IL128264A0 - Process for the production of alkoxycarbonyldipeptides intermediates in the synthesis of the lisinopril - Google Patents

Process for the production of alkoxycarbonyldipeptides intermediates in the synthesis of the lisinopril

Info

Publication number
IL128264A0
IL128264A0 IL12826499A IL12826499A IL128264A0 IL 128264 A0 IL128264 A0 IL 128264A0 IL 12826499 A IL12826499 A IL 12826499A IL 12826499 A IL12826499 A IL 12826499A IL 128264 A0 IL128264 A0 IL 128264A0
Authority
IL
Israel
Prior art keywords
alkoxycarbonyldipeptides
lisinopril
intermediates
synthesis
production
Prior art date
Application number
IL12826499A
Other languages
English (en)
Original Assignee
Pfc Italiana Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfc Italiana Srl filed Critical Pfc Italiana Srl
Publication of IL128264A0 publication Critical patent/IL128264A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/064General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for omega-amino or -guanidino functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/08General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06086Dipeptides with the first amino acid being basic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL12826499A 1998-02-09 1999-01-28 Process for the production of alkoxycarbonyldipeptides intermediates in the synthesis of the lisinopril IL128264A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT98BO000063A IT1299341B1 (it) 1998-02-09 1998-02-09 Processo per la produzione di alcossicarbonildipeptidi intermedi nella sintesi del lisinopril.

Publications (1)

Publication Number Publication Date
IL128264A0 true IL128264A0 (en) 2000-02-17

Family

ID=11342848

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12826499A IL128264A0 (en) 1998-02-09 1999-01-28 Process for the production of alkoxycarbonyldipeptides intermediates in the synthesis of the lisinopril

Country Status (10)

Country Link
US (2) US6031112A (fr)
EP (1) EP0943621A3 (fr)
JP (1) JPH11269196A (fr)
BR (1) BR9900439A (fr)
CA (1) CA2260450A1 (fr)
HU (1) HUP9900153A3 (fr)
IL (1) IL128264A0 (fr)
IT (1) IT1299341B1 (fr)
TR (1) TR199900247A3 (fr)
ZA (1) ZA99534B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1307265B1 (it) * 1999-08-09 2001-10-30 P F C Italiana Srl Speciality Procedimento per la preparazione di prodotti intermedi nella sintesidi lisinopril.
IT1318623B1 (it) * 2000-07-13 2003-08-27 Isagro Ricerca Srl Procedimento per la preparazione di derivati dipeptidici.
US6462174B1 (en) 2001-06-25 2002-10-08 Astrazeneca Ab Amorphous compound
US6627760B1 (en) 2001-06-25 2003-09-30 Astrazeneca Ab Amorphous compound
US6458769B1 (en) 2001-06-25 2002-10-01 Astrazeneca Ab Amorphous compound
FR2916444B1 (fr) * 2007-05-25 2011-02-11 Sanofi Aventis Procede de preparation de n-carboxyanhydride enantiomeriquement enrichi.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1290141A (fr) * 1968-05-31 1972-09-20
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
EP0168769A3 (fr) * 1984-07-16 1989-02-08 Merck & Co. Inc. Procédé de préparation de carboxyalkyl dipeptides
JPH01254651A (ja) * 1988-04-04 1989-10-11 Kanegafuchi Chem Ind Co Ltd N↑2−(1−カルボキシ−3−フエニルプロピル)−l−リジン誘導体及び該化合物を用いるリジノプリルの製造法
SI9200213A (en) * 1992-09-16 1994-03-31 Krka Process for preparing alkyl-l-alanil-l-proline derivates

Also Published As

Publication number Publication date
EP0943621A3 (fr) 2001-12-12
HUP9900153A3 (en) 2002-02-28
ZA99534B (en) 1999-07-26
IT1299341B1 (it) 2000-03-16
US6031112A (en) 2000-02-29
HUP9900153A2 (hu) 1999-11-29
JPH11269196A (ja) 1999-10-05
ITBO980063A0 (it) 1998-02-09
CA2260450A1 (fr) 1999-08-09
ITBO980063A1 (it) 1999-08-09
US6166217A (en) 2000-12-26
BR9900439A (pt) 2000-05-09
TR199900247A2 (xx) 2001-02-21
TR199900247A3 (tr) 2001-02-21
EP0943621A2 (fr) 1999-09-22
HU9900153D0 (en) 1999-03-29

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