IT1136624B - Prodotti di salificazione di acidi colici,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo - Google Patents

Prodotti di salificazione di acidi colici,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo

Info

Publication number
IT1136624B
IT1136624B IT21867/81A IT2186781A IT1136624B IT 1136624 B IT1136624 B IT 1136624B IT 21867/81 A IT21867/81 A IT 21867/81A IT 2186781 A IT2186781 A IT 2186781A IT 1136624 B IT1136624 B IT 1136624B
Authority
IT
Italy
Prior art keywords
products
saltification
preparation
active principle
therapeutic compositions
Prior art date
Application number
IT21867/81A
Other languages
English (en)
Other versions
IT8121867A0 (it
Inventor
Antonio Bonaldi
Egidio Molinari
Vanna Springolo
Original Assignee
Erregierre Ind Chim Spa
Proter Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erregierre Ind Chim Spa, Proter Spa filed Critical Erregierre Ind Chim Spa
Publication of IT8121867A0 publication Critical patent/IT8121867A0/it
Priority to IT21867/81A priority Critical patent/IT1136624B/it
Priority to AT82103701T priority patent/ATE11528T1/de
Priority to DE8282103701T priority patent/DE3262109D1/de
Priority to EP82103701A priority patent/EP0065666B1/en
Priority to US06/374,243 priority patent/US4404199A/en
Priority to IE1056/82A priority patent/IE52917B1/en
Priority to CA000402296A priority patent/CA1194469A/en
Priority to PT74864A priority patent/PT74864B/pt
Priority to DK226882A priority patent/DK159456C/da
Priority to NO821672A priority patent/NO158423C/no
Priority to YU1065/82A priority patent/YU43516B/xx
Priority to ES512391A priority patent/ES8302735A1/es
Priority to JP57085079A priority patent/JPS57203098A/ja
Application granted granted Critical
Publication of IT1136624B publication Critical patent/IT1136624B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
IT21867/81A 1981-05-21 1981-05-21 Prodotti di salificazione di acidi colici,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo IT1136624B (it)

Priority Applications (13)

Application Number Priority Date Filing Date Title
IT21867/81A IT1136624B (it) 1981-05-21 1981-05-21 Prodotti di salificazione di acidi colici,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo
AT82103701T ATE11528T1 (de) 1981-05-21 1982-04-30 Salze der cholsaeuren, verfahren zu ihrer herstellung und therapeutische zusammensetzungen, die sie als aktiven bestandteil enthalten.
DE8282103701T DE3262109D1 (en) 1981-05-21 1982-04-30 Salts of cholic acids, process for their preparation and therapeutic compositions containing them as active principles
EP82103701A EP0065666B1 (en) 1981-05-21 1982-04-30 Salts of cholic acids, process for their preparation and therapeutic compositions containing them as active principles
US06/374,243 US4404199A (en) 1981-05-21 1982-05-03 Salification products of cholic acids with trimethoxy-3,4,5-benzoic ester of 2-phenyl-2-dimenthylaminobutanol, having pharmacotherapeutic action, process for their preparation and therapeutic compositions containing them as active principle
IE1056/82A IE52917B1 (en) 1981-05-21 1982-05-04 Salts of cholic acids, process for their preparation and therapeutic compositions containing them as active principles
CA000402296A CA1194469A (en) 1981-05-21 1982-05-05 Salification products of cholic acids, process for their preparation and therapeutic compositions containing them as active principle
PT74864A PT74864B (fr) 1981-05-21 1982-05-10 Procede pour la production de produits de salification des acides coliques en particulier de l'acide quenodioxicolique et ursodeoxicolique
DK226882A DK159456C (da) 1981-05-21 1982-05-19 Analogifremgangsmaade til fremstilling af salte af cholsyrer, specielt chenodeoxycholsyre eller ursodeoxycholsyre, med 3,4,5-trimethoxybenzoesyreesteren af 2-phenyl-2-dimethylaminobutanol
NO821672A NO158423C (no) 1981-05-21 1982-05-19 Analogifremgangsmaate for fremstilling av salter av cholsyrer og trimebutyn.
YU1065/82A YU43516B (en) 1981-05-21 1982-05-19 Process for obtaining salts of ursodezoxyquinlynic acid and trimetoxy-3,4,5-benzo esther of 2-phenyl-2-dimethylbuthanole
ES512391A ES8302735A1 (es) 1981-05-21 1982-05-20 "procedimiento para la preparacion de nuevos compuestos de salificacion de acidos colicos con trimebutina".
JP57085079A JPS57203098A (en) 1981-05-21 1982-05-21 Salt products of cholic acids, manufacture and therapeutical composition containing same as effective component

