IL138767A0 - Anticancer compositions - Google Patents

Anticancer compositions

Info

Publication number
IL138767A0
IL138767A0 IL13876799A IL13876799A IL138767A0 IL 138767 A0 IL138767 A0 IL 138767A0 IL 13876799 A IL13876799 A IL 13876799A IL 13876799 A IL13876799 A IL 13876799A IL 138767 A0 IL138767 A0 IL 138767A0
Authority
IL
Israel
Prior art keywords
anticancer compositions
anticancer
compositions
paclitaxel
formulated
Prior art date
Application number
IL13876799A
Other languages
English (en)
Original Assignee
Rtp Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rtp Pharma Inc filed Critical Rtp Pharma Inc
Publication of IL138767A0 publication Critical patent/IL138767A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL13876799A 1998-04-01 1999-03-30 Anticancer compositions IL138767A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8027298P 1998-04-01 1998-04-01
US8027398P 1998-04-01 1998-04-01
PCT/US1999/007162 WO1999049848A1 (en) 1998-04-01 1999-03-30 Anticancer compositions

Publications (1)

Publication Number Publication Date
IL138767A0 true IL138767A0 (en) 2001-10-31

Family

ID=26763305

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13876799A IL138767A0 (en) 1998-04-01 1999-03-30 Anticancer compositions
IL138767A IL138767A (en) 1998-04-01 2000-09-28 Pre-concentrates of Texain that are emulsifiable and stable in storage

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL138767A IL138767A (en) 1998-04-01 2000-09-28 Pre-concentrates of Texain that are emulsifiable and stable in storage

Country Status (12)

Country Link
EP (1) EP1067908B9 (sv)
JP (1) JP4695260B2 (sv)
KR (1) KR100661879B1 (sv)
CN (1) CN100341485C (sv)
AT (1) ATE327735T1 (sv)
AU (1) AU756752B2 (sv)
CA (1) CA2326485C (sv)
DE (1) DE69931617T2 (sv)
IL (2) IL138767A0 (sv)
SE (1) SE0003449L (sv)
TW (1) TW546152B (sv)
WO (1) WO1999049848A1 (sv)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6964946B1 (en) * 1995-10-26 2005-11-15 Baker Norton Pharmaceuticals, Inc. Oral pharmaceutical compositions containing taxanes and methods of treatment employing the same
IL132992A0 (en) * 1997-05-27 2001-03-19 Baker Norton Pharma Method and compositions for administering taxanes orally to human patients
EP1479382A1 (en) * 1999-06-18 2004-11-24 IVAX Research, Inc. Oral pharmaceutical compositions containing taxanes and methods for treatment employing the same
AU7984200A (en) * 1999-09-21 2001-04-24 Skyepharma Canada Inc. Surface modified particulate compositions of biologically active substances
AU2006201100B2 (en) * 1999-09-21 2009-09-24 Jagotec Ag Surface modified particulate compositions of biologically active substances
AU7638300A (en) * 1999-10-20 2001-04-30 Vesifact Ag Microemulsion preconcentrates and microemulsions
CZ20021484A3 (cs) * 1999-10-27 2003-12-17 Baker Norton Pharmaceuticals, Inc. Farmaceutický prostředek obsahující taxan pro orální podávání lidem
EP1118333A1 (en) * 2000-01-18 2001-07-25 Eurand International S.P.A. Compositions with enhanced oral bioavailability
DE10030378A1 (de) * 2000-06-21 2002-03-14 Audit Inst For Medical Service Neue pharmazeutische Zusammensetzung zur topischen Anwendung von wasserunlöslichen und/oder schwer wasserlöslichen Wirkstoffen
ES2238050T3 (es) * 2000-07-24 2005-08-16 PHARMACIA & UPJOHN COMPANY LLC Sistemas emulsionantes de liberacion de farmacos para farmacos lipofilos extremadamente insolubles en agua.
US6919370B2 (en) 2000-11-28 2005-07-19 Transform Pharmaceuticals, Inc. Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof
US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
PT1249231E (pt) * 2001-04-12 2004-06-30 Vesifact Ag Formulacoes farmaceuticas contendo substancias activas anti-inflamatorias e sua utilizacao
KR100774366B1 (ko) 2001-09-10 2007-11-08 주식회사 중외제약 파클리탁셀 주사제 조성물
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
WO2003045357A1 (en) * 2001-11-27 2003-06-05 Transform Pharmaceuticals, Inc. Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof
CA2468845C (en) * 2001-12-03 2011-08-23 Dor Biopharma Inc. Stabilized reverse micelle compositions and uses thereof
WO2003097027A1 (fr) * 2002-05-22 2003-11-27 Nihon Pharmaceutical Co., Ltd. Emulsion huile dans eau de 1-menthol
KR20040008816A (ko) * 2002-07-19 2004-01-31 한미약품 주식회사 파클리탁셀 또는 그의 유도체와 p-당단백질 저해제를함유하는 혈관재협착 방지를 위한 경구투여용 약학 조성물
KR100573289B1 (ko) * 2002-07-20 2006-04-24 대화제약 주식회사 방광내 투여를 통한 방광암치료용 파클리탁셀 조성물 및그의 제조 방법
DE10247399A1 (de) * 2002-10-08 2004-04-29 Schering Ag Pharmazeutische Zubereitungen, Verwendung dieser Zubereitung und Verfahren zur Erhöhung der Bioverfügbarkeit von peroral zu applizierenden Arzneistoffen
EP1498120A1 (en) 2003-07-18 2005-01-19 Aventis Pharma S.A. Semi-solid formulations for the oral administration of taxoids
EP1498143A1 (en) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Self-emulsifying and self-microemulsifying formulations for the oral administration of taxoids
WO2005037250A1 (en) * 2003-10-17 2005-04-28 Amylin Pharmaceuticals, Inc. Self emulsifying drug delivery systems for hydrophobic therapeutic compounds
WO2005037251A1 (en) * 2003-10-17 2005-04-28 Amylin Pharmaceuticals, Inc. Self-emulsifying drug delivery systems for hydrophobic therapeutic compounds
WO2005079758A1 (en) 2004-02-13 2005-09-01 Bioavailability, Inc. A microemulsion preparation of high concentration propofol for anesthetic uses
JPWO2005089716A1 (ja) * 2004-03-24 2008-01-31 武田薬品工業株式会社 高含量化製剤
US7345093B2 (en) 2004-04-27 2008-03-18 Formatech, Inc. Methods of enhancing solubility of compounds
US7659310B2 (en) 2004-04-27 2010-02-09 Formatech, Inc. Methods of enhancing solubility of agents
FR2873585B1 (fr) * 2004-07-27 2006-11-17 Aventis Pharma Sa Nouvelles formulations galeniques de principes actifs
CN100361656C (zh) 2004-08-27 2008-01-16 石药集团中奇制药技术(石家庄)有限公司 丁苯酞自乳化释药体系及其制备方法和应用
HUE029192T2 (en) 2005-03-21 2017-02-28 Teva Czech Ind S R O Anti-crystallization and its use in gelatin capsules
WO2008058366A1 (en) * 2006-09-28 2008-05-22 Université de Montréal Oil-in-water emulsions, methods of use thereof, methods of preparation thereof and kits thereof
US20090088393A1 (en) * 2007-09-28 2009-04-02 Zomanex, Llc Methods and formulations for converting intravenous and injectable drugs into oral dosage forms
EP2204167A1 (en) * 2009-01-05 2010-07-07 Azad Pharma AG Pharmaceutical microemulsion for preventing supramolecular aggregation of amphiphilic molecules
CN101785757B (zh) * 2009-01-22 2012-02-22 美迪思生物科技(北京)有限公司 一种紫杉醇自乳化制剂及其制备方法和用途
EP2301523A1 (de) * 2009-09-22 2011-03-30 Dr. August Wolff GmbH & Co. KG Arzneimittel Galenische Formulierung in kolloidaler Form
US10143652B2 (en) 2009-09-23 2018-12-04 Curirx Inc. Methods for the preparation of liposomes
US9402812B2 (en) 2009-09-23 2016-08-02 Indu JAVERI Methods for the preparation of liposomes
CN102228431A (zh) * 2010-03-16 2011-11-02 王国强 紫杉烷类化合物的自乳化药物组合物
SG10201503234SA (en) * 2010-05-03 2015-06-29 Teikoku Pharma Usa Inc Non-Aqueous Taxane Pro-Emulsion Formulations and Methods of Making and Using the Same
US20120095098A1 (en) * 2010-10-18 2012-04-19 Bhiku Patel Bioavailability Enhancement Delivery System
JO3685B1 (ar) * 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
EP2878311A1 (en) * 2013-11-27 2015-06-03 Freund Pharmatec Ltd. Solubility Enhancement for Hydrophobic Drugs
JP2017500355A (ja) * 2013-12-23 2017-01-05 ジョンソン・アンド・ジョンソン・コンシューマー・インコーポレイテッド ラセカドトリル組成物
DE102014015625A1 (de) 2014-10-16 2016-04-21 Gonzalo Urrutia Desmaison Lösungsvermittelnde Zusammenssetzungen
KR101542364B1 (ko) * 2014-10-31 2015-08-07 대화제약 주식회사 탁산을 포함하는 경구 투여용 약학 조성물
US10987335B2 (en) * 2015-07-30 2021-04-27 Dae Hwa Pharma. Co., Ltd. Pharmaceutical composition for oral administration comprising high concentration taxane
TWI752750B (zh) 2015-09-30 2022-01-11 香港商慧源香港創新有限公司 口服紫杉烷組合物及方法
CN109589305B (zh) * 2018-12-03 2021-03-19 昆明积大制药股份有限公司 多西他赛-环孢素a共包载自乳化制剂及其制备方法
JP7219344B2 (ja) * 2019-01-07 2023-02-07 プサン ナショナル ユニバーシティ インダストリー-ユニバーシティ コーポレーション ファウンデーション 血液脳関門の透過性を増進させるw/o/w型トリオレインエマルジョンを利用した薬物伝達プラットホーム

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE234088T1 (de) * 1992-09-22 2003-03-15 Us Gov Health & Human Serv Taxol zur behandlung von lymphomen und brustkrebs und zur verminderung der multi-drug resistenz gegen taxol
US5567592A (en) * 1994-02-02 1996-10-22 Regents Of The University Of California Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal
US5616330A (en) * 1994-07-19 1997-04-01 Hemagen/Pfc Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same
US5560931A (en) * 1995-02-14 1996-10-01 Nawosystems L.L.C. Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids
GB9509321D0 (en) * 1995-05-09 1995-06-28 Zylepsis Ltd Methods of and substances for inhibiting oxidative enzymes
TW527186B (en) * 1996-03-19 2003-04-11 Janssen Pharmaceutica Nv Fused imidazole derivatives as multidrug resistance modulators
US5919815A (en) * 1996-05-22 1999-07-06 Neuromedica, Inc. Taxane compounds and compositions
US6060518A (en) * 1996-08-16 2000-05-09 Supratek Pharma Inc. Polymer compositions for chemotherapy and methods of treatment using the same
JP2001524963A (ja) * 1997-03-27 2001-12-04 ベーカー ノートン ファーマシューティカルズ インコーポレイテッド 卵巣癌を治療するための方法及び組成物

Also Published As

Publication number Publication date
IL138767A (en) 2007-06-03
SE0003449D0 (sv) 2000-09-27
CN1303269A (zh) 2001-07-11
CA2326485A1 (en) 1999-10-07
DE69931617D1 (de) 2006-07-06
CN100341485C (zh) 2007-10-10
KR100661879B1 (ko) 2006-12-27
JP4695260B2 (ja) 2011-06-08
EP1067908A1 (en) 2001-01-17
TW546152B (en) 2003-08-11
AU3377099A (en) 1999-10-18
AU756752B2 (en) 2003-01-23
JP2002509877A (ja) 2002-04-02
EP1067908B1 (en) 2006-05-31
CA2326485C (en) 2008-12-09
EP1067908B9 (en) 2007-01-24
ATE327735T1 (de) 2006-06-15
WO1999049848A1 (en) 1999-10-07
DE69931617T2 (de) 2007-05-24
KR20010034622A (ko) 2001-04-25
SE0003449L (sv) 2000-11-23

Similar Documents

Publication Publication Date Title
IL138767A0 (en) Anticancer compositions
HK1080364A1 (en) Oral pharmaceutical forms of liquid drugs having improved bioavailability
IL128801A (en) Pharmaceutical composition comprising a substance inhibiting no synthase
WO2004054542A3 (en) Oral drug delivery system comprising high viscosity liquid carrier materials
ATE293995T1 (de) Pharmazeutische zusammensetzungen, die wirkstoffabsorptionsfördernde verbindungen enthalten
ATE509616T1 (de) Topische pharmazeutische und/oder cosmetische dosierungssysteme
HK1096034A1 (en) A solid dosage form comprising a fibrate
MXPA03007712A (es) Sales farmaceuticas.
WO2006035417A3 (en) Dihydropyrimidine microcapsule - formulations
AU2845599A (en) Pharmaceutical compositions and their use
ATE460921T1 (de) Medikamenthaltige zusammensetzung in aerosolform
WO2001041737A3 (en) Solid oral dosage form
BR0014383A (pt) Composições de liberação controlada compreendendo nimesulida
ATE224717T1 (de) Oral anzuwendende arzneizubereitungen enthaltend eine benzhydrylpiperazine und eine zyklodextrin
WO2002008217A3 (en) COUMARIN DERIVATIVES USEFUL AS TNFα INHIBITORS
HUP0400832A3 (en) New amidoalkyl-piperidine and amidoalkyl-piperazine derivatives, and pharmaceutical compositions containing such derivatives as active ingredients
ATE202931T1 (de) Taxanderivate enthaltende arzneizubereitungen
AU2084801A (en) Antiviral medication
CA2352915A1 (en) Pharmaceutical compositions containing mupirocin
MXPA03002807A (es) Estabilizacion de formulaciones solidas de farmacos.
DE60202590D1 (de) 2h-1-benzopyran-derivate, prozesse zu ihrer herstellung und pharmazeutische zusammensetzungen
AU1650501A (en) 1,3,4-oxadiazoline derivatives and drugs containing these derivatives as the active ingredient
MY133230A (en) Combination of no synthase inhibitor(s) and metabolic antioxidant(s)
WO2002000191A3 (de) Bdellosomen
CA2185883A1 (en) The use of dimeticone as a transport and carrier system and/or drug delivery system

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed