HUP9900153A3 - Process for producing alkoxycarbonyldipeptides intermediates in the synthesis of the lisinopril - Google Patents
Process for producing alkoxycarbonyldipeptides intermediates in the synthesis of the lisinoprilInfo
- Publication number
- HUP9900153A3 HUP9900153A3 HU9900153A HUP9900153A HUP9900153A3 HU P9900153 A3 HUP9900153 A3 HU P9900153A3 HU 9900153 A HU9900153 A HU 9900153A HU P9900153 A HUP9900153 A HU P9900153A HU P9900153 A3 HUP9900153 A3 HU P9900153A3
- Authority
- HU
- Hungary
- Prior art keywords
- alkoxycarbonyldipeptides
- lisinopril
- intermediates
- synthesis
- producing
- Prior art date
Links
- 108010007859 Lisinopril Proteins 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- RLAWWYSOJDYHDC-BZSNNMDCSA-N lisinopril Chemical compound C([C@H](N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(O)=O)C(O)=O)CC1=CC=CC=C1 RLAWWYSOJDYHDC-BZSNNMDCSA-N 0.000 title 1
- 229960002394 lisinopril Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/064—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for omega-amino or -guanidino functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT98BO000063A IT1299341B1 (it) | 1998-02-09 | 1998-02-09 | Processo per la produzione di alcossicarbonildipeptidi intermedi nella sintesi del lisinopril. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU9900153D0 HU9900153D0 (en) | 1999-03-29 |
| HUP9900153A2 HUP9900153A2 (hu) | 1999-11-29 |
| HUP9900153A3 true HUP9900153A3 (en) | 2002-02-28 |
Family
ID=11342848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9900153A HUP9900153A3 (en) | 1998-02-09 | 1999-01-20 | Process for producing alkoxycarbonyldipeptides intermediates in the synthesis of the lisinopril |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6031112A (hu) |
| EP (1) | EP0943621A3 (hu) |
| JP (1) | JPH11269196A (hu) |
| BR (1) | BR9900439A (hu) |
| CA (1) | CA2260450A1 (hu) |
| HU (1) | HUP9900153A3 (hu) |
| IL (1) | IL128264A0 (hu) |
| IT (1) | IT1299341B1 (hu) |
| TR (1) | TR199900247A3 (hu) |
| ZA (1) | ZA99534B (hu) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1307265B1 (it) * | 1999-08-09 | 2001-10-30 | P F C Italiana Srl Speciality | Procedimento per la preparazione di prodotti intermedi nella sintesidi lisinopril. |
| IT1318623B1 (it) * | 2000-07-13 | 2003-08-27 | Isagro Ricerca Srl | Procedimento per la preparazione di derivati dipeptidici. |
| US6462174B1 (en) | 2001-06-25 | 2002-10-08 | Astrazeneca Ab | Amorphous compound |
| US6627760B1 (en) | 2001-06-25 | 2003-09-30 | Astrazeneca Ab | Amorphous compound |
| US6458769B1 (en) | 2001-06-25 | 2002-10-01 | Astrazeneca Ab | Amorphous compound |
| FR2916444B1 (fr) * | 2007-05-25 | 2011-02-11 | Sanofi Aventis | Procede de preparation de n-carboxyanhydride enantiomeriquement enrichi. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1290141A (hu) * | 1968-05-31 | 1972-09-20 | ||
| IL58849A (en) * | 1978-12-11 | 1983-03-31 | Merck & Co Inc | Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them |
| EP0168769A3 (en) * | 1984-07-16 | 1989-02-08 | Merck & Co. Inc. | Process for preparing carboxyalkyl dipeptides |
| JPH01254651A (ja) * | 1988-04-04 | 1989-10-11 | Kanegafuchi Chem Ind Co Ltd | Ｎ↑２−（１−カルボキシ−３−フエニルプロピル）−ｌ−リジン誘導体及び該化合物を用いるリジノプリルの製造法 |
| SI9200213A (en) * | 1992-09-16 | 1994-03-31 | Krka | Process for preparing alkyl-l-alanil-l-proline derivates |
-
1998
- 1998-02-09 IT IT98BO000063A patent/IT1299341B1/it active IP Right Grant
-
1999
- 1999-01-19 EP EP99101015A patent/EP0943621A3/en not_active Withdrawn
- 1999-01-20 HU HU9900153A patent/HUP9900153A3/hu unknown
- 1999-01-25 ZA ZA9900534A patent/ZA99534B/xx unknown
- 1999-01-25 US US09/237,071 patent/US6031112A/en not_active Expired - Fee Related
- 1999-01-27 CA CA002260450A patent/CA2260450A1/en not_active Abandoned
- 1999-01-28 IL IL12826499A patent/IL128264A0/xx unknown
- 1999-02-05 TR TR1999/00247A patent/TR199900247A3/tr unknown
- 1999-02-08 JP JP11030618A patent/JPH11269196A/ja active Pending
- 1999-02-08 BR BR9900439-9A patent/BR9900439A/pt not_active Application Discontinuation
- 1999-06-18 US US09/335,811 patent/US6166217A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0943621A3 (en) | 2001-12-12 |
| ZA99534B (en) | 1999-07-26 |
| IT1299341B1 (it) | 2000-03-16 |
| US6031112A (en) | 2000-02-29 |
| HUP9900153A2 (hu) | 1999-11-29 |
| JPH11269196A (ja) | 1999-10-05 |
| ITBO980063A0 (it) | 1998-02-09 |
| CA2260450A1 (en) | 1999-08-09 |
| ITBO980063A1 (it) | 1999-08-09 |
| US6166217A (en) | 2000-12-26 |
| BR9900439A (pt) | 2000-05-09 |
| TR199900247A2 (xx) | 2001-02-21 |
| TR199900247A3 (tr) | 2001-02-21 |
| EP0943621A2 (en) | 1999-09-22 |
| HU9900153D0 (en) | 1999-03-29 |
| IL128264A0 (en) | 2000-02-17 |
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