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21867/81A IT1136624B (it) 1981-05-21 1981-05-21 Prodotti di salificazione di acidi colici,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo

Publications (2)

Publication Number Publication Date
IT8121867A0 IT8121867A0 (it) 1981-05-21
IT1136624B true IT1136624B (it) 1986-09-03

Family

ID=11187975

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21867/81A IT1136624B (it) 1981-05-21 1981-05-21 Prodotti di salificazione di acidi colici,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo

Country Status (13)

Country Link
US (1) US4404199A (it)
EP (1) EP0065666B1 (it)
JP (1) JPS57203098A (it)
AT (1) ATE11528T1 (it)
CA (1) CA1194469A (it)
DE (1) DE3262109D1 (it)
DK (1) DK159456C (it)
ES (1) ES8302735A1 (it)
IE (1) IE52917B1 (it)
IT (1) IT1136624B (it)
NO (1) NO158423C (it)
PT (1) PT74864B (it)
YU (1) YU43516B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1152801B (it) * 1982-08-17 1987-01-14 Proter Spa Composti steroidei ad attivita' coleretica, processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo
US5753269A (en) * 1995-12-27 1998-05-19 Bayer Corporation Otic microbial combinations
IL139241A0 (en) * 1998-05-13 2001-11-25 Novo Nordisk As Meiosis regulating compounds
US6692738B2 (en) 2000-01-27 2004-02-17 The General Hospital Corporation Delivery of therapeutic biologicals from implantable tissue matrices
US20020119921A1 (en) * 1999-03-31 2002-08-29 Michael Streit Thrombospondin-2 and uses thereof
KR20230134598A (ko) 2014-07-29 2023-09-21 센젠 하이타이드 바이오파마슈티컬 리미티드 베르베린 염, 우르소데옥시콜산 염 및 병용물, 이들의 제조 및 응용 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2369M (fr) * 1962-10-17 1964-03-02 Jouveinal Lab Nouveau médicament contre les troubles du systeme nerveux central.
GB1532413A (en) * 1974-12-23 1978-11-15 Union International Co Ltd Chenodeoxycholic acid
GB1431709A (en) * 1973-12-03 1976-04-14 Prodotti Antibiotici Spa Lysozyme derivatives
FR2358144A1 (fr) * 1976-07-13 1978-02-10 Lipha Nouvelle composition medicamenteuse pour le traitement de la lithiase biliaire
US4186143A (en) * 1977-06-20 1980-01-29 Canada Packers Limited Chenodeoxycholic acid recovery process
JPS5529075A (en) * 1978-08-24 1980-03-01 Suzuki Motor Co Ltd Crank room oil recoverer for 2-cycle engine
US4241047A (en) * 1979-07-18 1980-12-23 Lipha, Lyonnaise Industrielle Pharmaceutique Novel medicinal composition for the treatment of biliary lithiasis

Also Published As

Publication number Publication date
IE821056L (en) 1982-11-21
NO821672L (no) 1982-11-22
ES512391A0 (es) 1983-02-01
JPS57203098A (en) 1982-12-13
DK159456B (da) 1990-10-15
YU43516B (en) 1989-08-31
EP0065666A1 (en) 1982-12-01
EP0065666B1 (en) 1985-01-30
DE3262109D1 (en) 1985-03-14
JPS6312478B2 (it) 1988-03-18
US4404199A (en) 1983-09-13
DK159456C (da) 1991-03-18
NO158423B (no) 1988-05-30
ATE11528T1 (de) 1985-02-15
YU106582A (en) 1984-10-31
PT74864B (fr) 1983-12-07
PT74864A (fr) 1982-06-01
CA1194469A (en) 1985-10-01
IT8121867A0 (it) 1981-05-21
ES8302735A1 (es) 1983-02-01
IE52917B1 (en) 1988-04-13
NO158423C (no) 1988-09-14
DK226882A (da) 1982-11-22

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