IL130813A - Process for the preparation of (+/-)3-(3,4-dichlorophenyl)-2-dimethylamino-2-methylpropan-1-ol or cericlamine (inn) and intermediates thereof - Google Patents
Process for the preparation of (+/-)3-(3,4-dichlorophenyl)-2-dimethylamino-2-methylpropan-1-ol or cericlamine (inn) and intermediates thereofInfo
- Publication number
- IL130813A IL130813A IL13081398A IL13081398A IL130813A IL 130813 A IL130813 A IL 130813A IL 13081398 A IL13081398 A IL 13081398A IL 13081398 A IL13081398 A IL 13081398A IL 130813 A IL130813 A IL 130813A
- Authority
- IL
- Israel
- Prior art keywords
- dichlorophenyl
- dimethylamino
- pct
- acid
- cericlamine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9704311A FR2761686B1 (fr) | 1997-04-07 | 1997-04-07 | Nouveau procede de preparation du (+/-)3-(3,4- dichlorophenyl)-2-dimethylamino-2-methyl-propan-1-ol ou cericlamine (inn) |
| PCT/EP1998/002213 WO1998045248A1 (en) | 1997-04-07 | 1998-04-06 | Novel process for the preparation of (+/-)3- (3,4-dichlorophenyl)-2- dimethylamino-2-methylpropan-1-ol or cericlamine (inn) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL130813A0 IL130813A0 (en) | 2001-01-28 |
| IL130813A true IL130813A (en) | 2003-07-06 |
Family
ID=9505666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13081398A IL130813A (en) | 1997-04-07 | 1998-04-06 | Process for the preparation of (+/-)3-(3,4-dichlorophenyl)-2-dimethylamino-2-methylpropan-1-ol or cericlamine (inn) and intermediates thereof |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6121491A (sk) |
| EP (1) | EP0973724B1 (sk) |
| JP (1) | JP2001519799A (sk) |
| KR (1) | KR20010006073A (sk) |
| AT (1) | ATE251116T1 (sk) |
| AU (1) | AU728636B2 (sk) |
| BR (1) | BR9811459A (sk) |
| CA (1) | CA2277874A1 (sk) |
| DE (1) | DE69818653T2 (sk) |
| DK (1) | DK0973724T3 (sk) |
| EA (1) | EA004399B1 (sk) |
| ES (1) | ES2209137T3 (sk) |
| FR (1) | FR2761686B1 (sk) |
| HU (1) | HUP0001753A3 (sk) |
| IL (1) | IL130813A (sk) |
| NZ (1) | NZ337588A (sk) |
| PL (1) | PL336041A1 (sk) |
| PT (1) | PT973724E (sk) |
| SK (1) | SK284184B6 (sk) |
| WO (1) | WO1998045248A1 (sk) |
| ZA (1) | ZA982927B (sk) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1691811B1 (en) | 2003-12-11 | 2014-07-23 | Sunovion Pharmaceuticals Inc. | Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2378746A1 (fr) * | 1977-01-28 | 1978-08-25 | Synthelabo | Derives d'acides a-amines |
| JPS6078921A (ja) * | 1983-10-05 | 1985-05-04 | Toyo Soda Mfg Co Ltd | ハロゲン含有エチルベンゼン誘導体の製造方法 |
| JPS61204150A (ja) * | 1985-03-08 | 1986-09-10 | Sagami Chem Res Center | α―ハロ―α―トリフルオロメチル―β―アリールプロピオン酸 |
| FR2593499B1 (fr) * | 1986-01-30 | 1988-08-12 | Jouveinal Sa | Aminoalcools, leur procede de preparation et leurs applications, notamment en therapeutique |
| US5472970A (en) * | 1992-05-05 | 1995-12-05 | Institut De Recherche Jouveinal S.A. | Allylaminoesters and their application in therapeutics |
| FR2690916B1 (fr) * | 1992-05-05 | 1994-06-17 | Jouveinal Inst Rech | Nouveaux enantiomeres derives du (s)-amino-2-(dichloro-3,4-benzyl)-2-propanol-1. |
-
1997
- 1997-04-07 FR FR9704311A patent/FR2761686B1/fr not_active Expired - Fee Related
-
1998
- 1998-04-06 AT AT98922719T patent/ATE251116T1/de not_active IP Right Cessation
- 1998-04-06 SK SK1360-99A patent/SK284184B6/sk unknown
- 1998-04-06 ZA ZA9802927A patent/ZA982927B/xx unknown
- 1998-04-06 BR BR9811459-0A patent/BR9811459A/pt not_active IP Right Cessation
- 1998-04-06 US US09/381,118 patent/US6121491A/en not_active Expired - Fee Related
- 1998-04-06 AU AU75259/98A patent/AU728636B2/en not_active Ceased
- 1998-04-06 PL PL98336041A patent/PL336041A1/xx unknown
- 1998-04-06 DE DE69818653T patent/DE69818653T2/de not_active Expired - Fee Related
- 1998-04-06 CA CA002277874A patent/CA2277874A1/en not_active Abandoned
- 1998-04-06 WO PCT/EP1998/002213 patent/WO1998045248A1/en not_active Application Discontinuation
- 1998-04-06 HU HU0001753A patent/HUP0001753A3/hu unknown
- 1998-04-06 EP EP98922719A patent/EP0973724B1/en not_active Expired - Lifetime
- 1998-04-06 NZ NZ337588A patent/NZ337588A/xx unknown
- 1998-04-06 JP JP54241598A patent/JP2001519799A/ja active Pending
- 1998-04-06 KR KR1019997009151A patent/KR20010006073A/ko not_active Application Discontinuation
- 1998-04-06 DK DK98922719T patent/DK0973724T3/da active
- 1998-04-06 PT PT98922719T patent/PT973724E/pt unknown
- 1998-04-06 ES ES98922719T patent/ES2209137T3/es not_active Expired - Lifetime
- 1998-04-06 EA EA199900906A patent/EA004399B1/ru not_active IP Right Cessation
- 1998-04-06 IL IL13081398A patent/IL130813A/xx active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EA199900906A1 (ru) | 2000-08-28 |
| IL130813A0 (en) | 2001-01-28 |
| EA004399B1 (ru) | 2004-04-29 |
| BR9811459A (pt) | 2000-09-19 |
| AU7525998A (en) | 1998-10-30 |
| HUP0001753A2 (hu) | 2000-11-28 |
| WO1998045248A1 (en) | 1998-10-15 |
| ATE251116T1 (de) | 2003-10-15 |
| ZA982927B (en) | 1999-07-15 |
| JP2001519799A (ja) | 2001-10-23 |
| EP0973724A1 (en) | 2000-01-26 |
| CA2277874A1 (en) | 1998-10-15 |
| PT973724E (pt) | 2004-02-27 |
| ES2209137T3 (es) | 2004-06-16 |
| SK136099A3 (en) | 2000-05-16 |
| US6121491A (en) | 2000-09-19 |
| FR2761686A1 (fr) | 1998-10-09 |
| KR20010006073A (ko) | 2001-01-15 |
| DE69818653D1 (de) | 2003-11-06 |
| NZ337588A (en) | 2000-05-26 |
| HUP0001753A3 (en) | 2000-12-28 |
| PL336041A1 (en) | 2000-06-05 |
| AU728636B2 (en) | 2001-01-11 |
| DE69818653T2 (de) | 2004-08-19 |
| SK284184B6 (sk) | 2004-10-05 |
| DK0973724T3 (da) | 2004-02-02 |
| FR2761686B1 (fr) | 1999-05-14 |
| EP0973724B1 (en) | 2003-10-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed |