IL123563A - Pharmaceutical formulations comprising amoxycillin and clavulanate in a weight ratio between 14:1 and 16:1 inclusive - Google Patents

Pharmaceutical formulations comprising amoxycillin and clavulanate in a weight ratio between 14:1 and 16:1 inclusive

Info

Publication number
IL123563A
IL123563A IL12356396A IL12356396A IL123563A IL 123563 A IL123563 A IL 123563A IL 12356396 A IL12356396 A IL 12356396A IL 12356396 A IL12356396 A IL 12356396A IL 123563 A IL123563 A IL 123563A
Authority
IL
Israel
Prior art keywords
amoxycillin
clavulanate
formulation
ratio
inclusive
Prior art date
Application number
IL12356396A
Other languages
English (en)
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21705455&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL123563(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of IL123563A publication Critical patent/IL123563A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
IL12356396A 1995-09-07 1996-09-05 Pharmaceutical formulations comprising amoxycillin and clavulanate in a weight ratio between 14:1 and 16:1 inclusive IL123563A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US335395P 1995-09-07 1995-09-07
PCT/US1996/014554 WO1997009042A1 (fr) 1995-09-07 1996-09-05 Preparation pharmaceutique

Publications (1)

Publication Number Publication Date
IL123563A true IL123563A (en) 2002-02-10

Family

ID=21705455

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12356396A IL123563A (en) 1995-09-07 1996-09-05 Pharmaceutical formulations comprising amoxycillin and clavulanate in a weight ratio between 14:1 and 16:1 inclusive

Country Status (28)

Country Link
US (3) US6726908B2 (fr)
EP (3) EP0862431B1 (fr)
JP (1) JP3501289B2 (fr)
KR (1) KR100495585B1 (fr)
CN (1) CN1289084C (fr)
AR (1) AR004510A1 (fr)
AT (1) ATE208618T1 (fr)
AU (1) AU711441B2 (fr)
BR (1) BR9610396A (fr)
CA (1) CA2231194C (fr)
CO (1) CO4750658A1 (fr)
CY (1) CY2359B1 (fr)
CZ (1) CZ299595B6 (fr)
DE (1) DE69617036T2 (fr)
DK (1) DK0862431T3 (fr)
ES (1) ES2165997T3 (fr)
HK (2) HK1043042A1 (fr)
HU (1) HUP9901437A3 (fr)
IL (1) IL123563A (fr)
NO (1) NO314831B1 (fr)
NZ (3) NZ337247A (fr)
PL (1) PL325411A1 (fr)
PT (1) PT862431E (fr)
SI (1) SI0862431T1 (fr)
TR (1) TR199800415T1 (fr)
TW (1) TW501926B (fr)
WO (1) WO1997009042A1 (fr)
ZA (1) ZA967546B (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030109503A1 (en) * 1995-06-06 2003-06-12 Smithkline Beecham P.L.C. Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics
JP3501289B2 (ja) * 1995-09-07 2004-03-02 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 医薬処方
GB9617780D0 (en) * 1996-08-24 1996-10-02 Smithkline Beecham Plc Method of treatment
US7250176B1 (en) * 1999-04-13 2007-07-31 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection
GB2365337A (en) * 1999-04-13 2002-02-20 Beecham Pharma Amoxycillin and potassium clavulanate high dosage regimen
ITMI20000788A1 (it) * 1999-04-13 2001-10-11 Beecham Pharmaceuticals Pte Li Nuovo metodo di trattamento
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
US6294199B1 (en) 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
WO2001000177A1 (fr) * 1999-06-29 2001-01-04 Micio Pharma Chemical Aktiengesellschaft Formulation retard d'amoxicilline administree par voie orale
US6955821B2 (en) 2000-04-28 2005-10-18 Adams Laboratories, Inc. Sustained release formulations of guaifenesin and additional drug ingredients
US7985420B2 (en) 2000-04-28 2011-07-26 Reckitt Benckiser Inc. Sustained release of guaifenesin combination drugs
US7838032B2 (en) 2000-04-28 2010-11-23 Reckitt Benckiser Inc. Sustained release of guaifenesin
US8012504B2 (en) 2000-04-28 2011-09-06 Reckitt Benckiser Inc. Sustained release of guaifenesin combination drugs
US6756057B2 (en) 2000-10-12 2004-06-29 Beecham Pharmaceuticals (Pte) Limited Amoxicillin and potassium clavulanate dosage form
AU2001292185A1 (en) 2000-10-12 2002-04-22 Beecham Pharmaceuticals (Pte) Limited Formulation containing amoxicillin
DE60325709D1 (de) 2002-04-09 2009-02-26 Flamel Tech Sa Orale wässrige suspension, mikrokapseln enthaltend, zur kontrollierten freisetzung von wirkstoffen
KR100456833B1 (ko) * 2002-08-01 2004-11-10 주식회사 대웅 아목시실린 및 클라불라네이트를 함유하는 유핵정
US8614315B2 (en) 2009-12-25 2013-12-24 Mahmut Bilgic Cefdinir and cefixime formulations and uses thereof
TR200909787A2 (tr) 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Üçüncü kuşak bir sefalosporin ve klavulanik asit içeren farmasötik formülasyonlar.
TR201000686A1 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@
TR201000688A2 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Aktif madde olarak sefaklor ve klavulanik asit içeren efervesan formülasyonlar.
TR201000687A1 (tr) 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Aktif madde olarak sefiksim ve klavulanik asit içeren efervesan formülasyonlar
WO2013057569A2 (fr) 2011-10-19 2013-04-25 Micro Labs Limited Composition pharmaceutique à libération prolongée contenant de l'amoxicilline et de l'acide clavulanique
EP2802327A1 (fr) * 2012-01-10 2014-11-19 Michael Spector Formulations de suspension orale pédiatrique d'amoxicilline et de clavulanate de potassium et leur procédé d'utilisation
WO2013173803A2 (fr) * 2012-05-17 2013-11-21 Michael Spector Formulations d'amoxicilline et de clavulanate de potassium et procédés d'utilisation de celles-ci
WO2013173808A2 (fr) * 2012-05-17 2013-11-21 Michael Spector Procédés d'utilisation de compositions à dose plus faible d'amoxicilline et de clavulanate de potassium et dispositifs d'utilisation
CA3001337C (fr) 2015-10-09 2023-12-12 Reckitt Benckiser Llc Formulation pharmaceutique

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE41109B1 (en) * 1974-04-20 1979-10-24 Beecham Group Ltd Novel -lactam antibiotic from streptomyces clavuligerus
JO984B1 (en) * 1977-10-11 1979-12-01 بيتشام غروب ليمتد A dry pharmaceutical compound with a suitable dosage unit for oral administration
IL58461A0 (en) 1978-10-27 1980-01-31 Beecham Group Ltd Intramammary compositions comprising a clavulanic acid salt
NZ198241A (en) * 1980-09-27 1983-12-16 Beecham Group Ltd Tablet containing amoxycillin and potassium clavulanate
DE3266580D1 (en) * 1981-12-02 1985-10-31 Beecham Group Plc Pharmaceutical formulation comprising beta-lactam antibiotics
US4673637A (en) 1984-04-23 1987-06-16 Hyman Edward S Method for detecting bacteria in urine and for treating rheumatoid arthritis, essential hypertension and other diseases associated with bacteriuria
ES2061623T3 (es) 1987-03-02 1994-12-16 Brocades Pharma Bv Procedimiento para la obtencion de una composicion farmaceutica y un granulado farmaceutico.
US5114929A (en) * 1989-03-21 1992-05-19 Beecham Group P.L.C. Pharmaceutical formulation
GB8909793D0 (en) 1989-04-28 1989-06-14 Beecham Group Plc Pharmaceutical formulation
KR910009271B1 (ko) 1989-06-20 1991-11-08 김영설 1,1-디옥소페닐실라노일 옥시메틸 D-6-[α-(메틸렌아미노)페닐-아세트아미도]-페니실라네이트와 그의 파라-톨루엔술폰산염
GB9007945D0 (en) * 1990-04-07 1990-06-06 Beecham Group Plc Pharmaceutical formulation
US5814337A (en) 1992-10-07 1998-09-29 Beecham Group Plc Pharmaceutical formulation
GB9109862D0 (en) 1991-05-08 1991-07-03 Beecham Lab Sa Pharmaceutical formulations
GB9114950D0 (en) 1991-07-11 1991-08-28 Smithkline Beecham Plc Pharmaceutical formulation
WO1994016696A1 (fr) * 1993-01-22 1994-08-04 Smithkline Beecham Plc Formulations pharmaceutiques comprenant de l'acide clavulanique seul ou associe a d'autres beta-lactamines
GB9311030D0 (en) 1993-05-28 1993-07-14 Smithkline Beecham Corp Pharmaceutical formulations
IL109770A0 (en) * 1993-05-29 1994-11-28 Smithkline Beecham Corp Thermal infusion process for preparing controlled release solid dosage forms of medicaments for oral administration and controlled release solid dosage forms of medicaments prepared thereby
GB9405856D0 (en) 1994-03-24 1994-05-11 Smithkline Beecham Plc Pharmaceutical formulation
GB9407386D0 (en) 1994-04-14 1994-06-08 Smithkline Beecham Plc Pharmaceutical formulation
GB9408117D0 (en) 1994-04-23 1994-06-15 Smithkline Beecham Corp Pharmaceutical formulations
ITMI941169A1 (it) 1994-06-06 1995-12-06 Smithkline Beecham Farma Formulazioni farmaceutiche
US5567439A (en) 1994-06-14 1996-10-22 Fuisz Technologies Ltd. Delivery of controlled-release systems(s)
GB9416600D0 (en) 1994-08-17 1994-10-12 Smithkline Beecham Plc Pharmaceutical formulation
GB9416599D0 (en) 1994-08-17 1994-10-12 Smithkline Beecham Plc Pharmaceutical formulation
DZ1926A1 (fr) 1994-09-03 2002-02-17 Smithkline Beckman P L C Formulations pharmaceutiques.
DZ2028A1 (fr) 1995-05-03 2002-10-23 Smithkline Beecham Plc Médicaments destinés au traitement d'infections bactériennes en pédiatrie.
US5830073A (en) 1995-07-28 1998-11-03 Voss; Brian C. Bowling lane surfaces
JP3501289B2 (ja) * 1995-09-07 2004-03-02 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 医薬処方
ES2201468T3 (es) 1997-02-14 2004-03-16 Laboratoire Glaxosmithkline S.A.S. Preparacion farmaceutica que comprende amoxicilina y clavulanato.
SE9700885D0 (sv) 1997-03-12 1997-03-12 Astra Ab New pharmaceutical formulation
DE69828595T2 (de) 1997-03-25 2006-01-05 Takeda Pharmaceutical Co. Ltd. Gastrointestinale an der mucosa haftende pharmazeutische zusammensetzung
GB9815532D0 (en) 1998-07-17 1998-09-16 Lek Pharmaceutical & Cvhemical Pharmaceutical suspension formulation
GB9818927D0 (en) 1998-08-28 1998-10-21 Smithkline Beecham Plc Pharmaceutical formulation
ITMI20000788A1 (it) * 1999-04-13 2001-10-11 Beecham Pharmaceuticals Pte Li Nuovo metodo di trattamento

Also Published As

Publication number Publication date
NZ318282A (en) 2000-01-28
KR19990044495A (ko) 1999-06-25
WO1997009042A1 (fr) 1997-03-13
HK1015701A1 (en) 1999-10-22
CN1200672A (zh) 1998-12-02
US20010038838A1 (en) 2001-11-08
EP0862431A1 (fr) 1998-09-09
DE69617036T2 (de) 2002-07-11
EP0862431A4 (fr) 1999-07-07
CA2231194C (fr) 2004-07-20
AR004510A1 (es) 1998-12-16
CY2359B1 (en) 2004-06-04
JPH11512398A (ja) 1999-10-26
HK1043042A1 (zh) 2002-09-06
CO4750658A1 (es) 1999-03-31
CZ299595B6 (cs) 2008-09-17
NZ337247A (en) 2001-05-25
ES2165997T3 (es) 2002-04-01
MX9801903A (es) 1998-05-31
NO981008L (no) 1998-05-06
NZ337246A (en) 2000-07-28
PL325411A1 (en) 1998-07-20
NO981008D0 (no) 1998-03-06
JP3501289B2 (ja) 2004-03-02
ATE208618T1 (de) 2001-11-15
CZ68398A3 (cs) 1998-07-15
TW501926B (en) 2002-09-11
ZA967546B (en) 1998-03-06
HUP9901437A3 (en) 2000-03-28
US20010043926A1 (en) 2001-11-22
TR199800415T1 (en) 1998-05-21
EP1093812A2 (fr) 2001-04-25
PT862431E (pt) 2002-04-29
US20050261267A1 (en) 2005-11-24
AU6973396A (en) 1997-03-27
HUP9901437A2 (hu) 1999-09-28
EP1147771A1 (fr) 2001-10-24
EP1093812A3 (fr) 2001-06-06
US6726908B2 (en) 2004-04-27
EP0862431B1 (fr) 2001-11-14
CN1289084C (zh) 2006-12-13
DK0862431T3 (da) 2002-03-11
BR9610396A (pt) 1999-07-06
DE69617036D1 (de) 2001-12-20
AU711441B2 (en) 1999-10-14
NO314831B1 (no) 2003-06-02
SI0862431T1 (en) 2002-06-30
KR100495585B1 (ko) 2005-09-09
CA2231194A1 (fr) 1997-03-13

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