IL134040A0 - Pyrazine derivatives, their preparation and medicines containing them - Google Patents
Pyrazine derivatives, their preparation and medicines containing themInfo
- Publication number
- IL134040A0 IL134040A0 IL13404098A IL13404098A IL134040A0 IL 134040 A0 IL134040 A0 IL 134040A0 IL 13404098 A IL13404098 A IL 13404098A IL 13404098 A IL13404098 A IL 13404098A IL 134040 A0 IL134040 A0 IL 134040A0
- Authority
- IL
- Israel
- Prior art keywords
- ch2oh
- alk
- choh
- equal
- preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9709058A FR2766187B1 (fr) | 1997-07-17 | 1997-07-17 | Derives de pyrazine, leur preparation et les medicaments les contenant |
| PCT/FR1998/001542 WO1999003844A1 (fr) | 1997-07-17 | 1998-07-15 | Derives de pyrazine, leur preparation et les medicaments les contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL134040A0 true IL134040A0 (en) | 2001-04-30 |
Family
ID=9509300
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13404098A IL134040A0 (en) | 1997-07-17 | 1998-07-15 | Pyrazine derivatives, their preparation and medicines containing them |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6399613B1 (es) |
| EP (1) | EP1001944B1 (es) |
| JP (1) | JP4443036B2 (es) |
| KR (1) | KR20010021901A (es) |
| CN (1) | CN1264371A (es) |
| AT (1) | ATE251144T1 (es) |
| AU (1) | AU747127B2 (es) |
| BR (1) | BR9810880A (es) |
| CA (1) | CA2296727C (es) |
| DE (1) | DE69818679T2 (es) |
| DK (1) | DK1001944T3 (es) |
| ES (1) | ES2205536T3 (es) |
| FR (1) | FR2766187B1 (es) |
| HU (1) | HUP0004602A3 (es) |
| IL (1) | IL134040A0 (es) |
| MX (1) | MXPA00000280A (es) |
| NO (1) | NO20000198D0 (es) |
| NZ (1) | NZ501906A (es) |
| PL (1) | PL338148A1 (es) |
| PT (1) | PT1001944E (es) |
| RU (1) | RU2194703C2 (es) |
| SK (1) | SK482000A3 (es) |
| WO (1) | WO1999003844A1 (es) |
| ZA (1) | ZA986337B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9905771D0 (en) * | 1999-03-12 | 1999-05-05 | Isis Innovation | Compounds |
| US7598278B2 (en) | 2002-04-11 | 2009-10-06 | L'oreal | Administration of pyridinedicarboxylic acid compounds for stimulating or inducing the growth of human keratinous fibers and/or arresting their loss |
| JP2008543953A (ja) * | 2006-04-20 | 2008-12-04 | テバ ファーマシューティカル インダストリーズ リミティド | エスゾピクロン結晶形態ａ、実質的に純粋なエスゾピクロン及び光学的に豊富なエスゾピクロンを調製するための方法 |
| US20080015197A1 (en) * | 2006-06-26 | 2008-01-17 | Alex Mainfeld | Process for the preparatrion of zopiclone |
| WO2008094690A2 (en) * | 2007-01-31 | 2008-08-07 | Teva Pharmaceutical Industries Ltd. | Methods for preparing eszopiclone |
| CN101891679B (zh) * | 2009-05-19 | 2014-04-16 | 上海华明高技术（集团）有限公司 | 吡啶二甲酸与二氨基吡啶质子转移化合物的制备方法 |
| FR3030248B1 (fr) | 2014-12-22 | 2018-03-23 | L'oreal | Association derive d'acide pyridine-dicarboxylique/agent anti-oxydant particulier |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4220650A (en) * | 1978-10-18 | 1980-09-02 | Pfizer Inc. | Organic diamine therapeutic compositions and methods |
| DE3703959A1 (de) * | 1987-02-10 | 1988-08-18 | Hoechst Ag | Pyridin-2,4- und 2,5-dicarbonsaeureamide, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen |
| JPH01117863A (ja) * | 1987-10-30 | 1989-05-10 | Toyobo Co Ltd | 新規なアミド化合物 |
| DE4020570A1 (de) * | 1990-06-28 | 1992-01-02 | Hoechst Ag | 2,4- und 2,5-substituierte pyridin-n-oxide, verfahren zu deren herstellung sowie deren verwendung |
-
1997
- 1997-07-17 FR FR9709058A patent/FR2766187B1/fr not_active Expired - Fee Related
-
1998
- 1998-07-15 PL PL98338148A patent/PL338148A1/xx unknown
- 1998-07-15 HU HU0004602A patent/HUP0004602A3/hu unknown
- 1998-07-15 RU RU2000103449/04A patent/RU2194703C2/ru not_active IP Right Cessation
- 1998-07-15 AU AU88102/98A patent/AU747127B2/en not_active Ceased
- 1998-07-15 CA CA002296727A patent/CA2296727C/fr not_active Expired - Fee Related
- 1998-07-15 KR KR1020007000465A patent/KR20010021901A/ko not_active Application Discontinuation
- 1998-07-15 WO PCT/FR1998/001542 patent/WO1999003844A1/fr not_active Application Discontinuation
- 1998-07-15 CN CN98807199A patent/CN1264371A/zh active Pending
- 1998-07-15 PT PT98939676T patent/PT1001944E/pt unknown
- 1998-07-15 JP JP2000503069A patent/JP4443036B2/ja not_active Expired - Fee Related
- 1998-07-15 IL IL13404098A patent/IL134040A0/xx unknown
- 1998-07-15 BR BR9810880-8A patent/BR9810880A/pt not_active IP Right Cessation
- 1998-07-15 SK SK48-2000A patent/SK482000A3/sk unknown
- 1998-07-15 EP EP98939676A patent/EP1001944B1/fr not_active Expired - Lifetime
- 1998-07-15 ES ES98939676T patent/ES2205536T3/es not_active Expired - Lifetime
- 1998-07-15 MX MXPA00000280A patent/MXPA00000280A/es unknown
- 1998-07-15 AT AT98939676T patent/ATE251144T1/de not_active IP Right Cessation
- 1998-07-15 DK DK98939676T patent/DK1001944T3/da active
- 1998-07-15 NZ NZ501906A patent/NZ501906A/en unknown
- 1998-07-15 DE DE69818679T patent/DE69818679T2/de not_active Expired - Lifetime
- 1998-07-16 ZA ZA986337A patent/ZA986337B/xx unknown
-
2000
- 2000-01-14 NO NO20000198A patent/NO20000198D0/no not_active Application Discontinuation
- 2000-01-14 US US09/483,984 patent/US6399613B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP4443036B2 (ja) | 2010-03-31 |
| NO20000198L (no) | 2000-01-14 |
| AU8810298A (en) | 1999-02-10 |
| NZ501906A (en) | 2002-04-26 |
| PL338148A1 (en) | 2000-09-25 |
| HUP0004602A2 (hu) | 2001-11-28 |
| DE69818679T2 (de) | 2004-07-29 |
| JP2001510188A (ja) | 2001-07-31 |
| BR9810880A (pt) | 2002-05-21 |
| FR2766187B1 (fr) | 2000-06-02 |
| CA2296727A1 (fr) | 1999-01-28 |
| SK482000A3 (en) | 2000-06-12 |
| ATE251144T1 (de) | 2003-10-15 |
| CA2296727C (fr) | 2009-06-09 |
| WO1999003844A1 (fr) | 1999-01-28 |
| NO20000198D0 (no) | 2000-01-14 |
| KR20010021901A (ko) | 2001-03-15 |
| RU2194703C2 (ru) | 2002-12-20 |
| FR2766187A1 (fr) | 1999-01-22 |
| ZA986337B (en) | 1999-01-27 |
| DK1001944T3 (da) | 2004-02-09 |
| CN1264371A (zh) | 2000-08-23 |
| US6399613B1 (en) | 2002-06-04 |
| AU747127B2 (en) | 2002-05-09 |
| DE69818679D1 (de) | 2003-11-06 |
| MXPA00000280A (es) | 2002-04-17 |
| ES2205536T3 (es) | 2004-05-01 |
| EP1001944B1 (fr) | 2003-10-01 |
| PT1001944E (pt) | 2004-02-27 |
| HUP0004602A3 (en) | 2001-12-28 |
| EP1001944A1 (fr) | 2000-05-24 |
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