IL128318A - Vaccine against malaria - Google Patents

Vaccine against malaria

Info

Publication number
IL128318A
IL128318A IL12831897A IL12831897A IL128318A IL 128318 A IL128318 A IL 128318A IL 12831897 A IL12831897 A IL 12831897A IL 12831897 A IL12831897 A IL 12831897A IL 128318 A IL128318 A IL 128318A
Authority
IL
Israel
Prior art keywords
vaccine composition
protein
falciparum
proteins
composition according
Prior art date
Application number
IL12831897A
Other languages
English (en)
Hebrew (he)
Other versions
IL128318A0 (en
Original Assignee
Smithkline Beecham Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Biolog filed Critical Smithkline Beecham Biolog
Publication of IL128318A0 publication Critical patent/IL128318A0/xx
Publication of IL128318A publication Critical patent/IL128318A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/002Protozoa antigens
    • A61K39/015Hemosporidia antigens, e.g. Plasmodium antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL12831897A 1996-08-02 1997-07-31 Vaccine against malaria IL128318A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9616351.4A GB9616351D0 (en) 1996-08-02 1996-08-02 Vaccine composition
PCT/EP1997/004326 WO1998005355A1 (en) 1996-08-02 1997-07-31 Vaccine composition against malaria

Publications (2)

Publication Number Publication Date
IL128318A0 IL128318A0 (en) 2000-01-31
IL128318A true IL128318A (en) 2002-04-21

Family

ID=10797980

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12831897A IL128318A (en) 1996-08-02 1997-07-31 Vaccine against malaria

Country Status (32)

Country Link
US (2) US20020172692A1 (ru)
EP (2) EP0957933B1 (ru)
JP (1) JP2000517295A (ru)
KR (1) KR20000029747A (ru)
CN (1) CN1241639C (ru)
AP (1) AP1166A (ru)
AR (1) AR008799A1 (ru)
AT (1) ATE394119T1 (ru)
AU (1) AU706303B2 (ru)
BG (1) BG63290B1 (ru)
BR (1) BR9710913A (ru)
CA (1) CA2262402A1 (ru)
CO (1) CO4650186A1 (ru)
CZ (1) CZ290826B6 (ru)
DE (1) DE69738672D1 (ru)
DZ (1) DZ2283A1 (ru)
EA (1) EA002167B1 (ru)
GB (1) GB9616351D0 (ru)
ID (1) ID17860A (ru)
IL (1) IL128318A (ru)
MA (1) MA24291A1 (ru)
MY (1) MY116128A (ru)
NO (1) NO319844B1 (ru)
OA (1) OA10969A (ru)
PE (1) PE97298A1 (ru)
PL (1) PL188741B1 (ru)
SK (1) SK282438B6 (ru)
TR (1) TR199900195T2 (ru)
UA (1) UA68336C2 (ru)
UY (1) UY24654A1 (ru)
WO (1) WO1998005355A1 (ru)
ZA (1) ZA976815B (ru)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9915204D0 (en) * 1999-06-29 1999-09-01 Smithkline Beecham Biolog Vaccine
CA2502268A1 (en) 2002-10-23 2004-05-06 Glaxosmithkline Biologicals S.A. Methods for vaccinating against malaria
NZ584979A (en) * 2003-12-01 2010-10-29 Meiji Dairies Corp Peptide inhibiting angiotensin converting enzyme
GB0513421D0 (en) * 2005-06-30 2005-08-03 Glaxosmithkline Biolog Sa Vaccines
MX2008001527A (es) * 2005-08-02 2008-04-04 Novartis Vaccines & Diagnostic Reduccion de interferencia entre adyuvantes que contienen aceite y antigenos que contienen agentes tensioactivos.
US9592282B2 (en) * 2006-07-18 2017-03-14 Glaxosmithkline Biologicals Sa Vaccines for malaria
GB0614254D0 (en) * 2006-07-18 2006-08-30 Smithkline Beecham Biolog Vaccine
ATE511398T1 (de) 2006-09-07 2011-06-15 Glaxosmithkline Biolog Sa Inaktiviertes poliovirus mischimpfstoff
AR067905A1 (es) 2007-08-13 2009-10-28 Glaxosmithkline Biolog Sa Vacunas
WO2009080715A2 (en) * 2007-12-21 2009-07-02 Glaxosmithkline Biologicals S.A. Vaccines for malaria
CN101951947A (zh) * 2007-12-24 2011-01-19 葛兰素史密丝克莱恩生物有限公司 疟疾疫苗
EP2313108A4 (en) * 2008-06-30 2013-06-12 Us Army As Represented By The Secretary Of The Army ANTIPALUDE VACCINE OF SELF-ASSEMBLED POLYPEPTIDE NANOPARTICLES
EP2451478A4 (en) * 2009-11-05 2013-11-20 Us Navy PLASMODIUM FALCIPARUM SPOROZOITE AND LIVERPHASE ANTIGENS THEREWITH
US9168292B2 (en) 2010-09-27 2015-10-27 Crucell Holland B.V. Heterologous prime boost vaccination regimen against malaria
GB201116248D0 (en) 2011-09-20 2011-11-02 Glaxosmithkline Biolog Sa Liposome production using isopropanol
US20130122038A1 (en) 2011-11-14 2013-05-16 The United States Of America As Represented By The Secretary Of The Department Heterologous prime-boost immunization using measles virus-based vaccines
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
CN104338129B (zh) * 2013-07-26 2017-05-24 中国科学院上海巴斯德研究所 雷帕霉素作为疫苗佐剂的用途及制备方法
US10695424B2 (en) 2016-12-07 2020-06-30 Glaxosmithkline Biologicals S.A. Method of making a liposome composition
GB201621686D0 (en) 2016-12-20 2017-02-01 Glaxosmithkline Biologicals Sa Novel methods for inducing an immune response
CN111032080A (zh) 2017-05-30 2020-04-17 葛兰素史密丝克莱恩生物有限公司 用于制造佐剂的新型方法
BR112020010790A2 (pt) 2017-12-01 2020-11-10 Glaxosmithkline Biologicals S.A. purificação da saponina
US20220235095A1 (en) 2019-06-05 2022-07-28 Glaxosmithkline Biologicals Sa Saponin purification

