IL122291A - 3-acylamino-1-phenyl-9-substituted-3,4,6,7-tetrahydro¬1,4¾diazepino¬6,7,1-hi¾indol-4-ones their preparation and pharmaceutical compositions containing them - Google Patents

3-acylamino-1-phenyl-9-substituted-3,4,6,7-tetrahydro¬1,4¾diazepino¬6,7,1-hi¾indol-4-ones their preparation and pharmaceutical compositions containing them

Info

Publication number
IL122291A
IL122291A IL12229197A IL12229197A IL122291A IL 122291 A IL122291 A IL 122291A IL 12229197 A IL12229197 A IL 12229197A IL 12229197 A IL12229197 A IL 12229197A IL 122291 A IL122291 A IL 122291A
Authority
IL
Israel
Prior art keywords
nr2r3
substituted
acylamino
tetrahydro
ones
Prior art date
Application number
IL12229197A
Other languages
English (en)
Other versions
IL122291A0 (en
Original Assignee
Jouveinal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jouveinal filed Critical Jouveinal
Publication of IL122291A0 publication Critical patent/IL122291A0/xx
Priority to IL13743700A priority Critical patent/IL137437A0/xx
Publication of IL122291A publication Critical patent/IL122291A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
IL12229197A 1996-03-29 1997-03-27 3-acylamino-1-phenyl-9-substituted-3,4,6,7-tetrahydro¬1,4¾diazepino¬6,7,1-hi¾indol-4-ones their preparation and pharmaceutical compositions containing them IL122291A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL13743700A IL137437A0 (en) 1996-03-29 2000-07-21 Aminodiazepinoindoles and their use in the preparation of [1,4] diazepino [6,7,1-hi] indoles

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9604013A FR2746800B1 (fr) 1996-03-29 1996-03-29 Diazepino-indoles inhibiteurs de phosphodiesterases 4
PCT/FR1997/000557 WO1997036905A1 (fr) 1996-03-29 1997-03-27 Diazepino-indoles inhibiteurs de phosphodiesterases 4

Publications (2)

Publication Number Publication Date
IL122291A0 IL122291A0 (en) 1998-04-05
IL122291A true IL122291A (en) 2000-12-06

