IL125381A0 - Hydroxamic acid based collagenase inhibitors - Google Patents
Hydroxamic acid based collagenase inhibitorsInfo
- Publication number
- IL125381A0 IL125381A0 IL12538197A IL12538197A IL125381A0 IL 125381 A0 IL125381 A0 IL 125381A0 IL 12538197 A IL12538197 A IL 12538197A IL 12538197 A IL12538197 A IL 12538197A IL 125381 A0 IL125381 A0 IL 125381A0
- Authority
- IL
- Israel
- Prior art keywords
- hydroxamic acid
- acid based
- collagenase inhibitors
- based collagenase
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9601041.8A GB9601041D0 (en) | 1996-01-17 | 1996-01-17 | Novel compounds |
| PCT/EP1997/000196 WO1997026257A1 (en) | 1996-01-17 | 1997-01-14 | Hydroxamic acid based collagenase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL125381A0 true IL125381A0 (en) | 1999-03-12 |
Family
ID=10787226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12538197A IL125381A0 (en) | 1996-01-17 | 1997-01-14 | Hydroxamic acid based collagenase inhibitors |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0912545A1 (cs) |
| JP (1) | JP2000503312A (cs) |
| KR (1) | KR19990077325A (cs) |
| CN (1) | CN1213368A (cs) |
| AR (1) | AR005472A1 (cs) |
| AU (1) | AU725056B2 (cs) |
| BR (1) | BR9707024A (cs) |
| CA (1) | CA2242913A1 (cs) |
| CZ (1) | CZ222498A3 (cs) |
| GB (1) | GB9601041D0 (cs) |
| HU (1) | HUP9901022A3 (cs) |
| IL (1) | IL125381A0 (cs) |
| NO (1) | NO983283L (cs) |
| NZ (1) | NZ326352A (cs) |
| PL (1) | PL327820A1 (cs) |
| TR (1) | TR199801380T2 (cs) |
| TW (1) | TW462967B (cs) |
| WO (1) | WO1997026257A1 (cs) |
| ZA (1) | ZA97345B (cs) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6548084B2 (en) | 1995-07-20 | 2003-04-15 | Smithkline Beecham Plc | Controlled release compositions |
| GB9609795D0 (en) * | 1996-05-10 | 1996-07-17 | Smithkline Beecham Plc | Novel compounds |
| WO2000040713A1 (en) * | 1999-01-06 | 2000-07-13 | Mcmaster University | Method of preventing immune and hypersensitivity reactions |
| GB9922825D0 (en) * | 1999-09-25 | 1999-11-24 | Smithkline Beecham Biolog | Medical use |
| AU2001271068A1 (en) * | 2000-07-18 | 2002-01-30 | Chugai Seiyaku Kabushiki Kaisha | Matrix metalloprotease inhibitors |
| JP2005532261A (ja) * | 2002-01-28 | 2005-10-27 | エイムスコ・リミテッド | 治療 |
| JPWO2006016399A1 (ja) | 2004-08-10 | 2008-05-01 | 株式会社静岡カフェイン工業所 | ヒドロキサム酸誘導体及びそれを有効成分とする医薬 |
| KR100844277B1 (ko) * | 2005-04-29 | 2008-07-07 | (주)아모레퍼시픽 | 히드록삼산 유도체 및 이의 제조방법 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4743587A (en) * | 1985-09-10 | 1988-05-10 | G. D. Searle & Co. | Hydroxamic acid based collagenase inhibitors |
| GB8827305D0 (en) * | 1988-11-23 | 1988-12-29 | British Bio Technology | Compounds |
| GB9504084D0 (en) * | 1995-03-01 | 1995-04-19 | British Biotech Pharm | Synthesis of carboxylic and hydroxamic acid derivatives |
-
1996
- 1996-01-17 GB GBGB9601041.8A patent/GB9601041D0/en active Pending
-
1997
- 1997-01-14 WO PCT/EP1997/000196 patent/WO1997026257A1/en not_active Application Discontinuation
- 1997-01-14 KR KR1019980705472A patent/KR19990077325A/ko not_active Application Discontinuation
- 1997-01-14 NZ NZ326352A patent/NZ326352A/xx unknown
- 1997-01-14 CZ CZ982224A patent/CZ222498A3/cs unknown
- 1997-01-14 EP EP97901055A patent/EP0912545A1/en not_active Withdrawn
- 1997-01-14 PL PL97327820A patent/PL327820A1/xx unknown
- 1997-01-14 IL IL12538197A patent/IL125381A0/xx unknown
- 1997-01-14 CA CA002242913A patent/CA2242913A1/en not_active Abandoned
- 1997-01-14 HU HU9901022A patent/HUP9901022A3/hu unknown
- 1997-01-14 BR BR9707024A patent/BR9707024A/pt unknown
- 1997-01-14 AU AU14436/97A patent/AU725056B2/en not_active Ceased
- 1997-01-14 TR TR1998/01380T patent/TR199801380T2/xx unknown
- 1997-01-14 CN CN97192982A patent/CN1213368A/zh active Pending
- 1997-01-14 JP JP9525693A patent/JP2000503312A/ja active Pending
- 1997-01-15 AR ARP970100153A patent/AR005472A1/es unknown
- 1997-01-16 ZA ZA97345A patent/ZA97345B/xx unknown
- 1997-01-30 TW TW086101017A patent/TW462967B/zh active
-
1998
- 1998-07-16 NO NO983283A patent/NO983283L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA97345B (en) | 1998-07-16 |
| HUP9901022A2 (hu) | 1999-07-28 |
| JP2000503312A (ja) | 2000-03-21 |
| CZ222498A3 (cs) | 1999-03-17 |
| NO983283D0 (no) | 1998-07-16 |
| PL327820A1 (en) | 1999-01-04 |
| GB9601041D0 (en) | 1996-03-20 |
| AR005472A1 (es) | 1999-06-23 |
| KR19990077325A (ko) | 1999-10-25 |
| WO1997026257A1 (en) | 1997-07-24 |
| AU1443697A (en) | 1997-08-11 |
| TR199801380T2 (xx) | 1998-10-21 |
| NO983283L (no) | 1998-09-16 |
| CA2242913A1 (en) | 1997-07-24 |
| HUP9901022A3 (en) | 2001-11-28 |
| BR9707024A (pt) | 1999-07-20 |
| NZ326352A (en) | 2000-03-27 |
| CN1213368A (zh) | 1999-04-07 |
| AU725056B2 (en) | 2000-10-05 |
| EP0912545A1 (en) | 1999-05-06 |
| TW462967B (en) | 2001-11-11 |
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