IL128358A - Neuraminic acid compounds, pharmaceutical compositions containing the same and use thereof - Google Patents
Neuraminic acid compounds, pharmaceutical compositions containing the same and use thereofInfo
- Publication number
- IL128358A IL128358A IL12835897A IL12835897A IL128358A IL 128358 A IL128358 A IL 128358A IL 12835897 A IL12835897 A IL 12835897A IL 12835897 A IL12835897 A IL 12835897A IL 128358 A IL128358 A IL 128358A
- Authority
- IL
- Israel
- Prior art keywords
- neuraminic acid
- same
- hydrogen atom
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- BQINXKOTJQCISL-GRCPKETISA-N keto-neuraminic acid Chemical class OC(=O)C(=O)C[C@H](O)[C@@H](N)[C@@H](O)[C@H](O)[C@H](O)CO BQINXKOTJQCISL-GRCPKETISA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- CERZMXAJYMMUDR-UHFFFAOYSA-N neuraminic acid Natural products NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO CERZMXAJYMMUDR-UHFFFAOYSA-N 0.000 abstract 2
- -1 neuraminic acid compound Chemical class 0.000 abstract 2
- 206010022005 Influenza viral infections Diseases 0.000 abstract 1
- 102000005348 Neuraminidase Human genes 0.000 abstract 1
- 108010006232 Neuraminidase Proteins 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000002148 esters Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Pyrane Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP21345696 | 1996-08-13 | ||
| PCT/JP1997/002810 WO1998006712A1 (en) | 1996-08-13 | 1997-08-12 | Neuraminic acid compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL128358A0 IL128358A0 (en) | 2000-01-31 |
| IL128358A true IL128358A (en) | 2003-04-10 |
Family
ID=16639524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12835897A IL128358A (en) | 1996-08-13 | 1997-08-12 | Neuraminic acid compounds, pharmaceutical compositions containing the same and use thereof |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0934939B1 (es) |
| KR (1) | KR100526666B1 (es) |
| CN (1) | CN1126752C (es) |
| AT (1) | ATE239006T1 (es) |
| AU (1) | AU723994B2 (es) |
| CA (1) | CA2263336C (es) |
| CZ (1) | CZ293041B6 (es) |
| DE (1) | DE69721553T2 (es) |
| DK (1) | DK0934939T3 (es) |
| ES (1) | ES2198002T3 (es) |
| HU (1) | HU226130B1 (es) |
| IL (1) | IL128358A (es) |
| NO (1) | NO319321B1 (es) |
| NZ (1) | NZ334101A (es) |
| PT (1) | PT934939E (es) |
| RU (1) | RU2169145C2 (es) |
| WO (1) | WO1998006712A1 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6518305B1 (en) | 1998-04-23 | 2003-02-11 | Abbott Laboratories | Five-membered carbocyclic and heterocyclic inhibitors of neuraminidases |
| US6593314B1 (en) | 1999-10-19 | 2003-07-15 | Abbott Laboratories | Neuraminidase inhibitors |
| WO2001080892A1 (en) * | 2000-04-25 | 2001-11-01 | Sankyo Company, Limited | Preventives for influenza |
| AUPR001000A0 (en) | 2000-09-08 | 2000-10-05 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
| WO2002076980A1 (en) * | 2001-03-27 | 2002-10-03 | Sankyo Company, Limited | Sialic acid derivatives |
| WO2002092555A1 (en) * | 2001-05-11 | 2002-11-21 | Sankyo Company, Limited | Sialic acid derivatives |
| CA2456239C (en) * | 2001-09-07 | 2010-11-30 | Biota Scientific Management Pty Ltd | Intermediates for preparing neuraminidase inhibitor conjugates |
| RU2237470C1 (ru) * | 2003-01-27 | 2004-10-10 | Купсин Евгений Вениаминович | Комбинированный препарат для устранения симптомов простудных заболеваний и гриппа (варианты) |
| TWI417297B (zh) * | 2007-04-11 | 2013-12-01 | Daiichi Sankyo Co Ltd | 神經胺酸衍生物及其製造方法 |
| CN102532080A (zh) * | 2010-12-29 | 2012-07-04 | 中国科学院上海药物研究所 | 新型唾液酸衍生物及其制备方法,包含该衍生物的药物组合物,以及其用途 |
| EP2678324A1 (en) * | 2011-02-24 | 2014-01-01 | Cadila Healthcare Limited | Process for the preparation of zanamivir |
