IL132571A0 - Ergoline derivatives and ther use as somatostatin receptor antagonists - Google Patents
Ergoline derivatives and ther use as somatostatin receptor antagonistsInfo
- Publication number
- IL132571A0 IL132571A0 IL13257198A IL13257198A IL132571A0 IL 132571 A0 IL132571 A0 IL 132571A0 IL 13257198 A IL13257198 A IL 13257198A IL 13257198 A IL13257198 A IL 13257198A IL 132571 A0 IL132571 A0 IL 132571A0
- Authority
- IL
- Israel
- Prior art keywords
- receptor antagonists
- somatostatin receptor
- ergoline derivatives
- ther use
- ther
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
- C07D457/08—Lysergic acid amides in which the amide nitrogen is a member of a heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9711043.1A GB9711043D0 (en) | 1997-05-29 | 1997-05-29 | Organic compounds |
| PCT/EP1998/003125 WO1998054183A2 (en) | 1997-05-29 | 1998-05-27 | Ergoline derivatives and their use as somatostatin receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL132571A0 true IL132571A0 (en) | 2001-03-19 |
Family
ID=10813201
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13257198A IL132571A0 (en) | 1997-05-29 | 1998-05-27 | Ergoline derivatives and ther use as somatostatin receptor antagonists |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6221870B1 (no) |
| EP (1) | EP0986558A2 (no) |
| JP (1) | JP2001527580A (no) |
| KR (1) | KR20010013103A (no) |
| CN (1) | CN1259946A (no) |
| AR (1) | AR012870A1 (no) |
| AU (1) | AU727841B2 (no) |
| BR (1) | BR9809491A (no) |
| CA (1) | CA2288810A1 (no) |
| CO (1) | CO4950561A1 (no) |
| CZ (1) | CZ289466B6 (no) |
| GB (1) | GB9711043D0 (no) |
| HU (1) | HUP0002311A3 (no) |
| ID (1) | ID22916A (no) |
| IL (1) | IL132571A0 (no) |
| NO (1) | NO995482L (no) |
| NZ (1) | NZ500386A (no) |
| PE (1) | PE74899A1 (no) |
| PL (1) | PL336502A1 (no) |
| RU (1) | RU2191776C2 (no) |
| SK (1) | SK160899A3 (no) |
| TR (1) | TR199902848T2 (no) |
| WO (1) | WO1998054183A2 (no) |
| ZA (1) | ZA984560B (no) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070243240A9 (en) * | 2000-08-24 | 2007-10-18 | Fred Windt-Hanke | Transdermal therapeutic system |
| DE10053397A1 (de) * | 2000-10-20 | 2002-05-02 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
| DE10341317B4 (de) * | 2003-09-03 | 2008-10-23 | Axxonis Pharma Ag | Transdermales therapeutisches System (TTS) zur Verabreichung von Ergolinverbindungen ausgenommen Pergolid |
| DE10066158B4 (de) * | 2000-08-24 | 2007-08-09 | Neurobiotec Gmbh | Verwendung eines transdermalen therapeutischen Systems zur Behandlung des Restless-Legs-Syndroms |
| BR0210915A (pt) * | 2001-06-08 | 2004-06-08 | Sod Conseils Rech Applic | Análogos quiméricos de somatostatina-dopamina |
| FI20031454A0 (fi) | 2003-10-06 | 2003-10-06 | Juvantia Pharma Ltd Oy | Selektiivisiä somatostatiinireseptori 1 ja/tai 4 -agonisteja ja -antagonisteja |
| KR101000923B1 (ko) * | 2004-01-08 | 2010-12-13 | 삼성전자주식회사 | 원격 제어기의 매크로 설정 장치 및 방법 |
| CA2609161A1 (en) * | 2005-05-18 | 2006-11-23 | Siegfried Wurster | Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 |
| JP2007067096A (ja) * | 2005-08-30 | 2007-03-15 | Fujitsu Ltd | 半導体装置 |
| SG181896A1 (en) * | 2009-12-23 | 2012-07-30 | Map Pharmaceuticals Inc | Novel ergoline analogs |
| CA2838991A1 (en) | 2011-06-23 | 2012-12-27 | Map Pharmaceuticals, Inc. | Novel fluoroergoline analogs |
| CA2859173A1 (en) | 2011-12-19 | 2013-06-27 | Map Pharmaceuticals, Inc. | Novel iso-ergoline derivatives |
| SG10201506202RA (en) | 2011-12-21 | 2015-09-29 | Map Pharmaceuticals Inc | Novel neuromodulatory compounds |
| US9012640B2 (en) | 2012-06-22 | 2015-04-21 | Map Pharmaceuticals, Inc. | Cabergoline derivatives |
| WO2014070965A2 (en) | 2012-11-01 | 2014-05-08 | Ipsen Pharma S.A.S | Somatostatin analogs and dimers thereof |
| TWI523863B (zh) | 2012-11-01 | 2016-03-01 | 艾普森藥品公司 | 體抑素－多巴胺嵌合體類似物 |
