IL126843A - Mhc class ii antigen-presenting systems and methods for activating cd4+t cells in vitro - Google Patents
Mhc class ii antigen-presenting systems and methods for activating cd4+t cells in vitroInfo
- Publication number
- IL126843A IL126843A IL126843A IL12684397A IL126843A IL 126843 A IL126843 A IL 126843A IL 126843 A IL126843 A IL 126843A IL 12684397 A IL12684397 A IL 12684397A IL 126843 A IL126843 A IL 126843A
- Authority
- IL
- Israel
- Prior art keywords
- molecule
- matrix
- cells
- mhc class
- accessory
- Prior art date
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Landscapes
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1817596P | 1996-05-23 | 1996-05-23 | |
| PCT/US1997/008697 WO1997046256A1 (en) | 1996-05-23 | 1997-05-22 | Mhc class ii antigen-presenting systems and methods for activating cd4+ t cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL126843A0 IL126843A0 (en) | 1999-09-22 |
| IL126843A true IL126843A (en) | 2007-06-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL126843A IL126843A (en) | 1996-05-23 | 1997-05-22 | Mhc class ii antigen-presenting systems and methods for activating cd4+t cells in vitro |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US6355479B1 (https=) |
| EP (1) | EP0969865B1 (https=) |
| JP (2) | JP5006998B2 (https=) |
| AT (1) | ATE347588T1 (https=) |
| AU (1) | AU723355B2 (https=) |
| CA (1) | CA2254975C (https=) |
| DE (1) | DE69737070T2 (https=) |
| DK (1) | DK0969865T3 (https=) |
| ES (1) | ES2278390T3 (https=) |
| IL (1) | IL126843A (https=) |
| PT (1) | PT969865E (https=) |
| WO (1) | WO1997046256A1 (https=) |
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| US10857219B2 (en) | 2014-03-28 | 2020-12-08 | The Board Of Regents Of The University Of Oklahoma | Compositions comprising soluble HLA/M. tuberculosis-specific ligand complexes and methods of production and use thereof |
| CA2945388A1 (en) | 2014-04-23 | 2015-10-29 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors (car) for use in therapy and methods for making the same |
| KR20200138445A (ko) | 2014-04-24 | 2020-12-09 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 입양 세포 요법 생성물을 생성하기 위한 유도 만능 줄기 세포의 응용 |
| US20170333480A1 (en) | 2014-11-05 | 2017-11-23 | Board Of Regents, The University Of Texas System | Gene modified immune effector cells and engineered cells for expansion of immune effector cells |
| CA2964783C (en) | 2014-11-05 | 2024-01-23 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors (car) to selectively target protein complexes |
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| EP3368075B1 (en) | 2015-10-27 | 2020-01-29 | Board of Regents, The University of Texas System | Chimeric antigen receptor molecules and uses thereof |
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| US11285196B2 (en) | 2017-03-13 | 2022-03-29 | Eslam Abbas Baseuny | Multivalent biologic constructs for inducing a therapeutic modulation of cellular response and uses thereof |
| SG11201909331UA (en) | 2017-04-18 | 2019-11-28 | Fujifilm Cellular Dynamics Inc | Antigen-specific immune effector cells |
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| JP2021500878A (ja) | 2017-10-12 | 2021-01-14 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 免疫療法のためのｔ細胞受容体 |
| US12473336B2 (en) | 2018-02-21 | 2025-11-18 | Board Of Regents, The University Of Texas System | Methods for activation and expansion of natural killer cells and uses thereof |
| MX2021006208A (es) | 2018-11-28 | 2021-10-01 | Univ Texas | Edición por multiplexación del genoma de células inmunitarias para mejorar la funcionalidad y resistencia al entorno supresor. |
| MX2021006393A (es) | 2018-11-29 | 2021-10-13 | Univ Texas | Metodos para expansion ex vivo de celulas exterminadoras naturales y uso de las mismas. |
| US20220387493A1 (en) | 2019-11-06 | 2022-12-08 | Baylor College Of Medicine | Method for producing cytotoxic effector memory t-cells for car t-cell treatment of cancer |
| US20230079539A1 (en) | 2020-02-10 | 2023-03-16 | Board Of Regents, The University Of Texas System | Methods for rapid cloning and expression of hla class i cells |
| CN115715295A (zh) | 2020-05-27 | 2023-02-24 | 安逊生物科学股份有限公司 | 将car t细胞重新定向到感兴趣的抗原的衔接分子 |
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| EP4514382A1 (en) | 2022-04-28 | 2025-03-05 | Musc Foundation for Research Development | Chimeric antigen receptor modified regulatory t cells for treating cancer |
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| US5242687A (en) * | 1989-03-15 | 1993-09-07 | Tkb Associates Limited Partnership | Method of reducing cellular immune response involving T-cells using CD8-bearing antigen presenting cells |
| US5395760A (en) | 1989-09-05 | 1995-03-07 | Immunex Corporation | DNA encoding tumor necrosis factor-α and -β receptors |
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| US5583031A (en) * | 1992-02-06 | 1996-12-10 | President And Fellows Of Harvard College | Empty major histocompatibility class II heterodimers |
| US5314813A (en) * | 1992-02-19 | 1994-05-24 | Scripps Research Institute | Drosophila cell lines expressing genes encoding MHC class I antigens and B2-microglobulin and capable of assembling empty complexes and methods of making said cell lines |
| WO1996012009A2 (en) * | 1994-10-14 | 1996-04-25 | Tykocinski Mark L | Methods for engineering antigen-presenting cells |
| ES2278390T3 (es) * | 1996-05-23 | 2007-08-01 | The Scripps Research Institute | Sistema de presentacion de antigenos de clase ii de cmh y procedimientos de activacion de linfocitos t cd4+. |
-
1997
- 1997-05-22 ES ES97927709T patent/ES2278390T3/es not_active Expired - Lifetime
- 1997-05-22 AT AT97927709T patent/ATE347588T1/de active
- 1997-05-22 EP EP97927709A patent/EP0969865B1/en not_active Expired - Lifetime
- 1997-05-22 PT PT97927709T patent/PT969865E/pt unknown
- 1997-05-22 AU AU32103/97A patent/AU723355B2/en not_active Expired
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- 1997-05-22 WO PCT/US1997/008697 patent/WO1997046256A1/en not_active Ceased
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| US7402430B2 (en) | 2008-07-22 |
| US20050059144A1 (en) | 2005-03-17 |
| AU723355B2 (en) | 2000-08-24 |
| EP0969865A1 (en) | 2000-01-12 |
| CA2254975A1 (en) | 1997-12-11 |
| ATE347588T1 (de) | 2006-12-15 |
| EP0969865A4 (en) | 2001-07-11 |
| US7074617B1 (en) | 2006-07-11 |
| DE69737070T2 (de) | 2007-06-21 |
| JP5006998B2 (ja) | 2012-08-22 |
| AU3210397A (en) | 1998-01-05 |
| EP0969865B1 (en) | 2006-12-06 |
| DK0969865T3 (da) | 2007-03-19 |
| ES2278390T3 (es) | 2007-08-01 |
| JP2000511898A (ja) | 2000-09-12 |
| PT969865E (pt) | 2007-02-28 |
| DE69737070D1 (de) | 2007-01-18 |
| US6355479B1 (en) | 2002-03-12 |
| IL126843A0 (en) | 1999-09-22 |
| JP2012143245A (ja) | 2012-08-02 |
| US20050054090A1 (en) | 2005-03-10 |
| US7439335B2 (en) | 2008-10-21 |
| WO1997046256A1 (en) | 1997-12-11 |
| CA2254975C (en) | 2008-12-16 |
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