limited Fibronectin: growth factor chimeras
US20110152188A1 (en) * 2009-12-23 2011-06-23 Hanns-Christian Mahler Pharmaceutical compositions of igf/i proteins
JO3283B1 (ar) 2011-04-26 2018-09-16 Sanofi Sa تركيب يتضمن أفليبيرسيبت, حمض فولينيك, 5- فلورويوراسيل (5- Fu) وإرينوسيتان (FOLFIRI)
US11035764B2 (en) * 2012-02-03 2021-06-15 Charm Sciences, Inc. Extraction of mycotoxins
US20190293527A1 (en) * 2013-02-04 2019-09-26 Charm Sciences, Inc. Extraction of mycotoxins
TWI698253B (zh) 2012-09-07 2020-07-11 美商柯赫勒斯生物科學有限公司 阿達木單抗（ａｄａｌｉｍｕｍａｂ）之穩定水性調配物
EA035674B1 (ru) 2014-07-18 2020-07-24 Санофи Способ определения того, является ли пациент, предположительно страдающий от рака, кандидатом для терапии афлиберцептом
US20180188139A1 (en) * 2015-06-22 2018-07-05 Dots Technology Corp. Improved assays and methods for allergen detection
US11229702B1 (en) 2015-10-28 2022-01-25 Coherus Biosciences, Inc. High concentration formulations of adalimumab
CA3007276C (en) 2015-12-03 2021-12-28 Regeneron Pharmaceuticals, Inc. Use of vegf inhibitor to treat macular degeneration in a patient population
CN108699127A (zh) * 2015-12-31 2018-10-23 西门子医疗保健诊断公司 非重组人胰岛素-样生长因子结合蛋白浓缩物
US11071782B2 (en) 2016-04-20 2021-07-27 Coherus Biosciences, Inc. Method of filling a container with no headspace
JP2019534263A (ja) 2016-10-07 2019-11-28 リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 室温で安定な凍結乾燥タンパク質
AU2017345490B2 (en) 2016-10-21 2022-07-07 Amgen Inc. Pharmaceutical formulations and methods of making the same
US20230381285A1 (en) * 2020-10-19 2023-11-30 Oak Hill Bio Ltd Compositions suitable for use in neonates
WO2023139250A1 (en) * 2022-01-24 2023-07-27 Oak Hill Bio Limited Lot release assays for igf‐1/igfbp complexes

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681814A (en) 1990-06-07 1997-10-28 Genentech, Inc. Formulated IGF-I Composition
US5187151A (en) * 1991-02-12 1993-02-16 Genentech, Inc. Use of binding protein with igf-i as an anabolic growth promoting agent
US5643867A (en) * 1992-08-26 1997-07-01 Celtrix Pharmaceuticals, Inc. Method for treating catabolic conditions
US5563046A (en) 1993-08-02 1996-10-08 Celtrix Pharmaceuticals, Inc. Fusion polypeptides and proteins
ATE297214T1 (de) 1993-09-20 2005-06-15 Celtrix Pharma Behandlung von immunologischen und hematologischen störungen mit igfbp allein oder als komplex mit igf
CA2176708A1 (en) 1993-11-15 1995-05-26 Christopher A. Maack Method of treating neurological disorders
CA2176709A1 (en) * 1993-11-15 1995-05-26 Howard R. Higley Method of treating renal disease by administering igf-i and igfbp-3
US5861273A (en) 1993-12-21 1999-01-19 Celtrix Phamraceuticals, Inc. Chromosomal expression of heterologous genes in bacterial cells
US5789547A (en) 1995-06-07 1998-08-04 Celtrix Pharmaceuticals, Inc. Method of producing insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) with correct folding and disulfide bonding
SE9502927D0 (sv) * 1995-08-24 1995-08-24 Pharmacia Ab Solution containing IGF-I
US5948757A (en) * 1996-03-01 1999-09-07 Celtrix Pharmaceuticals, Inc. High dose IGF-1 therapy
US5783556A (en) 1996-08-13 1998-07-21 Genentech, Inc. Formulated insulin-containing composition

Also Published As

Publication number Publication date
DE69918690D1 (de) 2004-08-19
BR9910863A (pt) 2002-06-11
ES2221456T3 (es) 2004-12-16
WO1999062536A2 (en) 1999-12-09
EP1082133A2 (en) 2001-03-14
CN1315868A (zh) 2001-10-03
HK1040637A1 (en) 2002-06-21
US6436897B2 (en) 2002-08-20
CA2330925C (en) 2010-02-09
ATE270898T1 (de) 2004-07-15
US20020004478A1 (en) 2002-01-10
CN1201816C (zh) 2005-05-18
DE69918690T2 (de) 2005-08-18
WO1999062536A3 (en) 2000-03-30
AU4326799A (en) 1999-12-20
JP2002516871A (ja) 2002-06-11
HK1040637B (zh) 2006-01-06
CA2330925A1 (en) 1999-12-09
US20030087806A1 (en) 2003-05-08
KR20010052500A (ko) 2001-06-25
EP1082133B1 (en) 2004-07-14

Similar Documents

Publication Publication Date Title
IL139969A0 (en) A pharmaceutical formulation for insulin-like growth factor and insulin like growth factor binding protein
CA2356257A1 (en) Insulin-like growth factor (igf) i mutant variants
HUP9902476A3 (en) A pharmaceutical formulation containing growth hormone, an amino acid and a non-ionic detergent
HK1098963A1 (en) Preparations stabilized over long time
TW397687B (en) Stable freeze-dried formulation comprising a protein; assay kit
WO1998040401A3 (en) Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics
WO1998045427A3 (en) Insulin-like growth factor agonist peptides
ZA976598B (en) IGF-I and insulin formulation
NZ294743A (en) A formulation for administering transdermally a protein or polypeptide such as insulin
PH25618A (en) Stabilised human protein preparation
AU5956398A (en) Remedies for lymphocytic tumors
GB9803448D0 (en) Pharmaceutical formulation
WO2000078801A3 (en) Insulin-like growth factor agonist molecules
HUP0202189A2 (en) Growth hormone formulations, method for their preparation and device and kit comprising thereof
GR3034309T3 (en) IFN--g(b) LIQUID FORMULATIONS
EP0783521B8 (en) Polypeptide compounds containing d-2-alkyltryptophan capable of promoting the release of growth hormone
EP0855181A3 (en) Medicament or nutritional formulation for immune-modulation with amino acids
AU5926400A (en) Antimicrobial artificial nail composition and methods for preparing and using same
WO1994016723A3 (en) Wound healing composition
AU9005291A (en) Avian growth hormone receptor and binding protein
SI0918536T1 (en) Composition comprising insulin and insulin-like growth factor-i (igf-i)
AU3179799A (en) Use of growth hormone binding protein with a nuclear localization sequence (nls-ghbp)
AU2142601A (en) Novel polypeptide---the growth hormone protein family 10 and polynucleotide encoding it
AUPM375994A0 (en) Stabilised growth hormone formulation
CA2315241A1 (en) Protein rim2