IL133034A0 - 2-Substituted 4,5-diaryl imidazoles - Google Patents

2-Substituted 4,5-diaryl imidazoles

Info

Publication number
IL133034A0
IL133034A0 IL13303498A IL13303498A IL133034A0 IL 133034 A0 IL133034 A0 IL 133034A0 IL 13303498 A IL13303498 A IL 13303498A IL 13303498 A IL13303498 A IL 13303498A IL 133034 A0 IL133034 A0 IL 133034A0
Authority
IL
Israel
Prior art keywords
substituted
diaryl
imidazoles
diaryl imidazoles
Prior art date
Application number
IL13303498A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL133034A0 publication Critical patent/IL133034A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
IL13303498A 1997-06-30 1998-06-26 2-Substituted 4,5-diaryl imidazoles IL133034A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9713726.9A GB9713726D0 (en) 1997-06-30 1997-06-30 Organic compounds
PCT/EP1998/003930 WO1999001449A1 (en) 1997-06-30 1998-06-26 2-substituted 4,5-diaryl imidazoles

Publications (1)

Publication Number Publication Date
IL133034A0 true IL133034A0 (en) 2001-03-19

Family

ID=10815101

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13303498A IL133034A0 (en) 1997-06-30 1998-06-26 2-Substituted 4,5-diaryl imidazoles

Country Status (28)

Country Link
US (1) US6300347B1 (zh)
EP (2) EP0993456B1 (zh)
JP (1) JP3704362B2 (zh)
KR (1) KR20010013215A (zh)
CN (1) CN1261885A (zh)
AR (1) AR014886A1 (zh)
AT (1) ATE275557T1 (zh)
AU (1) AU744411B2 (zh)
BR (1) BR9810955A (zh)
CA (1) CA2291758A1 (zh)
CO (1) CO4940462A1 (zh)
DE (1) DE69826127T2 (zh)
ES (1) ES2226164T3 (zh)
GB (1) GB9713726D0 (zh)
HU (1) HUP0003351A3 (zh)
ID (1) ID23385A (zh)
IL (1) IL133034A0 (zh)
NO (1) NO996429D0 (zh)
NZ (1) NZ501275A (zh)
PE (1) PE99999A1 (zh)
PL (1) PL337057A1 (zh)
PT (1) PT993456E (zh)
RU (1) RU2214408C2 (zh)
SK (1) SK186599A3 (zh)
TR (1) TR199903278T2 (zh)
TW (1) TW429258B (zh)
WO (1) WO1999001449A1 (zh)
ZA (1) ZA985656B (zh)

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ES2254238T3 (es) * 1999-10-27 2006-06-16 Novartis Ag Compuestos de tiazol e imidazo(4,5-b)piridina y su uso farmaceutico.
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US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
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US7612065B2 (en) 2000-04-21 2009-11-03 Vertex Pharmaceuticals Incorporated Inhibitors of c-JUN N-terminal kinases (JNK)
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US7344716B2 (en) * 2003-05-13 2008-03-18 Depuy Spine, Inc. Transdiscal administration of specific inhibitors of pro-inflammatory cytokines
US8273347B2 (en) * 2003-05-13 2012-09-25 Depuy Spine, Inc. Autologous treatment of degenerated disc with cells
US7553827B2 (en) * 2003-08-13 2009-06-30 Depuy Spine, Inc. Transdiscal administration of cycline compounds
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US8361467B2 (en) 2003-07-30 2013-01-29 Depuy Spine, Inc. Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints
CN100471856C (zh) * 2003-07-31 2009-03-25 Irm责任有限公司 作为pdf抑制剂的二环化合物和组合物
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Also Published As

Publication number Publication date
NZ501275A (en) 2002-04-26
ES2226164T3 (es) 2005-03-16
TR199903278T2 (en) 2000-07-21
KR20010013215A (ko) 2001-02-26
DE69826127D1 (de) 2004-10-14
PT993456E (pt) 2005-01-31
ZA985656B (en) 1998-12-30
AU744411B2 (en) 2002-02-21
NO996429L (no) 1999-12-23
PE99999A1 (es) 1999-11-01
NO996429D0 (no) 1999-12-23
GB9713726D0 (en) 1997-09-03
AU8801598A (en) 1999-01-25
AR014886A1 (es) 2001-04-11
EP1396491A2 (en) 2004-03-10
CA2291758A1 (en) 1999-01-14
US6300347B1 (en) 2001-10-09
CN1261885A (zh) 2000-08-02
TW429258B (en) 2001-04-11
WO1999001449A1 (en) 1999-01-14
BR9810955A (pt) 2000-09-26
ID23385A (id) 2000-04-20
RU2214408C2 (ru) 2003-10-20
ATE275557T1 (de) 2004-09-15
EP1396491A3 (en) 2004-06-30
EP0993456B1 (en) 2004-09-08
SK186599A3 (en) 2000-06-12
PL337057A1 (en) 2000-07-31
HUP0003351A3 (en) 2002-01-28
JP2001506280A (ja) 2001-05-15
EP0993456A1 (en) 2000-04-19
HUP0003351A2 (hu) 2001-06-28
JP3704362B2 (ja) 2005-10-12
CO4940462A1 (es) 2000-07-24
DE69826127T2 (de) 2005-09-29

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