IL136148A0 - NOVEL 19-NOR STEROIDS SUBSTITUTED IN POSITION 11β, PREPARATION METHOD AND INTERMEDIATES, APPLICATION AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

NOVEL 19-NOR STEROIDS SUBSTITUTED IN POSITION 11β, PREPARATION METHOD AND INTERMEDIATES, APPLICATION AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
IL136148A0
IL136148A0 IL13614898A IL13614898A IL136148A0 IL 136148 A0 IL136148 A0 IL 136148A0 IL 13614898 A IL13614898 A IL 13614898A IL 13614898 A IL13614898 A IL 13614898A IL 136148 A0 IL136148 A0 IL 136148A0
Authority
IL
Israel
Prior art keywords
medicines
intermediates
novel
preparation
application
Prior art date
Application number
IL13614898A
Other languages
English (en)
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of IL136148A0 publication Critical patent/IL136148A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL13614898A 1997-11-17 1998-11-16 NOVEL 19-NOR STEROIDS SUBSTITUTED IN POSITION 11β, PREPARATION METHOD AND INTERMEDIATES, APPLICATION AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM IL136148A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9714357A FR2771096B1 (fr) 1997-11-17 1997-11-17 Nouveaux 19-nor steroides, substitues en position 11beta, procede et intermediaires de preparation, application comme medicaments et compositions pharmaceutiques les renfermant
PCT/FR1998/002437 WO1999025725A1 (fr) 1997-11-17 1998-11-16 NOUVEAUX 19-NOR STEROÏDES SUBSTITUES EN POSITION 11β, PROCEDE ET INTERMEDIAIRES DE PREPARATION, APPLICATION COMME MEDICAMENTS ET COMPOSITIONS PHARMACEUTIQUES LES RENFERMANT

Publications (1)

Publication Number Publication Date
IL136148A0 true IL136148A0 (en) 2001-05-20

Family

ID=9513422

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13614898A IL136148A0 (en) 1997-11-17 1998-11-16 NOVEL 19-NOR STEROIDS SUBSTITUTED IN POSITION 11β, PREPARATION METHOD AND INTERMEDIATES, APPLICATION AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (25)

Country Link
US (2) US6479476B1 (cs)
EP (1) EP1032584B1 (cs)
JP (1) JP4476480B2 (cs)
KR (1) KR20010032127A (cs)
CN (1) CN1286694A (cs)
AR (1) AR016012A1 (cs)
AT (1) ATE232542T1 (cs)
AU (1) AU754846B2 (cs)
BR (1) BR9814201A (cs)
CA (1) CA2309242A1 (cs)
CZ (1) CZ20001799A3 (cs)
DE (1) DE69811393T2 (cs)
EA (1) EA003133B1 (cs)
ES (1) ES2192341T3 (cs)
FR (1) FR2771096B1 (cs)
HR (1) HRP20000315A2 (cs)
HU (1) HUP0100210A3 (cs)
ID (1) ID24236A (cs)
IL (1) IL136148A0 (cs)
NO (1) NO20002483L (cs)
PL (1) PL340381A1 (cs)
SK (1) SK7052000A3 (cs)
TR (1) TR200001405T2 (cs)
WO (1) WO1999025725A1 (cs)
ZA (1) ZA9810358B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2757519B1 (fr) * 1996-12-23 1999-06-11 Hoechst Marion Roussel Inc Steroides substitues en position 11, leur procede de preparation, leur application comme medicament et les compositions pharmaceutiques les renfermant
FR2780060B1 (fr) * 1998-06-23 2000-08-04 Hoechst Marion Roussel Inc Nouveaux 19-nor steroides 17-halogenes, procede et intermediaires de preparation, application comme medicaments et compositions pharmaceutiques les renfermant
DE19929715A1 (de) 1999-06-24 2000-12-28 Schering Ag 11ß-langkettig-substituierte Estratriene, Verfahren zur Herstellung , pharmazeutische Präparate, die diese 11ß-langkettig-substituierten Estratriene enthalten, sowie deren Verwendung zur Herstellung von Arzneimitteln
FR2826004B1 (fr) * 2001-06-13 2008-03-28 Aventis Pharma Sa Procede de preparation de derives estrogenes
FR2854403B1 (fr) * 2003-04-29 2008-07-11 Aventis Pharma Sa Nouveau procede et intermediaires de preparation de composes 19-nor-steroides 17-halogenes
FR2854402B1 (fr) * 2003-04-29 2008-07-04 Aventis Pharma Sa Nouveau procede et intermediaires de preparation de composes 19-nor-steroides
US10400006B2 (en) * 2014-11-26 2019-09-03 The Regents Of The University Of California Estrogen receptor modulators

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4978657A (en) * 1981-01-09 1990-12-18 Roussel Uclaf Novel 11β-substituted-19-nor-steroids
FR2640977A2 (en) * 1982-06-11 1990-06-29 Roussel Uclaf New position-11 substituted 19-norsteroids and their application as medicinal products.
FR2643638B1 (fr) * 1989-02-24 1991-06-14 Roussel Uclaf Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
DE69811393D1 (de) 2003-03-20
EA003133B1 (ru) 2003-02-27
CA2309242A1 (fr) 1999-05-27
JP2001523687A (ja) 2001-11-27
WO1999025725A1 (fr) 1999-05-27
AU754846B2 (en) 2002-11-28
FR2771096A1 (fr) 1999-05-21
ES2192341T3 (es) 2003-10-01
HRP20000315A2 (en) 2000-10-31
CZ20001799A3 (cs) 2001-11-14
FR2771096B1 (fr) 2000-08-11
AR016012A1 (es) 2001-05-30
PL340381A1 (en) 2001-01-29
HUP0100210A1 (hu) 2001-08-28
KR20010032127A (ko) 2001-04-16
DE69811393T2 (de) 2003-08-28
HUP0100210A3 (en) 2001-12-28
JP4476480B2 (ja) 2010-06-09
EP1032584A1 (fr) 2000-09-06
AU1242699A (en) 1999-06-07
CN1286694A (zh) 2001-03-07
SK7052000A3 (en) 2000-12-11
TR200001405T2 (tr) 2001-05-21
ZA9810358B (en) 1999-11-12
US20030073675A1 (en) 2003-04-17
ID24236A (id) 2000-07-13
US6693090B2 (en) 2004-02-17
BR9814201A (pt) 2000-09-26
NO20002483L (no) 2000-07-17
NO20002483D0 (no) 2000-05-12
EP1032584B1 (fr) 2003-02-12
EA200000530A1 (ru) 2000-10-30
ATE232542T1 (de) 2003-02-15
US6479476B1 (en) 2002-11-12

Similar Documents

Publication Publication Date Title
IL136938A0 (en) 11β-HALOGEN-7α-SUBSTITUTED ESTRATRIENES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR THE PREPARATION THEREOF
IL135920A0 (en) 2-aryl -8-oxodihydropurine derivative, process for the preparation thereof, pharmaceutical composition containing the same and intermediate therefor
IL136972A0 (en) Novel anti-estrogenic steroids and associated pharmaceutical compositions and methods of use
HUP0102307A3 (en) Bispidine derivatives, process for their preparation, pharmaceutical compositions thereof and intermediates
HUP0004024A3 (en) Azabenzimidazole-based compounds, process for their preparation and pharmaceutical composition thereof
HUP0001555A3 (en) Tetrahydro-imidazo-naphthyridine derivatives, pharmaceutical compositions thereof and process for their preparation
HUP0001508A3 (en) 4-arylmethylene-2-imino-2,3-dihydrothiazole derivatives, their use, process for the preparation thereof and pharmaceutical compositions containing them
IL123927A (en) Propanolamine derivatives processes for their preparation and pharmaceutical composition comprising them
AU2841199A (en) Novel bis-benzamide derivatives, method for making same pharmaceutical compositions containing them and use thereof as medicine
HUP0100854A3 (en) Cholenic acid amides, process for their preparation and pharmaceutical compositions thereof
HUP0203429A3 (en) Immunomodulatory steroids, in particular the hemihydrate of 16.alpha.-bromoepiandrosterone, process for their preparation and pharmaceutical compositions containing them
IL136148A0 (en) NOVEL 19-NOR STEROIDS SUBSTITUTED IN POSITION 11β, PREPARATION METHOD AND INTERMEDIATES, APPLICATION AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
HUT75112A (en) Oxathiolanes, method for their preparation and pharmaceutical compositions contating same
HRP980196B1 (en) Novel 4-halogenated steroids, preparation method and intermediates, application as medicines and pharmaceutical compositions containing the same
AU8031598A (en) 3-aminoindane derivatives, process for their preparation and pharmaceutical compositions containing them
AU5667898A (en) Steroids substituted in position 11, method of preparation, application as medicines and pharmaceutical compositions containing them
AP2000002007A0 (en) Novel 17-halogenated 19-nor steroids method and intermediates for preparing same use as medicines and pharmaceutical compositions containing same
HUP0001183A3 (en) Pyrrolothiazine and pyrrolothiazepine derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0003463A3 (en) Piperidinylmethyloxazolidinone derivative, process for its preparation pharmaceutical compositions containing it and use thereof
SI1090027T1 (en) Novel 17-halogenated 19-nor steroids, method and intermediates for preparing same, use as medicines and pharmaceutical compositions containing same
HUP0001432A3 (en) Pyrroloazepine derivatives, process for their preparation and pharmaceutical compositions containing them
SI0973793T1 (en) Novel 4- halogenated steroids, preparation method and intermediates, application as medicines and pharmaceutical compositions containing same
AU1167097A (en) 18-methyl 16-methylene 19-nor pregnane derivatives as progestins, pharmaceutical compositions containing them and process for the preparation thereof
SI1042355T1 (en) 11beta-halogen-7alpha-substituted estratrienes, method for producing pharmaceutical preparations containing said 11beta-halogen-7alpha-substituted estratrienes and use of the same for producing medicaments
LV10282B (en) Novel steroids with pregnane skeleton, pharmaceutical compositions containing them and process for preparing same