KR20010052500A - 인슐린 유사 성장 인자/인슐린 유사 성장 인자 결합단백질의 의약조성물 - Google Patents
인슐린 유사 성장 인자/인슐린 유사 성장 인자 결합단백질의 의약조성물 Download PDFInfo
- Publication number
- KR20010052500A KR20010052500A KR1020007013631A KR20007013631A KR20010052500A KR 20010052500 A KR20010052500 A KR 20010052500A KR 1020007013631 A KR1020007013631 A KR 1020007013631A KR 20007013631 A KR20007013631 A KR 20007013631A KR 20010052500 A KR20010052500 A KR 20010052500A
- Authority
- KR
- South Korea
- Prior art keywords
- insulin
- growth factor
- pharmaceutical composition
- binding protein
- composition according
- Prior art date
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- 108091022911 insulin-like growth factor binding Proteins 0.000 title claims abstract description 51
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/089,062 US6436897B2 (en) | 1998-06-01 | 1998-06-01 | Pharmaceutical formulations for IGF/IGFBP |
| US09/089,062 | 1998-06-01 | ||
| PCT/US1999/012173 WO1999062536A2 (en) | 1998-06-01 | 1999-05-28 | Pharmaceutical formulations for igf/igfbp |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20010052500A true KR20010052500A (ko) | 2001-06-25 |
Family
ID=22215473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020007013631A KR20010052500A (ko) | 1998-06-01 | 1999-05-28 | 인슐린 유사 성장 인자/인슐린 유사 성장 인자 결합단백질의 의약조성물 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US6436897B2 (zh) |
| EP (1) | EP1082133B1 (zh) |
| JP (1) | JP2002516871A (zh) |
| KR (1) | KR20010052500A (zh) |
| CN (1) | CN1201816C (zh) |
| AT (1) | ATE270898T1 (zh) |
| AU (1) | AU4326799A (zh) |
| BR (1) | BR9910863A (zh) |
| CA (1) | CA2330925C (zh) |
| DE (1) | DE69918690T2 (zh) |
| ES (1) | ES2221456T3 (zh) |
| HK (1) | HK1040637B (zh) |
| IL (1) | IL139969A0 (zh) |
| WO (1) | WO1999062536A2 (zh) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6040292A (en) * | 1999-06-04 | 2000-03-21 | Celtrix Pharmaceuticals, Inc. | Methods for treating diabetes |
| AUPR030900A0 (en) | 2000-09-22 | 2000-10-12 | Queensland University Of Technology | Growth factor complex |
| ES2180416B1 (es) * | 2001-03-12 | 2004-06-01 | BIOTOOLS BIOTECHNOLOGICAL & MEDICAL LABORATORIES, S.A. | Procedimiento para la preparacion de mezclas de reaccion estabilizadas, total o parcialmente desecadas, que comprenden, al menos, una enzima, mezclas de reaccion y kits que las contienen. |
| US20140186361A1 (en) | 2012-09-07 | 2014-07-03 | Coherus Biosciences, Inc. | Stable Aqueous Formulations of Adalimumab |
| US20040121407A1 (en) * | 2002-09-06 | 2004-06-24 | Elixir Pharmaceuticals, Inc. | Regulation of the growth hormone/IGF-1 axis |
| US20100143442A1 (en) | 2003-02-05 | 2010-06-10 | Queensland University Of Technology | Growth factor complexes and modulation of cell migration and growth |
| AU2003900481A0 (en) | 2003-02-05 | 2003-02-20 | Queensland University Of Technology | Synthetic modulators of cell migration and growth |
| AU2003903896A0 (en) | 2003-07-28 | 2003-08-07 | Queensland University Of Technology | Skin regeneration system |
| AU2005277357B2 (en) | 2004-08-17 | 2011-08-04 | Regeneron Pharmaceuticals, Inc. | IL-1 antagonist formulations |
| EP1674113A1 (en) | 2004-12-22 | 2006-06-28 | F. Hoffmann-La Roche Ag | Conjugates of insulin-like growth factor-1 (IGF-1) and poly(ethylene glycol) |
