IL137466A0 - Breast cancer resistance protein (bcrp) and the dna which encodes it - Google Patents

Breast cancer resistance protein (bcrp) and the dna which encodes it

Info

Publication number
IL137466A0
IL137466A0 IL13746699A IL13746699A IL137466A0 IL 137466 A0 IL137466 A0 IL 137466A0 IL 13746699 A IL13746699 A IL 13746699A IL 13746699 A IL13746699 A IL 13746699A IL 137466 A0 IL137466 A0 IL 137466A0
Authority
IL
Israel
Prior art keywords
breast cancer
bcrp
encodes
dna
resistance protein
Prior art date
Application number
IL13746699A
Other languages
English (en)
Original Assignee
Univ Maryland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22115664&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL137466(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Maryland filed Critical Univ Maryland
Publication of IL137466A0 publication Critical patent/IL137466A0/xx

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57415Specifically defined cancers of breast
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/44Multiple drug resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL13746699A 1998-02-05 1999-02-05 Breast cancer resistance protein (bcrp) and the dna which encodes it IL137466A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7376398P 1998-02-05 1998-02-05
PCT/US1999/002577 WO1999040110A1 (en) 1998-02-05 1999-02-05 Breast cancer resistance protein (bcrp) and the dna which encodes it

Publications (1)

Publication Number Publication Date
IL137466A0 true IL137466A0 (en) 2001-07-24

Family

ID=22115664

Family Applications (4)

Application Number Title Priority Date Filing Date
IL13746699A IL137466A0 (en) 1998-02-05 1999-02-05 Breast cancer resistance protein (bcrp) and the dna which encodes it
IL137466A IL137466A (en) 1998-02-05 2000-07-24 Polynucleotides of breast cancer resistance proteins (bcrp), nucleic acids, plasmids and expression vectors encoding the same
IL177612A IL177612A (en) 1998-02-05 2006-08-21 Breast cancer resistance protein (bcrp) and methods for identifying inhibitors thereof
IL191982A IL191982A (en) 1998-02-05 2008-06-05 Antibody binding to breast cancer resistance protein (bcrp) and screening methods using the same

Family Applications After (3)

Application Number Title Priority Date Filing Date
IL137466A IL137466A (en) 1998-02-05 2000-07-24 Polynucleotides of breast cancer resistance proteins (bcrp), nucleic acids, plasmids and expression vectors encoding the same
IL177612A IL177612A (en) 1998-02-05 2006-08-21 Breast cancer resistance protein (bcrp) and methods for identifying inhibitors thereof
IL191982A IL191982A (en) 1998-02-05 2008-06-05 Antibody binding to breast cancer resistance protein (bcrp) and screening methods using the same

Country Status (10)

Country Link
US (4) US6313277B1 (de)
EP (1) EP1054894B2 (de)
JP (1) JP4187412B2 (de)
AT (1) ATE359291T1 (de)
AU (1) AU755567B2 (de)
CA (1) CA2319715C (de)
DE (1) DE69935782T3 (de)
ES (1) ES2284243T5 (de)
IL (4) IL137466A0 (de)
WO (1) WO1999040110A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2284243T5 (es) * 1998-02-05 2017-08-22 University Of Maryland Baltimore Proteína de resistencia de cáncer de mama (BCRP) y el ADN que la codifica
US7622557B2 (en) * 1998-05-28 2009-11-24 St. Jude Children's Research Hospital Antibodies having binding specificity for the extracellular domain of a breast cancer resistance protein (BCRP)
WO1999061589A2 (en) 1998-05-28 1999-12-02 St. Jude Children's Research Hospital Expansion of hematopoietic stem cells transduced with mdr-1 and methods of use thereof
US7138493B1 (en) * 1998-11-30 2006-11-21 The United States Of America As Represented By The Department Of Health And Human Services ATP-binding cassette protein responsible for cytotoxin resistance
AU1924000A (en) * 1998-11-30 2000-07-03 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The An atp-binding cassette protein responsible for cytotoxin resistance
WO2000069390A2 (en) * 1999-05-17 2000-11-23 Cancer Research Ventures Limited Compositions for improving bioavailability of orally administered drugs
AU2001288061A1 (en) * 2000-10-03 2002-04-15 Banyu Pharmaceutical Co., Ltd. Drug resistance-associated gene and use thereof
HU0100947D0 (en) * 2001-03-02 2001-05-28 Solvo Kft Screening system based on expression of abcg2 half transporter protein in an expression system free of other abc-transporters, abcg2 homodimers
WO2003035685A1 (en) * 2001-10-24 2003-05-01 Solvo Biotechnology Inc. Use of a half-transporter protein of the abcg-family for selecting cells and in gene therapy
US20060135445A1 (en) * 2003-02-04 2006-06-22 Kabushiki Kaisha Yakult Honsha Breast cancer-resistant protein inhibitor
JP2006069910A (ja) * 2004-08-31 2006-03-16 Yoshiichi Sugimoto 抗癌剤耐性克服剤
EP1672365A1 (de) * 2004-12-16 2006-06-21 Het Nederlands Kanker Instituut Mittel und Verfahren zur Bestimmung und Beeinflussung des zellulären Transports
US7465788B2 (en) * 2005-01-18 2008-12-16 University Of Maryland Breast cancer resistance protein (BCRP) and antibodies thereto
CN108949694B (zh) 2012-09-11 2022-06-17 康宁有限公司 瞬时过表达编码药物转运蛋白和/或药物代谢酶的基因的可消耗的低温保存的细胞
KR101561965B1 (ko) 2013-11-27 2015-10-20 한국과학기술연구원 디스코이딘 도메인 수용체 2 활성을 조절하는 물질의 동정 방법
EP3966340A4 (de) * 2019-05-08 2024-01-03 The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization Aro Vo Terpen-synthasen und transporter

