IL130397A - Preparation of Ä1S-Ä1alpha,2beta,3beta,4alpha (S*)ÜÜ-4-Ä7-ÄÄ-3-chloro-2-thienyl)methylÜpropylÜaminoÜ-3H-imidazo Ä4,5-BÜpyridin-3-ylÜ-N-ethyl-2,3 dihydroxycyclopentane carboxamide - Google Patents

Preparation of Ä1S-Ä1alpha,2beta,3beta,4alpha (S*)ÜÜ-4-Ä7-ÄÄ-3-chloro-2-thienyl)methylÜpropylÜaminoÜ-3H-imidazo Ä4,5-BÜpyridin-3-ylÜ-N-ethyl-2,3 dihydroxycyclopentane carboxamide

Info

Publication number
IL130397A
IL130397A IL13039797A IL13039797A IL130397A IL 130397 A IL130397 A IL 130397A IL 13039797 A IL13039797 A IL 13039797A IL 13039797 A IL13039797 A IL 13039797A IL 130397 A IL130397 A IL 130397A
Authority
IL
Israel
Prior art keywords
ä1alpha
ylü
methylüpropylüaminoü
büpyridin
2beta
Prior art date
Application number
IL13039797A
Other languages
English (en)
Other versions
IL130397A0 (en
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Priority to IL15292197A priority Critical patent/IL152921A/en
Publication of IL130397A0 publication Critical patent/IL130397A0/xx
Publication of IL130397A publication Critical patent/IL130397A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/69—Two or more oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
IL13039797A 1996-12-11 1997-11-24 Preparation of Ä1S-Ä1alpha,2beta,3beta,4alpha (S*)ÜÜ-4-Ä7-ÄÄ-3-chloro-2-thienyl)methylÜpropylÜaminoÜ-3H-imidazo Ä4,5-BÜpyridin-3-ylÜ-N-ethyl-2,3 dihydroxycyclopentane carboxamide IL130397A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL15292197A IL152921A (en) 1996-12-11 1997-11-24 Preparation of 4-hydroxy-3-nitro-2(1h)-pyridone from 2-hydroxy-3-cyano-4-methoxypyridine

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3276496P 1996-12-11 1996-12-11
PCT/US1997/021439 WO1998025921A1 (fr) 1996-12-11 1997-11-24 PREPARATION DE [1S-[1a,2b,3b,4a(S*)]]-4-[7-[[1-(3-CHLORO-2-THIENYL) METHYL]PROPYL]AMINO]-3H-IMIDAZO[4,5-b]PYRIDIN-3-YL]-N-ETHYL-2,3-DIHYDROXYCYCLOPENTANECARBOXAMIDE

Publications (2)

Publication Number Publication Date
IL130397A0 IL130397A0 (en) 2000-06-01
IL130397A true IL130397A (en) 2005-11-20

Family

ID=21866680

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13039797A IL130397A (en) 1996-12-11 1997-11-24 Preparation of Ä1S-Ä1alpha,2beta,3beta,4alpha (S*)ÜÜ-4-Ä7-ÄÄ-3-chloro-2-thienyl)methylÜpropylÜaminoÜ-3H-imidazo Ä4,5-BÜpyridin-3-ylÜ-N-ethyl-2,3 dihydroxycyclopentane carboxamide

Country Status (27)

