IL139872A0 - Derivatives of 3-(2-oxo-[1,3'] bipyrrolidinyl-3-ylidenemethyl) cephems - Google Patents

Derivatives of 3-(2-oxo-[1,3'] bipyrrolidinyl-3-ylidenemethyl) cephems

Info

Publication number
IL139872A0
IL139872A0 IL13987299A IL13987299A IL139872A0 IL 139872 A0 IL139872 A0 IL 139872A0 IL 13987299 A IL13987299 A IL 13987299A IL 13987299 A IL13987299 A IL 13987299A IL 139872 A0 IL139872 A0 IL 139872A0
Authority
IL
Israel
Prior art keywords
bipyrrolidinyl
cephems
ylidenemethyl
oxo
derivatives
Prior art date
Application number
IL13987299A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL139872A0 publication Critical patent/IL139872A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/48—Methylene radicals, substituted by hetero rings
    • C07D501/56—Methylene radicals, substituted by hetero rings with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL13987299A 1998-06-15 1999-06-07 Derivatives of 3-(2-oxo-[1,3'] bipyrrolidinyl-3-ylidenemethyl) cephems IL139872A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98110888 1998-06-15
EP98117099 1998-09-10
PCT/EP1999/003907 WO1999065920A1 (en) 1998-06-15 1999-06-07 Derivatives of 3-(2-oxo-[1,3']bipyrrolidinyl-3-ylidenemethyl)-cephems

Publications (1)

Publication Number Publication Date
IL139872A0 true IL139872A0 (en) 2002-02-10

Family

ID=26149347

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13987299A IL139872A0 (en) 1998-06-15 1999-06-07 Derivatives of 3-(2-oxo-[1,3'] bipyrrolidinyl-3-ylidenemethyl) cephems

Country Status (28)

Country Link
EP (1) EP1087980B1 (de)
JP (1) JP3872955B2 (de)
KR (1) KR100411915B1 (de)
CN (1) CN1136222C (de)
AR (1) AR018675A1 (de)
AT (1) ATE231871T1 (de)
AU (1) AU754732B2 (de)
BE (1) BE2014C034I2 (de)
BR (2) BRPI9911178B8 (de)
CA (1) CA2334568C (de)
CO (1) CO5080758A1 (de)
DE (1) DE69905162T2 (de)
DK (1) DK1087980T3 (de)
ES (1) ES2190222T3 (de)
FR (1) FR14C0044I2 (de)
GT (1) GT199900084A (de)
HU (1) HUP0105426A3 (de)
ID (1) ID27686A (de)
IL (1) IL139872A0 (de)
LU (1) LU92564I2 (de)
MA (1) MA26650A1 (de)
NO (1) NO20006350L (de)
PA (1) PA8475701A1 (de)
PE (1) PE20000645A1 (de)
PL (1) PL344994A1 (de)
SV (1) SV1999000075A (de)
TN (1) TNSN99114A1 (de)
WO (1) WO1999065920A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6267100A (en) * 1999-07-07 2001-01-30 F. Hoffmann-La Roche Ag Vinylpyrrolidinone derivatives with substituted thiazole ring
DK1148140T3 (da) 2000-04-19 2007-01-08 Basilea Pharmaceutica Ag Fremgangsmåde til fremstilling af D-asparaginderivater
US6504025B2 (en) * 2000-05-24 2003-01-07 Basilea Pharmaceutica Ag Process for the preparation of vinyl-pyrrolidinone cephalosporin derivatives
ATE440101T1 (de) 2003-03-27 2009-09-15 Basilea Pharmaceutica Ag Cephalosporin in kristalliner form
EP1656930A1 (de) 2004-11-10 2006-05-17 Basilea Pharmaceutica AG Stabilisierte gefriergetrocknete Formulierung für Cephalosporinderivate
AR071318A1 (es) 2008-04-15 2010-06-09 Basilea Pharmaceutica Ag Benzhidril ester del acido (6r,7r)-7-{2-(5-amino-[1,2,4]tiadiazol-3-il)-2-[(z)-tritiloxiimino]-acetilamino}-3-[(r)-1'-terc-butoxicarbonil-2-oxo-[1,3']bipirrolidinil-(3e)-ilidenometil]-8-oxo-5-tia-1-aza-biciclo[4.2.0]oct-2-eno-2-carboxilico cristalino; su elaboracion y uso
WO2010072672A1 (en) 2008-12-24 2010-07-01 Basilea Pharmaceutica Ag New crystal polymorphs of ceftobiprole
EP2435442B1 (de) * 2009-05-25 2016-01-13 Sandoz AG Verfahren zur herstellung von ceftobiprol medocaril
PL2569321T3 (pl) 2010-05-10 2015-07-31 Basilea Pharmaceutica Int Ltd Sposób utleniania do otrzymywania pochodnych 3-formylo-cefemu

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0841339T3 (da) * 1996-11-06 2007-07-02 Basilea Pharmaceutica Ag Vinylpyrrolidinon-cephalosporinderivater
TW415949B (en) * 1996-12-19 2000-12-21 Hoffmann La Roche Vinyl pyrrolidine cephalosporin derivatives with basic substituents

Also Published As

Publication number Publication date
BRPI9911178B8 (pt) 2017-03-07
EP1087980A1 (de) 2001-04-04
PA8475701A1 (es) 2000-09-29
FR14C0044I1 (de) 2014-07-18
CO5080758A1 (es) 2001-09-25
CN1136222C (zh) 2004-01-28
PE20000645A1 (es) 2000-07-26
PL344994A1 (en) 2001-11-19
BE2014C034I2 (en) 2018-08-24
ES2190222T3 (es) 2003-07-16
BR9911178B1 (pt) 2013-10-29
EP1087980B1 (de) 2003-01-29
WO1999065920A1 (en) 1999-12-23
HUP0105426A2 (hu) 2002-05-29
JP2002518401A (ja) 2002-06-25
AU754732B2 (en) 2002-11-21
KR20010052866A (ko) 2001-06-25
MA26650A1 (fr) 2004-12-20
CA2334568C (en) 2009-02-24
JP3872955B2 (ja) 2007-01-24
GT199900084A (es) 2000-12-05
ID27686A (id) 2001-04-19
NO20006350D0 (no) 2000-12-13
CN1305484A (zh) 2001-07-25
DK1087980T3 (da) 2003-05-26
KR100411915B1 (ko) 2003-12-18
AR018675A1 (es) 2001-11-28
BRPI9911178C1 (pt) 2021-05-25
FR14C0044I2 (fr) 2015-02-20
CA2334568A1 (en) 1999-12-23
AU4508199A (en) 2000-01-05
LU92564I2 (fr) 2014-12-01
DE69905162T2 (de) 2003-12-24
HUP0105426A3 (en) 2002-12-28
BR9911178A (pt) 2001-03-13
ATE231871T1 (de) 2003-02-15
DE69905162D1 (de) 2003-03-06
NO20006350L (no) 2000-12-13
TNSN99114A1 (fr) 2005-11-10
SV1999000075A (es) 2000-05-02

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