Family

ID=9490742

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12229197A IL122291A (en) 1996-03-29 1997-03-27 3-acylamino-1-phenyl-9-substituted-3,4,6,7-tetrahydro¬1,4¾diazepino¬6,7,1-hi¾indol-4-ones their preparation and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US5972927A (xx)
EP (2) EP0828742B1 (xx)
JP (1) JP2001510441A (xx)
KR (1) KR19990022100A (xx)
CN (1) CN1066149C (xx)
AT (1) ATE211141T1 (xx)
AU (1) AU735631B2 (xx)
BR (1) BR9702180A (xx)
CA (1) CA2220407A1 (xx)
DE (1) DE69709272T2 (xx)
DK (1) DK0828742T3 (xx)
EA (2) EA002189B1 (xx)
ES (1) ES2168627T3 (xx)
FR (1) FR2746800B1 (xx)
HK (1) HK1018051A1 (xx)
IL (1) IL122291A (xx)
NZ (1) NZ329532A (xx)
PT (1) PT828742E (xx)
WO (1) WO1997036905A1 (xx)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA02001830A (es) 1999-08-21 2002-08-12 Byk Gulden Lomberg Chem Fab Combinacion sinergica de inhibidores de pde y agonista de beta 2 adrenoceptor.
WO2001064669A1 (en) 2000-03-03 2001-09-07 Pfizer Products Inc. Pyrazole ether derivatives as anti-inflammatory/analgesic agents
EP1161950A1 (en) * 2000-06-09 2001-12-12 Warner-Lambert Company Use of diazepinoindoles for the treatment of chronic obstructive pulmonary disease
EP1161949A1 (en) * 2000-06-09 2001-12-12 Warner-Lambert Company Use od diazepinoindoles for the treatment of chronic obstructive pulmonary disease
US6953774B2 (en) * 2000-08-11 2005-10-11 Applied Research Systems Ars Holding N.V. Methods of inducing ovulation
EP1199074A1 (en) * 2000-09-15 2002-04-24 Warner-Lambert Company Pharmaceutical composition for preventing or treating a disease associated with an excess of il-12 production
EP1188438A1 (en) * 2000-09-15 2002-03-20 Warner-Lambert Company Pharmaceutical composition for preventing or treating a disease associated with an excess of Il-12 production
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
KR101179012B1 (ko) 2003-03-10 2012-09-03 니코메드 게엠베하 로플루미라스트 신규한 제조 방법
US8158814B2 (en) 2003-08-29 2012-04-17 Mitsui Chemicals, Inc. Insecticide for agricultural or horticultural use and method of use thereof
EP1861074B1 (en) 2005-03-16 2013-04-24 Takeda GmbH Taste masked dosage form containing roflumilast
CA2620333A1 (en) 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
EP1940389A2 (en) 2005-10-21 2008-07-09 Braincells, Inc. Modulation of neurogenesis by pde inhibition
WO2007053596A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
CA2651813A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
EP2026813A2 (en) 2006-05-09 2009-02-25 Braincells, Inc. 5 ht receptor mediated neurogenesis
EP2068872A1 (en) 2006-09-08 2009-06-17 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US20090182035A1 (en) * 2007-04-11 2009-07-16 Alcon Research, Ltd. Use of a combination of olopatadine and cilomilast to treat non-infectious rhinitis and allergic conjunctivitis
WO2008127975A2 (en) * 2007-04-11 2008-10-23 Alcon Research, Ltd. Use of an inhibitor of tnfa plus an antihistamine to treat allergic rhinitis and allergic conjunctivitis
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
EP2482798A1 (en) * 2009-10-01 2012-08-08 Alcon Research, Ltd. Olopatadine compositions and uses thereof
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
CN117757730B (zh) * 2023-12-26 2024-06-07 浙江普罗亭健康科技有限公司 一种人心脏组织消化专用试剂盒及消化方法、检测方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4840947A (en) * 1986-10-14 1989-06-20 Hoechst-Roussel Pharmaceuticals, Inc. Antiinflammatory and analgesic piperidin-4-yl-tetracyclic benzodiazepines and use thereas
FR2652352A1 (fr) * 1989-09-28 1991-03-29 Jouveinal Sa Benzodiazepines, leur procede et intermediaires de preparation et leurs applications en therapeutique.
FR2725719B1 (fr) * 1994-10-14 1996-12-06 Jouveinal Inst Rech Diazepino-indoles inhibiteurs de phosphodiesterases iv

Also Published As

Publication number Publication date
EA002189B1 (ru) 2002-02-28
IL122291A0 (en) 1998-04-05
KR19990022100A (ko) 1999-03-25
EA199700346A1 (ru) 1998-10-29
WO1997036905A1 (fr) 1997-10-09
DK0828742T3 (da) 2002-04-15
EA199900624A1 (ru) 2000-06-26
CN1189832A (zh) 1998-08-05
US5972927A (en) 1999-10-26
NZ329532A (en) 2000-03-27
AU2391397A (en) 1997-10-22
EA001593B1 (ru) 2001-06-25
EP1132390A3 (fr) 2001-10-10
EP0828742A1 (fr) 1998-03-18
PT828742E (pt) 2002-06-28
DE69709272T2 (de) 2002-08-08
EP0828742B1 (fr) 2001-12-19
ATE211141T1 (de) 2002-01-15
AU735631B2 (en) 2001-07-12
BR9702180A (pt) 1999-12-28
ES2168627T3 (es) 2002-06-16
CN1066149C (zh) 2001-05-23
JP2001510441A (ja) 2001-07-31
FR2746800B1 (fr) 1998-06-05
HK1018051A1 (en) 1999-12-10
CA2220407A1 (fr) 1997-10-09
DE69709272D1 (de) 2002-01-31
FR2746800A1 (fr) 1997-10-03
EP1132390A2 (fr) 2001-09-12

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