IL122974A - Optionally substituted tetrahydro-1H-naph[1,2,3-de]isoquinoline and pharmaceutical compositions containing them - Google Patents

Optionally substituted tetrahydro-1H-naph[1,2,3-de]isoquinoline and pharmaceutical compositions containing them

Info

Publication number
IL122974A
IL122974A IL12297496A IL12297496A IL122974A IL 122974 A IL122974 A IL 122974A IL 12297496 A IL12297496 A IL 12297496A IL 12297496 A IL12297496 A IL 12297496A IL 122974 A IL122974 A IL 122974A
Authority
IL
Israel
Prior art keywords
naph
isoquinoline
optionally substituted
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL12297496A
Other languages
English (en)
Other versions
IL122974A0 (en
Original Assignee
Purdue Research Foundation
Univ North Carolina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation, Univ North Carolina filed Critical Purdue Research Foundation
Publication of IL122974A0 publication Critical patent/IL122974A0/xx
Publication of IL122974A publication Critical patent/IL122974A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/18—Ring systems of four or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
IL12297496A 1995-08-18 1996-08-16 Optionally substituted tetrahydro-1H-naph[1,2,3-de]isoquinoline and pharmaceutical compositions containing them IL122974A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US251995P 1995-08-18 1995-08-18
PCT/US1996/013416 WO1997006799A1 (en) 1995-08-18 1996-08-16 Novel fused isoquinolines as dopamine receptor ligands

Publications (2)

Publication Number Publication Date
IL122974A0 IL122974A0 (en) 1998-08-16
IL122974A true IL122974A (en) 2000-11-21

Family

ID=21701148

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12297496A IL122974A (en) 1995-08-18 1996-08-16 Optionally substituted tetrahydro-1H-naph[1,2,3-de]isoquinoline and pharmaceutical compositions containing them

Country Status (18)

Country Link
US (2) US5959110A (de)
EP (1) EP0845988B1 (de)
JP (1) JP2000505046A (de)
CN (1) CN1199338A (de)
AT (1) ATE209915T1 (de)
AU (1) AU700688B2 (de)
BR (1) BR9610323A (de)
CA (1) CA2227585A1 (de)
DE (1) DE69617700T2 (de)
DK (1) DK0845988T3 (de)
ES (1) ES2169257T3 (de)
IL (1) IL122974A (de)
MX (1) MX9801179A (de)
NO (1) NO308658B1 (de)
NZ (1) NZ316312A (de)
PT (1) PT845988E (de)
RU (1) RU2177001C2 (de)
WO (1) WO1997006799A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ316312A (en) * 1995-08-18 1999-06-29 Purdue Research Foundation Novel fused isoquinolines as dopamine receptor ligands
KR20030027020A (ko) * 2000-08-11 2003-04-03 펄듀 리서치 파운데이션 디나프솔린의 제조 공정
CA2434736A1 (en) * 2001-01-16 2002-07-25 Purdue Research Foundation Method of treatment of dopamine-related dysfunction through administration of a full d1 dopamine receptor agonist and with no induction of tolerance
WO2003013532A1 (en) * 2001-08-10 2003-02-20 Purdue Research Foundation Chiral dinapsoline
EP1480647B1 (de) * 2002-02-15 2008-09-03 Darpharma, INC. Monoester und asymmetrisch substituierte diester prodrugs der dopamin-d1-rezeptor-agonisten
JP2004190007A (ja) * 2002-11-27 2004-07-08 Konica Minolta Holdings Inc 色素およびインクジェット記録液
EP1668363A1 (de) * 2003-09-24 2006-06-14 Biacore AB Verfahren und system zur analyse molekularer wechselwirkungen
NZ570606A (en) * 2006-02-21 2011-11-25 Purdue Research Foundation Trans-fused chromenoisoquinolines, synthesis and methods for use
PL2317852T3 (pl) * 2008-07-16 2015-05-29 Richter Gedeon Nyrt Preparaty farmaceutyczne zawierające ligandy receptora dopaminy
JP5734957B2 (ja) 2009-04-21 2015-06-17 パーデュー・リサーチ・ファウンデーションＰｕｒｄｕｅ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ ドーパミンレセプターのオクタヒドロベンゾイソキノリンモジュレーター及びその使用
CN110068645B (zh) * 2019-04-03 2021-09-03 上海药明奥测医疗科技有限公司 液质联用检测尿液中环磷酸腺苷的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4346090A (en) * 1977-07-21 1982-08-24 Ayerst, Mckenna & Harrison Ltd. 13-Chloro-benzocycloheptapyridoisoquinolines and use as neuroleptics
US5047536A (en) * 1989-03-17 1991-09-10 Purdue Research Foundation Hexahydrobenzo(A)phenanthridine compounds
IE912999A1 (en) * 1990-09-07 1992-03-11 Abbott Lab Phenanthridine compounds
DE69334206D1 (de) * 1992-05-26 2008-04-03 Purdue Research Foundation Substituierte hexahydrobenzo(a) phenanthridine
NZ316312A (en) * 1995-08-18 1999-06-29 Purdue Research Foundation Novel fused isoquinolines as dopamine receptor ligands

Also Published As

Publication number Publication date
PT845988E (pt) 2002-05-31
ES2169257T3 (es) 2002-07-01
IL122974A0 (en) 1998-08-16
DE69617700T2 (de) 2002-07-18
ATE209915T1 (de) 2001-12-15
MX9801179A (es) 1998-04-30
JP2000505046A (ja) 2000-04-25
NO980688L (no) 1998-02-18
AU6851396A (en) 1997-03-12
CN1199338A (zh) 1998-11-18
NO308658B1 (no) 2000-10-09
CA2227585A1 (en) 1997-02-27
BR9610323A (pt) 1999-12-21
EP0845988A1 (de) 1998-06-10
US5959110A (en) 1999-09-28
WO1997006799A1 (en) 1997-02-27
US6194423B1 (en) 2001-02-27
NO980688D0 (no) 1998-02-18
RU2177001C2 (ru) 2001-12-20
AU700688B2 (en) 1999-01-14
EP0845988B1 (de) 2001-12-05
DK0845988T3 (da) 2002-04-02
NZ316312A (en) 1999-06-29
EP0845988A4 (de) 1998-11-11
DE69617700D1 (de) 2002-01-17

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Legal Events

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MM9K Patent not in force due to non-payment of renewal fees