| RU2520836C1 (ru) * | 2013-02-27 | 2014-06-27 | Александр Васильевич Иващенко | (3r,4r,5s)-4-амино-5-(2,2-дифторацетиламино)-3-(1-этилпропокси)-циклогекс-1-енкарбоновая кислота и ее эфиры, способ их получения и применения |
| CN117243852A (zh) * | 2023-11-01 | 2023-12-19 | 华熙生物科技股份有限公司 | 一种皮肤外用组合物及其用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2000786C1 (ru) * | 1989-07-25 | 1993-10-15 | Научно-исследовательский институт экспериментальной медицины РАМН | Противовирусное средство при гриппозной инфекции |
| AP249A (en) * | 1990-04-24 | 1993-03-17 | Biota Scient Management Pty Ltd | Anti-viral compounds. |
| RU2032683C1 (ru) * | 1991-07-02 | 1995-04-10 | Андрейчиков Юрий Сергеевич | 2-метил-5-метокси-3-метоксалилацетобензофуран, проявляющий противовирусную активность в отношении вируса гриппа типа а и в |
| CA2081068C (en) * | 1991-10-23 | 2005-11-29 | Laurence Mark Von Itzstein | Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of .alpha.-d-neuraminic acid |
| RU2030412C1 (ru) * | 1992-03-04 | 1995-03-10 | Иркутский институт органической химии СО РАН | Способ получения 2-формил-2,5- дибутилтио-2,3- дигидро-4h-пирана |
| AUPM354694A0 (en) * | 1994-01-27 | 1994-02-17 | Biota Scientific Management Pty Ltd | Chemical compounds |
-
1997
- 1997-08-12 HU HU9903632A patent/HU226130B1/hu not_active IP Right Cessation
- 1997-08-12 AT AT97934769T patent/ATE239006T1/de active
- 1997-08-12 WO PCT/JP1997/002810 patent/WO1998006712A1/ja not_active Ceased
- 1997-08-12 PT PT97934769T patent/PT934939E/pt unknown
- 1997-08-12 CN CN97198571A patent/CN1126752C/zh not_active Expired - Fee Related
- 1997-08-12 NZ NZ334101A patent/NZ334101A/en not_active IP Right Cessation
- 1997-08-12 CZ CZ1999365A patent/CZ293041B6/cs not_active IP Right Cessation
- 1997-08-12 DE DE69721553T patent/DE69721553T2/de not_active Expired - Lifetime
- 1997-08-12 EP EP97934769A patent/EP0934939B1/en not_active Expired - Lifetime
- 1997-08-12 ES ES97934769T patent/ES2198002T3/es not_active Expired - Lifetime
- 1997-08-12 KR KR10-1999-7001217A patent/KR100526666B1/ko not_active Expired - Fee Related
- 1997-08-12 IL IL12835897A patent/IL128358A/xx not_active IP Right Cessation
- 1997-08-12 RU RU99105348/04A patent/RU2169145C2/ru not_active IP Right Cessation
- 1997-08-12 DK DK97934769T patent/DK0934939T3/da active
- 1997-08-12 AU AU37858/97A patent/AU723994B2/en not_active Ceased
- 1997-08-12 CA CA002263336A patent/CA2263336C/en not_active Expired - Fee Related
-
1999
- 1999-02-12 NO NO19990672A patent/NO319321B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP9903632A2 (hu) | 2001-08-28 |
| EP0934939A4 (es) | 1999-09-15 |
| ATE239006T1 (de) | 2003-05-15 |
| HUP9903632A3 (en) | 2002-04-29 |
| CN1126752C (zh) | 2003-11-05 |
| CA2263336A1 (en) | 1998-02-19 |
| KR100526666B1 (ko) | 2005-11-08 |
| EP0934939B1 (en) | 2003-05-02 |
| KR20000029971A (ko) | 2000-05-25 |
| ES2198002T3 (es) | 2004-01-16 |
| DE69721553D1 (de) | 2003-06-05 |
| CZ36599A3 (cs) | 1999-06-16 |
| AU3785897A (en) | 1998-03-06 |
| NO990672D0 (no) | 1999-02-12 |
| CZ293041B6 (cs) | 2004-01-14 |
| CN1232461A (zh) | 1999-10-20 |
| NO990672L (no) | 1999-04-13 |
| HU226130B1 (en) | 2008-05-28 |
| PT934939E (pt) | 2003-07-31 |
| EP0934939A1 (en) | 1999-08-11 |
| WO1998006712A1 (en) | 1998-02-19 |
| HK1022687A1 (en) | 2000-08-18 |
| IL128358A0 (en) | 2000-01-31 |
| AU723994B2 (en) | 2000-09-07 |
| DK0934939T3 (da) | 2003-07-21 |
| RU2169145C2 (ru) | 2001-06-20 |
| NZ334101A (en) | 2001-07-27 |
| NO319321B1 (no) | 2005-07-11 |
| DE69721553T2 (de) | 2004-07-22 |
| CA2263336C (en) | 2007-03-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |