IL138034A0 - Apo-2 ligand-anti-her-2 antibody synergism - Google Patents

Apo-2 ligand-anti-her-2 antibody synergism

Info

Publication number
IL138034A0
IL138034A0 IL13803499A IL13803499A IL138034A0 IL 138034 A0 IL138034 A0 IL 138034A0 IL 13803499 A IL13803499 A IL 13803499A IL 13803499 A IL13803499 A IL 13803499A IL 138034 A0 IL138034 A0 IL 138034A0
Authority
IL
Israel
Prior art keywords
apo
ligand
synergism
antibody
antibody synergism
Prior art date
Application number
IL13803499A
Other languages
English (en)
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of IL138034A0 publication Critical patent/IL138034A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL13803499A 1998-03-27 1999-03-26 Apo-2 ligand-anti-her-2 antibody synergism IL138034A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7968398P 1998-03-27 1998-03-27
PCT/US1999/006673 WO1999048527A1 (en) 1998-03-27 1999-03-26 Apo-2 ligand-anti-her-2 antibody synergism

Publications (1)

Publication Number Publication Date
IL138034A0 true IL138034A0 (en) 2001-10-31

Family

ID=22152138

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13803499A IL138034A0 (en) 1998-03-27 1999-03-26 Apo-2 ligand-anti-her-2 antibody synergism
IL138034A IL138034A (en) 1998-03-27 2000-08-23 Apo-2 ligand-anti-her-2 antibody synergism

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL138034A IL138034A (en) 1998-03-27 2000-08-23 Apo-2 ligand-anti-her-2 antibody synergism

Country Status (14)

Country Link
US (5) US20020141993A1 (da)
EP (1) EP1064027B1 (da)
JP (2) JP2002507404A (da)
AT (1) ATE398464T1 (da)
AU (3) AU765003B2 (da)
CA (1) CA2324494A1 (da)
CY (1) CY1108320T1 (da)
DE (1) DE69938923D1 (da)
DK (1) DK1064027T3 (da)
ES (1) ES2308836T3 (da)
HK (1) HK1034040A1 (da)
IL (2) IL138034A0 (da)
PT (1) PT1064027E (da)
WO (1) WO1999048527A1 (da)

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US6949245B1 (en) * 1999-06-25 2005-09-27 Genentech, Inc. Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
US20040013667A1 (en) * 1999-06-25 2004-01-22 Genentech, Inc. Treatment with anti-ErbB2 antibodies
TR200200472T2 (tr) 1999-08-27 2002-06-21 Genentech, Inc. Anti-Erb B2 antikorları ile tedavi için dozajlar
JP2003523207A (ja) 2000-01-25 2003-08-05 ジェネンテック・インコーポレーテッド Ｌｉｖ−１関連タンパク質、それをコードするポリヌクレオチド、及び癌の治療へのその利用
AU2001259271A1 (en) * 2000-04-28 2001-11-12 Millennium Pharmaceuticals, Inc. 14094, a novel human trypsin family member and uses thereof
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DE10034607A1 (de) * 2000-07-20 2002-02-07 Gundram Jung Multispezifisches Reagenz zur selektiven Stimulierung von Zelloberflächenrezeptoren
DE60136816D1 (de) * 2000-07-27 2009-01-15 Genentech Inc Sequentielle verabreichung von cpt-11 und apo-2l polypeptid
US20060062786A1 (en) * 2000-11-08 2006-03-23 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to TRAIL receptors
US20030228309A1 (en) * 2000-11-08 2003-12-11 Theodora Salcedo Antibodies that immunospecifically bind to TRAIL receptors
US7361341B2 (en) * 2001-05-25 2008-04-22 Human Genome Sciences, Inc. Methods of treating cancer using antibodies that immunospecifically bind to trail receptors
US7348003B2 (en) 2001-05-25 2008-03-25 Human Genome Sciences, Inc. Methods of treating cancer using antibodies that immunospecifically bind to TRAIL receptors
US20050214209A1 (en) * 2001-05-25 2005-09-29 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to TRAIL receptors
US20050129616A1 (en) * 2001-05-25 2005-06-16 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to TRAIL receptors
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CN1997382A (zh) * 2004-05-05 2007-07-11 梅里麦克制药股份有限公司 调节生物活性的双特异性结合剂
GT200500155A (es) * 2004-06-16 2006-05-15 Terapia del càncer resistente al platino
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WO2006063042A2 (en) * 2004-12-07 2006-06-15 Genentech, Inc. Selecting patients for therapy with a her inhibitor
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US8557588B2 (en) * 2007-03-27 2013-10-15 Schlumberger Technology Corporation Methods and apparatus for sampling and diluting concentrated emulsions
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Also Published As

Publication number Publication date
AU2010201871A1 (en) 2010-05-27
US20080160026A1 (en) 2008-07-03
AU765003B2 (en) 2003-09-04
US20070026001A1 (en) 2007-02-01
IL138034A (en) 2007-12-03
PT1064027E (pt) 2008-09-29
ATE398464T1 (de) 2008-07-15
EP1064027B1 (en) 2008-06-18
DE69938923D1 (de) 2008-07-31
CA2324494A1 (en) 1999-09-30
US20080241146A1 (en) 2008-10-02
WO1999048527A1 (en) 1999-09-30
CY1108320T1 (el) 2014-02-12
US20050244417A1 (en) 2005-11-03
AU2003266765A1 (en) 2004-01-15
ES2308836T3 (es) 2008-12-01
JP2002507404A (ja) 2002-03-12
AU3365999A (en) 1999-10-18
US20020141993A1 (en) 2002-10-03
HK1034040A1 (en) 2001-10-12
DK1064027T3 (da) 2008-09-08
EP1064027A1 (en) 2001-01-03
JP2010088438A (ja) 2010-04-22

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