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5585479A (en) * 1992-07-24 1996-12-17 The United States Of America As Represented By The Secretary Of The Navy Antisense oligonucleotides directed against human ELAM-I RNA
US5489519A (en) * 1992-10-27 1996-02-06 Queen's University At Kingston Multidrug resistance protein
EP0975795A1 (de) * 1997-02-24 2000-02-02 TM Technologies Inc. Verfahren zur selektion von anti-strang-oligonukleotiden
WO1998055614A2 (en) * 1997-06-04 1998-12-10 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
ES2284243T5 (es) * 1998-02-05 2017-08-22 University Of Maryland Baltimore Proteína de resistencia de cáncer de mama (BCRP) y el ADN que la codifica
JP2002534055A (ja) * 1998-05-14 2002-10-15 カイロン コーポレイション ヒト遺伝子および遺伝子発現産物v
CA2344107A1 (en) * 1998-09-25 2000-04-06 Bayer Aktiengesellschaft Atp binding cassette genes and proteins for diagnosis and treatment of lipid disorders and inflammatory diseases
AU1924000A (en) * 1998-11-30 2000-07-03 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The An atp-binding cassette protein responsible for cytotoxin resistance
AU2001288061A1 (en) 2000-10-03 2002-04-15 Banyu Pharmaceutical Co., Ltd. Drug resistance-associated gene and use thereof
JP2005529618A (ja) 2002-06-17 2005-10-06 萬有製薬株式会社 Abcg2多型による薬物輸送能の予測方法

Also Published As

Publication number Publication date
US7541437B2 (en) 2009-06-02
ATE359291T1 (de) 2007-05-15
WO1999040110A1 (en) 1999-08-12
US7655755B2 (en) 2010-02-02
JP4187412B2 (ja) 2008-11-26
EP1054894A1 (de) 2000-11-29
AU755567B2 (en) 2002-12-12
EP1054894B2 (de) 2016-11-09
JP2002502592A (ja) 2002-01-29
EP1054894B1 (de) 2007-04-11
IL137466A (en) 2011-04-28
US20030036645A1 (en) 2003-02-20
ES2284243T5 (es) 2017-08-22
DE69935782T3 (de) 2017-01-05
IL191982A (en) 2011-09-27
IL191982A0 (en) 2008-12-29
AU2761099A (en) 1999-08-23
CA2319715A1 (en) 1999-08-12
EP1054894A4 (de) 2002-03-13
DE69935782T2 (de) 2007-08-16
DE69935782D1 (de) 2007-05-24
US20050272684A1 (en) 2005-12-08
US7741445B2 (en) 2010-06-22
US6313277B1 (en) 2001-11-06
CA2319715C (en) 2012-08-07
IL177612A (en) 2011-04-28
ES2284243T3 (es) 2007-11-01
US20090104199A1 (en) 2009-04-23

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