Country Link
US (2) US6143894A (fr)
EP (2) EP0946550B1 (fr)
JP (1) JP2001506626A (fr)
KR (4) KR20060002030A (fr)
CN (3) CN1191251C (fr)
AP (1) AP1063A (fr)
AT (1) ATE301120T1 (fr)
AU (1) AU738581B2 (fr)
BG (1) BG63805B1 (fr)
BR (1) BR9713705A (fr)
CA (1) CA2274630C (fr)
DE (1) DE69733897T2 (fr)
DK (1) DK0946550T3 (fr)
EA (1) EA001989B1 (fr)
ES (1) ES2242984T3 (fr)
HK (2) HK1023998A1 (fr)
HU (1) HUP0000342A3 (fr)
IL (1) IL130397A (fr)
MX (1) MXPA03006730A (fr)
NO (2) NO319722B1 (fr)
OA (1) OA11061A (fr)
PT (1) PT946550E (fr)
SI (1) SI0946550T1 (fr)
SK (1) SK71199A3 (fr)
UA (1) UA54479C2 (fr)
WO (1) WO1998025921A1 (fr)
ZA (1) ZA9711035B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1140933B1 (fr) 1998-12-31 2004-09-08 Aventis Pharmaceuticals Inc. Procede de preparation de derives de deaza-adenosine n6-substitues
US7291603B2 (en) * 2002-07-24 2007-11-06 Ptc Therapeutics, Inc. Nucleoside compounds and their use for treating cancer and diseases associated with somatic mutations
FR2846656B1 (fr) * 2002-11-05 2004-12-24 Servier Lab Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE147074T1 (de) * 1990-09-25 1997-01-15 Rhone Poulenc Rorer Int Verbindungen welche antihypertensive und antiischemische eigenschaften besitzen
US6143743A (en) * 1997-07-03 2000-11-07 Dupont Pharmaceuticals Company Imidazopyrimidines and imidazopyridines for the treatment of neurological disorders
PT1175420E (pt) * 1998-12-21 2003-08-29 Aventis Pharma Inc Processo para a preparacao de derivados n6-substituidos da desaza-adenosina

Also Published As

Publication number Publication date
WO1998025921A1 (fr) 1998-06-18
KR100571690B1 (ko) 2006-04-18
NO20052327L (no) 1999-08-10
US6143894A (en) 2000-11-07
KR100510389B1 (ko) 2005-08-31
SK71199A3 (en) 2000-07-11
HUP0000342A3 (en) 2001-01-29
OA11061A (en) 2002-02-27
EP1609791A1 (fr) 2005-12-28
MXPA03006730A (es) 2003-10-24
EP0946550B1 (fr) 2005-08-03
NO319722B1 (no) 2005-09-05
AP9901550A0 (en) 1999-06-30
EA001989B1 (ru) 2001-10-22
BR9713705A (pt) 2000-05-09
BG63805B1 (bg) 2003-01-31
DK0946550T3 (da) 2005-08-29
NO992795L (no) 1999-08-10
KR20000057505A (ko) 2000-09-15
UA54479C2 (uk) 2003-03-17
AP1063A (en) 2002-04-26
PT946550E (pt) 2005-09-30
EP0946550A4 (fr) 2003-05-14
HUP0000342A2 (hu) 2000-10-28
HK1051862A1 (en) 2003-08-22
IL130397A0 (en) 2000-06-01
KR20050046793A (ko) 2005-05-18
EA199900527A1 (ru) 2000-02-28
EP0946550A1 (fr) 1999-10-06
US6235909B1 (en) 2001-05-22
SI0946550T1 (en) 2005-10-31
DE69733897T2 (de) 2006-06-01
NO992795D0 (no) 1999-06-09
CA2274630C (fr) 2000-10-03
CN1660842A (zh) 2005-08-31
KR20060002030A (ko) 2006-01-06
KR20060002029A (ko) 2006-01-06
AU5360798A (en) 1998-07-03
BG103484A (en) 2000-06-30
CN1394859A (zh) 2003-02-05
NO20052327D0 (no) 2005-05-12
ES2242984T3 (es) 2005-11-16
ATE301120T1 (de) 2005-08-15
DE69733897D1 (de) 2005-09-08
CN1090630C (zh) 2002-09-11
ZA9711035B (en) 1998-06-15
JP2001506626A (ja) 2001-05-22
AU738581B2 (en) 2001-09-20
CN1191251C (zh) 2005-03-02
HK1023998A1 (en) 2000-09-29
CN1240445A (zh) 2000-01-05

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FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees