IL132584A0 - Generation characterization and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor - Google Patents

Generation characterization and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor

Info

Publication number
IL132584A0
IL132584A0 IL13258498A IL13258498A IL132584A0 IL 132584 A0 IL132584 A0 IL 132584A0 IL 13258498 A IL13258498 A IL 13258498A IL 13258498 A IL13258498 A IL 13258498A IL 132584 A0 IL132584 A0 IL 132584A0
Authority
IL
Israel
Prior art keywords
isolation
stem cells
intermediate precursor
neuroepithelial stem
lineage restricted
Prior art date
Application number
IL13258498A
Other languages
English (en)
Original Assignee
Univ Utah Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Utah Res Found filed Critical Univ Utah Res Found
Publication of IL132584A0 publication Critical patent/IL132584A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0661Smooth muscle cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
    • C12N5/0623Stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/113Acidic fibroblast growth factor (aFGF, FGF-1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/115Basic fibroblast growth factor (bFGF, FGF-2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/135Platelet-derived growth factor [PDGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/155Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/385Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/08Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from cells of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL13258498A 1997-05-07 1998-05-07 Generation characterization and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor IL132584A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/852,744 US6361996B1 (en) 1997-05-07 1997-05-07 Neuroepithelial stem cells and glial-restricted intermediate precursors
US09/073,881 US6830927B2 (en) 1997-05-07 1998-05-06 Common neural progenitor for the CNS and PNS
PCT/US1998/009630 WO1998050526A1 (en) 1997-05-07 1998-05-07 Generation, characterization, and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor
US10/025,333 US7037720B2 (en) 1997-05-07 2001-12-19 Neuroepithelial stem cells and glial-restricted intermediate precursors

Publications (1)

Publication Number Publication Date
IL132584A0 true IL132584A0 (en) 2001-03-19

Family

ID=37057261

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13258498A IL132584A0 (en) 1997-05-07 1998-05-07 Generation characterization and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor

Country Status (7)

Country Link
US (5) US6361996B1 (https=)
EP (1) EP0983344A4 (https=)
JP (1) JP2002513291A (https=)
AU (1) AU751581C (https=)
CA (1) CA2289021C (https=)
IL (1) IL132584A0 (https=)
WO (1) WO1998050526A1 (https=)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8263402B1 (en) * 1998-10-19 2012-09-11 Cornell Research Foundation, Inc. Method for isolating and purifying oligodendrocytes and oligodendrocyte progenitor cells
US7410798B2 (en) 2001-01-10 2008-08-12 Geron Corporation Culture system for rapid expansion of human embryonic stem cells
US6667176B1 (en) 2000-01-11 2003-12-23 Geron Corporation cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells
US20050042749A1 (en) 2001-05-16 2005-02-24 Carpenter Melissa K. Dopaminergic neurons and proliferation-competent precursor cells for treating Parkinson's disease
WO2001088104A2 (en) 2000-05-17 2001-11-22 Geron Corporation Neural progenitor cell populations
US7250294B2 (en) 2000-05-17 2007-07-31 Geron Corporation Screening small molecule drugs using neural cells differentiated from human embryonic stem cells
US6897061B1 (en) * 2000-06-16 2005-05-24 Spinal Cord Society Transdifferentiation of glial cells
WO2003070171A2 (en) 2002-02-15 2003-08-28 Cornell Research Foundation, Inc. Myelination of congenitally dysmyelinated forebrains using oligodendrocyte progenitor cells
US7207743B2 (en) * 2002-05-28 2007-04-24 Polivka Parking Solutions Llc Method and apparatus for constructing an automotive vehicle parking lot
US20050101014A1 (en) 2002-07-11 2005-05-12 Keirstead Hans S. Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury
US7285415B2 (en) 2002-07-11 2007-10-23 The Regents Of The University Of California Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury
AR046076A1 (es) * 2003-07-18 2005-11-23 Otsuka Pharma Co Ltd Procedimiento para obtener una poblacion homogenea de celulas precursoras de oligodendrocitos y poblacion obtenida
US20050153446A1 (en) * 2003-11-07 2005-07-14 Steindler Dennis A. Culturing and differentiating neural precursor cells
CA2560544C (en) 2004-01-16 2015-05-19 Carnegie Mellon University Cellular labeling for nuclear magnetic resonance techniques
NZ551832A (en) * 2004-06-09 2010-01-29 Univ Edinburgh Neural stem cells
CN101106955A (zh) * 2005-01-19 2008-01-16 菲迪亚高级生物聚合物有限公司 用于sci和pnt再生的透明质酸衍生物和神经干细胞
WO2008020815A1 (en) 2006-08-15 2008-02-21 Agency For Science, Technology And Research Mesenchymal stem cell conditioned medium
US7803364B2 (en) * 2005-11-17 2010-09-28 The Cleveland Clinic Foundation Multipotent neural stem cells
WO2008054509A2 (en) * 2006-04-14 2008-05-08 Celsense, Inc. Methods for assessing cell labeling
WO2007120911A2 (en) * 2006-04-14 2007-10-25 Carnegie Mellon University Cellular labeling and quantification for nuclear magnetic resonance techniques
WO2008055244A2 (en) 2006-10-31 2008-05-08 Sensient Colors Inc. Modified pigments and methods for making and using the same
CN101679951B (zh) * 2007-04-17 2013-09-11 罗切斯特大学 端脑胶质限制性细胞群和相关组合物及方法
CA2693678C (en) * 2007-07-10 2017-02-14 Carnegie Mellon University Compositions and methods for producing cellular labels for nuclear magnetic resonance techniques
EP3483222A3 (en) 2007-08-23 2019-08-07 Sensient Colors LLC Self-dispersed pigments and methods for making and using the same
SG188096A1 (en) 2008-01-30 2013-03-28 Geron Corp Synthetic surfaces for culturing stem cell derived oligodendrocyte progenitor cells
JP2011514169A (ja) 2008-03-17 2011-05-06 エージェンシー フォー サイエンス,テクノロジー アンド リサーチ 幹細胞培養のためのマイクロキャリア
US20110110863A1 (en) * 2008-05-02 2011-05-12 Celsense, Inc. Compositions and methods for producing emulsions for nuclear magnetic resonance techniques and other applications
KR20110011658A (ko) 2008-05-08 2011-02-08 유니버시티 오브 로체스터 최적화된 세포 제제에 의한 수초 질환의 치료
US9688956B2 (en) 2008-06-05 2017-06-27 National Cheng Kung University Method for preserving proliferation and differentiation potential of mesenchymal stem cells
US8669048B2 (en) 2008-06-24 2014-03-11 Parkinson's Institute Pluripotent cell lines and methods of use thereof
US20110236356A1 (en) * 2008-12-12 2011-09-29 Nova Southeastern University Methods of isolating and using stem cells
