IL139241A0 - Meiosis regulating compounds - Google Patents

Meiosis regulating compounds

Info

Publication number
IL139241A0
IL139241A0 IL13924199A IL13924199A IL139241A0 IL 139241 A0 IL139241 A0 IL 139241A0 IL 13924199 A IL13924199 A IL 13924199A IL 13924199 A IL13924199 A IL 13924199A IL 139241 A0 IL139241 A0 IL 139241A0
Authority
IL
Israel
Prior art keywords
regulating compounds
meiosis regulating
meiosis
compounds
regulating
Prior art date
Application number
IL13924199A
Other languages
English (en)
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP98250166A external-priority patent/EP0957108A1/en
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Priority claimed from PCT/DK1999/000263 external-priority patent/WO1999058549A1/en
Publication of IL139241A0 publication Critical patent/IL139241A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Steroid Compounds (AREA)
IL13924199A 1998-05-13 1999-05-11 Meiosis regulating compounds IL139241A0 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DK65798 1998-05-13
EP98250166A EP0957108A1 (en) 1998-05-14 1998-05-14 Unsaturated cholestane derivatives, pharmaceutical compositions comprising them and use of these derivatives for the preparation of meiosis regulating medicaments
US8630698P 1998-05-21 1998-05-21
DK81198 1998-06-19
US9298398P 1998-07-16 1998-07-16
PCT/DK1999/000263 WO1999058549A1 (en) 1998-05-13 1999-05-11 Meiosis regulating compounds

Publications (1)

Publication Number Publication Date
IL139241A0 true IL139241A0 (en) 2001-11-25

Family

ID=27512801

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13924199A IL139241A0 (en) 1998-05-13 1999-05-11 Meiosis regulating compounds

Country Status (3)

Country Link
US (4) US6407086B2 (xx)
KR (1) KR20010043558A (xx)
IL (1) IL139241A0 (xx)

Families Citing this family (37)

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US20040214807A1 (en) * 1993-08-06 2004-10-28 D'amato Robert J. Estrogenic compounds as anti-mitotic agents
US20030004148A1 (en) * 1994-06-23 2003-01-02 Byskov Anne G. Regulation of meiosis
US6346510B1 (en) 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
IL139241A0 (en) * 1998-05-13 2001-11-25 Novo Nordisk As Meiosis regulating compounds
US7087592B1 (en) * 1999-08-23 2006-08-08 Entre Med, Inc. Compositions comprising purified 2-methoxyestradiol and methods of producing same
US7135581B2 (en) * 2000-08-18 2006-11-14 Entremed, Inc. Antiangiogenic agents
US6995278B2 (en) * 2000-08-18 2006-02-07 Entre Med, Inc. Antiangiogenic agents
US20050192258A1 (en) * 2000-08-18 2005-09-01 Agoston Gregory E. Antiangiogenic agents
EP1563309A2 (en) * 2002-11-14 2005-08-17 Novo Nordisk A/S Use of nuclear hormone receptors to identify meiosis regulating compounds
EP1633367A2 (en) * 2003-05-28 2006-03-15 EntreMed, Inc. Antiangiogenic agents
US20070004689A1 (en) * 2004-03-12 2007-01-04 Agoston Gregory E Antiangiogenic agents
US7498322B2 (en) * 2004-03-12 2009-03-03 Entremed, Inc. Antiangiogenic agents
WO2006047022A1 (en) 2004-10-25 2006-05-04 Virginia Commonwealth University Nuclear sulfated oxysterol, potent regulator of cholesterol homeostasis, for therapy of hypercholesterolemia, hyperlipidemia, and atherosclerosis
US8399441B2 (en) 2004-10-25 2013-03-19 Virginia Commonwealth University Nuclear sulfated oxysterol, potent regulator of lipid homeostasis, for therapy of hypercholesterolemia, hypertriglycerides, fatty liver diseases, and atherosclerosis
AU2005309455A1 (en) * 2004-11-29 2006-06-01 Entremed, Inc. A method of administering anti-angiogenic agents and a method of treating disease using same
WO2006123465A1 (ja) * 2005-05-17 2006-11-23 Morinaga Milk Industry Co., Ltd. 膵臓機能改善のための医薬又は飲食品
US20070185069A1 (en) * 2005-11-14 2007-08-09 Plum Stacy M Anti-angiogenic activity of 2-methoxyestradiol in combination with anti-cancer agents
US20070176403A1 (en) * 2006-02-01 2007-08-02 Dennis Calderone Air adjustable seat
CA2646065C (en) * 2006-03-20 2014-01-14 Entremed, Inc. Disease modifying anti-arthritic activity of 2-methoxyestradiol
US20080234243A1 (en) * 2007-01-31 2008-09-25 Lavallee Theresa M Method of treating amyloidosis mediated diseases
WO2012044817A2 (en) * 2010-10-01 2012-04-05 Indiana University Research And Technology Corporation Process for preparing delta-7,9(11) steroids from ganoderma lucidum and analogs thereof
US9034859B2 (en) 2011-04-06 2015-05-19 Virginia Commonwealth University Sulfated oxysterol and oxysterol sulfation by hydroxysterol sulfotransferase promote lipid homeostasis and liver proliferation
CN113956315B (zh) 2011-09-08 2024-08-09 萨奇治疗股份有限公司 神经活性类固醇、组合物、及其用途
EP3932932A1 (en) 2013-03-13 2022-01-05 Sage Therapeutics, Inc. Neuroactive steriods and methods of use thereof
TW202348234A (zh) 2013-12-24 2023-12-16 維吉尼亞聯邦大學 氧化膽固醇硫酸鹽（ｏｃｓ）之用途
US10259840B2 (en) 2014-06-18 2019-04-16 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
MX2020011449A (es) 2015-07-06 2022-02-28 Sage Therapeutics Inc Oxiesteroles y metodos de uso de los mismos.
CA2991313C (en) 2015-07-06 2023-12-19 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
US10696712B2 (en) 2015-07-06 2020-06-30 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
AU2017240157B2 (en) 2016-04-01 2022-10-20 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
US10752653B2 (en) 2016-05-06 2020-08-25 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
MD3481846T2 (ro) 2016-07-07 2021-11-30 Sage Therapeutics Inc 24-Hidroxisteroli 11-substituiți pentru utilizare în tratamentul stărilor legate de NMDA
HRP20220932T1 (hr) 2016-08-02 2022-10-28 Virginia Commonwealth University Sastavi koji sadrže 5-kolesten-3, 25-diol, 3-sulfat (25hc3s) ili njegovu farmaceutski prihvatljivu sol i barem jedan ciklički oligosaharid
CA3038900A1 (en) 2016-09-30 2018-04-05 Sage Therapeutics, Inc. C7 substituted oxysterols and methods as nmda modulators
NZ752732A (en) 2016-10-18 2024-08-30 Sage Therapeutics Inc Oxysterols and methods of use thereof
AU2017345399B2 (en) 2016-10-18 2022-02-24 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
WO2023148764A1 (en) * 2022-02-01 2023-08-10 Translational Health Science And Technology Institute Novel cholic acid derivatives for the treatment and prevention of autoimmune diseases and uses thereof

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FR2129011A5 (xx) * 1971-03-11 1972-10-27 Roussel Uclaf
GB1360354A (en) 1972-01-20 1974-07-17 Union International Co Ltd Chenodeoxycholic acid
NO146279C (no) * 1973-01-10 1982-09-01 Res Inst Medicine Chem Analogifremgangsmaate ved fremstilling av et terapeutisk virksomt 1alfa-hydroksy-25-hydrogen-vitamin d
US3879431A (en) 1973-10-05 1975-04-22 Gen Mills Chem Inc Purification of sterols by distillation
JPS537427B2 (xx) 1974-01-30 1978-03-17
JPS5573700A (en) 1978-11-30 1980-06-03 Teijin Ltd Preparation of steroidal ketone compound
FR2444048B1 (xx) * 1978-12-15 1981-08-14 Roussel Uclaf
DK162648C (da) 1979-02-15 1992-04-13 Teijin Ltd 3beta,25-dihydroxy-24-oxocholest-5-en-derivater og fremgangsmaade til fremstilling heraf
US4196133A (en) 1979-03-05 1980-04-01 Wisconsin Alumni Research Foundation 24,24-Difluoro-25-hydroxycholecalciferol
US4230626A (en) 1979-07-30 1980-10-28 G. D. Searle & Co. 25-Halocholest-5-ene-3β,22-diols and esters thereof
NO162562C (no) * 1981-04-14 1990-01-17 Erregierre Spa 3-alfa,-7beta-dihydroxy-12-keto-5beta-cholansyre og dennes tris-trimethylsilynderivat.
IT1137459B (it) * 1981-04-14 1986-09-10 Erregierre Spa Prodesso per la preparazione di acido ursodeossicolico ad alta purezza
IT1136624B (it) 1981-05-21 1986-09-03 Erregierre Ind Chim Spa Prodotti di salificazione di acidi colici,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo
US4358406A (en) 1981-07-27 1982-11-09 Wisconsin Alumni Research Foundation 26,26,26,27,27,27-Hexafluoro-1α,25-dihydroxycholecalciferol and process for preparing same
ATE26840T1 (de) 1982-01-14 1987-05-15 Duphar Int Res Verfahren zur herstellung von delta 5,7 steroiden.
FI88723C (fi) 1986-05-28 1993-06-28 Ciba Geigy Ag /2,5-dihydro-2-oxo-5-fenyl-3-furanyl/aminer samt deras anvaendning vid framstaellning av ACE-inhibitorer
DE3874763T2 (de) 1987-01-30 1993-04-01 Du Pont Merck Pharma In 14- und 15-stellung substituierte lanosterole und ihre anwendung als hypocholesterolemische mittel.
WO1989007607A1 (en) 1988-02-19 1989-08-24 Broadbent, James, Meredyth 24r-scymnol, and preparation and use thereof
DE3930696A1 (de) * 1989-09-14 1991-03-28 Hoechst Ag Gallensaeurederivate, verfahren zu ihrer herstellung, verwendung als arzneimittel
WO1994018225A1 (en) 1993-02-11 1994-08-18 The Du Pont Merck Pharmaceutical Company 15-oxasterols as hypocholesterolemics
US5716777A (en) 1994-06-23 1998-02-10 Novo Nordisk A/S Regulation of meiosis using sterols
HUP9800731A3 (en) 1995-03-06 2000-03-28 Novo Nordisk As Stimulation of meiosis
KR19990028366A (ko) 1995-06-23 1999-04-15 켈베르그 라르스 감수분열 조절 화합물
CA2275683A1 (en) 1996-12-20 1998-07-02 Frederik Christian Gronvald Meiosis regulating compounds
IL139241A0 (en) * 1998-05-13 2001-11-25 Novo Nordisk As Meiosis regulating compounds

Also Published As

Publication number Publication date
USRE39678E1 (en) 2007-06-05
US6884796B2 (en) 2005-04-26
US6407086B2 (en) 2002-06-18
US20050101573A1 (en) 2005-05-12
KR20010043558A (ko) 2001-05-25
US20020183283A1 (en) 2002-12-05
US20010003782A1 (en) 2001-06-14

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