ZA99534B - Process for the production of alkoxycarbonyldipeptides intermediates in the synthesis of the lisinopril. - Google Patents

Process for the production of alkoxycarbonyldipeptides intermediates in the synthesis of the lisinopril.

Info

Publication number
ZA99534B
ZA99534B ZA9900534A ZA99534A ZA99534B ZA 99534 B ZA99534 B ZA 99534B ZA 9900534 A ZA9900534 A ZA 9900534A ZA 99534 A ZA99534 A ZA 99534A ZA 99534 B ZA99534 B ZA 99534B
Authority
ZA
South Africa
Prior art keywords
alkoxycarbonyldipeptides
lisinopril
intermediates
synthesis
production
Prior art date
Application number
ZA9900534A
Other languages
English (en)
Inventor
Vincenzo Cannata
Valeriano Merli
Stefano Saguatti
Original Assignee
P F C Italiana S R I
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by P F C Italiana S R I filed Critical P F C Italiana S R I
Publication of ZA99534B publication Critical patent/ZA99534B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/064—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for omega-amino or -guanidino functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA9900534A 1998-02-09 1999-01-25 Process for the production of alkoxycarbonyldipeptides intermediates in the synthesis of the lisinopril. ZA99534B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT98BO000063A IT1299341B1 (it) 1998-02-09 1998-02-09 Processo per la produzione di alcossicarbonildipeptidi intermedi nella sintesi del lisinopril.

Publications (1)

Publication Number Publication Date
ZA99534B true ZA99534B (en) 1999-07-26

Family

ID=11342848

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9900534A ZA99534B (en) 1998-02-09 1999-01-25 Process for the production of alkoxycarbonyldipeptides intermediates in the synthesis of the lisinopril.

Country Status (10)

Country Link
US (2) US6031112A (xx)
EP (1) EP0943621A3 (xx)
JP (1) JPH11269196A (xx)
BR (1) BR9900439A (xx)
CA (1) CA2260450A1 (xx)
HU (1) HUP9900153A3 (xx)
IL (1) IL128264A0 (xx)
IT (1) IT1299341B1 (xx)
TR (1) TR199900247A3 (xx)
ZA (1) ZA99534B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1307265B1 (it) * 1999-08-09 2001-10-30 P F C Italiana Srl Speciality Procedimento per la preparazione di prodotti intermedi nella sintesidi lisinopril.
IT1318623B1 (it) * 2000-07-13 2003-08-27 Isagro Ricerca Srl Procedimento per la preparazione di derivati dipeptidici.
US6462174B1 (en) 2001-06-25 2002-10-08 Astrazeneca Ab Amorphous compound
US6627760B1 (en) 2001-06-25 2003-09-30 Astrazeneca Ab Amorphous compound
US6458769B1 (en) 2001-06-25 2002-10-01 Astrazeneca Ab Amorphous compound
FR2916444B1 (fr) * 2007-05-25 2011-02-11 Sanofi Aventis Procede de preparation de n-carboxyanhydride enantiomeriquement enrichi.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1290141A (xx) * 1968-05-31 1972-09-20
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
EP0168769A3 (en) * 1984-07-16 1989-02-08 Merck & Co. Inc. Process for preparing carboxyalkyl dipeptides
JPH01254651A (ja) * 1988-04-04 1989-10-11 Kanegafuchi Chem Ind Co Ltd Ｎ↑２−（１−カルボキシ−３−フエニルプロピル）−ｌ−リジン誘導体及び該化合物を用いるリジノプリルの製造法
SI9200213A (en) * 1992-09-16 1994-03-31 Krka Process for preparing alkyl-l-alanil-l-proline derivates

Also Published As

Publication number Publication date
EP0943621A3 (en) 2001-12-12
HUP9900153A3 (en) 2002-02-28
IT1299341B1 (it) 2000-03-16
US6031112A (en) 2000-02-29
HUP9900153A2 (hu) 1999-11-29
JPH11269196A (ja) 1999-10-05
ITBO980063A0 (it) 1998-02-09
CA2260450A1 (en) 1999-08-09
ITBO980063A1 (it) 1999-08-09
US6166217A (en) 2000-12-26
BR9900439A (pt) 2000-05-09
TR199900247A2 (xx) 2001-02-21
TR199900247A3 (tr) 2001-02-21
EP0943621A2 (en) 1999-09-22
HU9900153D0 (en) 1999-03-29
IL128264A0 (en) 2000-02-17

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