IL127562A0 - Nuclease protection assays - Google Patents
Nuclease protection assaysInfo
- Publication number
- IL127562A0 IL127562A0 IL12756297A IL12756297A IL127562A0 IL 127562 A0 IL127562 A0 IL 127562A0 IL 12756297 A IL12756297 A IL 12756297A IL 12756297 A IL12756297 A IL 12756297A IL 127562 A0 IL127562 A0 IL 127562A0
- Authority
- IL
- Israel
- Prior art keywords
- protection assays
- nuclease protection
- nuclease
- assays
- protection
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/0061—The surface being organic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00614—Delimitation of the attachment areas
- B01J2219/00621—Delimitation of the attachment areas by physical means, e.g. trenches, raised areas
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/00626—Covalent
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/0063—Other, e.g. van der Waals forces, hydrogen bonding
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00632—Introduction of reactive groups to the surface
- B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00639—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
- B01J2219/00641—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium the porous medium being continuous, e.g. porous oxide substrates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/665,104 US5770370A (en) | 1996-06-14 | 1996-06-14 | Nuclease protection assays |
PCT/US1997/009800 WO1997047640A1 (fr) | 1996-06-14 | 1997-06-16 | Dosages avec protection par une nuclease |
Publications (1)
Publication Number | Publication Date |
---|---|
IL127562A0 true IL127562A0 (en) | 1999-10-28 |
Family
ID=24668724
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12756297A IL127562A0 (en) | 1996-06-14 | 1997-06-16 | Nuclease protection assays |
Country Status (7)
Country | Link |
---|---|
US (1) | US5770370A (fr) |
EP (1) | EP0918786A4 (fr) |
JP (1) | JP2000512499A (fr) |
AU (1) | AU735583B2 (fr) |
CA (1) | CA2258745A1 (fr) |
IL (1) | IL127562A0 (fr) |
WO (1) | WO1997047640A1 (fr) |
Families Citing this family (67)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998029736A1 (fr) * | 1996-12-31 | 1998-07-09 | Genometrix Incorporated | Procede et dispositif d'analyse moleculaire multiplexee |
US6232066B1 (en) * | 1997-12-19 | 2001-05-15 | Neogen, Inc. | High throughput assay system |
US20030096232A1 (en) * | 1997-12-19 | 2003-05-22 | Kris Richard M. | High throughput assay system |
AU2007231625B2 (en) * | 1997-12-19 | 2011-04-07 | Stephen Felder | High Throughput Assay System |
US6238869B1 (en) * | 1997-12-19 | 2001-05-29 | High Throughput Genomics, Inc. | High throughput assay system |
US20030039967A1 (en) * | 1997-12-19 | 2003-02-27 | Kris Richard M. | High throughput assay system using mass spectrometry |
US6458533B1 (en) | 1997-12-19 | 2002-10-01 | High Throughput Genomics, Inc. | High throughput assay system for monitoring ESTs |
US20100105572A1 (en) * | 1997-12-19 | 2010-04-29 | Kris Richard M | High throughput assay system |
WO2000037684A1 (fr) * | 1998-12-22 | 2000-06-29 | Kris Richard M | Systeme d'analyse a haut rendement mettant en oeuvre la spectrometrie de masse |
JP2002517981A (ja) * | 1998-01-13 | 2002-06-25 | ビオヒプ テヒノロギース ゲゼルシャフト ミット ベシュレンクテル ハフツング | 核酸配列を検出するための方法 |
DE19824900B4 (de) * | 1998-06-04 | 2006-05-04 | Roche Diagnostics Gmbh | DNA-Nachweis über einen Strangreassoziationskomplex |
US6908770B1 (en) | 1998-07-16 | 2005-06-21 | Board Of Regents, The University Of Texas System | Fluid based analysis of multiple analytes by a sensor array |
US6326149B1 (en) * | 1998-11-03 | 2001-12-04 | Sarnoff Corporation | Method for controlled electrostatic adherent deposition of particles on a substrate |
US20030092012A1 (en) * | 2001-11-09 | 2003-05-15 | Ahmed Chenna | Methods for detecting a plurality of analytes by chromatography |
ATE346287T1 (de) * | 1999-07-16 | 2006-12-15 | Univ Texas | Verfahren und vorrichtung zur zuführung von proben zu einer chemischen sensormatrix |
EP1218545B1 (fr) | 1999-08-18 | 2012-01-25 | Illumina, Inc. | Procedes de preparation de solutions d'oligonucleotides |
WO2001055704A1 (fr) * | 2000-01-31 | 2001-08-02 | Board Of Regents, The University Of Texas System | Systeme de transfert d'echantillons de fluides a travers un ensemble de capteurs |
FR2805826B1 (fr) * | 2000-03-01 | 2002-09-20 | Nucleica | Nouvelles puces a adn |
EP1387894A4 (fr) * | 2000-08-24 | 2006-10-11 | Aviva Biosciences Corp | Procedes et compositions d'identification de molecules d'acide nucleique au moyen d'activites nucleolytiques et d'hybridation |
US6900013B1 (en) | 2000-08-25 | 2005-05-31 | Aviva Biosciences Corporation | Methods and compositions for identifying nucleic acid molecules using nucleolytic activities and hybridization |
US20040185464A1 (en) * | 2000-09-15 | 2004-09-23 | Kris Richard M. | High throughput assay system |
WO2002040998A2 (fr) * | 2000-11-17 | 2002-05-23 | Zeptosens Ag | Kit et procede permettant la detection d'analytes multiples avec des mesures permettant la referenciation de la densite d'elements de reconnaissance immobilises |
US7022514B2 (en) * | 2000-12-01 | 2006-04-04 | Auburn University | Use of Acacia Gum to isolate and preserve biological material |
US7604807B2 (en) * | 2000-12-01 | 2009-10-20 | Auburn University | Use of pullulan to isolate and preserve biological material |
US20020160363A1 (en) * | 2001-01-31 | 2002-10-31 | Mcdevitt John T. | Magnetic-based placement and retention of sensor elements in a sensor array |
WO2002061392A2 (fr) * | 2001-01-31 | 2002-08-08 | Board Of Regents, The University Of Texas System | Procede et appareil de confinement de materiaux dans un reseau de capteurs chimiques microusines |
AU2002255515A1 (en) * | 2001-02-05 | 2002-08-19 | Board Of Regents, The University Of Texas System | The use of mesoscale self-assembly and recognition to effect delivery of sensing reagent for arrayed sensors |
DE10109779A1 (de) * | 2001-03-01 | 2002-09-19 | Infineon Technologies Ag | Vorrichtung und Verfahren zum Erfassen von makromolekularen Biopolymeren mittels mindestens einer Einheit zum Immobilisieren von makromolekularen Biopolymeren |
KR100436554B1 (ko) * | 2001-04-17 | 2004-06-18 | 삼성전자주식회사 | 혼성화된 핵산의 검출감도를 증가시키는 방법 |
US20050032060A1 (en) * | 2001-08-31 | 2005-02-10 | Shishir Shah | Arrays comprising pre-labeled biological molecules and methods for making and using these arrays |
KR20030049802A (ko) * | 2001-12-17 | 2003-06-25 | 권윤정 | 바이오 칩에서 프로브와 시료 핵산의 혼성화 여부를 효소반응으로 구별하는 방법 |
GB0205455D0 (en) * | 2002-03-07 | 2002-04-24 | Molecular Sensing Plc | Nucleic acid probes, their synthesis and use |
EP1502097A2 (fr) | 2002-04-26 | 2005-02-02 | Board of Regents, The University of Texas System | Methode et systeme permettant de detecter des facteurs de risque cardiaque |
EP1546367A4 (fr) * | 2002-07-24 | 2006-08-16 | Univ Texas | Capture et detection de microbes au moyen de methodes membranaires |
US20040018495A1 (en) * | 2002-07-24 | 2004-01-29 | Xing-Xiang Li | Microparticle based signal amplification for the detection of analytes |
WO2004011606A2 (fr) * | 2002-07-26 | 2004-02-05 | Alfa Wasserman, Inc. | Dosage de protection macromoleculaire |
US20050064452A1 (en) * | 2003-04-25 | 2005-03-24 | Schmid Matthew J. | System and method for the detection of analytes |
US7651850B2 (en) * | 2003-05-16 | 2010-01-26 | Board Of Regents, The University Of Texas System | Image and part recognition technology |
US9317922B2 (en) | 2003-05-16 | 2016-04-19 | Board Of Regents The University Of Texas System | Image and part recognition technology |
US20040265883A1 (en) * | 2003-06-27 | 2004-12-30 | Biocept, Inc. | mRNA expression analysis |
JP4342890B2 (ja) * | 2003-09-30 | 2009-10-14 | 富士フイルム株式会社 | ミスマッチ結合ポリヌクレオチドの除去方法 |
AU2004300168A1 (en) * | 2003-12-11 | 2005-06-30 | Board Of Regents, The University Of Texas System | Method and system for the analysis of saliva using a sensor array |
US20060257991A1 (en) * | 2004-02-27 | 2006-11-16 | Mcdevitt John T | Integration of fluids and reagents into self-contained cartridges containing particle-based sensor elements and membrane-based sensor elements |
US8101431B2 (en) | 2004-02-27 | 2012-01-24 | Board Of Regents, The University Of Texas System | Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems |
US7781226B2 (en) * | 2004-02-27 | 2010-08-24 | The Board Of Regents Of The University Of Texas System | Particle on membrane assay system |
US20060257854A1 (en) * | 2004-02-27 | 2006-11-16 | Mcdevitt John T | Membrane assay system including preloaded particles |
US8105849B2 (en) | 2004-02-27 | 2012-01-31 | Board Of Regents, The University Of Texas System | Integration of fluids and reagents into self-contained cartridges containing sensor elements |
US20060257941A1 (en) * | 2004-02-27 | 2006-11-16 | Mcdevitt John T | Integration of fluids and reagents into self-contained cartridges containing particle and membrane sensor elements |
ATE465276T1 (de) | 2004-03-24 | 2010-05-15 | Achillion Pharmaceuticals Inc | Quantitativer test zum nachweis neu synthetisierter rna in einem zellfreien system sowie identifizierung von inhibitoren der rna- synthese |
JP2005283304A (ja) * | 2004-03-29 | 2005-10-13 | Lintec Corp | プローブアレイ |
US20060008823A1 (en) * | 2004-05-12 | 2006-01-12 | Kemp Jennifer T | DNA profiling and SNP detection utilizing microarrays |
WO2007053186A2 (fr) | 2005-05-31 | 2007-05-10 | Labnow, Inc. | Méthodes et compositions en rapport avec la détermination et l’utilisation de la numération de globules blancs |
EP1899450A4 (fr) * | 2005-06-24 | 2010-03-24 | Univ Texas | Systemes et procedes faisant appel a des cartouches autonomes comprenant des systemes de detection et des systemes de distribution de fluides |
US20080076121A1 (en) * | 2006-09-22 | 2008-03-27 | Paul Kenneth Wolber | Microarray nuclease protection assay |
ES2445892T3 (es) * | 2008-08-25 | 2014-03-05 | Janssen Biotech, Inc. | Biomarcadores para el tratamiento anti-TNF en colitis ulcerosa y trastornos relacionados |
RU2476597C2 (ru) * | 2009-06-16 | 2013-02-27 | Федеральное государственное бюджетное учреждение науки Институт биологии гена Российской академии наук (ИБГ РАН) | Способ идентификации элементов, обладающих способностью терминировать транскрипты |
US8236574B2 (en) * | 2010-03-01 | 2012-08-07 | Quanterix Corporation | Ultra-sensitive detection of molecules or particles using beads or other capture objects |
US10308980B2 (en) | 2011-11-04 | 2019-06-04 | Oslo Universitetssykehus Hf | Methods and biomarkers for analysis of colorectal cancer |
US9822417B2 (en) | 2012-01-09 | 2017-11-21 | Oslo Universitetssykehus Hf | Methods and biomarkers for analysis of colorectal cancer |
CN104220876A (zh) | 2012-02-21 | 2014-12-17 | 奥斯陆大学医院 | 用于宫颈癌的检测和预后的方法和生物标志物 |
US20150111758A1 (en) | 2012-03-06 | 2015-04-23 | Oslo Universitetssykehus Hf | Gene signatures associated with efficacy of postmastectomy radiotherapy in breast cancer |
US9315807B1 (en) | 2013-01-26 | 2016-04-19 | New England Biolabs, Inc. | Genome selection and conversion method |
US9708658B2 (en) | 2013-03-19 | 2017-07-18 | New England Biolabs, Inc. | Enrichment of target sequences |
US10087481B2 (en) | 2013-03-19 | 2018-10-02 | New England Biolabs, Inc. | Enrichment of target sequences |
WO2018127786A1 (fr) | 2017-01-06 | 2018-07-12 | Oslo Universitetssykehus Hf | Compositions et méthodes permettant de déterminer un plan d'action thérapeutique |
CA3063364A1 (fr) * | 2017-01-26 | 2018-08-02 | Qiagen Gmbh | Procede pour l'enrichissement d'acides nucleiques matriciels |
WO2023021330A1 (fr) | 2021-08-16 | 2023-02-23 | University Of Oslo | Compositions et méthodes permettant de déterminer un plan d'action thérapeutique |
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Publication number | Priority date | Publication date | Assignee | Title |
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US4876187A (en) * | 1985-12-05 | 1989-10-24 | Meiogenics, Inc. | Nucleic acid compositions with scissile linkage useful for detecting nucleic acid sequences |
US4946773A (en) * | 1985-12-23 | 1990-08-07 | President And Fellows Of Harvard College | Detection of base pair mismatches using RNAase A |
US5525464A (en) * | 1987-04-01 | 1996-06-11 | Hyseq, Inc. | Method of sequencing by hybridization of oligonucleotide probes |
GB8810400D0 (en) * | 1988-05-03 | 1988-06-08 | Southern E | Analysing polynucleotide sequences |
US5424186A (en) * | 1989-06-07 | 1995-06-13 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis |
US5143854A (en) * | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
US5380662A (en) * | 1990-06-01 | 1995-01-10 | Robbins Scientific Corporation | Hybridization incubator with rotisserie mechanism |
EP0562025B1 (fr) * | 1990-12-06 | 2001-02-07 | Affymetrix, Inc. (a Delaware Corporation) | Substances et leur utilisation pour un strategie binaire de la synthése |
ES2097925T3 (es) * | 1991-09-18 | 1997-04-16 | Affymax Tech Nv | Metodo para sintetizar diversas colecciones de oligomeros. |
US5359115A (en) * | 1992-03-26 | 1994-10-25 | Affymax Technologies, N.V. | Methods for the synthesis of phosphonate esters |
AU3919293A (en) * | 1992-03-27 | 1993-11-08 | University Of Maryland At Baltimore | Detection of gene mutations with mismatch repair enzymes |
US5420328A (en) * | 1992-09-11 | 1995-05-30 | Affymax Technologies, N.V. | Methods for the synthesis of phosphonate esters |
SE9500341D0 (sv) * | 1995-01-30 | 1995-01-30 | Ulf Landegren | Method for detecting DNA sequence variations |
EP0843736B1 (fr) * | 1995-05-11 | 1999-12-22 | Ulf Landegren | Detection d'erreurs d'appariement par clivage de resolvase sur un support solide |
US5753439A (en) * | 1995-05-19 | 1998-05-19 | Trustees Of Boston University | Nucleic acid detection methods |
-
1996
- 1996-06-14 US US08/665,104 patent/US5770370A/en not_active Expired - Lifetime
-
1997
- 1997-06-16 JP JP10501695A patent/JP2000512499A/ja active Pending
- 1997-06-16 EP EP97927995A patent/EP0918786A4/fr not_active Withdrawn
- 1997-06-16 AU AU32320/97A patent/AU735583B2/en not_active Ceased
- 1997-06-16 WO PCT/US1997/009800 patent/WO1997047640A1/fr not_active Application Discontinuation
- 1997-06-16 IL IL12756297A patent/IL127562A0/xx unknown
- 1997-06-16 CA CA002258745A patent/CA2258745A1/fr not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US5770370A (en) | 1998-06-23 |
AU3232097A (en) | 1998-01-07 |
EP0918786A4 (fr) | 2002-03-20 |
CA2258745A1 (fr) | 1997-12-18 |
EP0918786A1 (fr) | 1999-06-02 |
JP2000512499A (ja) | 2000-09-26 |
AU735583B2 (en) | 2001-07-12 |
WO1997047640A1 (fr) | 1997-12-18 |
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