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0071705B1 (en) * 1981-05-21 1989-11-23 The Wellcome Foundation Limited Protozoal antigen
ES8800273A1 (es) * 1985-03-28 1987-11-01 Univ New York Perfeccionamientos en la fabricacion de conjugados de proteinas portadores de antigenos inmunogenicos para vacunas contra la malaria
GB8819209D0 (en) * 1988-08-12 1988-09-14 Research Corp Ltd Polypeptide & dna encoding same
GB9012580D0 (en) * 1990-06-06 1990-07-25 Univ Nijmegen Novel protein
FR2679776A1 (fr) * 1991-07-31 1993-02-05 Pasteur Institut Melange de constituants peptidiques ayant des proprietes vaccinantes contre le paludisme, notamment du a plasmodium falciparum.
KR100251505B1 (ko) * 1991-11-16 2000-05-01 장 스테판느 말라리아원충으로부터의 cs 및 hbsag 사이의 혼성 단백질(hybrid protein between cs from plasmodium and hbsag)
US6169171B1 (en) * 1992-02-27 2001-01-02 Smithkline Beecham Biologicals (S.A.) Hybrid protein between CS from plasmodium and HBSAG
SG90042A1 (en) * 1992-06-25 2002-07-23 Smithkline Beecham Biolog Vaccine composition containing adjuvants
GB9326253D0 (en) * 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines
AUPM368994A0 (en) * 1994-02-04 1994-02-24 Saramane Pty Ltd Malaria merozoite antigen subunit vaccine
FR2744724B1 (fr) * 1996-02-14 2002-08-02 Pasteur Institut Proteine recombinante contenant un fragment c-terminal de la proteine msp-1 d'un plasmodium infectieux pour l'homme pour la production de vaccins anti-paludiques
FR2744723A1 (fr) * 1996-02-14 1997-08-14 Pasteur Institut Proteine recombinante contenant un fragment c-terminal d'une proteine msp-1 d'un plasmodium infectieux pour l'homme pour la production de vaccins anti-paludiques

Also Published As

Publication number Publication date
OA10969A (en) 2003-03-04
AU706303B2 (en) 1999-06-10
UY24654A1 (es) 2001-08-27
IL128318A0 (en) 2000-01-31
BG103141A (en) 1999-08-31
AU4204097A (en) 1998-02-25
CN1231613A (zh) 1999-10-13
AP1166A (en) 2003-06-30
PL188741B1 (pl) 2005-04-29
EP0957933A1 (en) 1999-11-24
NO319844B1 (no) 2005-09-19
CO4650186A1 (es) 1998-09-03
CZ290826B6 (cs) 2002-10-16
CZ29299A3 (cs) 1999-06-16
ATE394119T1 (de) 2008-05-15
CN1241639C (zh) 2006-02-15
PE97298A1 (es) 1999-02-14
GB9616351D0 (en) 1996-09-11
JP2000517295A (ja) 2000-12-26
MY116128A (en) 2003-11-28
US20020172692A1 (en) 2002-11-21
EP1623720A3 (en) 2006-02-22
EA199900069A1 (ru) 1999-10-28
ID17860A (id) 1998-01-29
WO1998005355A1 (en) 1998-02-12
BR9710913A (pt) 1999-08-17
AP9901448A0 (en) 1999-03-31
TR199900195T2 (xx) 1999-04-21
CA2262402A1 (en) 1998-02-12
DZ2283A1 (fr) 2002-12-25
ZA976815B (en) 1998-05-11
NO990464D0 (no) 1999-02-01
EA002167B1 (ru) 2002-02-28
SK282438B6 (sk) 2002-02-05
UA68336C2 (en) 2004-08-16
DE69738672D1 (de) 2008-06-19
US20060292170A1 (en) 2006-12-28
EP0957933B1 (en) 2008-05-07
KR20000029747A (ko) 2000-05-25
EP1623720A2 (en) 2006-02-08
MA24291A1 (fr) 1998-04-01
SK11599A3 (en) 2000-03-13
NO990464L (no) 1999-02-01
PL331424A1 (en) 1999-07-19
BG63290B1 (bg) 2001-09-28
AR008799A1 (es) 2000-02-23

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Legal Events

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KB Patent renewed
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MM9K Patent not in force due to non-payment of renewal fees