| MX2017009406A (es) | 2015-01-20 | 2018-01-18 | Xoc Pharmaceuticals Inc | Compuestos de tipo isoergolina y usos de estos. |
| US9657020B2 (en) | 2015-01-20 | 2017-05-23 | Xoc Pharmaceuticals, Inc. | Ergoline compounds and uses thereof |
| WO2018223065A1 (en) | 2017-06-01 | 2018-12-06 | Xoc Pharmaceuticals, Inc. | Ergoline derivatives for use in medicine |
| JP7099717B2 (ja) | 2019-09-30 | 2022-07-12 | 株式会社理研バイオ | ソマトスタチン受容体 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH475252A (de) * | 1966-02-08 | 1969-07-15 | Sandoz Ag | Verfahren zur Herstellung neuer Lysergsäure-Derivate |
| US3592816A (en) | 1966-02-08 | 1971-07-13 | Sandoz Ltd | N-substituted piperazides of lysergic acid |
| GB1188197A (en) | 1967-10-11 | 1970-04-15 | Sandoz Ltd | Lysergic Acid Derivatives |
| NL6818658A (no) * | 1968-01-18 | 1969-07-22 | ||
| GB1580448A (en) * | 1976-12-06 | 1980-12-03 | Farmaceutici Italia | 8 -acetyl-6-methyl-ergoline i derivatives |
| GB8501078D0 (en) * | 1985-01-16 | 1985-02-20 | Erba Farmitalia | Piperazin-1-yl-ergo-line derivatives |
| TW357143B (en) | 1995-07-07 | 1999-05-01 | Novartis Ag | Benzo[g]quinoline derivatives |
-
1997
- 1997-05-29 GB GBGB9711043.1A patent/GB9711043D0/en active Pending
-
1998
- 1998-05-27 RU RU99127433/04A patent/RU2191776C2/ru active
- 1998-05-27 AR ARP980102461A patent/AR012870A1/es unknown
- 1998-05-27 ID IDW991445A patent/ID22916A/id unknown
- 1998-05-27 SK SK1608-99A patent/SK160899A3/sk unknown
- 1998-05-27 EP EP98932090A patent/EP0986558A2/en not_active Withdrawn
- 1998-05-27 WO PCT/EP1998/003125 patent/WO1998054183A2/en not_active Application Discontinuation
- 1998-05-27 US US09/424,377 patent/US6221870B1/en not_active Expired - Fee Related
- 1998-05-27 CN CN98805488A patent/CN1259946A/zh active Pending
- 1998-05-27 CZ CZ19994245A patent/CZ289466B6/cs not_active IP Right Cessation
- 1998-05-27 AU AU82108/98A patent/AU727841B2/en not_active Ceased
- 1998-05-27 JP JP50023799A patent/JP2001527580A/ja active Pending
- 1998-05-27 BR BR9809491-2A patent/BR9809491A/pt not_active IP Right Cessation
- 1998-05-27 PE PE1998000425A patent/PE74899A1/es not_active Application Discontinuation
- 1998-05-27 CA CA002288810A patent/CA2288810A1/en not_active Abandoned
- 1998-05-27 IL IL13257198A patent/IL132571A0/xx unknown
- 1998-05-27 NZ NZ500386A patent/NZ500386A/en unknown
- 1998-05-27 TR TR1999/02848T patent/TR199902848T2/xx unknown
- 1998-05-27 HU HU0002311A patent/HUP0002311A3/hu unknown
- 1998-05-27 KR KR19997011082A patent/KR20010013103A/ko active IP Right Grant
- 1998-05-27 PL PL98336502A patent/PL336502A1/xx unknown
- 1998-05-28 ZA ZA984560A patent/ZA984560B/xx unknown
- 1998-05-28 CO CO98030085A patent/CO4950561A1/es unknown
-
1999
- 1999-11-09 NO NO995482A patent/NO995482L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PL336502A1 (en) | 2000-07-03 |
| CZ289466B6 (cs) | 2002-01-16 |
| US6221870B1 (en) | 2001-04-24 |
| AR012870A1 (es) | 2000-11-22 |
| GB9711043D0 (en) | 1997-07-23 |
| JP2001527580A (ja) | 2001-12-25 |
| HUP0002311A2 (hu) | 2000-12-28 |
| WO1998054183A2 (en) | 1998-12-03 |
| BR9809491A (pt) | 2000-10-17 |
| WO1998054183A3 (en) | 1999-03-04 |
| HUP0002311A3 (en) | 2002-08-28 |
| EP0986558A2 (en) | 2000-03-22 |
| RU2191776C2 (ru) | 2002-10-27 |
| KR20010013103A (ko) | 2001-02-26 |
| NO995482D0 (no) | 1999-11-09 |
| CZ424599A3 (cs) | 2000-03-15 |
| AU727841B2 (en) | 2001-01-04 |
| NO995482L (no) | 1999-11-09 |
| AU8210898A (en) | 1998-12-30 |
| PE74899A1 (es) | 1999-09-14 |
| TR199902848T2 (xx) | 2000-02-21 |
| CN1259946A (zh) | 2000-07-12 |
| CO4950561A1 (es) | 2000-09-01 |
| SK160899A3 (en) | 2000-07-11 |
| NZ500386A (en) | 2002-05-31 |
| CA2288810A1 (en) | 1998-12-03 |
| ID22916A (id) | 1999-12-16 |
| ZA984560B (en) | 1998-11-30 |
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