| ATE459637T1 (de) * | 2004-12-24 | 2010-03-15 | Insmed Inc | Gereinigte rhigf-i/rhigfbp-3-komplexe und herstellungsverfahren dafür |
| RU2442822C2 (ru) * | 2005-01-25 | 2012-02-20 | Вайет Рисерч Айрлэнд Лимитед | Вещества, защищающие клетки от рассечения при сборе микрофильтрацией |
| PL1861116T3 (pl) * | 2005-03-25 | 2016-02-29 | Regeneron Pharma | Formulacje antagonistów VEGF |
| EP3673919A1 (en) | 2005-06-14 | 2020-07-01 | Amgen Inc. | Self-buffering protein formulations |
| CN101478949A (zh) | 2006-06-16 | 2009-07-08 | 瑞泽恩制药公司 | 适合玻璃体内施用的vegf拮抗剂的制剂 |
| AU2007291501B2 (en) | 2006-08-31 | 2012-07-12 | F. Hoffmann-La Roche Ag | Method for the production of insulin-like growth factor-I |
| CL2007002502A1 (es) | 2006-08-31 | 2008-05-30 | Hoffmann La Roche | Variantes del factor de crecimiento similar a insulina-1 humano (igf-1) pegilados en lisina; metodo de produccion; proteina de fusion que la comprende; y su uso para tratar la enfermedad de alzheimer. |
| EP2612868B1 (en) | 2007-11-01 | 2018-08-15 | Astellas Pharma Inc. | Immunosuppressive polypeptides and nucleic acids |
| WO2010096125A1 (en) * | 2008-10-29 | 2010-08-26 | The Rockefeller University | Methods and kits for treating disease by administering insulin-like growth factor binding protein-2 |
| NZ600454A (en) | 2009-11-30 | 2014-10-31 | Univ Queensland | Fibronectin: growth factor chimeras |
| US20110152188A1 (en) * | 2009-12-23 | 2011-06-23 | Hanns-Christian Mahler | Pharmaceutical compositions of igf/i proteins |
| JO3283B1 (ar) | 2011-04-26 | 2018-09-16 | Sanofi Sa | تركيب يتضمن أفليبيرسيبت, حمض فولينيك, 5- فلورويوراسيل (5- Fu) وإرينوسيتان (FOLFIRI) |
| WO2013116847A1 (en) * | 2012-02-03 | 2013-08-08 | Charm Sciences, Inc. | Extraction of mycotoxins |
| US20190293527A1 (en) * | 2013-02-04 | 2019-09-26 | Charm Sciences, Inc. | Extraction of mycotoxins |
| MA40354A (fr) | 2014-07-18 | 2017-05-24 | Sanofi Sa | Procédé permettant de prédire le résultat d'un traitement avec de l'aflibercept d'un patient suspecté de souffrir d'un cancer |
| WO2016209773A1 (en) * | 2015-06-22 | 2016-12-29 | Dots Technology Corp. | Improved assays and methods for allergen detection |
| US11229702B1 (en) | 2015-10-28 | 2022-01-25 | Coherus Biosciences, Inc. | High concentration formulations of adalimumab |
| CA3007276C (en) | 2015-12-03 | 2021-12-28 | Regeneron Pharmaceuticals, Inc. | Use of vegf inhibitor to treat macular degeneration in a patient population |
| WO2017117236A1 (en) * | 2015-12-31 | 2017-07-06 | Siemens Healthcare Diagnostics Inc. | Non-recombinant human insulin-like growth factor binding protein concentrate |
| WO2017184880A1 (en) | 2016-04-20 | 2017-10-26 | Coherus Biosciences, Inc. | A method of filling a container with no headspace |
| EP3522867A1 (en) | 2016-10-07 | 2019-08-14 | Regeneron Pharmaceuticals, Inc. | Room temperature stable lyophilized protein |
| JP6884858B2 (ja) | 2016-10-21 | 2021-06-09 | アムジエン・インコーポレーテツド | 医薬製剤及びその製造方法 |
| CA3194764A1 (en) * | 2020-10-19 | 2022-04-28 | Oak Hill Bio Limited | Compositions suitable for use in neonates |
| WO2023139250A1 (en) * | 2022-01-24 | 2023-07-27 | Oak Hill Bio Limited | Lot release assays for igf‐1/igfbp complexes |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5681814A (en) | 1990-06-07 | 1997-10-28 | Genentech, Inc. | Formulated IGF-I Composition |
| US5187151A (en) * | 1991-02-12 | 1993-02-16 | Genentech, Inc. | Use of binding protein with igf-i as an anabolic growth promoting agent |
| US5643867A (en) * | 1992-08-26 | 1997-07-01 | Celtrix Pharmaceuticals, Inc. | Method for treating catabolic conditions |
| US5563046A (en) | 1993-08-02 | 1996-10-08 | Celtrix Pharmaceuticals, Inc. | Fusion polypeptides and proteins |
| EP0726911B1 (en) | 1993-09-20 | 2002-10-30 | Celtrix Pharmaceuticals, Inc. | Treatment of hematologic disorders with a igf-1/igfbp-3 complex |
| JPH09509140A (ja) | 1993-11-15 | 1997-09-16 | セルトリックス ファーマシューティカルズ，インコーポレイテッド | 神経学的障害の治療方法 |
| EP0732933B1 (en) * | 1993-11-15 | 2002-10-09 | Celtrix Pharmaceuticals, Inc. | Use of igf-1 and igfbp-3 in the manufacture of a medicament for treating a renal disorder |
| US5861273A (en) | 1993-12-21 | 1999-01-19 | Celtrix Phamraceuticals, Inc. | Chromosomal expression of heterologous genes in bacterial cells |
| US5789547A (en) | 1995-06-07 | 1998-08-04 | Celtrix Pharmaceuticals, Inc. | Method of producing insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) with correct folding and disulfide bonding |
| SE9502927D0 (sv) * | 1995-08-24 | 1995-08-24 | Pharmacia Ab | Solution containing IGF-I |
| US5948757A (en) * | 1996-03-01 | 1999-09-07 | Celtrix Pharmaceuticals, Inc. | High dose IGF-1 therapy |
| US5783556A (en) | 1996-08-13 | 1998-07-21 | Genentech, Inc. | Formulated insulin-containing composition |
-
1998
- 1998-06-01 US US09/089,062 patent/US6436897B2/en not_active Expired - Lifetime
-
1999
- 1999-05-28 IL IL13996999A patent/IL139969A0/xx unknown
- 1999-05-28 AU AU43267/99A patent/AU4326799A/en not_active Abandoned
- 1999-05-28 BR BR9910863-1A patent/BR9910863A/pt not_active Application Discontinuation
- 1999-05-28 DE DE69918690T patent/DE69918690T2/de not_active Expired - Lifetime
- 1999-05-28 ES ES99955220T patent/ES2221456T3/es not_active Expired - Lifetime
- 1999-05-28 JP JP2000551792A patent/JP2002516871A/ja active Pending
- 1999-05-28 KR KR1020007013631A patent/KR20010052500A/ko not_active Application Discontinuation
- 1999-05-28 CA CA2330925A patent/CA2330925C/en not_active Expired - Lifetime
- 1999-05-28 CN CNB998091863A patent/CN1201816C/zh not_active Expired - Fee Related
- 1999-05-28 EP EP99955220A patent/EP1082133B1/en not_active Expired - Lifetime
- 1999-05-28 AT AT99955220T patent/ATE270898T1/de active
- 1999-05-28 WO PCT/US1999/012173 patent/WO1999062536A2/en active IP Right Grant
-
2002
- 2002-03-28 HK HK02102400.8A patent/HK1040637B/zh not_active IP Right Cessation
- 2002-08-20 US US10/223,682 patent/US20030087806A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20030087806A1 (en) | 2003-05-08 |
| WO1999062536A2 (en) | 1999-12-09 |
| ES2221456T3 (es) | 2004-12-16 |
| WO1999062536A3 (en) | 2000-03-30 |
| EP1082133A2 (en) | 2001-03-14 |
| US20020004478A1 (en) | 2002-01-10 |
| EP1082133B1 (en) | 2004-07-14 |
| DE69918690T2 (de) | 2005-08-18 |
| CN1201816C (zh) | 2005-05-18 |
| JP2002516871A (ja) | 2002-06-11 |
| CA2330925A1 (en) | 1999-12-09 |
| CA2330925C (en) | 2010-02-09 |
| IL139969A0 (en) | 2002-02-10 |
| BR9910863A (pt) | 2002-06-11 |
| HK1040637A1 (en) | 2002-06-21 |
| AU4326799A (en) | 1999-12-20 |
| ATE270898T1 (de) | 2004-07-15 |
| HK1040637B (zh) | 2006-01-06 |
| US6436897B2 (en) | 2002-08-20 |
| CN1315868A (zh) | 2001-10-03 |
| DE69918690D1 (de) | 2004-08-19 |
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