IL129793A - Process for producing (z)-azabicyclo oxime ethers - Google Patents

Process for producing (z)-azabicyclo oxime ethers

Info

Publication number
IL129793A
IL129793A IL12979397A IL12979397A IL129793A IL 129793 A IL129793 A IL 129793A IL 12979397 A IL12979397 A IL 12979397A IL 12979397 A IL12979397 A IL 12979397A IL 129793 A IL129793 A IL 129793A
Authority
IL
Israel
Prior art keywords
producing
oxime ethers
azabicyclo
azabicyclo oxime
ethers
Prior art date
Application number
IL12979397A
Other languages
English (en)
Other versions
IL129793A0 (en
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of IL129793A0 publication Critical patent/IL129793A0/xx
Publication of IL129793A publication Critical patent/IL129793A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)
IL12979397A 1997-01-27 1997-12-29 Process for producing (z)-azabicyclo oxime ethers IL129793A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3597797P 1997-01-27 1997-01-27
PCT/US1997/023872 WO1998032758A1 (en) 1997-01-27 1997-12-29 Single pot process for producing (z)-azabicyclo oxime ethers

Publications (2)

Publication Number Publication Date
IL129793A0 IL129793A0 (en) 2000-02-29
IL129793A true IL129793A (en) 2003-01-12

Family

ID=21885887

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12979397A IL129793A (en) 1997-01-27 1997-12-29 Process for producing (z)-azabicyclo oxime ethers

Country Status (21)

Country Link
US (1) US6121459A (es)
EP (1) EP1021446A1 (es)
JP (1) JP2001511127A (es)
KR (1) KR20000070464A (es)
AR (1) AR011775A1 (es)
AU (1) AU741566B2 (es)
BR (1) BR9714469A (es)
CA (1) CA2270884A1 (es)
CO (1) CO5011092A1 (es)
GT (1) GT199800019A (es)
HR (1) HRP980040B1 (es)
IL (1) IL129793A (es)
MY (1) MY132840A (es)
NZ (1) NZ335784A (es)
PA (1) PA8445601A1 (es)
PE (1) PE75499A1 (es)
SV (1) SV1998000003A (es)
TW (1) TW533215B (es)
UY (1) UY24857A1 (es)
WO (1) WO1998032758A1 (es)
ZA (1) ZA98618B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5583592B2 (ja) * 2007-11-30 2014-09-03 ニューリンク ジェネティクス コーポレイション Ido阻害剤
FR2938534B1 (fr) 2008-11-14 2012-10-26 Sanofi Aventis Procede de preparation de l'hemifumarate d'eplivanserine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4158015A (en) * 1978-08-16 1979-06-12 Mobil Oil Corporation Process for the stereoselective synthesis of the E isomer of aryl alkyl oximes
US5306718A (en) * 1990-03-06 1994-04-26 Warner-Lambert Company Oxime and amine substituted azabicyclo and azocyclo muscarinic agonists and methods of treatment
IL97266A0 (en) * 1990-03-06 1992-05-25 Warner Lambert Co Azabicyclo and azacyclo oximes and amines,their preparation and pharmaceutical compositions containing them
US5346911A (en) * 1990-03-06 1994-09-13 Warner-Lambert Company Azabicyclo and azacyclo oxime and amine cholinergic agents and methods of treatment
WO1993008191A1 (en) * 1991-10-15 1993-04-29 Warner-Lambert Company Azabicyclo oxime and amine cholinergic agents and methods of treatment
DE4203170A1 (de) * 1992-02-05 1993-08-12 Basf Ag Verfahren zur herstellung von e-oximethern von phenylglyoxylsaeureestern
IL107881A0 (en) * 1992-12-05 1994-04-12 Fisons Corp Furanone derivatives and pharmaceutical compositions containing them
US5514812A (en) * 1994-06-10 1996-05-07 Warner-Lambert Company Preparation of stereochemically pure oximes with muscarinic activity

Also Published As

Publication number Publication date
GT199800019A (es) 1999-07-20
ZA98618B (en) 1998-07-30
US6121459A (en) 2000-09-19
AU741566B2 (en) 2001-12-06
CA2270884A1 (en) 1998-07-30
UY24857A1 (es) 1998-06-25
MY132840A (en) 2007-10-31
JP2001511127A (ja) 2001-08-07
KR20000070464A (ko) 2000-11-25
PE75499A1 (es) 1999-08-20
TW533215B (en) 2003-05-21
WO1998032758A1 (en) 1998-07-30
HRP980040B1 (en) 2002-10-31
NZ335784A (en) 2000-12-22
EP1021446A1 (en) 2000-07-26
CO5011092A1 (es) 2001-02-28
PA8445601A1 (es) 2000-05-24
AU5806598A (en) 1998-08-18
IL129793A0 (en) 2000-02-29
HRP980040A2 (en) 1998-10-31
SV1998000003A (es) 1998-08-13
AR011775A1 (es) 2000-09-13
BR9714469A (pt) 2000-05-16

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed