IL138345A - Composition comprising eprosartan and its use in the preparation of medicaments for blocking angiotensin ii receptors and for treating hypertension, congestive heart failure and renal failure - Google Patents
Composition comprising eprosartan and its use in the preparation of medicaments for blocking angiotensin ii receptors and for treating hypertension, congestive heart failure and renal failureInfo
- Publication number
- IL138345A IL138345A IL13834599A IL13834599A IL138345A IL 138345 A IL138345 A IL 138345A IL 13834599 A IL13834599 A IL 13834599A IL 13834599 A IL13834599 A IL 13834599A IL 138345 A IL138345 A IL 138345A
- Authority
- IL
- Israel
- Prior art keywords
- eprosartan
- composition
- preparation
- salt
- medicament
- Prior art date
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7766098P | 1998-03-11 | 1998-03-11 | |
| PCT/US1999/004651 WO1999045779A1 (en) | 1998-03-11 | 1999-03-11 | Novel compositions of eprosartan |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL138345A0 IL138345A0 (en) | 2001-10-31 |
| IL138345A true IL138345A (en) | 2004-12-15 |
Family
ID=22139347
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13834599A IL138345A (en) | 1998-03-11 | 1999-03-11 | Composition comprising eprosartan and its use in the preparation of medicaments for blocking angiotensin ii receptors and for treating hypertension, congestive heart failure and renal failure |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1061803B1 (cs) |
| JP (1) | JP2002506010A (cs) |
| KR (1) | KR20010041796A (cs) |
| CN (1) | CN1299235A (cs) |
| AT (1) | ATE508633T1 (cs) |
| AU (1) | AU757547B2 (cs) |
| BR (1) | BR9908691A (cs) |
| CA (1) | CA2323363C (cs) |
| CY (1) | CY1111738T1 (cs) |
| CZ (1) | CZ303067B6 (cs) |
| DK (1) | DK1061803T3 (cs) |
| ES (1) | ES2366394T3 (cs) |
| HU (1) | HU228574B1 (cs) |
| IL (1) | IL138345A (cs) |
| NO (1) | NO331207B1 (cs) |
| NZ (1) | NZ506700A (cs) |
| PL (1) | PL192545B1 (cs) |
| SI (1) | SI1061803T1 (cs) |
| TR (1) | TR200002646T2 (cs) |
| WO (1) | WO1999045779A1 (cs) |
| ZA (1) | ZA991922B (cs) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0810853B1 (en) | 1995-02-24 | 2004-08-25 | Elan Pharma International Limited | Aerosols containing nanoparticle dispersions |
| CN1198591C (zh) * | 1998-07-20 | 2005-04-27 | 史密丝克莱恩比彻姆公司 | 在口服固体剂型中包含依普沙坦的生物利用度提高的制剂 |
| US7521068B2 (en) | 1998-11-12 | 2009-04-21 | Elan Pharma International Ltd. | Dry powder aerosols of nanoparticulate drugs |
| CN1422152A (zh) * | 2000-04-12 | 2003-06-04 | 诺瓦提斯公司 | 有机化合物的联合形式 |
| DE10230272A1 (de) * | 2002-07-05 | 2004-01-22 | Solvay Pharmaceuticals Gmbh | AT1-Rezeptorantagonisten zur Prävention von Folgeschlaganfällen |
| EP1382334A1 (en) * | 2002-07-11 | 2004-01-21 | Université de Picardie Jules Verne | Use of angiotensin II AT1-receptor blockers (ARB), alone or combined with thiazide or angiotensin II for the treatment of stroke |
| US7232828B2 (en) * | 2002-08-10 | 2007-06-19 | Bethesda Pharmaceuticals, Inc. | PPAR Ligands that do not cause fluid retention, edema or congestive heart failure |
| AU2004206109A1 (en) * | 2003-01-21 | 2004-08-05 | Ranbaxy Laboratories Limited | Co-precipitated amorphous losartan and dosage forms comprising the same |
| BRPI0406987A (pt) | 2003-01-31 | 2006-01-10 | Sankyo Co | Medicamento para a prevenção e/ou tratamento de arteriosclerose, medicamentos para a inibição de proliferação de células do músculo liso vascular, de formação de neoìntima dos vasos sanguìneos e de remodelação vascular, medicamento para a prevenção de restenose que segue intervenção coronária percutânea, e, medicamentos para a profilaxia e/ou tratamento de hipertensão ou doenças causadas por hipertensão ou doenças causadas por hipertensão, de doenças cardìacas, de angina do peito, de infarto miocárdico, de arritmia, de morte súbita, de insuficiência cardìaca, de hipertrofia cardìaca, de doenças renais, de nefropatia diabética, de glomerulonefrite, de nefrosclerose, de doenças cerebrovasculares, de infarto cerebral, e de hemorragia cerebral |
| AU2005256634B2 (en) * | 2004-06-23 | 2010-12-09 | Solvay Pharmaceuticals Gmbh | Pharmaceutical compositions comprising NEP-inhibitors, inhibitors of the endogenous endothelin producing system and AT1-receptor antagonists |
| US20060099230A1 (en) * | 2004-11-10 | 2006-05-11 | Chin-Chih Chiang | Novel formulations of eprosartan with enhanced bioavailability |
| WO2006136916A2 (en) * | 2005-06-20 | 2006-12-28 | Glenmark Pharmaceuticals Limited | Substantially pure micronized particles of telmisartan and pharmaceutical compositions containing same |
| KR100715355B1 (ko) * | 2005-09-30 | 2007-05-07 | 주식회사유한양행 | 프란루카스트를 함유하는 분무-건조 과립 및 그의 제조방법 |
| WO2009013760A2 (en) * | 2007-07-25 | 2009-01-29 | Hetero Drugs Limited | Eprosartan mesylate crystalline particles and a process for preparing pure eprosartan |
| EP2108365A1 (en) * | 2008-04-09 | 2009-10-14 | LEK Pharmaceuticals d.d. | Single dosage pharmaceutical formulation comprising eprosartan mesylate |
| CN103705510A (zh) * | 2013-12-27 | 2014-04-09 | 华润赛科药业有限责任公司 | 一种阿齐沙坦固体组合物的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4107288A (en) * | 1974-09-18 | 1978-08-15 | Pharmaceutical Society Of Victoria | Injectable compositions, nanoparticles useful therein, and process of manufacturing same |
| DE3013839A1 (de) * | 1979-04-13 | 1980-10-30 | Freunt Ind Co Ltd | Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung |
| JPS587609B2 (ja) | 1979-06-17 | 1983-02-10 | フロイント産業株式会社 | 粉体薬剤のコ−テング法 |
| US5185351A (en) * | 1989-06-14 | 1993-02-09 | Smithkline Beecham Corporation | Imidazolyl-alkenoic acids useful as angiotensin II receptor antagonists |
| JP2642486B2 (ja) | 1989-08-04 | 1997-08-20 | 田辺製薬株式会社 | 難溶性薬物の超微粒子化法 |
| US5145684A (en) * | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
| EA001958B1 (ru) | 1996-03-29 | 2001-10-22 | Смитклайн Бичам Корпорейшн | Дигидрат эпросартана и способ его получения и готовая препаративная форма |
| NZ502644A (en) * | 1997-08-06 | 2002-03-01 | Smithkline Beecham Corp | Eprosartan arginyl charge-neutralization-complex useful for treating diseases where blockade of the angiotensin II receptor is indicated |
-
1999
- 1999-03-10 ZA ZA9901922A patent/ZA991922B/xx unknown
- 1999-03-11 HU HU0101243A patent/HU228574B1/hu not_active IP Right Cessation
- 1999-03-11 ES ES99909780T patent/ES2366394T3/es not_active Expired - Lifetime
- 1999-03-11 WO PCT/US1999/004651 patent/WO1999045779A1/en not_active Ceased
- 1999-03-11 TR TR2000/02646T patent/TR200002646T2/xx unknown
- 1999-03-11 SI SI9931058T patent/SI1061803T1/sl unknown
- 1999-03-11 AU AU28909/99A patent/AU757547B2/en not_active Ceased
- 1999-03-11 KR KR1020007010070A patent/KR20010041796A/ko not_active Ceased
- 1999-03-11 EP EP99909780A patent/EP1061803B1/en not_active Expired - Lifetime
- 1999-03-11 CN CN99805844A patent/CN1299235A/zh active Pending
- 1999-03-11 AT AT99909780T patent/ATE508633T1/de active
- 1999-03-11 CZ CZ20003288A patent/CZ303067B6/cs not_active IP Right Cessation
- 1999-03-11 CA CA002323363A patent/CA2323363C/en not_active Expired - Fee Related
- 1999-03-11 DK DK99909780.1T patent/DK1061803T3/da active
- 1999-03-11 NZ NZ506700A patent/NZ506700A/xx not_active IP Right Cessation
- 1999-03-11 BR BR9908691-3A patent/BR9908691A/pt not_active Application Discontinuation
- 1999-03-11 JP JP2000535205A patent/JP2002506010A/ja not_active Ceased
- 1999-03-11 PL PL343411A patent/PL192545B1/pl not_active IP Right Cessation
- 1999-03-11 IL IL13834599A patent/IL138345A/en not_active IP Right Cessation
-
2000
- 2000-09-08 NO NO20004502A patent/NO331207B1/no not_active IP Right Cessation
-
2011
- 2011-07-25 CY CY20111100730T patent/CY1111738T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU757547B2 (en) | 2003-02-27 |
| EP1061803B1 (en) | 2011-05-11 |
| NO20004502D0 (no) | 2000-09-08 |
| SI1061803T1 (sl) | 2011-09-30 |
| KR20010041796A (ko) | 2001-05-25 |
| CY1111738T1 (el) | 2015-10-07 |
| WO1999045779A1 (en) | 1999-09-16 |
| EP1061803A1 (en) | 2000-12-27 |
| AU2890999A (en) | 1999-09-27 |
| ATE508633T1 (de) | 2011-05-15 |
| IL138345A0 (en) | 2001-10-31 |
| PL343411A1 (en) | 2001-08-13 |
| NZ506700A (en) | 2003-03-28 |
| NO20004502L (no) | 2000-11-07 |
| CN1299235A (zh) | 2001-06-13 |
| HUP0101243A1 (hu) | 2002-05-29 |
| ES2366394T3 (es) | 2011-10-19 |
| EP1061803A4 (en) | 2007-12-26 |
| ZA991922B (en) | 1999-09-13 |
| CA2323363A1 (en) | 1999-09-16 |
| HU228574B1 (en) | 2013-04-29 |
| JP2002506010A (ja) | 2002-02-26 |
| CA2323363C (en) | 2008-09-30 |
| NO331207B1 (no) | 2011-10-31 |
| CZ303067B6 (cs) | 2012-03-21 |
| TR200002646T2 (tr) | 2001-01-22 |
| HUP0101243A3 (en) | 2005-09-28 |
| BR9908691A (pt) | 2000-12-26 |
| CZ20003288A3 (cs) | 2001-03-14 |
| PL192545B1 (pl) | 2006-11-30 |
| DK1061803T3 (da) | 2011-08-29 |
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Legal Events
| Date | Code | Title | Description |
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| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |