IL123398A0 - Cloning methods for high strength spider silk proteins - Google Patents

Cloning methods for high strength spider silk proteins

Info

Publication number
IL123398A0
IL123398A0 IL12339896A IL12339896A IL123398A0 IL 123398 A0 IL123398 A0 IL 123398A0 IL 12339896 A IL12339896 A IL 12339896A IL 12339896 A IL12339896 A IL 12339896A IL 123398 A0 IL123398 A0 IL 123398A0
Authority
IL
Israel
Prior art keywords
high strength
spider silk
cloning methods
silk proteins
proteins
Prior art date
Application number
IL12339896A
Other languages
English (en)
Inventor
Richard M Basel
Glenn R Elion
Original Assignee
Agricola Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agricola Tech Inc filed Critical Agricola Tech Inc
Publication of IL123398A0 publication Critical patent/IL123398A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Insects & Arthropods (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
IL12339896A 1995-08-22 1996-08-22 Cloning methods for high strength spider silk proteins IL123398A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51769495A 1995-08-22 1995-08-22
PCT/US1996/013767 WO1997008315A1 (en) 1995-08-22 1996-08-22 Cloning methods for high strength spider silk proteins

Publications (1)

Publication Number Publication Date
IL123398A0 true IL123398A0 (en) 1998-09-24

Family

ID=24060849

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12339896A IL123398A0 (en) 1995-08-22 1996-08-22 Cloning methods for high strength spider silk proteins

Country Status (7)

Country Link
EP (1) EP0848754A1 (zh)
JP (1) JPH11511325A (zh)
CN (1) CN1200145A (zh)
AU (1) AU7152996A (zh)
BR (1) BR9612625A (zh)
IL (1) IL123398A0 (zh)
WO (1) WO1997008315A1 (zh)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2774588B1 (fr) * 1998-02-11 2000-05-05 Oreal Composition cosmetique ou dermatologique contenant au moins une proteine de soie d'arachnides naturelle, recombinante ou un analogue
US7157615B2 (en) 1998-03-17 2007-01-02 Nexia Biotechnologies, Inc. Production of biofilaments in transgenic animals
EP1251888A1 (en) * 2000-02-03 2002-10-30 Nexia Biotechnologies, Inc. Surgical sutures containing spider silk
US6608242B1 (en) * 2000-05-25 2003-08-19 E. I. Du Pont De Nemours And Company Production of silk-like proteins in plants
US20060248615A1 (en) * 2000-06-09 2006-11-02 Jurgen Scheller Synthetic spider silk proteins and expression thereof in transgenic plants
US6642361B2 (en) * 2000-06-29 2003-11-04 Fiona F. Hunter Isolated cocoon silk protein from Simulium vittatum and nucleic acids encoding such protein
US20110009960A1 (en) 2001-11-16 2011-01-13 Allergan, Inc. Prosthetic fabric structure
AU2003202330A1 (en) * 2002-01-11 2003-07-24 Nexia Biotechnologies, Inc. Recovery of biofilament proteins from biological fluids
WO2004000915A2 (en) 2002-06-24 2003-12-31 Tufts University Silk biomaterials and methods of use thereof
CA2518509C (en) 2003-03-11 2014-04-29 Tissue Regeneration, Inc. Immunoneutral silk-fiber-based medical devices
EP1613796B1 (en) 2003-04-10 2017-03-22 Tufts University Concentrated aqueous silk fibroin solution and use thereof
CA2624667C (en) * 2005-10-05 2018-01-09 Commonwealth Scientific And Industrial Research Organisation Silk proteins containing coiled coil region
CA2635660C (en) 2005-12-30 2016-02-23 Spiber Technologies Ab Spider silk proteins and methods for producing spider silk proteins
WO2008118133A2 (en) 2006-09-26 2008-10-02 Trustees Of Tufts College Silk microspheres for encapsulation and controlled release
EP2129772B1 (en) 2007-02-27 2016-07-27 Trustees Of Tufts College Tissue-engineered silk organs
WO2009023615A1 (en) 2007-08-10 2009-02-19 Trustees Of Tufts College Tubular silk compositions and methods of use thereof
EP2249886A4 (en) * 2008-02-07 2013-05-22 Tufts College THREE DIMENSIONAL HYDROXYAPATITIS AND SILK COMPOSITIONS
WO2010042798A2 (en) 2008-10-09 2010-04-15 Trustees Of Tufts College Modified silk films containing glycerol
WO2010057142A2 (en) 2008-11-17 2010-05-20 Trustees Of Tufts College Surface modification of silk fibroin matrices with poly(ethylene glycol) useful as anti adhesion barriers and anti thrombotic materials
US9308070B2 (en) 2008-12-15 2016-04-12 Allergan, Inc. Pliable silk medical device
US20130245757A1 (en) 2011-11-04 2013-09-19 Allergan, Inc. Method and device for improved soft tissue surgery
WO2011005381A2 (en) 2009-06-01 2011-01-13 Trustees Of Tufts College Vortex-induced silk fibroin gelation for encapsulation and delivery
US9016875B2 (en) 2009-07-20 2015-04-28 Tufts University/Trustees Of Tufts College All-protein implantable, resorbable reflectors
WO2011031854A1 (en) 2009-09-11 2011-03-17 Allergan, Inc. Prosthetic device and method of manufacturing the same
US9603971B2 (en) 2010-03-05 2017-03-28 Trustees Of Tufts College Silk-based ionomeric compositions
CN103181025A (zh) 2010-04-12 2013-06-26 塔夫茨大学 丝电子部件
JP6053682B2 (ja) 2010-08-30 2016-12-27 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 高強度キチン複合材料および製造方法
CA2847590A1 (en) 2010-09-03 2012-03-08 Tufts University/Trustees Of Tufts College Plasmonic nanoparticle-doped silk materials
JP5691052B2 (ja) * 2010-09-10 2015-04-01 岡本株式会社 組換え生物及び組換え生物により作られるタンパク質
JP2014502416A (ja) 2010-09-27 2014-01-30 タフツ ユニバーシティー/トラスティーズ オブ タフツ カレッジ 絹ベースの圧電性材料
EP4218891A1 (en) 2010-10-19 2023-08-02 Trustees Of Tufts College Silk fibroin-based microneedles and methods of making the same
US10335519B2 (en) 2011-04-20 2019-07-02 Trustees Of Tufts College Dynamic silk coatings for implantable devices
US20140287043A1 (en) 2011-04-21 2014-09-25 Trustees Of Tufts College Compositions and methods for stabilization of active agents
WO2013070907A1 (en) 2011-11-08 2013-05-16 Tufts University A silk-based scaffold platform for engineering tissue constructs
ES2953309T3 (es) 2011-11-09 2023-11-10 Tufts College Partículas de fibroína de seda inyectables y usos de las mismas
KR102176406B1 (ko) 2011-11-09 2020-11-09 트러스티즈 오브 터프츠 칼리지 주사가능한 실크 피브로인 발포체 및 그의 용도
WO2013130156A2 (en) 2011-12-05 2013-09-06 Tufts University Signal enhancement by silk photonic crystals
WO2013102193A1 (en) 2011-12-29 2013-07-04 Trustees Of Tufts College Functionalization of biomaterials to control regeneration and inflammation responses
ES2856873T3 (es) 2012-02-06 2021-09-28 Childrens Medical Center Biomaterial multicapa para la regeneración de tejidos y la cicatrización de las heridas
NL1039495C2 (nl) * 2012-03-27 2013-09-30 Jalila Essaidi Werkwijze ter vervaardiging van een huidsubstituut op basis van spinnenzijde alsmede draagstructuur vervaardigd onder toepassing van deze werkwijze en draagstructuur met doorgroeiende levende huid.
AU2013245785A1 (en) 2012-04-13 2014-10-23 Trustees Of Tufts College Methods and compositions for preparing a silk microsphere
WO2013163407A1 (en) 2012-04-25 2013-10-31 Trustees Of Tufts College Silk microspheres and methods for surface lubrication
WO2014012101A1 (en) 2012-07-13 2014-01-16 Trustees Of Tufts College Silk powder compaction for production of constructs with high mechanical strength and stiffness
WO2014035798A1 (en) 2012-08-30 2014-03-06 Sanofi Silk lyogels for sustained release of protein therapeutics and methods of making and uses
EP2925822A4 (en) 2012-11-27 2016-10-12 Univ Tufts INKS BASED ON BIOPOLYMERS AND THEIR USE
MX367597B (es) 2013-03-15 2019-08-28 Patheon Softgels Inc Cápsulas a base de seda.
US11376329B2 (en) 2013-03-15 2022-07-05 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
US10464361B2 (en) 2013-03-15 2019-11-05 Tufts University Silk water lithography
US11009792B2 (en) 2013-03-15 2021-05-18 Tufts University All water-based nanopatterning
ES2935659T3 (es) 2013-03-15 2023-03-09 Tufts College Composiciones de seda de bajo peso molecular y composiciones de seda estabilizadoras
CN103194068B (zh) * 2013-04-08 2015-12-23 浙江大学 一种稳定丝素蛋白溶液的方法
WO2014176458A2 (en) 2013-04-24 2014-10-30 Trustees Of Tufts College Bioresorbable biopolymer anastomosis devices
US10925999B2 (en) 2013-10-08 2021-02-23 Trustees Of Tufts College Tunable covalently crosslinked hydrogels and methods of making the same
US10513802B2 (en) 2013-11-08 2019-12-24 Tufts University Peptide-based nanofibrillar materials
CR20160468A (es) 2014-03-07 2017-01-20 Univ Tufts Conservación de productos perecederos a base de biopolímeros
EP3147369A4 (en) * 2014-05-21 2018-02-07 Ajinomoto Co., Inc. Fibroin-like protein production method
WO2016028797A1 (en) 2014-08-18 2016-02-25 Allergan, Inc. Pliable silk medical device
US10758645B2 (en) 2014-12-17 2020-09-01 Tufts University Injectable, flexible hydroxyapatite-silk foams for osteochondral and dental repair
ES2915384T3 (es) 2015-03-12 2022-06-22 Univ Tufts Materiales de seda con memoria de forma
EP3324907B1 (en) 2015-07-20 2021-09-22 Tufts University Biodegradable silk ear tubes
CN105231565B (zh) * 2015-10-20 2018-01-16 杭州华水布艺有限公司 一种含冰凉材料的防刺防护面料
WO2017123383A2 (en) 2015-12-17 2017-07-20 Trustees Of Tufts College Silk-fibroin hydrogels, methods of forming, and uses thereof
WO2017106631A1 (en) 2015-12-18 2017-06-22 Tufts University Silk solution purification system, concentrating system, and methods thereof
WO2017192227A1 (en) 2016-05-04 2017-11-09 Trustees Of Tufts College Silk nanofibrils and uses thereof
WO2018006037A1 (en) 2016-07-01 2018-01-04 Trustees Of Tufts College Innervated artificial skin
US11248313B2 (en) 2016-08-01 2022-02-15 Trustees Of Tufts College Biomimetic mechanical tension driven fabrication of nanofibrillar architecture
WO2018053524A1 (en) 2016-09-19 2018-03-22 Vaxess Technologies, Inc. Vaccine formulations with increased stability
WO2018081159A1 (en) 2016-10-24 2018-05-03 Trustees Of Tufts College Biomimetic multilayer compositions
WO2018081805A1 (en) 2016-10-31 2018-05-03 Sofregen Medical, Inc. Compositions comprising low molecular weight silk fibroin fragments and plasticizers
US20200000713A1 (en) 2017-01-20 2020-01-02 Massachusetts Institute Of Technology Injectable polymer micro-depots for controlled local drug delivery
WO2019067737A1 (en) * 2017-09-27 2019-04-04 Silk, Inc. MATERIALS COMPRISING RECOMBINANT SILK AND PROCESSES FOR PREPARING THE SAME
WO2019089567A1 (en) 2017-10-30 2019-05-09 Massachusetts Institute Of Technology Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
AU2019247655A1 (en) 2018-04-03 2020-10-01 Vaxess Technologies, Inc. Microneedle comprising silk fibroin applied to a dissolvable base
WO2020023906A2 (en) 2018-07-27 2020-01-30 Vaxess Technologies, Inc. Polymer-based biospecimen collection devices and uses thereof
US20220017580A1 (en) * 2018-11-28 2022-01-20 Bolt Threads, Inc. Alkaline purification of spider silk proteins
CN110106571A (zh) * 2019-04-09 2019-08-09 商文辉 一种蛛网纺织面料及其制备方法
WO2021002984A1 (en) 2019-05-30 2021-01-07 Massachusetts Institute Of Technology Peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids
WO2021076798A1 (en) 2019-10-15 2021-04-22 Sofregen Medical, Inc. Delivery devices for delivering and methods of delivering compositions
BR112022010919A2 (pt) 2019-12-06 2022-09-06 Tufts College Coquetel de múltiplos fármacos regenerativos de tecido e aparelho para a entrega deste
US20240104583A1 (en) 2022-09-26 2024-03-28 Massachusetts Institute Of Technology Integrating Biopolymer Design with Physical Unclonable Functions for Anticounterfeiting and Product Traceability

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991016351A1 (en) * 1990-04-19 1991-10-31 The United States Of America, Secretary Of The Army, The Pentagon Recombinant spider silk proteins through genetic engineering
DE69131969T2 (de) * 1990-04-20 2000-06-15 Univ Wyoming Laramie Für Spinnenseideprotein kodierende DNS, DNS enthaltender Vektor, transformierte Zelle und Produkte davon

Also Published As

Publication number Publication date
EP0848754A1 (en) 1998-06-24
JPH11511325A (ja) 1999-10-05
AU7152996A (en) 1997-03-19
CN1200145A (zh) 1998-11-25
WO1997008315A1 (en) 1997-03-06
BR9612625A (pt) 1999-06-01

Similar Documents

Publication Publication Date Title
IL123398A0 (en) Cloning methods for high strength spider silk proteins
GB9603518D0 (en) Novel process
GB9612514D0 (en) Novel process
AU5638496A (en) Viral vectors
AU2678097A (en) Targeted viral vectors
ZA984038B (en) Novel polyketide derivatives and recombinant methods for making same
PL312423A1 (en) Clamping ring
IL131000A0 (en) Method for preparing oxy-diphthalic anhydrides
HUP9702467A3 (en) Process for suspension copolymerization of ethylene
GB9510830D0 (en) Proteins
HUP0001837A3 (en) Novel dnas and process for producing proteins by using the same
EP0800761A4 (en) METHOD FOR CLONING PAPHIOPEDILA
EP0986389A4 (en) NEW PROCESS
AU1970497A (en) Amination process
GB9700690D0 (en) Novel process
AU7423796A (en) Novel stress proteins
AU9010998A (en) Sporting apparatus
AU4284397A (en) Process scheduler
GB9623359D0 (en) Novel process
GB9621822D0 (en) Novel process
HRP960329B1 (en) Process for the preparation of alpha, omega-bromochloroalcanes
AU5137598A (en) Novel protein
KR100220126B1 (en) Dyeing method of silk
AU2002313350A1 (en) Novel DNA cloning method
AU2847997A (en) High iron glasses