EP3187581A1 (en) 2008-12-23 2017-07-05 BOCO Silicon Valley, Inc. Target populations of oligodendrocyte precursor cells and methods of making and using same
EP2417202A2 (en) 2009-04-07 2012-02-15 Sensient Colors LLC Self-dispersing particles and methods for making and using the same
WO2011011477A1 (en) 2009-07-21 2011-01-27 Abt Holding Company Use of stem cells to reduce leukocyte extravasation
WO2011011500A1 (en) 2009-07-21 2011-01-27 Abt Holding Company Use of stem cells to reduce leukocyte extravasation
WO2011096825A1 (en) * 2010-02-05 2011-08-11 Auckland Uniservices Limited Cell programming
DK2539436T3 (da) 2010-02-25 2021-10-18 Abt Holding Co Modulering af makrofagaktivering
WO2012048276A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
US8433419B2 (en) 2010-10-13 2013-04-30 Cardiac Pacemakers, Inc. Method and apparatus for controlling neurostimulation according to physical state
PL2718416T3 (pl) 2011-06-06 2020-05-18 ReGenesys BVBA Namnażanie komórek macierzystych w bioreaktorach włóknisto-kapilarnych
JP6541577B2 (ja) 2013-02-06 2019-07-10 ユニバーシティー オブ ロチェスター ミエリン障害の治療のための誘導多能性細胞由来オリゴデンドロサイト前駆細胞
EP2970877B1 (en) 2013-03-15 2018-07-25 Wake Forest University Health Sciences Neural progenitor cell differentiation
IL289870B2 (en) 2013-04-12 2023-03-01 Lafrancesca Saverio Improving organs for transplantation
AU2014266935B2 (en) 2013-04-30 2020-06-11 Katholieke Universiteit Leuven Cell therapy for myelodysplastic syndromes
WO2015073913A1 (en) 2013-11-16 2015-05-21 Terumo Bct, Inc. Expanding cells in a bioreactor
US9724432B2 (en) 2015-04-30 2017-08-08 University Of Rochester Non-human mammal model of human degenerative disorder, uses thereof, and method of treating human degenerative disorder
WO2017147212A1 (en) 2016-02-22 2017-08-31 The Regents Of The University Of California Compositions and methods for imaging cell populations
WO2017173064A1 (en) 2016-03-30 2017-10-05 Asterias Biotherapeutics, Inc. Oligodendrocyte progenitor cell compositions
EP4733316A3 (en) * 2017-01-31 2026-05-06 Osaka University Differentiation control method for pluripotent stem cells
US11690876B2 (en) 2017-05-10 2023-07-04 University Of Rochester Methods of treating neuropsychiatric disorders
US12365872B2 (en) 2018-09-19 2025-07-22 Lineage Cell Therapeutics, Inc. Methods for differentiating pluripotent stem cells in dynamic suspension culture
KR20260020476A (ko) * 2019-01-23 2026-02-11 아스테리아스 바이오세라퓨틱스, 인크. 인간 만능 줄기 세포로부터의 배측-유래된 희소돌기아교세포 전구 세포
JP7728747B2 (ja) 2019-08-23 2025-08-25 サナ バイオテクノロジー,インコーポレイテッド Cd24発現細胞およびそれらの用途
KR20220158046A (ko) 2020-03-25 2022-11-29 사나 바이오테크놀로지, 인크. 신경계 장애 및 병태의 치료를 위한 면역저하성 신경 세포
WO2022036150A1 (en) 2020-08-13 2022-02-17 Sana Biotechnology, Inc. Methods of treating sensitized patients with hypoimmunogenic cells, and associated methods and compositions
US20240226164A1 (en) 2021-05-27 2024-07-11 Sana Biotechnology, Inc. Hypoimmunogenic cells comprising engineered hla-e or hla-g
KR20240046319A (ko) 2021-07-14 2024-04-08 사나 바이오테크놀로지, 인크. 저면역원성 세포에서의 y 염색체-연결 항원의 변경된 발현
US20240358761A1 (en) 2021-08-11 2024-10-31 Sana Biotechnology, Inc. Genetically modified cells for allogeneic cell therapy
EP4384598A1 (en) 2021-08-11 2024-06-19 Sana Biotechnology, Inc. Genetically modified cells for allogeneic cell therapy to reduce complement-mediated inflammatory reactions
JP2024535677A (ja) 2021-08-11 2024-10-02 サナ バイオテクノロジー,インコーポレイテッド 即時血液媒介性炎症反応を減少させるための同種細胞療法を目的とした遺伝子改変細胞
AU2022327174A1 (en) 2021-08-11 2024-02-15 Sana Biotechnology, Inc. Inducible systems for altering gene expression in hypoimmunogenic cells
WO2023183313A1 (en) 2022-03-22 2023-09-28 Sana Biotechnology, Inc. Engineering cells with a transgene in b2m or ciita locus and associated compositions and methods
WO2025054202A1 (en) 2023-09-05 2025-03-13 Sana Biotechnology, Inc. Method of screening a sample comprising a transgene with a unique barcode
WO2025151838A1 (en) 2024-01-12 2025-07-17 Sana Biotechnology, Inc. Safety switches to control in vitro and in vivo proliferation of cell therapy products

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5411883A (en) * 1989-12-26 1995-05-02 Somatix Therapy Corporation Proliferated neuron progenitor cell product and process
US5589376A (en) 1992-07-27 1996-12-31 California Institute Of Technology Mammalian neural crest stem cells
NZ256154A (en) * 1992-07-27 1997-02-24 California Inst Of Techn Production of mammalian multipotent neural stem cells, antibodies
US5753506A (en) * 1996-05-23 1998-05-19 Cns Stem Cell Technology, Inc. Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals

Also Published As

Publication number Publication date
WO1998050526A1 (en) 1998-11-12
US7037720B2 (en) 2006-05-02
JP2002513291A (ja) 2002-05-08
EP0983344A1 (en) 2000-03-08
US20020045251A1 (en) 2002-04-18
US6830927B2 (en) 2004-12-14
US20100015702A1 (en) 2010-01-21
AU751581C (en) 2003-06-19
US20060199264A1 (en) 2006-09-07
CA2289021A1 (en) 1998-11-12
AU7481198A (en) 1998-11-27
US7595194B2 (en) 2009-09-29
CA2289021C (en) 2013-07-09
US6361996B1 (en) 2002-03-26
EP0983344A4 (en) 2000-09-27
US20020142460A1 (en) 2002-10-03
AU751581B2 (en) 2002-08-22

Similar Documents

Publication Publication Date Title
IL132584A0 (en) Generation characterization and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor
AU7813401A (en) Isolation and use of solid tumor stem cells
AU3032797A (en) Isolation and characterization of allergen-binding cells for diagnosis of hypersensitivity
GB9608540D0 (en) Isolation of enzymes
IL149043A0 (en) Methods of producing differentiated progenitor cells and lineage-defective embryonic stem cells
GB2318685B (en) Process for manufacture of MOS gated device with self aligned cells
AU8122198A (en) Process for the preparation of methanol and hydrogen
HU9900145D0 (en) Preparation of sterol and stanolesters
AU1478000A (en) (in utero) transplantation of human mesenchymal stem cells
AU2892997A (en) Pluripotent rabbit embryonic stem (es) cell lines and their use in the generation of chimeric rabbits
EP0923642A4 (en) ACTIVE SURVIVAL DOMAINS OF THE IGF-I RECEPTOR AND THEIR USE
AU3557597A (en) The isolation and culture of fetal cells from peripheral maternal blood
AU8140998A (en) Development and use of human pancreatic cell lines
IL146397A0 (en) Ex vivo expansion of mammalian hematopoietic stem cells
IL141585A (en) Numbering of video objects and cells
PL337732A1 (en) Fertilising composition of controllable active ingredients release and method of obtaining same
ZA989077B (en) Isolation of nutrient rich carotenoids and their formulations
AU2998300A (en) Genetically altered mesenchymal stem cells and methods of use thereof
AU1167797A (en) Layout and procedure of charging of batteries
ZA964981B (en) Isolation of naturally occurring isoflavonone and some clinical uses thereof
AU2002309073A1 (en) Generation, characterization, and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor
IL129094A0 (en) Hematopoietic stem cells and methods for generating such cells
AU3594400A (en) Isolation of stem cells and methods of use thereof
AU4188499A (en) Isolation and use of fetal urogenital sinus expressed sequences
PL342011A1 (en) Pharmacological preparations and methods of obtaining them

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees