IL122296A0 - Quinolizinone type compounds - Google Patents
Quinolizinone type compoundsInfo
- Publication number
- IL122296A0 IL122296A0 IL12229696A IL12229696A IL122296A0 IL 122296 A0 IL122296 A0 IL 122296A0 IL 12229696 A IL12229696 A IL 12229696A IL 12229696 A IL12229696 A IL 12229696A IL 122296 A0 IL122296 A0 IL 122296A0
- Authority
- IL
- Israel
- Prior art keywords
- type compounds
- quinolizinone
- quinolizinone type
- compounds
- type
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/68—One oxygen atom attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46915995A | 1995-06-06 | 1995-06-06 | |
| US63811296A | 1996-05-29 | 1996-05-29 | |
| PCT/US1996/008991 WO1996039407A1 (en) | 1995-06-06 | 1996-06-05 | Quinolizinone type compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL122296A0 true IL122296A0 (en) | 1998-04-05 |
Family
ID=27042662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12229696A IL122296A0 (en) | 1995-06-06 | 1996-06-05 | Quinolizinone type compounds |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0871628A1 (de) |
| JP (1) | JPH11510478A (de) |
| KR (1) | KR19990022524A (de) |
| AU (1) | AU6153096A (de) |
| CA (1) | CA2222322A1 (de) |
| IL (1) | IL122296A0 (de) |
| MX (1) | MX9709416A (de) |
| WO (1) | WO1996039407A1 (de) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998002151A2 (en) | 1996-07-12 | 1998-01-22 | Leukosite, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US5693813A (en) * | 1997-02-26 | 1997-12-02 | Abbott Laboratories | Process for preparation of 4H-4-oxo-quinolizine-3-carboxylic acid |
| KR100241673B1 (ko) * | 1997-08-09 | 2000-03-02 | 김충섭 | 퀴놀리진 카르복실산 유도체 |
| JP4669607B2 (ja) | 1997-09-15 | 2011-04-13 | ザ プロクター アンド ギャンブル カンパニー | 抗微生物キノロン類、その組成物およびその使用 |
| EP1115724A1 (de) | 1998-09-21 | 2001-07-18 | Shire Biochem Inc. | Chinolizinone als integrinhemmer |
| CN1173971C (zh) * | 1998-11-24 | 2004-11-03 | 第一制药株式会社 | 环烷基取代的氨甲基吡咯烷衍生物 |
| RU2270695C2 (ru) | 1999-03-17 | 2006-02-27 | Дайити Фармасьютикал Ко., Лтд. | Фармацевтическая композиция |
| AU1996301A (en) | 1999-12-14 | 2001-06-25 | Neurosearch A/S | Novel heteroaryl-diazabicycloalkanes |
| DE19962470A1 (de) * | 1999-12-22 | 2001-07-12 | Schulz Hans Herrmann | Verwendung von Chemotherapeutika |
| SE0100326D0 (sv) * | 2001-02-02 | 2001-02-02 | Astrazeneca Ab | New compounds |
| US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| WO2003029253A1 (fr) * | 2001-09-28 | 2003-04-10 | Sato Pharmaceutical Co.,Ltd. | Antimicrobiens 4-oxoquinolizine comportant un squelette 2-pyridone comme structure partielle |
| US6900224B2 (en) * | 2002-07-31 | 2005-05-31 | The Procter & Gamble Company | Antimicrobial quinolones, their compositions and uses |
| CN1997642B (zh) * | 2003-09-22 | 2012-06-13 | 詹森药业有限公司 | 7-氨基亚烷基-杂环喹诺酮类和萘啶酮类 |
| EP1693364B1 (de) | 2003-12-12 | 2015-05-20 | Daiichi Sankyo Company, Limited | Zwischenprodukte für die herstellung von optisch aktiven cyclopropylaminderivaten und verfahren zur herstellung der zwischenprodukte |
| US7977346B2 (en) | 2006-01-17 | 2011-07-12 | Guoqing Paul Chen | Spiro compounds and methods of use |
| DK2001862T3 (da) | 2006-03-28 | 2011-08-08 | Warner Chilcott Co Llc | Malatsalte og polymorfe af (3S,5S)-7-[3-amino-5-methyl-piperidinyl]-1-cyklopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolincarboxylsyre |
| WO2007110835A2 (en) | 2006-03-28 | 2007-10-04 | The Procter & Gamble Company | A coupling process for preparing quinolone intermediates |
| CA2674369C (en) * | 2007-01-05 | 2012-04-03 | Daiichi Sankyo Company, Limited | Fused substituted aminopyrrolidine derivative |
| CN101622240B (zh) * | 2007-01-05 | 2014-07-23 | 第一三共株式会社 | 稠合取代氨基吡咯烷衍生物 |
| US8124807B2 (en) | 2007-12-26 | 2012-02-28 | Msd K.K. | Sulfonyl-substituted 6-membered ring derivative |
| JP5433992B2 (ja) * | 2008-06-26 | 2014-03-05 | Ｄｉｃ株式会社 | フルオロクロマノール誘導体の製造方法 |
| JP5433996B2 (ja) * | 2008-07-10 | 2014-03-05 | Ｄｉｃ株式会社 | フルオロフェノール誘導体の製造方法 |
| EP2423211B1 (de) * | 2009-04-20 | 2014-04-16 | Kaneka Corporation | Verfahren zur herstellung von (1s,6s)- oder (1r,6r)-cis-2,8-diazabicyclo[4.3.0]nonan und zwischenprodukt |
| US8796297B2 (en) | 2009-06-30 | 2014-08-05 | Abbvie Inc. | 4-substituted-2-amino-pyrimidine derivatives |
| WO2011031745A1 (en) | 2009-09-09 | 2011-03-17 | Achaogen, Inc. | Antibacterial fluoroquinolone analogs |
| JP5487425B2 (ja) * | 2009-09-11 | 2014-05-07 | 毅 野田 | 光学活性２−置換−３−アミノピペリジン誘導体および製造方法 |
| DK2491038T3 (da) | 2009-10-23 | 2016-07-18 | Janssen Pharmaceutica Nv | Disubstituerede octahydropyrrolo [3,4-c]pyrroler som orexin receptormodulatorer |
| PE20142364A1 (es) | 2012-02-10 | 2015-01-10 | Hoffmann La Roche | Compuestos para tratar atrofia muscular espinal |
| EP4249472A3 (de) | 2015-05-30 | 2023-12-13 | PTC Therapeutics, Inc. | Verfahren zur modulation von rna-spleissen |
| IL281633B (en) | 2015-12-10 | 2022-07-01 | Ptc Therapeutics Inc | Methods for treating Huntington's disease |
| CA3016706A1 (en) | 2016-03-10 | 2017-09-14 | Janssen Pharmaceutica Nv | Methods of treating depression using orexin-2 receptor antagonists |
| CN106543170B (zh) * | 2016-10-27 | 2018-02-23 | 丹诺医药(苏州）有限公司 | 8‑氯‑1‑环丙基‑7‑氟‑9‑甲基‑4‑氧‑4‑氢‑喹嗪‑3‑羧酸酯及其合成方法 |
| EP3544435A4 (de) | 2016-11-28 | 2020-11-04 | PTC Therapeutics, Inc. | Verfahren zur modulation von rna-splicing |
| EP3634953B1 (de) | 2017-06-05 | 2024-01-03 | PTC Therapeutics, Inc. | Verbindungen zur behandlung von morbus huntington |
| CN111372611A (zh) | 2017-06-14 | 2020-07-03 | Ptc医疗公司 | 修饰rna剪接的方法 |
| US11395822B2 (en) | 2017-06-28 | 2022-07-26 | Ptc Therapeutics, Inc. | Methods for treating Huntington's disease |
| CA3067591A1 (en) | 2017-06-28 | 2019-01-03 | Ptc Therapeutics, Inc. | Methods for treating huntington's disease |
| CA3094703A1 (en) | 2018-03-27 | 2019-10-03 | Ptc Therapeutics, Inc. | Compounds for treating huntington's disease |
| WO2020005873A1 (en) | 2018-06-27 | 2020-01-02 | Ptc Therapeutics, Inc. | Heterocyclic and heteroaryl compounds for treating huntington's disease |
| US11685746B2 (en) | 2018-06-27 | 2023-06-27 | Ptc Therapeutics, Inc. | Heteroaryl compounds for treating Huntington's disease |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE911472A1 (en) * | 1990-05-02 | 1991-11-06 | Abbott Lab | Quinolizinone type compounds |
| BR9407806A (pt) * | 1993-10-14 | 1997-08-19 | Abbott Lab | Composto processo de tratamento de uma infecção bacteriana em um paciente humano ou veterinário e intermediário sintético |
-
1996
- 1996-06-05 CA CA002222322A patent/CA2222322A1/en not_active Abandoned
- 1996-06-05 WO PCT/US1996/008991 patent/WO1996039407A1/en not_active Application Discontinuation
- 1996-06-05 IL IL12229696A patent/IL122296A0/xx unknown
- 1996-06-05 KR KR1019970709005A patent/KR19990022524A/ko not_active Application Discontinuation
- 1996-06-05 JP JP9501420A patent/JPH11510478A/ja active Pending
- 1996-06-05 AU AU61530/96A patent/AU6153096A/en not_active Abandoned
- 1996-06-05 EP EP96919103A patent/EP0871628A1/de not_active Withdrawn
-
1997
- 1997-12-02 MX MX9709416A patent/MX9709416A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR19990022524A (ko) | 1999-03-25 |
| CA2222322A1 (en) | 1996-12-12 |
| AU6153096A (en) | 1996-12-24 |
| MX9709416A (es) | 1998-07-31 |
| EP0871628A1 (de) | 1998-10-21 |
| JPH11510478A (ja) | 1999-09-14 |
| WO1996039407A1 (en) | 1996-12-12 |
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