AU751581C - Generation, characterization, and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor - Google Patents

Generation, characterization, and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor

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Publication number
AU751581C
AU751581C AU74811/98A AU7481198A AU751581C AU 751581 C AU751581 C AU 751581C AU 74811/98 A AU74811/98 A AU 74811/98A AU 7481198 A AU7481198 A AU 7481198A AU 751581 C AU751581 C AU 751581C
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AU
Australia
Prior art keywords
cells
nep
cns
population
cell
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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AU74811/98A
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English (en)
Other versions
AU751581B2 (en
AU7481198A (en
Inventor
Margot Mayer-Proschel
Tahmina Mujtaba
Mahendra S Rao
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University of Utah Research Foundation Inc
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University of Utah Research Foundation Inc
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Application filed by University of Utah Research Foundation Inc filed Critical University of Utah Research Foundation Inc
Publication of AU7481198A publication Critical patent/AU7481198A/en
Publication of AU751581B2 publication Critical patent/AU751581B2/en
Priority to AU2002309073A priority Critical patent/AU2002309073B2/en
Application granted granted Critical
Publication of AU751581C publication Critical patent/AU751581C/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0661Smooth muscle cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
    • C12N5/0623Stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/113Acidic fibroblast growth factor (aFGF, FGF-1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/115Basic fibroblast growth factor (bFGF, FGF-2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/135Platelet-derived growth factor [PDGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/155Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/385Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/08Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from cells of the nervous system

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU74811/98A 1997-05-07 1998-05-07 Generation, characterization, and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor Ceased AU751581C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002309073A AU2002309073B2 (en) 1997-05-07 2002-11-22 Generation, characterization, and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US08/852744 1997-05-07
US08/852,744 US6361996B1 (en) 1997-05-07 1997-05-07 Neuroepithelial stem cells and glial-restricted intermediate precursors
US09/073881 1998-05-06
US09/073,881 US6830927B2 (en) 1997-05-07 1998-05-06 Common neural progenitor for the CNS and PNS
PCT/US1998/009630 WO1998050526A1 (en) 1997-05-07 1998-05-07 Generation, characterization, and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor
US10/025,333 US7037720B2 (en) 1997-05-07 2001-12-19 Neuroepithelial stem cells and glial-restricted intermediate precursors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2002309073A Division AU2002309073B2 (en) 1997-05-07 2002-11-22 Generation, characterization, and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor

Publications (3)

Publication Number Publication Date
AU7481198A AU7481198A (en) 1998-11-27
AU751581B2 AU751581B2 (en) 2002-08-22
AU751581C true AU751581C (en) 2003-06-19

Family

ID=37057261

Family Applications (1)

Application Number Title Priority Date Filing Date
AU74811/98A Ceased AU751581C (en) 1997-05-07 1998-05-07 Generation, characterization, and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor

Country Status (7)

Country Link
US (5) US6361996B1 (https=)
EP (1) EP0983344A4 (https=)
JP (1) JP2002513291A (https=)
AU (1) AU751581C (https=)
CA (1) CA2289021C (https=)
IL (1) IL132584A0 (https=)
WO (1) WO1998050526A1 (https=)

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US6667176B1 (en) 2000-01-11 2003-12-23 Geron Corporation cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells
US20050042749A1 (en) 2001-05-16 2005-02-24 Carpenter Melissa K. Dopaminergic neurons and proliferation-competent precursor cells for treating Parkinson's disease
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US7250294B2 (en) 2000-05-17 2007-07-31 Geron Corporation Screening small molecule drugs using neural cells differentiated from human embryonic stem cells
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AU2003211063A1 (en) 2002-02-15 2003-09-09 Cornell Research Foundation, Inc. Myelination of congenitally dysmyelinated forebrains using oligodendrocyte progenitor cells
US7207743B2 (en) * 2002-05-28 2007-04-24 Polivka Parking Solutions Llc Method and apparatus for constructing an automotive vehicle parking lot
US20050101014A1 (en) 2002-07-11 2005-05-12 Keirstead Hans S. Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury
US7285415B2 (en) 2002-07-11 2007-10-23 The Regents Of The University Of California Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury
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US20050153446A1 (en) * 2003-11-07 2005-07-14 Steindler Dennis A. Culturing and differentiating neural precursor cells
EP1713513B1 (en) 2004-01-16 2014-06-04 Carnegie Mellon University Cellular labeling for nuclear magnetic resonance techniques
CA2569978C (en) * 2004-06-09 2017-06-06 The University Court Of The University Of Edinburgh Neural stem cells
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US7803364B2 (en) 2005-11-17 2010-09-28 The Cleveland Clinic Foundation Multipotent neural stem cells
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US9688956B2 (en) 2008-06-05 2017-06-27 National Cheng Kung University Method for preserving proliferation and differentiation potential of mesenchymal stem cells
US8669048B2 (en) 2008-06-24 2014-03-11 Parkinson's Institute Pluripotent cell lines and methods of use thereof
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US20100158878A1 (en) 2008-12-23 2010-06-24 Alexandra Capela Target populations of oligodendrocyte precursor cells and methods of making and using same
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Also Published As

Publication number Publication date
CA2289021A1 (en) 1998-11-12
AU751581B2 (en) 2002-08-22
EP0983344A1 (en) 2000-03-08
US7595194B2 (en) 2009-09-29
IL132584A0 (en) 2001-03-19
EP0983344A4 (en) 2000-09-27
US20020142460A1 (en) 2002-10-03
US6361996B1 (en) 2002-03-26
US7037720B2 (en) 2006-05-02
US20100015702A1 (en) 2010-01-21
US20060199264A1 (en) 2006-09-07
US6830927B2 (en) 2004-12-14
AU7481198A (en) 1998-11-27
US20020045251A1 (en) 2002-04-18
WO1998050526A1 (en) 1998-11-12
CA2289021C (en) 2013-07-09
JP2002513291A (ja) 2002-05-08

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