IL133830A0 - Vertebrate tolomerase genes and proteins and uses thereof - Google Patents
Vertebrate tolomerase genes and proteins and uses thereofInfo
- Publication number
- IL133830A0 IL133830A0 IL13383098A IL13383098A IL133830A0 IL 133830 A0 IL133830 A0 IL 133830A0 IL 13383098 A IL13383098 A IL 13383098A IL 13383098 A IL13383098 A IL 13383098A IL 133830 A0 IL133830 A0 IL 133830A0
- Authority
- IL
- Israel
- Prior art keywords
- tolomerase
- vertebrate
- genes
- proteins
- vertebrate tolomerase
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title 2
- 241000251539 Vertebrata <Metazoa> Species 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5141097P | 1997-07-01 | 1997-07-01 | |
US5301897P | 1997-07-21 | 1997-07-21 | |
US5332997P | 1997-07-21 | 1997-07-21 | |
US5464297P | 1997-08-04 | 1997-08-04 | |
US5828797P | 1997-09-09 | 1997-09-09 | |
PCT/US1998/013835 WO1999001560A1 (en) | 1997-07-01 | 1998-07-01 | Vertebrate telomerase genes and proteins and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
IL133830A0 true IL133830A0 (en) | 2001-04-30 |
Family
ID=27535157
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13383098A IL133830A0 (en) | 1997-07-01 | 1998-07-01 | Vertebrate tolomerase genes and proteins and uses thereof |
Country Status (9)
Country | Link |
---|---|
US (3) | US6916642B1 (xx) |
EP (1) | EP0917579A1 (xx) |
JP (1) | JP2002514928A (xx) |
KR (1) | KR100581990B1 (xx) |
CN (1) | CN1270634A (xx) |
AU (1) | AU748442B2 (xx) |
CA (1) | CA2294782A1 (xx) |
IL (1) | IL133830A0 (xx) |
WO (1) | WO1999001560A1 (xx) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6475789B1 (en) * | 1996-10-01 | 2002-11-05 | University Technology Corporation | Human telomerase catalytic subunit: diagnostic and therapeutic methods |
DE69739497D1 (de) | 1996-10-01 | 2009-08-27 | Geron Corp | Menschlische Telomerase katalytische Untereinheit |
US6808880B2 (en) | 1996-10-01 | 2004-10-26 | Geron Corporation | Method for detecting polynucleotides encoding telomerase |
US6261836B1 (en) | 1996-10-01 | 2001-07-17 | Geron Corporation | Telomerase |
US6093809A (en) | 1996-10-01 | 2000-07-25 | University Technology Corporation | Telomerase |
US6610839B1 (en) * | 1997-08-14 | 2003-08-26 | Geron Corporation | Promoter for telomerase reverse transcriptase |
US7585622B1 (en) | 1996-10-01 | 2009-09-08 | Geron Corporation | Increasing the proliferative capacity of cells using telomerase reverse transcriptase |
US6777203B1 (en) | 1997-11-19 | 2004-08-17 | Geron Corporation | Telomerase promoter driving expression of therapeutic gene sequences |
US7622549B2 (en) | 1997-04-18 | 2009-11-24 | Geron Corporation | Human telomerase reverse transcriptase polypeptides |
JP2002514928A (ja) * | 1997-07-01 | 2002-05-21 | キャンビア バイオシステムス リミティド ライアビリティー カンパニー | 脊椎動物テロメラーゼ遺伝子およびタンパク質ならびにその使用 |
US7378244B2 (en) * | 1997-10-01 | 2008-05-27 | Geron Corporation | Telomerase promoters sequences for screening telomerase modulators |
WO1999027113A1 (en) * | 1997-11-26 | 1999-06-03 | Geron Corporation | Mouse telomerase reverse transcriptase |
US6608188B1 (en) | 1998-01-08 | 2003-08-19 | Chugai Seiyaku Kabushiki Kaisha | CRT-1 gene having reverse transcriptase motif |
US7402307B2 (en) | 1998-03-31 | 2008-07-22 | Geron Corporation | Method for identifying and killing cancer cells |
US6337200B1 (en) | 1998-03-31 | 2002-01-08 | Geron Corporation | Human telomerase catalytic subunit variants |
EP1068296B1 (en) | 1998-03-31 | 2011-08-10 | Geron Corporation | Compositions for eliciting an immune response to a telomerase antigen |
DE19916929A1 (de) | 1999-04-15 | 2000-10-19 | Bayer Ag | Ein automatisierbarer Schnelltest zum Nachweis von Krebserkrankungen auf der Basis von Telomerase(hTC) mRNA mit spezifischen Primern und Sonden |
US6210950B1 (en) * | 1999-05-25 | 2001-04-03 | University Of Medicine And Dentistry Of New Jersey | Methods for diagnosing, preventing, and treating developmental disorders due to a combination of genetic and environmental factors |
US6912492B1 (en) | 1999-05-25 | 2005-06-28 | University Of Medicine & Dentistry Of New Jersey | Methods for diagnosing, preventing, and treating developmental disorders due to a combination of genetic and environmental factors |
US6664046B1 (en) | 1999-12-16 | 2003-12-16 | Roche Molecular Systems, Inc. | Quantitation of hTERT mRNA expression |
KR20010096991A (ko) * | 2000-04-19 | 2001-11-08 | 임정빈 | 텔로머레이즈의 프로모터에 특정하게 결합하는더블유티이1 절편, 그 유전자, 발현벡터 및 그것을 이용한세포성장 억제 방법 |
AUPQ923400A0 (en) * | 2000-08-07 | 2000-08-31 | Children's Medical Research Institute | Assays for alternative lengthening of telomeres |
US7078491B1 (en) | 2000-09-21 | 2006-07-18 | Amgen Inc. | Selective binding agents of telomerase |
GB0031430D0 (en) * | 2000-12-22 | 2001-02-07 | Norsk Hydro As | Polypeptides |
GB0112342D0 (en) * | 2001-05-21 | 2001-07-11 | Norsk Hydro As | Polypeptides |
US20050244969A1 (en) * | 2001-10-18 | 2005-11-03 | Jan-Heiner Kupper | Transient immortalization |
WO2004053116A2 (de) * | 2002-12-06 | 2004-06-24 | Technische Universität Dresden | Gegen htert gerichtete polynucleotide und die verwendung dieser |
EP1748067A1 (en) * | 2005-07-29 | 2007-01-31 | Institut Pasteur | Polynucleotides encoding MHC class I-restricted hTERT epitopes, analogues thereof or polyepitopes |
CA3184778A1 (en) * | 2006-07-28 | 2008-01-31 | The Trustees Of The University Of Pennsylvania | Hiv consensus envelope sequences and methods for using same |
EP1994942A1 (en) * | 2007-05-25 | 2008-11-26 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Pharmaceutical compositions comprising telomerase, and uses thereof |
DK2536830T3 (da) | 2010-02-16 | 2019-10-21 | Ultimovacs As | Polypeptider |
RU2468030C2 (ru) | 2010-04-09 | 2012-11-27 | Государственное учебно-научное учреждение Химический факультет Московского государственного университета им. М.В. Ломоносова | Ингибиторы теломеразы и способ их получения |
JP6466833B2 (ja) | 2012-05-11 | 2019-02-06 | ジェムバックス アンド カエル カンパニー,リミティド | 抗炎症活性を有するペプチド、及びそれを含む組成物 |
WO2013169060A1 (ko) | 2012-05-11 | 2013-11-14 | 주식회사 카엘젬백스 | 패혈증 예방 또는 치료용 조성물 |
WO2014010971A1 (ko) | 2012-07-11 | 2014-01-16 | 주식회사 카엘젬백스 | 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물 |
US20150125438A1 (en) * | 2012-07-20 | 2015-05-07 | Sang Jae Kim | Anti-Inflammatory Peptides and Composition Comprising the Same |
EP2899201B1 (en) * | 2012-09-19 | 2019-09-11 | Gemvax & Kael Co., Ltd. | Cell penetrating peptide, conjugate comprising same, and composition comprising conjugate |
AU2014233711B2 (en) * | 2013-03-15 | 2020-05-28 | Monsanto Technology Llc | Compositions and Methods for the Production and Delivery of RNA |
JP6474786B2 (ja) * | 2013-04-19 | 2019-02-27 | ジェムバックス アンド カエル カンパニー,リミティド | 虚血性損傷の治療及び予防用の組成物 |
CN104508485B (zh) | 2013-06-07 | 2017-01-18 | 杰姆维克斯&凯尔有限公司 | 在癌症免疫疗法中有用的生物标记 |
EP3011967B1 (en) | 2013-06-21 | 2020-06-17 | Gemvax & Kael Co., Ltd. | Hormone secretion regulator, composition containing same, and method for controlling hormone secretion using same |
US9757473B2 (en) * | 2013-07-12 | 2017-09-12 | Gemvax & Kael Co., Ltd. | Cell-penetrating peptide and conjugate comprising same |
ES2773296T3 (es) | 2013-10-23 | 2020-07-10 | Gemvax & Kael Co Ltd | Composición para tratar y prevenir la hiperplasia prostática benigna |
CN105848667B (zh) | 2013-11-22 | 2020-05-19 | 珍白斯凯尔有限公司 | 具有血管生成抑制活性的肽和包含所述肽的组合物 |
JP6367950B2 (ja) | 2013-12-17 | 2018-08-01 | ジェムバックス アンド カエル カンパニー,リミティド | 前立腺癌治療用組成物 |
KR102373603B1 (ko) | 2014-04-11 | 2022-03-14 | 주식회사 젬백스앤카엘 | 섬유증 억제 활성을 가지는 펩티드 및 이를 포함하는 조성물 |
WO2015167067A1 (ko) | 2014-04-30 | 2015-11-05 | 주식회사 카엘젬백스 | 장기, 조직 또는 세포 이식용 조성물, 키트 및 이식 방법 |
KR102413243B1 (ko) | 2014-12-23 | 2022-06-27 | 주식회사 젬백스앤카엘 | 안질환 치료 펩티드 및 이를 포함하는 안질환 치료용 조성물 |
US10835582B2 (en) | 2015-02-27 | 2020-11-17 | Gemvax & Kael Co. Ltd. | Peptide for preventing hearing loss, and composition comprising same |
JP6923453B2 (ja) | 2015-07-02 | 2021-08-18 | ジェムバックス アンド カエル カンパニー,リミティド | 抗ウイルス活性効能を有するペプチド及びこれを含む組成物 |
WO2017070237A1 (en) * | 2015-10-19 | 2017-04-27 | University Of Maryland, Baltimore | Methods for generating engineered human primary blood dendritic cell lines |
WO2017176087A1 (ko) | 2016-04-07 | 2017-10-12 | 주식회사 젬백스앤카엘 | 텔로머라제 활성 증가 및 텔로미어 연장 효능을 가지는 펩티드 및 이를 포함하는 조성물 |
CN110117644A (zh) * | 2019-04-18 | 2019-08-13 | 王金固 | 一种用于生物样本中rna的基因检测方法 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5489508A (en) | 1992-05-13 | 1996-02-06 | University Of Texas System Board Of Regents | Therapy and diagnosis of conditions related to telomere length and/or telomerase activity |
US5639613A (en) | 1992-05-13 | 1997-06-17 | Board Of Regents, University Of Texas System | Methods for cancer diagnosis and prognosis |
US5645986A (en) | 1992-05-13 | 1997-07-08 | Board Of Reagents, The University Of Texas System | Therapy and diagnosis of conditions related to telomere length and/or telomerase activity |
WO1995013382A1 (en) * | 1993-11-12 | 1995-05-18 | Geron Corporation | Therapy and diagnosis of conditions related to telomere length and/or telomerase activity |
NZ289720A (en) * | 1994-07-07 | 1999-03-29 | Geron Corp | Nucleic acids coding for a telomerase, a ribonucleoprotein enzyme involved in telomere synthesis |
US5972605A (en) | 1994-07-07 | 1999-10-26 | Geron Corporation | Assays for regulators of mammalian telomerase expression |
EP0799315A2 (en) * | 1994-12-19 | 1997-10-08 | Cold Spring Harbor Laboratory | Telomerase protein component |
US5770422A (en) | 1996-07-08 | 1998-06-23 | The Regents Of The University Of California | Human telomerase |
US6093809A (en) * | 1996-10-01 | 2000-07-25 | University Technology Corporation | Telomerase |
DE69739497D1 (de) * | 1996-10-01 | 2009-08-27 | Geron Corp | Menschlische Telomerase katalytische Untereinheit |
US6261836B1 (en) | 1996-10-01 | 2001-07-17 | Geron Corporation | Telomerase |
US7390891B1 (en) * | 1996-11-15 | 2008-06-24 | Amgen Inc. | Polynucleotides encoding a telomerase component TP2 |
US5919656A (en) | 1996-11-15 | 1999-07-06 | Amgen Canada Inc. | Genes encoding telomerase protein 1 |
WO1998037181A2 (en) * | 1997-02-20 | 1998-08-27 | Whitehead Institute For Biomedical Research | Telomerase catalytic subunit gene and encoded protein |
JP2002514928A (ja) * | 1997-07-01 | 2002-05-21 | キャンビア バイオシステムス リミティド ライアビリティー カンパニー | 脊椎動物テロメラーゼ遺伝子およびタンパク質ならびにその使用 |
-
1998
- 1998-07-01 JP JP50877199A patent/JP2002514928A/ja not_active Ceased
- 1998-07-01 AU AU82854/98A patent/AU748442B2/en not_active Ceased
- 1998-07-01 KR KR1019997012595A patent/KR100581990B1/ko not_active IP Right Cessation
- 1998-07-01 CA CA002294782A patent/CA2294782A1/en not_active Abandoned
- 1998-07-01 IL IL13383098A patent/IL133830A0/xx unknown
- 1998-07-01 WO PCT/US1998/013835 patent/WO1999001560A1/en not_active Application Discontinuation
- 1998-07-01 CN CN98808383A patent/CN1270634A/zh active Pending
- 1998-07-01 EP EP98933117A patent/EP0917579A1/en not_active Withdrawn
-
2000
- 2000-02-11 US US09/502,424 patent/US6916642B1/en not_active Expired - Fee Related
- 2000-02-11 US US09/502,498 patent/US6846662B1/en not_active Expired - Fee Related
-
2004
- 2004-07-27 US US10/900,231 patent/US20050176022A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR100581990B1 (ko) | 2006-05-23 |
EP0917579A1 (en) | 1999-05-26 |
US20050176022A1 (en) | 2005-08-11 |
US6846662B1 (en) | 2005-01-25 |
JP2002514928A (ja) | 2002-05-21 |
KR20010020601A (ko) | 2001-03-15 |
CN1270634A (zh) | 2000-10-18 |
WO1999001560A1 (en) | 1999-01-14 |
AU8285498A (en) | 1999-01-25 |
CA2294782A1 (en) | 1999-01-14 |
US6916642B1 (en) | 2005-07-12 |
AU748442B2 (en) | 2002-06-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL133830A0 (en) | Vertebrate tolomerase genes and proteins and uses thereof | |
ZA989012B (en) | Chlamydia protein gene sequence and uses thereof | |
AU1088399A (en) | F-box proteins and genes | |
AU9781998A (en) | Huchordin and uses thereof | |
GB9806806D0 (en) | Peptides and uses thereof | |
GB9705903D0 (en) | VP22 Proteins and uses thereof | |
GB9516059D0 (en) | Novel genes and proteins | |
IL136696A0 (en) | Sigirr dna and polypeptides | |
AP2001002189A0 (en) | Genes and proteins and their uses | |
EP1015474A4 (en) | DON-1 GENE, POLYPEPTIDES AND USES THEREOF | |
IL128570A0 (en) | Protein kinases and uses thereof | |
AU9001898A (en) | Beta-fructofuranosidase and gene thereof | |
EP1239039A4 (en) | NEW POLYPEPTIDE AND ENCODING DNA | |
AU3695099A (en) | Ese genes and proteins | |
EP1007675A4 (en) | PORCINE MHC CLASS I GENES AND USES THEREOF | |
HUP0201660A2 (en) | Novel polypeptide and dna thereof | |
GB9714276D0 (en) | Peptides and related compounds | |
IL136988A0 (en) | Novel nucleic acid and polypeptide | |
EP1124840A4 (en) | OVAR-SPECIFIC GENES AND PROTEINS | |
AU8074698A (en) | (costal2) genes and their uses | |
EP0998578A4 (en) | SEL-10 AND USES OF SEL-10 | |
PL341293A1 (en) | Beta-lypothropin and application thereof | |
GB9606272D0 (en) | Gene and peptides | |
EP0965634A4 (en) | NEW PRIMER AND USE | |
EP1142999A4 (en) | PROTEIN AND ITS DNA |